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4.6
Travel Information
Compare bus and flight for Orlando, FL to Des Moines, IA
Omio recommends booking the flight as it is the most popular option from Orlando, FL to Des Moines, IA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $269 For those with little time, consider booking a flight, which has an average total journey time of 7h 22m. Average ticket prices depend on the travel mode: a bus costs an average of $269, while a flight costs an average of $538.
Distance: 1134 miles (1826 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
$269 Average price Cheapest | $538 Average price | $271 Average price (fuel + tolls) |
33h 20m Average total duration 32h 50m Onboard + 30m Additional time* | 7h 22m Average total duration Fastest 5h 22m Onboard + 2h 0m Additional time* | 19h 48m Average total duration (door-to-door) |
 Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Orlando, FL to Des Moines, IA:
A bus is $269 less than a flight for this route with tickets for a flight from Orlando, FL to Des Moines, IA costing on average $538.
Other travel options to Des Moines, IA take longer:
Bus takes on average 32h 50m.
Tickets start at around $269 compared to roughly $271 in fuel and tolls — a saving of about $2. The journey takes 32h 50m versus 19h 48m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Orlando, FL to Des Moines, IA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:55AM | Arrival Time 07:35PM | Duration 40h40 | Departure days Tue, Wed, Thu | Cheapest price $229 |
Operator FlixBus | Departure Time 03:55AM | Arrival Time 08:35PM | Duration 40h40 | Departure days Tue, Wed | Cheapest price $306 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 12:35AM | Duration 34h35 | Departure days Mon, Tue, Wed | Cheapest price $348 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 04:45AM | Duration 34h45 | Departure days Thu, Sun | Cheapest price $279 |
Compare prices and tickets Orlando, FL to Des Moines, IA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sep 19
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Sep 25
Why should you book Orlando, FL to Des Moines, IA buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Orlando, FL to Des Moines, IA.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Orlando, FL to Des Moines, IA.
Journey information
Overview: Bus from Orlando, FL to Des Moines, IA
USAUSA
Buses from Orlando, FL to Des Moines, IA run on average 2 times per day, taking around 32h 50m. Cheap bus tickets for this journey start at $249 but you can travel from only $95 by flight.
The earliest bus runs at 04:00, the last at 23:40. The fastest bus covers the 1134 miles (1826 km) distance in 31h 10m.
Distance 1134 miles (1826 km) |
Average bus duration 32h 50m |
Cheapest ticket price $249 |
Buses per day 2 |
Fastest bus 31h 10m |
First bus 4:00 AM |
Last bus 11:40 PM |
Cheapest Month Jun |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jul - Sep |
Best time to book 2 days |
Bus providers: Greyhound, FlixBus from Orlando, FL to Des Moines, IAYou can travel by bus between Orlando, FL to Des Moines, IA with Greyhound, FlixBus for as low as $249. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Orlando, FL to Des Moines, IA
Find answers to the most common questions about traveling from Orlando, FL to Des Moines, IA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Des Moines, IA, this guide helps you travel smarter and with confidence.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Orlando, FL to Des Moines, IA
Most Orlando, FL to Des Moines, IA buses use the Orlando, N John Young Pkwy (Greyhound Bus Station) to Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) station pair. Use this guide to compare Orlando, FL and Des Moines, IA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Orlando, FL station do buses to Des Moines, IA leave from?
Getting to Orlando, N John Young Pkwy (Greyhound Bus Station) from Orlando city centre
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Orlando, N John Young Pkwy (Greyhound Bus Station) bus station facilities and services
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Parking, taxis and toilets
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.
Getting to Orlando, The Florida Mall from Orlando city centre
Which Des Moines, IA station do buses from Orlando, FL arrive at?
Getting to Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) from Des Moines city centre
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) is 3 km from Des Moines city centre. Public transport options include:
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) bus station facilities and services
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.). ATMs are available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.).
Tickets and information
Ticket office support is available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.).
Parking, taxis and toilets
Available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.): Wheelchair accessible buses available.
Most popular bus connections from Orlando, FL
More options for your journey from Orlando, FL to Des Moines, IA
Here are some other resources that might have the information you need
Most popular buses to and from Des Moines, IA and Orlando, FL
Most popular bus connections to Des Moines, IA
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