- Must visit
Des Moines Art Center
Leading art museum with strong American, contemporary, and decorative arts collections, plus a sculpture park just outside downtown.
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The cheapest and fastest buses from Jacksonville, FL to Des Moines, IA
Showing times, prices and bookable tickets for Oct 13
Cheapest price on Oct 13
$307
Average ticket price on Oct 13
$307
Fastest journey on Oct 13
1 d 10 h 25 m
Average journey duration on Oct 13
1 d 10 h 25 m
Buses on Oct 13
1
Distance
1648 km
Cheap tickets
The best way to find a cheap bus ticket from Jacksonville, FL to Des Moines, IA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Jacksonville, FL to Des Moines, IA will cost around $307 if you buy it on the day, but the cheapest tickets can be found for only $307.
Fast buses
On Tue, Oct 13, we found 1 buses from Jacksonville, FL to Des Moines, IA, including 1 direct services.
On Tue, Oct 13 the direct buses cover the 1648 km distance in an average of 1 d 10 h 25 m but if you time it right, some buses will get you there in just 1 d 10 h 25 m .
On Tue, Oct 13 the slowest buses will take 1 d 10 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1:30 PM34h25Jacksonville, FL11:55 PMDes Moines, IA$3071One-way0 transfers
- 1:30 PM34h25Jacksonville, FL11:55 PMDes Moines, IA$3071One-way0 transfers
Journey information
Overview: Bus from Jacksonville, FL to Des Moines, IA
USAUSA
Buses from Jacksonville, FL to Des Moines, IA run on average 2 times per day, taking around 29h 4m. Cheap bus tickets for this journey start at $146 but you can travel from only $92 by flight.
The earliest bus runs at 04:55, the last at 21:25. The fastest bus covers the 1024 miles (1648 km) distance in 25h 16m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $92
Distance 1024 miles (1648 km) |
Average bus duration 29h 4m |
Cheapest ticket price $146 |
Buses per day 2 |
Fastest bus 25h 16m |
First bus 4:55 AM |
Last bus 9:25 PM |
Cheapest Month Jul |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $92
Jacksonville, FL to Des Moines, IA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:25AM | Arrival Time 07:35PM | Duration 42h10 | Departure days Fri | Cheapest price $251 |
Operator Greyhound USA | Departure Time 09:30AM | Arrival Time 06:35PM | Duration 33h05 | Departure days Mon, Wed, Fri, Sun | Cheapest price $304 |
Operator FlixBus | Departure Time 01:30PM | Arrival Time 11:55PM | Duration 34h25 | Departure days Tue | Cheapest price $307 |
Operator FlixBus | Departure Time 08:30PM | Arrival Time 04:45AM | Duration 32h15 | Departure days Thu | Cheapest price $177 |
Operator Flixbus USA | Departure Time 09:25PM | Arrival Time 02:35PM | Duration 41h10 | Departure days Mon, Wed, Sun | Cheapest price $274 |
Live departures
Jacksonville, FL to Des Moines, IA bus times
The table below shows live departures for Jacksonville, FL to Des Moines, IA buses for today, Monday, October 12. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 9:25 PM Jacksonville, FL | 41h10 | 2:35 PM Des Moines, IA | 2 transfers | |
| Tuesday, October 13 | |||||
| 1:30 PM Jacksonville, FL | 34h25 | 11:55 PM Des Moines, IA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Jacksonville, FL to Des Moines, IA buses with Omio?
FlixBus operates all buses services from Jacksonville, FL to Des Moines, IA.
Omio is an official ticket reseller for all your travel options from Jacksonville, FL to Des Moines, IA.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Jacksonville, FL to Des Moines, IA.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Jacksonville, FL to Des Moines, IA.
Bus providers: FlixBus from Jacksonville, FL to Des Moines, IAYou can travel by bus between Jacksonville, FL to Des Moines, IA with FlixBus for as low as $92. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
25h 16m
Cheapest FlixBus Price
$146
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Des Moines, IA
Things to do in Des Moines, IA
Discover the best of Des Moines, IA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Des Moines, IA trip today.
- Recommended
State Historical Museum of Iowa
Compact state museum covering Iowa history, culture, and artifacts. A practical stop for visitors wanting context before exploring the city.
- Recommended
Science Center of Iowa
Science museum with interactive exhibits, a planetarium, and hands-on displays suited to families and curious adults alike.
- Must visit
John and Mary Pappajohn Sculpture Park
A 4.4-acre downtown sculpture park with major contemporary works, open lawns, and easy walking access to nearby restaurants and museums.
- Recommended
East Village
Historic neighborhood east of the river with indie shops, murals, nightlife, and restored buildings. Ideal for an easy local walk.
- Recommended
Gray's Lake Park
Large urban park with wooded trails, picnic areas, a lake, and river views. A favorite local green escape close to downtown.
Pork Tenderloin Sandwich
Iowa pork tenderloin sandwich features a thin, breaded pork cutlet fried and served on a bun. It is a classic Iowa diner specialty known for its oversized cutlet.
Loose Meat Sandwich
Loose meat sandwich is seasoned ground beef served warm on a bun without being formed into a patty. It is a longtime Iowa lunch-counter staple.
- Vegetarian
- Vegan
- Gluten-free
Iowa Sweet Corn
Sweet corn is a signature Iowa summer food, prized for its sweetness and freshness. It is commonly boiled or grilled at fairs, cookouts, and family meals.
Des Moines Downtown Farmers' Market
Historic market hall with multiple local food vendors, ideal for sampling regional snacks, coffee, craft beer, and casual meals.
Smitty's Tenderloin Shop
Casual local favorite for the classic Iowa breaded pork tenderloin sandwich, plus burgers and comfort food in a laid-back setting.
Smokey D's BBQ
Long-running smokehouse known for Iowa-style barbecue, ribs, brisket, and hearty sides in a relaxed neighborhood atmosphere.
US Dollar ($)
Moderate for US city breaks; hotels and dining are usually cheaper than larger US metros, while car use can add transport costs.
Average meal costs
- Budget
- $10-15 for fast food or a casual meal.
- Mid-range
- $20-35 per person for a restaurant meal.
- Fine dining
- $50+ per person for upscale dining.
- Coffee
- $3-6 for coffee or a cappuccino.
Tipping culture
Tip 15-20% at restaurants, $1-2 per drink at bars, round up or add 10-15% for taxis, and tip a little at cafes only if table service is provided.
FAQs: Bus from Jacksonville, FL to Des Moines, IA
Find answers to the most common questions about traveling from Jacksonville, FL to Des Moines, IA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Des Moines, IA, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Jacksonville, FL to Des Moines, IA can start from as little as $146 when you book in advance. The average bus ticket price for Jacksonville, FL to Des Moines, IA is $263 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Jacksonville, FL to Des Moines, IA is 25h 16m to travel the 1024 miles (1648 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Jacksonville, FL to Des Moines, IA leaves at 4:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Jacksonville, FL to Des Moines, IA leaves at 9:25 PM.
There are 2 buses a day from Jacksonville, FL to Des Moines, IA which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Jacksonville, FL to Des Moines, IA, you can count on FlixBus for the best way to get you to Des Moines, IA. You can also check all possible bus companies who offer a service between Jacksonville, FL and Des Moines, IA and compare the amenities they offer before buying a bus ticket.
Passengers board the bus most frequently from Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St, which is located around 0 miles (1 km) away from the city centre, and they get off the bus at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA, located 3 away from the city centre.
It's helpful to compare your options as there are 2 ways to travel between Jacksonville, FL and Des Moines, IA including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Jacksonville, FL to Des Moines, IA:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Jacksonville, FL to Des Moines, IA for bus company FlixBus.
Whether you can cancel your bus ticket from Jacksonville, FL to Des Moines, IA depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Jacksonville, FL to Des Moines, IA.
Yes, the following luggage options are included when booking a bus ticket from Jacksonville, FL to Des Moines, IA:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Jacksonville, FL to Des Moines, IA:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Jacksonville, FL to Des Moines, IA. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Jacksonville, FL to Des Moines, IA with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Jacksonville, FL to Des Moines, IA with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Jacksonville, FL to Des Moines, IA with the following bus company: FlixBus.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Des Moines, IA, travelers should be cautious of pickpocketing and occasional vehicle break-ins, especially in crowded areas and parking lots. Common scams include fake ticket sellers for local events and unofficial ride services. Staying alert in busy downtown spots and using authorized transportation options helps ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Jacksonville, FL to Des Moines, IA
Most Jacksonville, FL to Des Moines, IA buses use the Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St to Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) station pair. Use this guide to compare Jacksonville, FL and Des Moines, IA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Jacksonville
Arrival bus stations in Des Moines
Which Jacksonville, FL station do buses to Des Moines, IA leave from?
Buses from Jacksonville, FL to Des Moines, IA leave from Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St. The station is 1 miles (2 km) from Jacksonville, FL city centre at 1111 W Forsyth St, Jacksonville, FL 32204, USA.
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St1111 W Forsyth St, Jacksonville, FL 32204, USA
City-centre transport
Getting to Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St from Jacksonville city centre
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St is 1 km from Jacksonville city centre. Public transport options include:
Bus1, 11, 18, 205, 3, Nassau, St. Johns, Clay · 12m · $4 · every ~18 min
1, 19, 3 · 17m · $4 · every ~17 min
SubwaySky · 10m · every ~4 min
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St bus station facilities and services
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St. ATMs are available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St.
Tickets and information
Ticket office support is available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St.
Parking, taxis and toilets
Available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St: Wheelchair accessible entrances.
Which Des Moines, IA station do buses from Jacksonville, FL arrive at?
Buses from Jacksonville, FL to Des Moines, IA arrive at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.). Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) is 1 miles (3 km) from Des Moines, IA city centre.
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.)1625 E Euclid Ave, Des Moines, IA 50313, USA
City-centre transport
Getting to Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) from Des Moines city centre
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) is 3 km from Des Moines city centre. Public transport options include:
TRUE
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) bus station facilities and services
Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.). ATMs are available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.).
Tickets and information
Ticket office support is available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.).
Parking, taxis and toilets
Available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.): Wheelchair accessible buses available.
Most popular bus connections from Jacksonville, FL
More options for your journey from Jacksonville, FL to Des Moines, IA
Here are some other resources that might have the information you need
Most popular buses to and from Des Moines, IA and Jacksonville, FL
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