The cheapest and fastest buses from Orlando, FL to Des Moines, IA
Cheapest price
$531
Average price
$531
Fastest journey
1 d 10 h 35 m
Average duration
1 d 10 h 35 m
Buses per day
1
Distance
1826 km
The best way to find a cheap bus ticket from Orlando, FL to Des Moines, IA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Orlando, FL to Des Moines, IA will cost around $531 if you buy it on the day, but the cheapest tickets can be found for only $531.
It's difficult to get from Orlando, FL to Des Moines, IA without transferring at least 2 times.


Travel Information
Compare bus and flight for Orlando, FL to Des Moines, IA
Omio recommends booking the flight as it is the most popular option from Orlando, FL to Des Moines, IA among Omio's users. If you are prioritising price take the flight with prices starting from €199. For those with little time consider booking a flight which can get you there in 3h 58m. The ticket price range depends on the travel mode: a flight costs an average of €199, and a bus costs an average of €208.
Distance: 1134 miles (1826 km)
Compare bus with
| Bus | Most popular Flight |
|---|---|
€208 Average price | €199 Average price Cheapest |
33h 40m Average total duration 33h 10m Onboard + 30m Additional time* | 6h 58m Average total duration Fastest 3h 58m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
Compare prices and tickets Orlando, FL to Des Moines, IA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Orlando, FL to Des Moines, IA
Distance 1134 miles (1826 km) |
Average bus duration 33h 10m |
Cheapest ticket price $254 (€208) |
Buses per day 2 |
Fastest bus 49h 35m |
First bus 04:00 |
Last bus 23:40 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Orlando, FL to Des Moines, IA start from as low as $254 (€208) if booked well in advance.
- Standard Fares: Typically, trains cost $254 (€208) depending on the train type and class.
Bus providers: FlixBus, Greyhound from Orlando, FL to Des Moines, IAYou can travel by bus between Orlando, FL to Des Moines, IA with FlixBus, Greyhound for as low as $243 (€199). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Orlando, FL to Des Moines, IA

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Orlando, FL to Des Moines, IA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- Additional luggage can be purchased for a fee.
- Greyhound
- $15 per additional bag.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Orlando, FL to Des Moines, IA
Most popular bus connections from Orlando, FL
More options for your journey from Orlando, FL to Des Moines, IA
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