Journey information
Overview: Bus from San Diego, CA to Des Moines, IA
Take a bus from San Diego, CA to Des Moines, IA and enjoy the approximately 1428 miles (2299 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 05:30, the last at 19:35.
Distance 1428 miles (2299 km) |
Average bus duration 61h 30m |
Buses per day 5 |
First bus 05:30 |
Last bus 19:35 |
Key Takeaways
Journey Duration & Frequency
- On average there are 5 daily trains from San Diego, CA to Des Moines, IA with 0 direct service.
- The fastest trains can take as little as 0m but the average duration is 61h 30m
Train Operators
- Travel from San Diego, CA to Des Moines, IA with Greyhound
- The most booked train company for this route on Omio is Greyhound.
Stations & Schedule
- First train typically departs at 05:30 AM and the last at 07:35 PM
Bus providers: Greyhound from San Diego, CA to Des Moines, IAYou can travel by bus between San Diego, CA to Des Moines, IA with Greyhound. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from San Diego, CA to Des Moines, IA
Find answers to the most common questions about traveling from San Diego, CA to Des Moines, IA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Des Moines, IA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from San Diego, CA to Des Moines, IA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
More options for your journey from San Diego, CA to Des Moines, IA
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