- Must visit
The Charleston Museum
Often called America’s first museum, it covers Charleston and Lowcountry history through archaeology, decorative arts, and natural history collections.
Cheapest price
$162
Average price
$163
Fastest journey
13 h 45 m
Average duration
13 h 45 m
Buses per day
2
Distance
491 km
The best way to find a cheap bus ticket from Orlando, FL to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Orlando, FL to Charleston, SC will cost around $163 if you buy it on the day, but the cheapest tickets can be found for only $162.
Of the 2 buses that leave Orlando, FL for Charleston, SC on Sat, Jul 11, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jul 11 the direct buses cover the 491 km distance in an average of 13 h 45 m but if you time it right, some buses will get you there in just 13 h 45 m .
On Sat, Jul 11 the slowest buses will take 13 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the train as it is the most popular option from Orlando, FL to Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from $54. For those with little time consider booking a flight which can get you there in 2h 12m. The ticket price range depends on the travel mode: a bus costs an average of $54, and a flight costs an average of $41.
Distance: 305 miles (491 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$128 Average price Cheapest | $134 Average price | $233 Average price | $76 Average price (fuel + tolls) |
10h 50m Average total duration 10h 20m Onboard + 30m Additional time* | 8h 17m Average total duration 7h 47m Onboard + 30m Additional time* | 5h 12m Average total duration Fastest 2h 12m Onboard + 3h 0m Additional time* | 5h 43m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Orlando, FL to Charleston, SC:
A bus is $6 (€5) less than a train for this route with tickets for a train from Orlando, FL to Charleston, SC costing on average $134 (€110).
A bus is $105 (€86) less than a flight for this route with tickets for a flight from Orlando, FL to Charleston, SC costing on average $233 (€191).
Other travel options to Charleston, SC take longer:
Train takes on average 7h 47m.
Bus takes on average 10h 20m.
You'll arrive about -5h -37m sooner (10h 20m by bus vs 5h 43m by car) and save roughly $-51.60 (€-42.42) compared to fuel and tolls ($128 (€105) vs $76 (€62)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by FlixBus.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 08:00AM | Arrival Time 10:30PM | Duration 14h30 | Departure days Tue, Wed | Cheapest price $109 |
Operator FlixBus | Departure Time 08:45AM | Arrival Time 10:30PM | Duration 13h45 | Departure days Everyday | Cheapest price $129 |
Operator FlixBus | Departure Time 09:00AM | Arrival Time 11:30PM | Duration 14h30 | Departure days Tue, Wed | Cheapest price $54 |
Operator FlixBus | Departure Time 09:45AM | Arrival Time 11:30PM | Duration 13h45 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $77 |
The table below shows live departures for Orlando, FL to Charleston, SC buses for tomorrow, Saturday, July 11. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:45 AM Orlando, FL | 13h45 | 10:30 PM Charleston, SC | 0 transfersDirect | |
![]() | 9:45 AM Orlando, FL | 13h45 | 11:30 PM Charleston, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Orlando, FL to Charleston, SC run on average 1 times per day, taking around 10h 20m. Cheap bus tickets for this journey start at $54 (€44) but you can travel from only $41 (€34) by flight.
The earliest bus runs at 04:00, the last at 23:40. The fastest bus covers the 305 miles (491 km) distance in 13h 45m.
Distance 305 miles (491 km) |
Average bus duration 10h 20m |
Cheapest ticket price $54 (€44) |
Buses per day 1 |
Fastest bus 13h 45m |
First bus 4:00 AM |
Last bus 11:40 PM |
Cheapest Month Mar |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Apr - Jun |
Busiest Day Wed |
Least Busy Day Fri |
Best time to book 28 days |
Discover the best of Charleston — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston trip today.
Often called America’s first museum, it covers Charleston and Lowcountry history through archaeology, decorative arts, and natural history collections.
Charleston’s leading art museum, known for American works with strong connections to the city, the South, and regional artists.
A major new museum on the waterfront exploring African American history and the African diaspora through immersive exhibitions.
Charleston’s signature waterfront promenade, lined with historic mansions, harbor views, and one of the city’s classic walks.
A popular harborfront park known for pier views, shaded paths, and the famous Pineapple Fountain.
One of Charleston’s best-known streets for architecture, shopping, and lively city atmosphere across several distinct sections.
A Lowcountry classic of shrimp served over creamy stone-ground grits, often with bacon, gravy, or sausage. It is one of Charleston’s signature comfort dishes.
A rich coastal soup made with crab meat, crab roe, cream, and a splash of sherry. It is strongly associated with Charleston and historic Lowcountry dining.
A traditional rice and field pea dish, usually seasoned with pork. It is a classic Southern and Lowcountry staple, especially around New Year celebrations.
One of Charleston’s best-known fine dining restaurants, serving polished Southern dishes with strong local sourcing in an elegant but relaxed atmosphere.
A celebrated Southern restaurant known for refined Lowcountry cooking, seasonal local ingredients, and a historic Charleston setting.
A popular waterfront venue set in a former naval building, known for seafood, she-crab soup, and harbor views.
Moderate by U.S. standards. Hotels and fine dining can be pricey, but casual dining and coffee are fairly typical for a popular coastal city.
Tip 18-20% at restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis and rideshares 10-15%, hotel staff USD 2-5, and round up for casual services.
Find answers to the most common questions about traveling from Orlando, FL to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

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