- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
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The cheapest and fastest buses from Harrisburg, PA to Charleston, SC
Showing times, prices and bookable tickets for Sep 19
Cheapest price on Sep 19
€84
Average ticket price on Sep 19
€86
Fastest journey on Sep 19
22 h 20 m
Average journey duration on Sep 19
23 h 52 m
Buses on Sep 19
3
Distance
877 km
Cheap tickets
The best way to find a cheap bus ticket from Harrisburg, PA to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Harrisburg, PA to Charleston, SC will cost around €86 if you buy it on the day, but the cheapest tickets can be found for only €84.
Fast buses
It's difficult to get from Harrisburg, PA to Charleston, SC without transferring at least 2 times.
FlixBus+
· · 5:30 PM25h00Harrisburg, Market St (Bus Station), PA6:30 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC€841One-way4 transfers- +FlixBus+ · 11:20 PM22h20Harrisburg, Market St (Bus Station), PA9:40 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC€841One-way3 transfers
- · · 12:30 PM24h15Harrisburg, Market St (Bus Station), PA12:45 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC€911One-way2 transfers
- +FlixBus+ · 11:20 PM22h20Harrisburg, Market St (Bus Station), PA9:40 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC€841One-way3 transfers
- · · 12:30 PM24h15Harrisburg, Market St (Bus Station), PA12:45 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC€911One-way2 transfers
- FlixBus+ · · 5:30 PM25h00Harrisburg, Market St (Bus Station), PA6:30 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC€841One-way4 transfers
Travel Information
Compare bus, train, and flight for Harrisburg, PA to Charleston, SC
Omio recommends booking the train as it is the most popular option from Harrisburg, PA to Charleston, SC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €122 For those with little time, consider booking a flight, which has an average total journey time of 5h 26m. Average ticket prices depend on the travel mode: a bus costs an average of €122, while a flight costs an average of €472.
Distance: 544 miles (877 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
€122 Average price Cheapest | €211 Average price | €472 Average price | €103 Average price (fuel + tolls) |
20h 11m Average total duration 19h 41m Onboard + 30m Additional time* | 15h 6m Average total duration 14h 36m Onboard + 30m Additional time* | 5h 26m Average total duration Fastest 3h 26m Onboard + 2h 0m Additional time* | 9h 44m Average total duration (door-to-door) |
Most popular bus company |  Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Harrisburg, PA to Charleston, SC is a bus with an average price of €122.
This is compared to other travel options from Harrisburg, PA to Charleston, SC:
A bus is €89 less than a train for this route with tickets for a train from Harrisburg, PA to Charleston, SC costing on average €211.
A bus is €351 less than a flight for this route with tickets for a flight from Harrisburg, PA to Charleston, SC costing on average €472.
The fastest way to travel from Harrisburg, PA to Charleston, SC is by flight with an average journey time of 3h 26m.
Other travel options to Charleston, SC take longer:
Train takes on average 14h 36m.
Bus takes on average 19h 41m.
It's helpful to compare your options as there are 3 ways to travel between Harrisburg, PA and Charleston, SC including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Harrisburg, PA to Charleston, SC among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around €122 compared to roughly €103 in fuel and tolls — a saving of about €-18.56. The journey takes 19h 41m versus 9h 44m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Harrisburg, PA to Charleston, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:30PM | Arrival Time 12:15PM | Duration 23h45 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price €71 |
Operator Greyhound | Departure Time 03:55PM | Arrival Time 06:30PM | Duration 26h35 | Departure days Thu | Cheapest price €75 |
Operator Greyhound | Departure Time 05:30PM | Arrival Time 06:30PM | Duration 25h00 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price €65 |
Operator Greyhound | Departure Time 06:50PM | Arrival Time 10:30PM | Duration 27h40 | Departure days Wed | Cheapest price €200 |
Operator Greyhound | Departure Time 07:50PM | Arrival Time 11:30PM | Duration 27h40 | Departure days Wed | Cheapest price €193 |
Operator Greyhound | Departure Time 11:20PM | Arrival Time 09:40PM | Duration 22h20 | Departure days Mon, Sat | Cheapest price €70 |
Operator Greyhound | Departure Time 11:30PM | Arrival Time 09:50PM | Duration 22h20 | Departure days Tue, Thu, Fri, Sun | Cheapest price €68 |
Live departures
Harrisburg, PA to Charleston, SC bus times
The table below shows live departures for Harrisburg, PA to Charleston, SC buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · · | 12:30 PM Harrisburg, Market St (Bus Station), PA | 23h45 | 12:15 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 2 transfers | |
| FlixBus+ · · | 5:30 PM Harrisburg, Market St (Bus Station), PA | 25h00 | 6:30 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 4 transfers | |
| +FlixBus+ · | 11:30 PM Harrisburg, Market St (Bus Station), PA | 22h20 | 9:50 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Harrisburg, PA to Charleston, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Harrisburg, PA to Charleston, SC buses with Omio?
Greyhound operates all buses services from Harrisburg, PA to Charleston, SC.
Omio is an official ticket reseller for all your travel options from Harrisburg, PA to Charleston, SC.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Harrisburg, PA to Charleston, SC.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Harrisburg, PA to Charleston, SC.
Journey information
Overview: Bus from Harrisburg, PA to Charleston, SC
USAUSA
Buses from Harrisburg, PA to Charleston, SC run on average 3 times per day, taking around 19h 41m. Cheap bus tickets for this journey start at €73 if you book in advance.
The earliest bus runs at 07:45, the last at 23:20. The fastest bus covers the 544 miles (877 km) distance in 17h 35m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 544 miles (877 km) |
Average bus duration 19h 41m |
Cheapest ticket price €73 |
Buses per day 3 |
Fastest bus 17h 35m |
First bus 7:45 AM |
Last bus 11:20 PM |
Cheapest Month Oct |
Cheapest Day Fri |
High Season Jul - Sep |
Low Season Jan - Mar |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound, FlixBus from Harrisburg, PA to Charleston, SCYou can travel by bus between Harrisburg, PA to Charleston, SC with Greyhound, FlixBus for as low as €73. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
17h 45m
Cheapest FlixBus Price
€73
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
17h 35m
Cheapest Greyhound Price
€81
Greyhound frequency
3 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Charleston, SC
Things to do in Charleston, SC
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
- Must visit
Gibbes Museum of Art
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
- Must visit
International African American Museum
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
- Must visit
The Battery
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
- Must visit
East Battery
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
- Must visit
Charleston City Market
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
- Gluten-free
Perloo
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
- Gluten-free
Shrimp And Grits
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
She-Crab Soup
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Circa 1886 Restaurant
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
The Ordinary
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Magnolias
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
US Dollar ($)
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Average meal costs
- Budget
- $10-18 for fast food or casual lunch.
- Mid-range
- $25-45 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale restaurants.
- Coffee
- $4-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
FAQs: Bus from Harrisburg, PA to Charleston, SC
Find answers to the most common questions about traveling from Harrisburg, PA to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Harrisburg, PA to Charleston, SC can start from as little as €73 when you book in advance. The average bus ticket price for Harrisburg, PA to Charleston, SC is €122 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Harrisburg, PA to Charleston, SC is 17h 35m to travel the 544 miles (877 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Harrisburg, PA to Charleston, SC leaves at 7:45 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Harrisburg, PA to Charleston, SC leaves at 11:20 PM.
There are 3 buses a day from Harrisburg, PA to Charleston, SC which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Harrisburg, PA to Charleston, SC, you can count on Greyhound for the best way to get you to Charleston, SC. You can also check all possible bus companies who offer a service between Harrisburg, PA and Charleston, SC and compare the amenities they offer before buying a bus ticket.
When departing from Harrisburg, PA , you have various bus station options to start your journey from including Harrisburg, Market St (Bus Station), PA, Harrisburg, Chestnut Street / South 4th Street, PA . When arriving in Charleston, SC , you can end your journey in bus stations like Charleston, Gaynor Avenue (Greyhound Bus Station), SC .Passengers board the bus most frequently from Harrisburg, Market St (Bus Station), PA, which is located around 0 miles (1 km) away from the city centre, and they get off the bus at Charleston, Gaynor Avenue (Greyhound Bus Station), SC, located 12 away from the city centre.
A trip to Charleston, SC from Harrisburg, PA is worth doing but not as a day trip with a journey time of 17h 35m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Harrisburg, PA to Charleston, SC is October.
It's helpful to compare your options as there are 3 ways to travel between Harrisburg, PA and Charleston, SC including taking a bus, train, and flight.
Yes, there are bathrooms on board the bus from Harrisburg, PA to Charleston, SC for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from Harrisburg, PA to Charleston, SC:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from Harrisburg, PA to Charleston, SC depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Harrisburg, PA to Charleston, SC.
Yes, the following luggage options are included when booking a bus ticket from Harrisburg, PA to Charleston, SC:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Harrisburg, PA to Charleston, SC:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Harrisburg, PA to Charleston, SC.
You can reserve your seat on the bus from Harrisburg, PA to Charleston, SC with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Harrisburg, PA to Charleston, SC with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Harrisburg, PA to Charleston, SC with the following bus company: Greyhound.
Since neither Harrisburg, PA nor Charleston, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Harrisburg, PA to Charleston, SC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Charleston, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like the historic district and popular tourist spots. Beware of overly aggressive street vendors and unofficial taxi services that may overcharge. Additionally, travelers should avoid leaving valuables unattended and be cautious when using ride-sharing apps to ensure the driver matches the booking details. Staying aware of surroundings and using authorized services helps minimize safety risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Harrisburg, PA to Charleston, SC
Most Harrisburg, PA to Charleston, SC buses use the Harrisburg, Market St (Bus Station) to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Harrisburg, PA and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Harrisburg
Arrival bus stations in Charleston
Which Harrisburg, PA station do buses to Charleston, SC leave from?
Buses from Harrisburg, PA to Charleston, SC leave from Harrisburg, Market St (Bus Station). The station is 0 miles (1 km) from Harrisburg, PA city centre at Harrisburg, 411 Market St, Harrisburg, PA 17101, USA.
Harrisburg, Market St (Bus Station)Harrisburg, 411 Market St, Harrisburg, PA 17101, USA
City-centre transport
Getting to Harrisburg, Market St (Bus Station) from Harrisburg city centre
Harrisburg, Market St (Bus Station) is 1 km from Harrisburg city centre. Public transport options include:
Bus6/13, W · 29m · €3 · every ~4 min
Harrisburg, Market St (Bus Station) bus station facilities and services
Harrisburg, Market St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free WiFi inside the station. ATMs are available at Harrisburg, Market St (Bus Station).
Tickets and information
Ticket office support is available at Harrisburg, Market St (Bus Station).
Parking, taxis and toilets
Available at Harrisburg, Market St (Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Harrisburg, Market St (Bus Station): Wheelchair accessible with ramps.
Harrisburg, Chestnut Street / South 4th StreetHarrisburg, 411 Market St, Harrisburg, PA 17101, USA
City-centre transport
Getting to Harrisburg, Chestnut Street / South 4th Street from Harrisburg city centre
Harrisburg, Chestnut Street / South 4th Street is 1 km from Harrisburg city centre. Public transport options include:
Bus2, 7, 81X, A, B, C, D, M, E · 8m · €2 · every ~6 min
2, M, 7, D, A, B, 81X, C, 322, E · 9m · €2 · every ~6 min
Hbg Com Kng B · 15m · €2
Harrisburg, Chestnut Street / South 4th Street bus station facilities and services
Harrisburg, Chestnut Street / South 4th Street has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Harrisburg, Chestnut Street / South 4th Street. ATMs are available at Harrisburg, Chestnut Street / South 4th Street.
Tickets and information
Ticket office support is available at Harrisburg, Chestnut Street / South 4th Street.
Parking, taxis and toilets
Available at Harrisburg, Chestnut Street / South 4th Street: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Harrisburg, Chestnut Street / South 4th Street: Accessible by wheelchair via main entrance.
Which Charleston, SC station do buses from Harrisburg, PA arrive at?
Buses from Harrisburg, PA to Charleston, SC arrive at Charleston, Gaynor Avenue (Greyhound Bus Station). Charleston, Gaynor Avenue (Greyhound Bus Station) is 8 miles (13 km) from Charleston, SC city centre.
Charleston, Gaynor Avenue (Greyhound Bus Station)4565 Gaynor Ave, Charleston, SC 29405, USA
City-centre transport
Getting to Charleston, Gaynor Avenue (Greyhound Bus Station) from Charleston city centre
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Bus10 · 32m · every ~4 min
10 · 41m · every ~4 min
Charleston, Gaynor Avenue (Greyhound Bus Station) bus station facilities and services
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Parking, taxis and toilets
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
Most popular bus connections from Harrisburg, PA
More options for your journey from Harrisburg, PA to Charleston, SC
Here are some other resources that might have the information you need
Most popular buses to and from Charleston, SC and Harrisburg, PA
Most popular bus connections to Charleston, SC
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