- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Cheapest price on Oct 10
€134
Average ticket price on Oct 10
€134
Fastest journey on Oct 10
13 h 45 m
Average journey duration on Oct 10
13 h 45 m
Buses on Oct 10
2
Distance
491 km
The best way to find a cheap bus ticket from Orlando, FL to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Orlando, FL to Charleston, SC will cost around €134 if you buy it on the day, but the cheapest tickets can be found for only €134.
On Sat, Oct 10, we found 2 buses from Orlando, FL to Charleston, SC, including 2 direct services.
On Sat, Oct 10 the direct buses cover the 491 km distance in an average of 13 h 45 m but if you time it right, some buses will get you there in just 13 h 45 m .
On Sat, Oct 10 the slowest buses will take 13 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Buses from Orlando, FL to Charleston, SC run on average 1 times per day, taking around 11h 51m. Cheap bus tickets for this journey start at €43 but you can travel from only €42 by flight.
The earliest bus runs at 04:00, the last at 23:40. The fastest bus covers the 305 miles (491 km) distance in 7h 20m.
Distance 305 miles (491 km) |
Average bus duration 11h 51m |
Cheapest ticket price €43 |
Buses per day 1 |
Fastest bus 7h 20m |
First bus 4:00 AM |
Last bus 11:40 PM |
Cheapest Month Jul |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Wed |
Least Busy Day Sun |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 06:00AM | Arrival Time 02:55PM | Duration 8h55 | Departure days Tue, Wed, Fri | Cheapest price €50 |
Operator FlixBus | Departure Time 08:45AM | Arrival Time 10:30PM | Duration 13h45 | Departure days Mon, Thu, Sat, Sun | Cheapest price €106 |
Operator FlixBus | Departure Time 09:45AM | Arrival Time 11:30PM | Duration 13h45 | Departure days Mon, Thu, Sat, Sun | Cheapest price €63 |
The table below shows live departures for Orlando, FL to Charleston, SC buses for today, Friday, October 9. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+![]() | 6:00 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 8h55 | 2:55 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
Find answers to the most common questions about traveling from Orlando, FL to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

Most Orlando, FL to Charleston, SC buses use the Orlando, N John Young Pkwy (Greyhound Bus Station) to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Orlando, FL and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
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