Travel Information
Compare bus and flight for Orlando, FL to Des Moines, IA
Omio recommends booking the flight as it is the most popular option from Orlando, FL to Des Moines, IA among Omio's users. If you are prioritising price take the flight with prices starting from €199. For those with little time consider booking a flight which can get you there in 3h 58m. The ticket price range depends on the travel mode: a flight costs an average of €199, and a bus costs an average of €208.
Distance: 1134 miles (1826 km)
Compare bus with
| Bus | Most popular Flight |
|---|---|
€208 Average price | €199 Average price Cheapest |
33h 40m Average total duration 33h 10m Onboard + 30m Additional time* | 6h 58m Average total duration Fastest 3h 58m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
Compare prices and tickets Orlando, FL to Des Moines, IA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 04
Feb 05
Feb 06
Feb 07
Feb 08
Feb 09
Feb 10
Why should you book Orlando, FL to Des Moines, IA buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Orlando, FL to Des Moines, IA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Orlando, FL to Des Moines, IA.
Why book with Omio over Wanderu?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from Orlando, FL to Des Moines, IA.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Orlando, FL to Des Moines, IA.
Journey information
Overview: Bus from Orlando, FL to Des Moines, IA
Buses from Orlando, FL to Des Moines, IA run on average 2 times per day, taking around 33h 10m. Cheap bus tickets for this journey start at $261 (€208) but you can travel from only $250 (€199) by flight.
The earliest bus runs at 04:00, the last at 23:40. The fastest bus covers the 1134 miles (1826 km) distance in 49h 35m.
Distance 1134 miles (1826 km) |
Average bus duration 33h 10m |
Cheapest ticket price $261 (€208) |
Buses per day 2 |
Fastest bus 49h 35m |
First bus 04:00 |
Last bus 23:40 |
Bus providers: FlixBus, Greyhound from Orlando, FL to Des Moines, IAYou can travel by bus between Orlando, FL to Des Moines, IA with FlixBus, Greyhound for as low as $250 (€199). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Orlando, FL to Des Moines, IA
Find answers to the most common questions about traveling from Orlando, FL to Des Moines, IA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Des Moines, IA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Orlando, FL to Des Moines, IA
Most popular bus connections from Orlando, FL
More options for your journey from Orlando, FL to Des Moines, IA
Here are some other resources that might have the information you need


