4.9
4.6
Travel Information
Compare bus and flight for San Diego, CA to Des Moines, IA
Omio recommends booking the flight as it is the most popular option from San Diego, CA to Des Moines, IA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €167 For those with little time, consider booking a flight, which has an average total journey time of 7h 32m. Average ticket prices depend on the travel mode: a bus costs an average of €167, while a flight costs an average of €419.
Distance: 1428 miles (2299 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
€167 Average price Cheapest | €419 Average price | €293 Average price (fuel + tolls) |
39h 1m Average total duration 38h 31m Onboard + 30m Additional time* | 7h 32m Average total duration Fastest 5h 32m Onboard + 2h 0m Additional time* | 25h 7m Average total duration (door-to-door) |
 Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Diego, CA to Des Moines, IA:
A bus is €252 less than a flight for this route with tickets for a flight from San Diego, CA to Des Moines, IA costing on average €419.
Other travel options to Des Moines, IA take longer:
Bus takes on average 38h 31m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
San Diego, CA to Des Moines, IA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 05:40AM | Arrival Time 08:55AM | Duration 49h15 | Departure days Fri | Cheapest price €196 |
Operator Greyhound | Departure Time 09:25AM | Arrival Time 08:55AM | Duration 45h30 | Departure days Fri | Cheapest price €198 |
Operator Greyhound | Departure Time 12:40PM | Arrival Time 08:55AM | Duration 42h15 | Departure days Fri | Cheapest price €188 |
Operator Greyhound | Departure Time 01:10PM | Arrival Time 08:55AM | Duration 41h45 | Departure days Fri | Cheapest price €197 |
Operator Greyhound Mexico | Departure Time 07:25PM | Arrival Time 08:55AM | Duration 61h30 | Departure days Tue, Wed | Cheapest price €396 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 01:55PM | Duration 41h45 | Departure days Thu | Cheapest price €192 |
Operator Greyhound | Departure Time 09:15PM | Arrival Time 08:55AM | Duration 57h40 | Departure days Fri | Cheapest price €224 |
Operator Greyhound | Departure Time 09:45PM | Arrival Time 08:55AM | Duration 57h10 | Departure days Fri | Cheapest price €233 |
Operator Greyhound | Departure Time 10:05PM | Arrival Time 08:55AM | Duration 56h50 | Departure days Fri | Cheapest price €233 |
Live departures
San Diego, CA to Des Moines, IA bus times
The table below shows live departures for San Diego, CA to Des Moines, IA buses for today, Friday, August 28. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 FlixBus · FlixBus+ · | 9:25 AM San Diego, Congress Street (Old Town Park), CA | 45h30 | 8:55 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 4 transfers | |
| FlixBus+ · · | 12:40 PM San Diego, San Ysidro Transit Center | 42h15 | 8:55 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 3 transfers | |
| FlixBus+ · · | 1:10 PM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA | 41h45 | 8:55 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 3 transfers | |
| FlixBus+ · · | 9:15 PM San Diego, San Ysidro Transit Center | 57h40 | 8:55 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 3 transfers | |
| FlixBus+ · · | 9:45 PM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA | 57h10 | 8:55 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 3 transfers | |
| FlixBus+ · · | 10:05 PM San Diego, Congress Street (Old Town Park), CA | 56h50 | 8:55 AM Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Diego, CA to Des Moines, IA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Aug 29
Aug 30
Aug 31
Sep 01
Sep 02
Sep 03
Sep 04
Why should you book San Diego, CA to Des Moines, IA buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from San Diego, CA to Des Moines, IA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from San Diego, CA to Des Moines, IA.
Journey information
Overview: Bus from San Diego, CA to Des Moines, IA
USAUSA
Buses from San Diego, CA to Des Moines, IA run on average 4 times per day, taking around 38h 31m. Cheap bus tickets for this journey start at €148 if you book in advance.
The earliest bus runs at 05:30, the last at 19:35. The fastest bus covers the 1428 miles (2299 km) distance in 38h 0m.
Distance 1428 miles (2299 km) |
Average bus duration 38h 31m |
Cheapest ticket price €148 |
Buses per day 4 |
Fastest bus 38h 0m |
First bus 5:30 AM |
Last bus 7:35 PM |
Cheapest Month May |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Jan - Mar |
Bus providers: Greyhound from San Diego, CA to Des Moines, IAYou can travel by bus between San Diego, CA to Des Moines, IA with Greyhound for as low as €148. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from San Diego, CA to Des Moines, IA
Find answers to the most common questions about traveling from San Diego, CA to Des Moines, IA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Des Moines, IA, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from San Diego, CA to Des Moines, IA
Most San Diego, CA to Des Moines, IA buses use the San Diego, Congress Street (Old Town Park) to Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) station pair. Use this guide to compare San Diego, CA and Des Moines, IA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which San Diego, CA station do buses to Des Moines, IA leave from?
Getting to San Diego, Congress Street (Old Town Park) from San Diego city centre
San Diego, Congress Street (Old Town Park) is 5 km from San Diego city centre. Public transport options include:
San Diego, Congress Street (Old Town Park) bus station facilities and services
San Diego, Congress Street (Old Town Park) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several dining options nearby.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, Congress Street (Old Town Park). ATMs are available at San Diego, Congress Street (Old Town Park).
Tickets and information
Ticket office support is available at San Diego, Congress Street (Old Town Park).
Parking, taxis and toilets
Available at San Diego, Congress Street (Old Town Park): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, Congress Street (Old Town Park): Wheelchair accessible routes available.
Getting to San Diego, West Harbor Drive (The Headquarters at Seaport District) from San Diego city centre
San Diego, West Harbor Drive (The Headquarters at Seaport District) is 1 km from San Diego city centre. Public transport options include:
San Diego, West Harbor Drive (The Headquarters at Seaport District) bus station facilities and services
San Diego, West Harbor Drive (The Headquarters at Seaport District) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several dining options are in the area.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, West Harbor Drive (The Headquarters at Seaport District). ATMs are available at San Diego, West Harbor Drive (The Headquarters at Seaport District).
Tickets and information
Ticket office support is available at San Diego, West Harbor Drive (The Headquarters at Seaport District).
Parking, taxis and toilets
Available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Accessible for persons with disabilities.
Getting to San Diego, San Ysidro Transit Center from San Diego city centre
San Diego, San Ysidro Transit Center is 22 km from San Diego city centre. Public transport options include:
San Diego, San Ysidro Transit Center bus station facilities and services
San Diego, San Ysidro Transit Center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several fast food eateries located nearby.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, San Ysidro Transit Center. ATMs are available near the entrance.
Tickets and information
Ticket office support is available at San Diego, San Ysidro Transit Center.
Parking, taxis and toilets
Available at San Diego, San Ysidro Transit Center: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, San Ysidro Transit Center: Wheelchair accessible with ramps.
Which Des Moines, IA station do buses from San Diego, CA arrive at?
Getting to Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) from Des Moines city centre
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) is 3 km from Des Moines city centre. Public transport options include:
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) bus station facilities and services
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.). ATMs are available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.).
Tickets and information
Ticket office support is available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.).
Parking, taxis and toilets
Available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.): Wheelchair accessible buses available.
More options for your journey from San Diego, CA to Des Moines, IA
Here are some other resources that might have the information you need
Most popular buses to and from Des Moines, IA and San Diego, CA
Most popular bus connections to Des Moines, IA
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
