- Must visit
Des Moines Art Center
Major contemporary and modern art museum with a respected collection and notable architecture by Eliel Saarinen, I. M. Pei, and Richard Meier.
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Travel Information
Compare bus and flight for Orlando, FL to Des Moines, IA
Omio recommends booking the flight as it is the most popular option from Orlando, FL to Des Moines, IA among Omio's users. If you are prioritising price take the bus with prices starting from $229. For those with little time consider booking a flight which can get you there in 3h 49m. The ticket price range depends on the travel mode: a bus costs an average of $229, and a flight costs an average of $206.
Distance: 1134 miles (1826 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
$331 Average price Cheapest | $431 Average price | $266 Average price (fuel + tolls) |
33h 40m Average total duration 33h 10m Onboard + 30m Additional time* | 6h 49m Average total duration Fastest 3h 49m Onboard + 3h 0m Additional time* | 19h 48m Average total duration (door-to-door) |
 Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Orlando, FL to Des Moines, IA is a bus with an average price of $331 (€271).
This is compared to other travel options from Orlando, FL to Des Moines, IA:
A bus is $100 (€82) less than a flight for this route with tickets for a flight from Orlando, FL to Des Moines, IA costing on average $431 (€353).
The fastest way to travel from Orlando, FL to Des Moines, IA is by flight with an average journey time of 3h 49m.
Other travel options to Des Moines, IA take longer:
Bus takes on average 33h 10m.
It's helpful to compare your options as there are 2 ways to travel between Orlando, FL and Des Moines, IA including taking a bus and flight.
We recommend using the flight as it is the most popular way to get from Orlando, FL to Des Moines, IA among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Orlando, FL to Des Moines, IA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:55AM | Arrival Time 07:35PM | Duration 40h40 | Departure days Tue, Wed, Thu | Cheapest price $229 |
Operator FlixBus | Departure Time 03:55AM | Arrival Time 08:35PM | Duration 40h40 | Departure days Tue, Wed | Cheapest price $305 |
Operator Greyhound | Departure Time 06:00AM | Arrival Time 06:45PM | Duration 37h45 | Departure days Thu | Cheapest price $197 |
Operator FlixBus | Departure Time 09:00AM | Arrival Time 06:55PM | Duration 34h55 | Departure days Thu | Cheapest price $207 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 12:35AM | Duration 34h35 | Departure days Mon, Tue, Wed, Thu | Cheapest price $163 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 11:45PM | Duration 34h00 | Departure days Thu | Cheapest price $163 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 04:45AM | Duration 34h45 | Departure days Sun | Cheapest price $340 |
Compare prices and tickets Orlando, FL to Des Moines, IA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Orlando, FL to Des Moines, IA buses with Omio?
FlixBus operates all buses services from Orlando, FL to Des Moines, IA.
Omio is an official ticket reseller for all your travel options from Orlando, FL to Des Moines, IA.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Orlando, FL to Des Moines, IA.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Orlando, FL to Des Moines, IA.
Journey information
Overview: Bus from Orlando, FL to Des Moines, IA
USAUSA
Buses from Orlando, FL to Des Moines, IA run on average 2 times per day, taking around 33h 10m. Cheap bus tickets for this journey start at $229 (€187) but you can travel from only $206 (€168) by flight.
The earliest bus runs at 04:00, the last at 23:40. The fastest bus covers the 1134 miles (1826 km) distance in 34h 35m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $206 (€168)
Distance 1134 miles (1826 km) |
Average bus duration 33h 10m |
Cheapest ticket price $229 (€187) |
Buses per day 2 |
Fastest bus 34h 35m |
First bus 4:00 AM |
Last bus 11:40 PM |
Cheapest Month Mar |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jul - Sep |
Best time to book 2 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $206 (€168)
Bus providers: FlixBus from Orlando, FL to Des Moines, IAYou can travel by bus between Orlando, FL to Des Moines, IA with FlixBus for as low as $206 (€168). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
34h 35m
Cheapest Price
$229 (€187)
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Des Moines
Things to do in Des Moines
Discover the best of Des Moines — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Des Moines trip today.
- Recommended
State Historical Museum of Iowa
Museum covering Iowa history through permanent and rotating exhibits, located in the State Historical Building near the Capitol complex.
- Recommended
Salisbury House & Gardens
Historic house museum inspired by English manor architecture, featuring art, books, antiques, and landscaped grounds.
- Must visit
Pappajohn Sculpture Park
Downtown sculpture park featuring major contemporary works in an open urban green space, highly popular for walks and photos.
- Must visit
East Village
Trendy neighborhood east of the river known for independent shops, murals, historic streetscapes, and a lively local atmosphere.
- Must visit
Principal Riverwalk
Signature downtown walking area along the Des Moines River with bridges, lighting, event spaces, and skyline views.
Pork Tenderloin Sandwich
An Iowa classic: a pork cutlet pounded thin, breaded, fried, and served on a bun, often comically larger than the bread. It is one of the state's most iconic comfort foods.
- Vegetarian
- Gluten-free
Sweet Corn
Iowa sweet corn is a summer staple, prized for its tenderness and natural sweetness. It is commonly eaten grilled, boiled, or buttered at fairs, cookouts, and seasonal meals.
Loose Meat Sandwich
A seasoned ground beef sandwich served loose on a bun rather than formed into a patty. It is a longtime Midwestern lunch-counter favorite strongly associated with Iowa.
Aposto at the Scala House
A respected fine-dining venue in a historic house, serving refined American and Italian-influenced dishes in an intimate setting. A strong choice for a special night out.
801 Chophouse
An upscale steakhouse known for classic service, prime steaks, and an elegant atmosphere. It is one of Des Moines' best-known options for a high-end dinner.
Zombie Burger + Drink Lab
A popular Des Moines burger spot known for creative burgers, boozy shakes, and a lively horror-themed atmosphere. A dependable place to try a strong local casual dining favorite.
United States Dollar
Moderate by U.S. standards. Hotels and dining are usually cheaper than in major coastal cities, though downtown and event periods cost more.
Average meal costs
- Budget
- USD 10-15 for fast food or a simple lunch.
- Mid-range
- USD 20-35 per person at a casual sit-down restaurant.
- Fine dining
- USD 60+ per person at upscale restaurants.
- Coffee
- USD 3-6 for drip coffee or a latte.
Tipping culture
Tip 18-20% at restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis 10-15%, hotel staff USD 2-5, and round up for casual services.
FAQs: Bus from Orlando, FL to Des Moines, IA
Find answers to the most common questions about traveling from Orlando, FL to Des Moines, IA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Des Moines, IA, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Orlando, FL to Des Moines, IA can start from as little as $229 (€187) when you book in advance. The average bus ticket price for Orlando, FL to Des Moines, IA is $331 (€271) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Orlando, FL to Des Moines, IA is 34h 35m to travel the 1134 miles (1826 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Orlando, FL to Des Moines, IA leaves at 4:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Orlando, FL to Des Moines, IA leaves at 11:40 PM.
There are 2 buses a day from Orlando, FL to Des Moines, IA which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Orlando, FL to Des Moines, IA, you can count on FlixBus for the best way to get you to Des Moines, IA. You can also check all possible bus companies who offer a service between Orlando, FL and Des Moines, IA and compare the amenities they offer before buying a bus ticket.
A trip to Des Moines, IA from Orlando, FL is worth doing but not as a day trip with a journey time of 34h 35m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Orlando, FL to Des Moines, IA is March.
It's helpful to compare your options as there are 2 ways to travel between Orlando, FL and Des Moines, IA including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Orlando, FL to Des Moines, IA:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Orlando, FL to Des Moines, IA for bus company FlixBus.
Whether you can cancel your bus ticket from Orlando, FL to Des Moines, IA depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Orlando, FL to Des Moines, IA.
Yes, the following luggage options are included when booking a bus ticket from Orlando, FL to Des Moines, IA:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Orlando, FL to Des Moines, IA:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Orlando, FL to Des Moines, IA. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Orlando, FL to Des Moines, IA with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Orlando, FL to Des Moines, IA with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Orlando, FL to Des Moines, IA with the following bus company: FlixBus.
Since neither Orlando, FL nor Des Moines, IA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Orlando, FL to Des Moines, IA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Des Moines, IA, travelers should be cautious of pickpocketing and occasional vehicle break-ins, especially in crowded areas and parking lots. Common scams include fake ticket sellers for local events and unofficial ride services. Staying alert in busy downtown spots and using authorized transportation options helps ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Orlando, FL to Des Moines, IA
Orlando
Des Moines
Orlando, N John Young Pkwy (Greyhound Bus Station)
information
Orlando, The Florida Mall
information
Most popular bus connections from Orlando, FL
More options for your journey from Orlando, FL to Des Moines, IA
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Most popular buses to and from Des Moines, IA and Orlando, FL
Most popular bus connections to Des Moines, IA
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