4.9
4.6The cheapest and fastest buses from San Diego, CA to Des Moines, IA
Cheapest price
$481
Average price
$481
Fastest journey
2 d 13 h 30 m
Average duration
2 d 13 h 30 m
Buses per day
1
Distance
2299 km
The best way to find a cheap bus ticket from San Diego, CA to Des Moines, IA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Diego, CA to Des Moines, IA will cost around $481 if you buy it on the day, but the cheapest tickets can be found for only $481.
It's difficult to get from San Diego, CA to Des Moines, IA without transferring at least 3 times.
7:25 PM61h30San Diego, CA8:55 AMDes Moines, IA$4811One-way3 transfers
- 7:25 PM61h30San Diego, CA8:55 AMDes Moines, IA$4811One-way3 transfers
Travel Information
Compare bus and flight for San Diego, CA to Des Moines, IA
Omio recommends booking the flight as it is the most popular option from San Diego, CA to Des Moines, IA among Omio's users. If you are prioritising price take the bus with prices starting from $233. For those with little time consider booking a flight which can get you there in 3h 49m. The ticket price range depends on the travel mode: a bus costs an average of $233, and a flight costs an average of $595.
Distance: 1428 miles (2299 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
$233 Average price Cheapest | $595 Average price | $351 Average price (fuel + tolls) |
62h 0m Average total duration 61h 30m Onboard + 30m Additional time* | 6h 49m Average total duration Fastest 3h 49m Onboard + 3h 0m Additional time* | 25h 7m Average total duration (door-to-door) |
Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Diego, CA to Des Moines, IA:
A bus is $362 (€298) less than a flight for this route with tickets for a flight from San Diego, CA to Des Moines, IA costing on average $595 (€490).
Other travel options to Des Moines, IA take longer:
Bus takes on average 61h 30m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
San Diego, CA to Des Moines, IA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound Mexico | Departure Time 07:25PM | Arrival Time 08:55AM | Duration 61h30 | Departure days Tue, Wed, Fri | Cheapest price $481 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 01:55PM | Duration 41h45 | Departure days Thu | Cheapest price $233 |
Live departures
San Diego, CA to Des Moines, IA bus times
The table below shows live departures for San Diego, CA to Des Moines, IA buses for today, Tuesday, July 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 7:25 PM San Diego, CA | 61h30 | 8:55 AM Des Moines, IA | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Diego, CA to Des Moines, IA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jul 15
Jul 16
Jul 17
Jul 18
Jul 19
Jul 20
Jul 21
Why should you book San Diego, CA to Des Moines, IA buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from San Diego, CA to Des Moines, IA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from San Diego, CA to Des Moines, IA.
Journey information
Overview: Bus from San Diego, CA to Des Moines, IA
USAUSA
Buses from San Diego, CA to Des Moines, IA run on average 4 times per day, taking around 61h 30m. Cheap bus tickets for this journey start at $233 (€192) if you book in advance.
The earliest bus runs at 05:30, the last at 19:35. The fastest bus covers the 1428 miles (2299 km) distance in 41h 45m.
Distance 1428 miles (2299 km) |
Average bus duration 61h 30m |
Cheapest ticket price $233 (€192) |
Buses per day 4 |
Fastest bus 41h 45m |
First bus 5:30 AM |
Last bus 7:35 PM |
Cheapest Month Aug |
Cheapest Day Mon |
High Season Apr - Jun |
Low Season Jan - Mar |
Bus providers: Greyhound from San Diego, CA to Des Moines, IAYou can travel by bus between San Diego, CA to Des Moines, IA with Greyhound for as low as $233 (€192). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from San Diego, CA to Des Moines, IA
Find answers to the most common questions about traveling from San Diego, CA to Des Moines, IA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Des Moines, IA, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from San Diego, CA to Des Moines, IA
Most San Diego, CA to Des Moines, IA buses use the San Diego, Congress Street (Old Town Park) to station pair. Use this guide to compare San Diego, CA and Des Moines, IA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Getting to San Diego, Congress Street (Old Town Park) from San Diego city centre
Getting to San Diego, San Ysidro Transit Center from San Diego city centre
More options for your journey from San Diego, CA to Des Moines, IA
Here are some other resources that might have the information you need
Most popular buses to and from Des Moines, IA and San Diego, CA
Most popular bus connections to Des Moines, IA
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