4.9
4.6The cheapest and fastest buses from St. Louis, MO to Des Moines, IA
Cheapest price
$168
Average price
$213
Fastest journey
10 h 25 m
Average duration
12 h 4 m
Buses per day
3
Distance
440 km
The best way to find a cheap bus ticket from St. Louis, MO to Des Moines, IA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Des Moines, IA will cost around $213 if you buy it on the day, but the cheapest tickets can be found for only $168.
It's difficult to get from St. Louis, MO to Des Moines, IA without transferring at least once.
Live departures
St. Louis, MO to Des Moines, IA bus times
The table below shows live departures for St. Louis, MO to Des Moines, IA buses for today, Tuesday, November 25. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 6:52 AM St. Louis, MO | 10h43 | 5:35 PM Des Moines, IA | 2 transfers | |
| 7:40 AM St. Louis, MO | 15h05 | 10:45 PM Des Moines, IA | 1 transfer | |
| Wednesday, November 26 | |||||
| 1:30 AM St. Louis, MO | 10h25 | 11:55 AM Des Moines, IA | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Des Moines, IA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 26
Nov 27
Nov 28
Nov 29
Nov 30
Dec 01
Dec 02
Journey information
Overview: Bus from St. Louis, MO to Des Moines, IA
USAUSA
Buses from St. Louis, MO to Des Moines, IA run on average 1 times per day, taking around 15h 0m. Cheap bus tickets for this journey start at $169 (€138) if you book in advance.
The earliest bus runs at 05:30, the last at 23:30. The fastest bus covers the 273 miles (440 km) distance in 10h 25m.
Distance 273 miles (440 km) |
Average bus duration 15h 0m |
Cheapest ticket price $169 (€138) |
Buses per day 1 |
Fastest bus 10h 25m |
First bus 05:30 |
Last bus 23:30 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from St. Louis, MO to Des Moines, IA start from as low as $169 (€138) if booked well in advance.
- Standard Fares: Typically, trains cost $215 (€176) depending on the train type and class.
Journey Duration & Frequency
- On average there are 1 daily trains from St. Louis, MO to Des Moines, IA with 0 direct service.
- The fastest trains can take as little as 10h 25m but the average duration is 15h 0m
Train Operators
- Travel from St. Louis, MO to Des Moines, IA with Greyhound and Metro St. Louis
- The most booked train company for this route on Omio is Greyhound.
Stations & Schedule
- Most trains depart from St. Louis, S 15th St (Civic center) and arrive in Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA
- First train typically departs at 05:30 AM and the last at 11:30 PM
Bus providers: Greyhound, Metro St. Louis from St. Louis, MO to Des Moines, IAYou can travel by bus between St. Louis, MO to Des Moines, IA with Greyhound, Metro St. Louis for as low as $169 (€138). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
Metro St. Louis
FAQs: Bus from St. Louis, MO to Des Moines, IA
Find answers to the most common questions about traveling from St. Louis, MO to Des Moines, IA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Des Moines, IA, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from St. Louis, MO to Des Moines, IA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from St. Louis, MO to Des Moines, IA
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Des Moines, IA
Here are some other resources that might have the information you need
Most popular buses to and from Des Moines, IA and St. Louis, MO
Most popular bus connections to Des Moines, IA
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
