- Must visit
The Charleston Museum
Often called America's first museum, it covers Charleston and Lowcountry history, decorative arts, natural history, and regional culture.
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The cheapest and fastest buses from Harrisburg, PA to Charleston, SC
Showing times and prices for Jun 20
Cheapest price
$219
Average price
$219
Fastest journey
1 d 3 h 40 m
Average duration
1 d 3 h 40 m
Buses per day
1
Distance
877 km
Cheap tickets
The best way to find a cheap bus ticket from Harrisburg, PA to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Harrisburg, PA to Charleston, SC will cost around $219 if you buy it on the day, but the cheapest tickets can be found for only $219.
Fast buses
Of the 1 buses that leave Harrisburg, PA for Charleston, SC on Sat, Jun 20, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 20 the direct buses cover the 877 km distance in an average of 1 d 3 h 40 m but if you time it right, some buses will get you there in just 1 d 3 h 40 m .
On Sat, Jun 20 the slowest buses will take 1 d 3 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
7:50 PM27h40Harrisburg, PA11:30 PMCharleston, SC$2191One-way0 transfers
- 7:50 PM27h40Harrisburg, PA11:30 PMCharleston, SC$2191One-way0 transfers
Travel Information
Compare bus, train, and flight for Harrisburg, PA to Charleston, SC
Omio recommends booking the train as it is the most popular option from Harrisburg, PA to Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from $101. For those with little time consider booking a flight which can get you there in 6h 29m. The ticket price range depends on the travel mode: a bus costs an average of $101, and a flight costs an average of $141.
Distance: 544 miles (877 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$200 Average price Cheapest | $249 Average price | $385 Average price | $124 Average price (fuel + tolls) |
22h 35m Average total duration 22h 5m Onboard + 30m Additional time* | 15h 2m Average total duration 14h 32m Onboard + 30m Additional time* | 9h 29m Average total duration Fastest 6h 29m Onboard + 3h 0m Additional time* | 9h 44m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Harrisburg, PA to Charleston, SC is a bus with an average price of $200 (€164).
This is compared to other travel options from Harrisburg, PA to Charleston, SC:
A bus is $49 (€40) less than a train for this route with tickets for a train from Harrisburg, PA to Charleston, SC costing on average $249 (€204).
A bus is $185 (€152) less than a flight for this route with tickets for a flight from Harrisburg, PA to Charleston, SC costing on average $385 (€316).
The fastest way to travel from Harrisburg, PA to Charleston, SC is by flight with an average journey time of 6h 29m.
Other travel options to Charleston, SC take longer:
Train takes on average 14h 32m.
Bus takes on average 22h 5m.
It's helpful to compare your options as there are 3 ways to travel between Harrisburg, PA and Charleston, SC including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Harrisburg, PA to Charleston, SC among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Harrisburg, PA to Charleston, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 05:30PM | Arrival Time 06:30PM | Duration 25h00 | Departure days Fri, Sun | Cheapest price $130 |
Operator Greyhound | Departure Time 06:50PM | Arrival Time 10:30PM | Duration 27h40 | Departure days Mon, Tue, Wed, Thu | Cheapest price $161 |
Operator Greyhound | Departure Time 07:50PM | Arrival Time 11:30PM | Duration 27h40 | Departure days Wed, Sat | Cheapest price $219 |
Live departures
Harrisburg, PA to Charleston, SC bus times
The table below shows live departures for Harrisburg, PA to Charleston, SC buses for today, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 FlixBus · FlixBus+ · | 5:30 PM Harrisburg, Market St (Bus Station), PA | 25h00 | 6:30 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 4 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Harrisburg, PA to Charleston, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Harrisburg, PA to Charleston, SC buses with Omio?
Greyhound operates all buses services from Harrisburg, PA to Charleston, SC.
Omio is an official ticket reseller for all your travel options from Harrisburg, PA to Charleston, SC.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Harrisburg, PA to Charleston, SC.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Harrisburg, PA to Charleston, SC.
Journey information
Overview: Bus from Harrisburg, PA to Charleston, SC
USAUSA
Buses from Harrisburg, PA to Charleston, SC run on average 3 times per day, taking around 22h 5m. Cheap bus tickets for this journey start at $101 (€82) if you book in advance.
The earliest bus runs at 07:45, the last at 23:20. The fastest bus covers the 544 miles (877 km) distance in 25h 0m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 544 miles (877 km) |
Average bus duration 22h 5m |
Cheapest ticket price $101 (€82) |
Buses per day 3 |
Fastest bus 25h 0m |
First bus 7:45 AM |
Last bus 11:20 PM |
Cheapest Month Oct |
Cheapest Day Fri |
High Season Oct - Dec |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from Harrisburg, PA to Charleston, SCYou can travel by bus between Harrisburg, PA to Charleston, SC with Greyhound for as low as $101 (€82). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
25h 0m
Cheapest Price
$101 (€82)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Charleston
Things to do in Charleston
Discover the best of Charleston — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston trip today.
- Must visit
Old Slave Mart Museum
A small but important museum interpreting the domestic slave trade in Charleston through exhibits in a historic market building.
- Must visit
Gibbes Museum of Art
Charleston's leading art museum, known for American art with strong ties to the South, rotating exhibitions, and a distinguished permanent collection.
- Must visit
The Battery
Charleston's famous waterfront promenade is lined with grand historic homes, harbor views, and classic postcard scenery.
- Must visit
Waterfront Park
A popular riverfront park known for its pier, lawns, and the photogenic Pineapple Fountain.
- Must visit
King Street
Charleston's best-known commercial corridor, mixing historic architecture, shopping, nightlife, and frequent social media visibility.
- Gluten-free
Shrimp And Grits
A Lowcountry classic of sautéed shrimp served over creamy grits, often with bacon or gravy. It is one of Charleston’s signature dishes.
- Gluten-free
She-Crab Soup
A rich Charleston soup made with crab meat, crab roe, cream, and sherry. It is a historic local specialty associated with the city’s coastal cuisine.
- Gluten-free
Hoppin’ John
A traditional rice and field pea dish, usually cooked with pork for flavor. It is an iconic Southern and Lowcountry comfort food.
FIG
One of Charleston’s most acclaimed restaurants, serving ingredient-driven Southern cuisine with a polished but approachable feel. Reservations are highly sought after.
Fleet Landing Restaurant & Bar
A popular waterfront restaurant known for Lowcountry seafood, shrimp and grits, and relaxed harbor views. It is a dependable choice for classic Charleston flavors.
Husk
A celebrated restaurant focused on refined Southern cooking using seasonal local ingredients. Stylish and upscale, it is one of Charleston’s best-known dining rooms.
United States Dollar
Prices are moderate by U.S. standards. Historic district dining and hotels cost more, while casual food and transport stay manageable.
Average meal costs
- Budget
- USD 10-18 for casual spots or takeout.
- Mid-range
- USD 25-45 per person at a mid-range restaurant.
- Fine dining
- USD 75-150+ per person at upscale restaurants.
- Coffee
- USD 4-7 for coffee or a latte.
Tipping culture
Tip 18-20% in restaurants. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and valet. Tipping is expected for most service roles.
FAQs: Bus from Harrisburg, PA to Charleston, SC
Find answers to the most common questions about traveling from Harrisburg, PA to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Harrisburg, PA to Charleston, SC can start from as little as $101 (€82) when you book in advance. The average bus ticket price for Harrisburg, PA to Charleston, SC is $200 (€164) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Harrisburg, PA to Charleston, SC is 25h 0m to travel the 544 miles (877 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Harrisburg, PA to Charleston, SC leaves at 7:45 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Harrisburg, PA to Charleston, SC leaves at 11:20 PM.
There are 3 buses a day from Harrisburg, PA to Charleston, SC which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Harrisburg, PA to Charleston, SC, you can count on Greyhound for the best way to get you to Charleston, SC. You can also check all possible bus companies who offer a service between Harrisburg, PA and Charleston, SC and compare the amenities they offer before buying a bus ticket.
A trip to Charleston, SC from Harrisburg, PA is worth doing but not as a day trip with a journey time of 25h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Harrisburg, PA to Charleston, SC is October.
It's helpful to compare your options as there are 3 ways to travel between Harrisburg, PA and Charleston, SC including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Harrisburg, PA to Charleston, SC:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Harrisburg, PA to Charleston, SC for bus company Greyhound.
Whether you can cancel your bus ticket from Harrisburg, PA to Charleston, SC depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Harrisburg, PA to Charleston, SC.
Yes, the following luggage options are included when booking a bus ticket from Harrisburg, PA to Charleston, SC:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Harrisburg, PA to Charleston, SC:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Harrisburg, PA to Charleston, SC.
You can reserve your seat on the bus from Harrisburg, PA to Charleston, SC with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Harrisburg, PA to Charleston, SC with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Harrisburg, PA to Charleston, SC with the following bus company: Greyhound.
Since neither Harrisburg, PA nor Charleston, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Harrisburg, PA to Charleston, SC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Charleston, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like the historic district and popular tourist spots. Beware of overly aggressive street vendors and unofficial taxi services that may overcharge. Additionally, travelers should avoid leaving valuables unattended and be cautious when using ride-sharing apps to ensure the driver matches the booking details. Staying aware of surroundings and using authorized services helps minimize safety risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Harrisburg, PA to Charleston, SC
Harrisburg
Charleston
The major bus station for departures in Harrisburg is Harrisburg, Market St (Bus Station). Find all the information you need to know about services, amenities and connections at Harrisburg, Market St (Bus Station) for your trip from Harrisburg to Charleston.
Harrisburg, Market St (Bus Station)
information
Harrisburg, Chestnut Street / South 4th Street
information
The major bus station for arrivals in Charleston is Charleston, Gaynor Avenue (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Charleston, Gaynor Avenue (Greyhound Bus Station) for your trip to Charleston from Harrisburg.
Charleston, Gaynor Avenue (Greyhound Bus Station)
information
Most popular bus connections from Harrisburg, PA
More options for your journey from Harrisburg, PA to Charleston, SC
Here are some other resources that might have the information you need
Most popular buses to and from Charleston, SC and Harrisburg, PA
Most popular bus connections to Charleston, SC
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