- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
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The cheapest and fastest buses from Harrisburg, PA to Charleston, SC
Showing times and prices for Aug 04
Cheapest price
€96
Average price
€97
Fastest journey
22 h
Average duration
23 h 45 m
Buses per day
3
Distance
877 km
Cheap tickets
The best way to find a cheap bus ticket from Harrisburg, PA to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Harrisburg, PA to Charleston, SC will cost around €97 if you buy it on the day, but the cheapest tickets can be found for only €96.
Fast buses
It's difficult to get from Harrisburg, PA to Charleston, SC without transferring at least 2 times.
+
FlixBus+ · 11:40 PM22h00Harrisburg, Market St (Bus Station), PA9:40 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC€961One-way3 transfers- · · 12:30 PM24h15Harrisburg, Market St (Bus Station), PA12:45 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC€971One-way2 transfers
- FlixBus+ · · 5:30 PM25h00Harrisburg, Market St (Bus Station), PA6:30 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC€981One-way4 transfers
- +FlixBus+ · 11:40 PM22h00Harrisburg, Market St (Bus Station), PA9:40 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC€961One-way3 transfers
- · · 12:30 PM24h15Harrisburg, Market St (Bus Station), PA12:45 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC€971One-way2 transfers
- FlixBus+ · · 5:30 PM25h00Harrisburg, Market St (Bus Station), PA6:30 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC€981One-way4 transfers
Journey information
Overview: Bus from Harrisburg, PA to Charleston, SC
USAUSA
Buses from Harrisburg, PA to Charleston, SC run on average 3 times per day, taking around 22h 5m. Cheap bus tickets for this journey start at €82 if you book in advance.
The earliest bus runs at 07:45, the last at 23:20. The fastest bus covers the 544 miles (877 km) distance in 25h 0m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 544 miles (877 km) |
Average bus duration 22h 5m |
Cheapest ticket price €82 |
Buses per day 3 |
Fastest bus 25h 0m |
First bus 7:45 AM |
Last bus 11:20 PM |
Cheapest Month Oct |
Cheapest Day Fri |
High Season Oct - Dec |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Harrisburg, PA to Charleston, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:30PM | Arrival Time 12:45PM | Duration 24h15 | Departure days Everyday | Cheapest price €97 |
Operator Greyhound | Departure Time 04:00PM | Arrival Time 06:30PM | Duration 26h30 | Departure days Thu | Cheapest price €137 |
Operator Greyhound | Departure Time 05:30PM | Arrival Time 06:30PM | Duration 25h00 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price €92 |
Operator Greyhound | Departure Time 09:10PM | Arrival Time 09:40PM | Duration 24h30 | Departure days Mon, Wed, Fri, Sun | Cheapest price €92 |
Operator FlixBus | Departure Time 11:40PM | Arrival Time 12:45PM | Duration 37h05 | Departure days Fri, Sun | Cheapest price €103 |
Operator Greyhound | Departure Time 11:40PM | Arrival Time 09:40PM | Duration 22h00 | Departure days Mon, Tue, Wed, Thu, Sat | Cheapest price €94 |
Operator Greyhound | Departure Time 11:50PM | Arrival Time 09:50PM | Duration 22h00 | Departure days Sun | Cheapest price €95 |
Live departures
Harrisburg, PA to Charleston, SC bus times
The table below shows live departures for Harrisburg, PA to Charleston, SC buses for today, Monday, August 3. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · · | 9:10 PM Harrisburg, Market St (Bus Station), PA | 24h30 | 9:40 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 2 transfers | |
| +FlixBus · FlixBus+ | 11:40 PM Harrisburg, Market St (Bus Station), PA | 37h05 | 12:45 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 4 transfers | |
| Tuesday, August 4 | |||||
| · · | 12:30 PM Harrisburg, Market St (Bus Station), PA | 24h15 | 12:45 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 2 transfers | |
| FlixBus+ · · | 5:30 PM Harrisburg, Market St (Bus Station), PA | 25h00 | 6:30 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 4 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Harrisburg, PA to Charleston, SC buses with Omio?
Greyhound operates all buses services from Harrisburg, PA to Charleston, SC.
Omio is an official ticket reseller for all your travel options from Harrisburg, PA to Charleston, SC.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Harrisburg, PA to Charleston, SC.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Harrisburg, PA to Charleston, SC.
Bus providers: Greyhound from Harrisburg, PA to Charleston, SCYou can travel by bus between Harrisburg, PA to Charleston, SC with Greyhound for as low as €82. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
25h 0m
Cheapest Price
€82
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Charleston, SC
Things to do in Charleston, SC
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
- Must visit
Gibbes Museum of Art
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
- Must visit
International African American Museum
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
- Must visit
The Battery
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
- Must visit
East Battery
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
- Must visit
Charleston City Market
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
- Gluten-free
Perloo
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
- Gluten-free
Shrimp And Grits
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
She-Crab Soup
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Circa 1886 Restaurant
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
The Ordinary
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Magnolias
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
US Dollar ($)
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Average meal costs
- Budget
- $10-18 for fast food or casual lunch.
- Mid-range
- $25-45 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale restaurants.
- Coffee
- $4-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
FAQs: Bus from Harrisburg, PA to Charleston, SC
Find answers to the most common questions about traveling from Harrisburg, PA to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Harrisburg, PA to Charleston, SC can start from as little as €82 when you book in advance. The average bus ticket price for Harrisburg, PA to Charleston, SC is €164 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Harrisburg, PA to Charleston, SC is 25h 0m to travel the 544 miles (877 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Harrisburg, PA to Charleston, SC leaves at 7:45 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Harrisburg, PA to Charleston, SC leaves at 11:20 PM.
There are 3 buses a day from Harrisburg, PA to Charleston, SC which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Harrisburg, PA to Charleston, SC, you can count on Greyhound for the best way to get you to Charleston, SC. You can also check all possible bus companies who offer a service between Harrisburg, PA and Charleston, SC and compare the amenities they offer before buying a bus ticket.
It's helpful to compare your options as there are 3 ways to travel between Harrisburg, PA and Charleston, SC including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Harrisburg, PA to Charleston, SC:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Harrisburg, PA to Charleston, SC for bus company Greyhound.
Whether you can cancel your bus ticket from Harrisburg, PA to Charleston, SC depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Harrisburg, PA to Charleston, SC.
Yes, the following luggage options are included when booking a bus ticket from Harrisburg, PA to Charleston, SC:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Harrisburg, PA to Charleston, SC:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Harrisburg, PA to Charleston, SC.
You can reserve your seat on the bus from Harrisburg, PA to Charleston, SC with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Harrisburg, PA to Charleston, SC with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Harrisburg, PA to Charleston, SC with the following bus company: Greyhound.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Charleston, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like the historic district and popular tourist spots. Beware of overly aggressive street vendors and unofficial taxi services that may overcharge. Additionally, travelers should avoid leaving valuables unattended and be cautious when using ride-sharing apps to ensure the driver matches the booking details. Staying aware of surroundings and using authorized services helps minimize safety risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Harrisburg, PA to Charleston, SC
Most Harrisburg, PA to Charleston, SC buses use the Harrisburg, Market St (Bus Station) to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Harrisburg, PA and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Harrisburg
Arrival bus stations in Charleston
Harrisburg, Market St (Bus Station)
City-centre transport
Getting to Harrisburg, Market St (Bus Station) from Harrisburg city centre
Bus6/13, W · 29m · €3 · every ~4 min
Harrisburg, Chestnut Street / South 4th Street
City-centre transport
Getting to Harrisburg, Chestnut Street / South 4th Street from Harrisburg city centre
Bus2, 7, 81X, A, B, C, D, M, E · 8m · €2 · every ~6 min
2, M, 7, D, A, B, 81X, C, 322, E · 9m · €2 · every ~6 min
Hbg Com Kng B · 15m · €2
Charleston, Gaynor Avenue (Greyhound Bus Station)
City-centre transport
Getting to Charleston, Gaynor Avenue (Greyhound Bus Station) from Charleston city centre
Bus10 · 32m · every ~4 min
10 · 41m · every ~4 min
Most popular bus connections from Harrisburg, PA
More options for your journey from Harrisburg, PA to Charleston, SC
Here are some other resources that might have the information you need
Most popular buses to and from Charleston, SC and Harrisburg, PA
Most popular bus connections to Charleston, SC
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