- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Cheapest price
CHF44
Average price
CHF84
Fastest journey
13 h 45 m
Average duration
14 h 15 m
Buses per day
3
Distance
491 km
The best way to find a cheap bus ticket from Orlando, FL to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Orlando, FL to Charleston, SC will cost around CHF84 if you buy it on the day, but the cheapest tickets can be found for only CHF44.
Of the 3 buses that leave Orlando, FL for Charleston, SC on Wed, Aug 26, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Aug 26 the direct buses cover the 491 km distance in an average of 14 h 15 m but if you time it right, some buses will get you there in just 13 h 45 m .
On Wed, Aug 26 the slowest buses will take 14 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Omio recommends booking the train as it is the most popular option from Orlando, FL to Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from CHF37. For those with little time consider booking a flight which can get you there in 2h 13m. The ticket price range depends on the travel mode: a bus costs an average of CHF37, and a flight costs an average of CHF48.
Distance: 305 miles (491 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
CHF59 Average price Cheapest | CHF88 Average price | CHF128 Average price | CHF63 Average price (fuel + tolls) |
10h 50m Average total duration 10h 20m Onboard + 30m Additional time* | 8h 17m Average total duration 7h 47m Onboard + 30m Additional time* | 5h 13m Average total duration Fastest 2h 13m Onboard + 3h 0m Additional time* | 5h 43m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Orlando, FL to Charleston, SC:
A bus is CHF29 less than a train for this route with tickets for a train from Orlando, FL to Charleston, SC costing on average CHF88.
A bus is CHF69 less than a flight for this route with tickets for a flight from Orlando, FL to Charleston, SC costing on average CHF128.
Other travel options to Charleston, SC take longer:
Train takes on average 7h 47m.
Bus takes on average 10h 20m.
Tickets start at around CHF59 compared to roughly CHF63 in fuel and tolls — a saving of about CHF4. The journey takes 10h 20m versus 5h 43m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:45AM | Arrival Time 06:30PM | Duration 13h45 | Departure days Mon, Thu, Sun | Cheapest price CHF40 |
Operator FlixBus | Departure Time 08:00AM | Arrival Time 10:30PM | Duration 14h30 | Departure days Tue, Wed | Cheapest price CHF89 |
Operator FlixBus | Departure Time 08:45AM | Arrival Time 10:30PM | Duration 13h45 | Departure days Tue, Wed, Fri, Sat | Cheapest price CHF119 |
Operator FlixBus | Departure Time 09:00AM | Arrival Time 11:30PM | Duration 14h30 | Departure days Tue, Wed | Cheapest price CHF44 |
Operator FlixBus | Departure Time 09:45AM | Arrival Time 11:30PM | Duration 13h45 | Departure days Fri, Sat | Cheapest price CHF130 |
The table below shows live departures for Orlando, FL to Charleston, SC buses for today, Tuesday, August 25. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:00 AM Orlando, FL | 14h30 | 10:30 PM Charleston, SC | 0 transfersDirect | |
![]() | 8:45 AM Orlando, FL | 13h45 | 10:30 PM Charleston, SC | 0 transfersDirect | |
![]() | 9:00 AM Orlando, FL | 14h30 | 11:30 PM Charleston, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Orlando, FL to Charleston, SC run on average 1 times per day, taking around 10h 20m. Cheap bus tickets for this journey start at CHF37 if you book in advance.
The earliest bus runs at 04:00, the last at 23:40. The fastest bus covers the 305 miles (491 km) distance in 9h 50m.
Distance 305 miles (491 km) |
Average bus duration 10h 20m |
Cheapest ticket price CHF37 |
Buses per day 1 |
Fastest bus 9h 50m |
First bus 4:00 AM |
Last bus 11:40 PM |
Cheapest Month Jul |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Wed |
Least Busy Day Tue |
Best time to book 28 days |
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
Find answers to the most common questions about traveling from Orlando, FL to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

Most Orlando, FL to Charleston, SC buses use the Orlando, N John Young Pkwy (Greyhound Bus Station) to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Orlando, FL and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
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