Compare prices and tickets Detroit, MI to Des Moines, IA by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Detroit, MI to Des Moines, IA buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of to find the best option for your trip from Detroit, MI to Des Moines, IA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Wanderu?
Journey information
Overview: Bus from Detroit, MI to Des Moines, IA
Buses from Detroit, MI to Des Moines, IA run on average 1 times per day, taking around 16h 55m. Cheap bus tickets for this journey start at $325 (€259) if you book in advance.
The earliest bus runs at 05:30, the last at 23:25. The fastest bus covers the 544 miles (877 km) distance in 23h 35m.
Distance 544 miles (877 km) |
Average bus duration 16h 55m |
Cheapest ticket price $325 (€259) |
Buses per day 1 |
Fastest bus 23h 35m |
First bus 05:30 |
Last bus 23:25 |
Bus providers: Greyhound from Detroit, MI to Des Moines, IAYou can travel by bus between Detroit, MI to Des Moines, IA with Greyhound for as low as $325 (€259). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Detroit, MI to Des Moines, IA
Find answers to the most common questions about traveling from Detroit, MI to Des Moines, IA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Des Moines, IA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Detroit, MI to Des Moines, IA
Most popular bus connections from Detroit, MI
More options for your journey from Detroit, MI to Des Moines, IA
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