The cheapest and fastest buses from Harrisburg, PA to Charleston, SC
Cheapest price
$161
Average price
$161
Fastest journey
1 d
Average duration
1 d
Buses per day
1
Distance
877 km
The best way to find a cheap bus ticket from Harrisburg, PA to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Harrisburg, PA to Charleston, SC will cost around $161 if you buy it on the day, but the cheapest tickets can be found for only $161.
Of the 1 buses that leave Harrisburg, PA for Charleston, SC on Thu, Feb 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Feb 05 the direct buses cover the 877 km distance in an average of 1 d but if you time it right, some buses will get you there in just 1 d .
On Thu, Feb 05 the slowest buses will take 1 d and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for Harrisburg, PA to Charleston, SC
Omio recommends booking the train as it is the most popular option from Harrisburg, PA to Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from €68. For those with little time consider booking a flight which can get you there in 5h 33m. The ticket price range depends on the travel mode: a bus costs an average of €68, and a flight costs an average of €161.
Distance: 544 miles (877 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€120 Average price Cheapest | €172 Average price | €284 Average price |
25h 0m Average total duration 24h 30m Onboard + 30m Additional time* | 14h 32m Average total duration 14h 2m Onboard + 30m Additional time* | 8h 33m Average total duration Fastest 5h 33m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Harrisburg, PA to Charleston, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 05
Feb 06
Feb 07
Feb 08
Feb 09
Feb 10
Feb 11
Journey information
Overview: Bus from Harrisburg, PA to Charleston, SC
Buses from Harrisburg, PA to Charleston, SC run on average 4 times per day, taking around 24h 30m. Cheap bus tickets for this journey start at $86 (€68) if you book in advance.
The earliest bus runs at 07:45, the last at 21:34. The fastest bus covers the 544 miles (877 km) distance in 24h 0m.
Distance 544 miles (877 km) |
Average bus duration 24h 30m |
Cheapest ticket price $86 (€68) |
Buses per day 4 |
Fastest bus 24h 0m |
First bus 07:45 |
Last bus 21:34 |
FAQs: Bus from Harrisburg, PA to Charleston, SC
Find answers to the most common questions about traveling from Harrisburg, PA to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from Harrisburg, PA to Charleston, SC
Most popular bus connections from Harrisburg, PA
More options for your journey from Harrisburg, PA to Charleston, SC
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