Orlando, FL to Des Moines, IA bus with FlixBus

Sun, Dec 21
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The cheapest and fastest buses from Orlando, FL to Des Moines, IA

Showing times and prices for Dec 21

Cheapest price

$541

Average price

$584

Fastest journey

1 d 10 h 35 m

Average duration

1 d 11 h 43 m

Buses per day

2

Distance

1826 km

Cheap tickets

The best way to find a cheap bus ticket from Orlando, FL to Des Moines, IA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Orlando, FL to Des Moines, IA will cost around $584 if you buy it on the day, but the cheapest tickets can be found for only $541.

Fast buses

It's difficult to get from Orlando, FL to Des Moines, IA without transferring at least 2 times.

Flixbus USA
12:35PM34h35
Orlando, FL
11:10PMDes Moines, IA
$5411One-way
2 transfers
Greyhound USA
05:15AM36h50
Orlando, FL
06:05PMDes Moines, IA
$6271One-way
2 transfers

Travel Information

Compare bus and flight for Orlando, FL to Des Moines, IA

Omio recommends booking the flight as it is the most popular option from Orlando, FL to Des Moines, IA among Omio's users. If you are prioritising price take the flight with prices starting from €199. For those with little time consider booking a flight which can get you there in 3h 58m. The ticket price range depends on the travel mode: a flight costs an average of €199, and a bus costs an average of €208.

Distance: 1134 miles (1826 km)

Compare bus with

Bus
Most popular
Flight

€208

Average price

€199

Average price

Cheapest

33h 40m

Average total duration

33h 10m

Onboard

+

30m

Additional time*

6h 58m

Average total duration

Fastest

3h 58m

Onboard

+

3h 0m

Additional time*

FlixBus

Most popular bus company

Allegiant Air

Most popular airline

Direct Options

Direct Options

Live departures

Orlando, FL to Des Moines, IA bus times

The table below shows live departures for Orlando, FL to Des Moines, IA buses for today, Saturday, December 20. You can also manually refresh the results below to see updated bus journeys.

Last updated at 10:36 AM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus12:35 PM Orlando, FL
34h35
11:10 PM Des Moines, IA2 transfers
Sunday, December 21
greyhound5:15 AM Orlando, FL
36h50
6:05 PM Des Moines, IA2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Orlando, FL to Des Moines, IA by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
Dec 21
Mon
Dec 22
Tue
Dec 23
Wed
Dec 24
Thu
Dec 25
Fri
Dec 26
Sat
Dec 27

Journey information

Overview: Bus from Orlando, FL to Des Moines, IA

USAUSA
USAUSA
Icon of bus

Buses from Orlando, FL to Des Moines, IA run on average 2 times per day, taking around 33h 10m. Cheap bus tickets for this journey start at $259 (€208) but you can travel from only $248 (€199) by flight.

The earliest bus runs at 04:00, the last at 23:40. The fastest bus covers the 1134 miles (1826 km) distance in 49h 35m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $248 (€199)
Distance
1134 miles (1826 km)
Average bus duration
33h 10m
Cheapest ticket price
$259 (€208)
Buses per day
2
Fastest bus
49h 35m
First bus
04:00
Last bus
23:40
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $248 (€199)

Bus providers: FlixBus, Greyhound from Orlando, FL to Des Moines, IAYou can travel by bus between Orlando, FL to Des Moines, IA with FlixBus, Greyhound for as low as $248 (€199). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
34h 35m
Cheapest Price
$541 (€434)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
49h 35m
Cheapest Price
$259 (€208)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Learn more about Greyhound

FAQs: Bus from Orlando, FL to Des Moines, IA

Find answers to the most common questions about traveling from Orlando, FL to Des Moines, IA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Des Moines, IA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Orlando, FL to Des Moines, IA can start from as little as $612 (€491) when you book in advance. The average bus ticket price for Orlando, FL to Des Moines, IA is $661 (€530); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Orlando, FL to Des Moines, IA bus time is 34 h 35 min   covering the 1132 mile (1825 km) long journey, but the journey time can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from Orlando, FL to Des Moines, IA leaves at 4: 35AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Orlando, FL to Des Moines, IA leaves at 11: 30PM.
There are 2 buses a day from Orlando, FL to Des Moines, IA which require at least one change with FlixBus or Greyhound. Schedules can vary on holidays or weekends with fewer buses.
Take the Orlando, FL to Des Moines, IA bus with FlixBus or Greyhound. However, it's always good to check out all possible bus companies for the route between Orlando, FL and Des Moines, IA as there might be differences in the amenities they offer.
Yes, you can take a bus between Orlando, FL and Des Moines, IA.
Yes, the following accessibility options are available when taking the bus from Orlando, FL to Des Moines, IA:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Orlando, FL to Des Moines, IA for bus companies FlixBus and Greyhound.
Yes, bikes are allowed on board the bus with bus companies FlixBus and Greyhound.
Whether you can cancel your bus ticket from Orlando, FL to Des Moines, IA depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.

To find the cheapest bus tickets for your trip from Orlando, FL to Des Moines, IA, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.

    • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Orlando, FL to Des Moines, IA.
    Yes, the following luggage options are included when booking a bus ticket from Orlando, FL to Des Moines, IA:
    • FlixBus
      • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
    • Greyhound
      • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    Yes, the following additional luggage options are available when booking a bus ticket from Orlando, FL to Des Moines, IA:
    • FlixBus
      • Additional luggage can be purchased for a fee.
    • Greyhound
      • $15 per additional bag.
    Yes, you can bring your pet on the bus from Orlando, FL to Des Moines, IA. The following conditions apply:
    • FlixBus
      • Small pets in carriers allowed
      • Guide dogs travel for free.
    You can reserve your seat on the bus from Orlando, FL to Des Moines, IA with the following bus companies: FlixBus and Greyhound
    Yes, there are USB plugs on board the bus from Orlando, FL to Des Moines, IA with the following bus providers: FlixBus and Greyhound.
    Yes, there is Wifi on board the bus from Orlando, FL to Des Moines, IA with the following bus providers: FlixBus and Greyhound.

    popular bus stations

    Popular bus stations from Orlando, FL to Des Moines, IA

    Orlando
    Des Moines
    Orlando, N John Young Pkwy (Greyhound Bus Station)
    information

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