- Must visit
Des Moines Art Center
Leading art museum with strong American, contemporary, and decorative arts collections, plus a sculpture park just outside downtown.
Buses from Scranton, PA to Des Moines, IA run on average 4 times per day, taking around 28h 32m. Cheap bus tickets for this journey start at $122 if you book in advance.
The earliest bus runs at 05:30, the last at 05:30. The fastest bus covers the 927 miles (1492 km) distance in 22h 50m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Scranton, PA to Des Moines, IA.
Buses from Scranton, PA to Des Moines, IA with Greyhound and FlixBus. Overnight buses available on this route with Greyhound and FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Des Moines, IA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Des Moines, IA trip today.
Leading art museum with strong American, contemporary, and decorative arts collections, plus a sculpture park just outside downtown.
Compact state museum covering Iowa history, culture, and artifacts. A practical stop for visitors wanting context before exploring the city.
Science museum with interactive exhibits, a planetarium, and hands-on displays suited to families and curious adults alike.
A 4.4-acre downtown sculpture park with major contemporary works, open lawns, and easy walking access to nearby restaurants and museums.
Historic neighborhood east of the river with indie shops, murals, nightlife, and restored buildings. Ideal for an easy local walk.
Large urban park with wooded trails, picnic areas, a lake, and river views. A favorite local green escape close to downtown.
Iowa pork tenderloin sandwich features a thin, breaded pork cutlet fried and served on a bun. It is a classic Iowa diner specialty known for its oversized cutlet.
Loose meat sandwich is seasoned ground beef served warm on a bun without being formed into a patty. It is a longtime Iowa lunch-counter staple.
Sweet corn is a signature Iowa summer food, prized for its sweetness and freshness. It is commonly boiled or grilled at fairs, cookouts, and family meals.
Historic market hall with multiple local food vendors, ideal for sampling regional snacks, coffee, craft beer, and casual meals.
Casual local favorite for the classic Iowa breaded pork tenderloin sandwich, plus burgers and comfort food in a laid-back setting.
Long-running smokehouse known for Iowa-style barbecue, ribs, brisket, and hearty sides in a relaxed neighborhood atmosphere.
Moderate for US city breaks; hotels and dining are usually cheaper than larger US metros, while car use can add transport costs.
Tip 15-20% at restaurants, $1-2 per drink at bars, round up or add 10-15% for taxis, and tip a little at cafes only if table service is provided.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Des Moines, IA.
Find answers to the most common questions about traveling from Scranton, PA to Des Moines, IA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Des Moines, IA, this guide helps you travel smarter and with confidence.

Most Scranton, PA to Des Moines, IA buses use the Scranton, Fellows Street / Meridian Avenue to Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) station pair. Use this guide to compare Scranton, PA and Des Moines, IA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Scranton, Fellows Street / Meridian Avenue is 1 km from Scranton city centre. Public transport options include:
Scranton, Fellows Street / Meridian Avenue has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Scranton, Fellows Street / Meridian Avenue. ATMs are available at Scranton, Fellows Street / Meridian Avenue.
Ticket office support is available at Scranton, Fellows Street / Meridian Avenue.
Available at Scranton, Fellows Street / Meridian Avenue: Parking, Taxis, WC.
Accessibility facilities are available at Scranton, Fellows Street / Meridian Avenue: Ramps available for bus boarding.
Scranton, Lackawanna Transit Center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafeteria and vending machines inside.
Free Wi-Fi available throughout the station. ATMs are aTM located near the west entrance.
Ticket office support is available at Scranton, Lackawanna Transit Center.
Available at Scranton, Lackawanna Transit Center: Parking, Taxis, WC.
Accessibility facilities are available at Scranton, Lackawanna Transit Center: Station fully accessible with ramps and elevators.
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) is 3 km from Des Moines city centre. Public transport options include:
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.). ATMs are available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.).
Ticket office support is available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.).
Available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.): Parking, Taxis, WC.
Accessibility facilities are available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.): Wheelchair accessible buses available.
Check bus stations information for Scranton, PA and Des Moines, IA, including where buses depart and arrive on this route.