The cheapest and fastest buses from Philadelphia, PA to Des Moines, IA
Cheapest price
$186
Average price
$198
Fastest journey
1 d 10 h 30 m
Average duration
1 d 11 h 48 m
Buses per day
3
Distance
1561 km
The best way to find a cheap bus ticket from Philadelphia, PA to Des Moines, IA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Philadelphia, PA to Des Moines, IA will cost around $198 if you buy it on the day, but the cheapest tickets can be found for only $186.
Of the 3 buses that leave Philadelphia, PA for Des Moines, IA on Thu, Feb 05, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Feb 05 the direct buses cover the 1561 km distance in an average of 1 d 11 h 48 m but if you time it right, some buses will get you there in just 1 d 10 h 30 m .
On Thu, Feb 05 the slowest buses will take 1 d 13 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Travel Information
Compare bus and flight for Philadelphia, PA to Des Moines, IA
Omio recommends booking the flight as it is the most popular option from Philadelphia, PA to Des Moines, IA among Omio's users. If you are prioritising price take the bus with prices starting from €144. For those with little time consider booking a flight which can get you there in 4h 7m. The ticket price range depends on the travel mode: a bus costs an average of €144, and a flight costs an average of €156.
Distance: 969 miles (1561 km)
Compare bus with
| Bus | Most popular Flight |
|---|---|
€165 Average price Cheapest | €280 Average price |
32h 10m Average total duration 31h 40m Onboard + 30m Additional time* | 7h 7m Average total duration Fastest 4h 7m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
Live departures
Philadelphia, PA to Des Moines, IA bus times
The table below shows live departures for Philadelphia, PA to Des Moines, IA buses for tomorrow, Thursday, February 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:10 AM Philadelphia, PA | 37h45 | 8:55 PM Des Moines, IA | 0 transfersDirect | |
![]() | 8:25 AM Philadelphia, PA | 35h10 | 7:35 PM Des Moines, IA | 0 transfersDirect | |
![]() | 9:05 AM Philadelphia, PA | 34h30 | 7:35 PM Des Moines, IA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Philadelphia, PA to Des Moines, IA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 05
Feb 06
Feb 07
Feb 08
Feb 09
Feb 10
Feb 11
Why should you book Philadelphia, PA to Des Moines, IA buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of SEPTA or Peter Pan Bus to find the best option for your trip from Philadelphia, PA to Des Moines, IA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Philadelphia, PA to Des Moines, IA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Philadelphia, PA to Des Moines, IA.
Journey information
Overview: Bus from Philadelphia, PA to Des Moines, IA
Buses from Philadelphia, PA to Des Moines, IA run on average 3 times per day, taking around 31h 40m. Cheap bus tickets for this journey start at $182 (€144) if you book in advance.
The earliest bus runs at 01:45, the last at 23:45. The fastest bus covers the 969 miles (1561 km) distance in 26h 5m.
Distance 969 miles (1561 km) |
Average bus duration 31h 40m |
Cheapest ticket price $182 (€144) |
Buses per day 3 |
Fastest bus 26h 5m |
First bus 01:45 |
Last bus 23:45 |
Bus providers: Greyhound, SEPTA, Peter Pan Bus from Philadelphia, PA to Des Moines, IAYou can travel by bus between Philadelphia, PA to Des Moines, IA with Greyhound, SEPTA, Peter Pan Bus for as low as $182 (€144). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
Peter Pan Bus
SEPTA
FAQs: Bus from Philadelphia, PA to Des Moines, IA
Find answers to the most common questions about traveling from Philadelphia, PA to Des Moines, IA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Des Moines, IA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Peter Pan Bus
- All Peter Pan buses are wheelchair accessible and can accommodate both manual and power wheelchairs, with a maximum combined weight of 650 lbs for the person and chair.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Peter Pan Bus
- All Peter Pan tickets are non-refundable unless a refundable fare option was specifically purchased.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Peter Pan Bus
- Each ticketed passenger is allowed one carry-on bag (up to 25 lbs) and one stowed bag (up to 50 lbs) for free.
- Greyhound
- $15 per additional bag.
- Peter Pan Bus
- Additional stowed bags are allowed, limited to three extra items, for a fee of $5.00 each, with a maximum weight of 50 lbs per bag.
- Peter Pan Bus
- Small dogs and cats are allowed on board in a carrier.
popular bus stations
Popular bus stations from Philadelphia, PA to Des Moines, IA
Most popular bus connections from Philadelphia, PA
More options for your journey from Philadelphia, PA to Des Moines, IA
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