San Diego, CA to Des Moines, IA bus with Greyhound

Thu, Feb 26
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1,000+ travel companies
Greyhound
FlixBus
Costa Verde
Alsa
BlaBlaCar Bus
1,000+ travel companies
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Why should you book San Diego, CA to Des Moines, IA buses with Omio?

Greyhound operates all buses services from San Diego, CA to Des Moines, IA.
Omio is an official ticket reseller for all your travel options from San Diego, CA to Des Moines, IA.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.

Journey information

Overview: Bus from San Diego, CA to Des Moines, IA

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Take a bus from San Diego, CA to Des Moines, IA and enjoy the approximately 1428 miles (2299 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 05:30, the last at 19:15.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
1428 miles (2299 km)
Average bus duration
61h 30m
Buses per day
5
First bus
05:30
Last bus
19:15
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from San Diego, CA to Des Moines, IAYou can travel by bus between San Diego, CA to Des Moines, IA with Greyhound. When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
73h 35m
Cheapest Price
$313 (€250)
Greyhound frequency
5 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from San Diego, CA to Des Moines, IA

Find answers to the most common questions about traveling from San Diego, CA to Des Moines, IA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Des Moines, IA, this guide helps you travel smarter and with confidence.

FAQs
The earliest bus from San Diego, CA to Des Moines, IA leaves at 5:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Diego, CA to Des Moines, IA leaves at 7:15 PM.
There are 5 buses a day from San Diego, CA to Des Moines, IA which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Diego, CA to Des Moines, IA, you can count on Greyhound for the best way to get you to Des Moines, IA. You can also check all possible bus companies who offer a service between San Diego, CA and Des Moines, IA and compare the amenities they offer before buying a bus ticket.
The cheapest month for a bus from San Diego, CA to Des Moines, IA is August.
Yes, you can take a between San Diego, CA and Des Moines, IA.
Yes, the following accessibility options are available when taking the bus from San Diego, CA to Des Moines, IA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from San Diego, CA to Des Moines, IA for bus company Greyhound.
Whether you can cancel your bus ticket from San Diego, CA to Des Moines, IA depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from San Diego, CA to Des Moines, IA.
Yes, the following luggage options are included when booking a bus ticket from San Diego, CA to Des Moines, IA:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from San Diego, CA to Des Moines, IA:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from San Diego, CA to Des Moines, IA.
You can reserve your seat on the bus from San Diego, CA to Des Moines, IA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from San Diego, CA to Des Moines, IA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from San Diego, CA to Des Moines, IA with the following bus company: Greyhound.

Most popular buses to and from Des Moines, IA and San Diego, CA

Most popular bus connections to Des Moines, IA

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