Orlando, FL to Charleston, SC bus with Greyhound

Fri, Nov 21
+ Add return
Greyhound
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
Greyhound
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

The cheapest and fastest buses from Orlando, FL to Charleston, SC

Showing times and prices for Nov 22

Cheapest price

$112

Average price

$112

Fastest journey

13 h 45 m

Average duration

13 h 45 m

Buses per day

1

Distance

491 km

Cheap tickets

The best way to find a cheap bus ticket from Orlando, FL to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Orlando, FL to Charleston, SC will cost around $112 if you buy it on the day, but the cheapest tickets can be found for only $112.

Fast buses

It's difficult to get from Orlando, FL to Charleston, SC without transferring at least 2 times.

FlixBusFlixBus · FlixBus+Greyhound
04:45AM13h45
Orlando, N John Young Pkwy (Greyhound Bus Station)
06:30PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC
$1121One-way
2 transfers

Travel Information

Compare bus, train, and flight for Orlando, FL to Charleston, SC

Omio recommends booking the train as it is the most popular option from Orlando, FL to Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from €36. For those with little time consider booking a flight which can get you there in 2h 21m. The ticket price range depends on the travel mode: a bus costs an average of €36, and a flight costs an average of €39.

Distance: 305 miles (491 km)

Compare bus with

Bus
Most popular
Train
Flight

€55

Average price

Cheapest

€85

Average price

€186

Average price

8h 35m

Average total duration

8h 5m

Onboard

+

30m

Additional time*

8h 19m

Average total duration

7h 49m

Onboard

+

30m

Additional time*

5h 21m

Average total duration

Fastest

2h 21m

Onboard

+

3h 0m

Additional time*

Greyhound

Most popular bus company

Amtrak

Most popular train company

Breeze Airways

Most popular airline

Direct Options

Direct Options

Direct Options

Orlando, FL to Charleston, SC Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
04:45AM
Arrival Time
06:30PM
Duration
13h45
Departure days
Tue, Wed, Fri, Sat
Cheapest price
$90

Live departures

Orlando, FL to Charleston, SC bus times

The table below shows live departures for Orlando, FL to Charleston, SC buses for today, Friday, November 21. You can also manually refresh the results below to see updated bus journeys.

Last updated at 4:01 AM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbusFlixBus · FlixBus+greyhound9:45 AM Orlando, N John Young Pkwy (Greyhound Bus Station)
13h45
11:30 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Orlando, FL to Charleston, SC by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Nov 22
Sun
Nov 23
Mon
Nov 24
Tue
Nov 25
Wed
Nov 26
Thu
Nov 27
Fri
Nov 28
Sat
Nov 29
Sun
Nov 30
Mon
Dec 01
Tue
Dec 02
Wed
Dec 03
Thu
Dec 04
Fri
Dec 05

Journey information

Overview: Bus from Orlando, FL to Charleston, SC

USAUSA
USAUSA
Icon of bus

Buses from Orlando, FL to Charleston, SC run on average 2 times per day, taking around 8h 5m. Cheap bus tickets for this journey start at $44 (€36) if you book in advance.

There are 1 buses per day. The earliest bus runs at 04:00, the last at 23:40. The fastest bus covers the 305 miles (491 km) distance in 7h 50m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
305 miles (491 km)
Average bus duration
8h 5m
Cheapest ticket price
$44 (€36)
Buses per day
2
Direct buses
1
Fastest bus
7h 50m
First bus
04:00
Last bus
23:40
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound, FlixBus from Orlando, FL to Charleston, SCYou can travel by bus between Orlando, FL to Charleston, SC with Greyhound, FlixBus for as low as $44 (€36). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
7h 50m
Cheapest Price
$48 (€39)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
9h 5m
Cheapest Price
$62 (€50)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from Orlando, FL to Charleston, SC

Find answers to the most common questions about traveling from Orlando, FL to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Orlando, FL to Charleston, SC can start from as little as $62 (€50) when you book in advance. The average bus ticket price for Orlando, FL to Charleston, SC is $135 (€110); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Orlando, FL to Charleston, SC bus travel time is 9 h 5 min   for the 304 mile (491 km) long route, but the duration can vary if you travel on weekends and holidays.
The first bus from Orlando, FL to Charleston, SC leaves at 1: 35AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Orlando, FL to Charleston, SC leaves at 9: 00PM.
There is 1 bus a day from Orlando, FL to Charleston, SC which require at least one change with Greyhound or FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Orlando, FL to Charleston, SC, you can count on Greyhound or FlixBus for the best way to get you to Charleston, SC. You can also check all possible bus providers who offer a service from Orlando, FL to Charleston, SC and compare the amenities they offer before buying a bus ticket.
The cheapest month to travel from Orlando, FL to Charleston, SC by bus is September.
It's helpful to compare your options as there are 3 ways to travel from Orlando, FL to Charleston, SC including taking a bus, train or flight.
Yes, the following accessibility options are available when taking the bus from Orlando, FL to Charleston, SC:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Orlando, FL to Charleston, SC for bus providers Greyhound and FlixBus.
Yes, bikes are allowed on board the bus with bus providers Greyhound and FlixBus.
Whether you can cancel your bus ticket from Orlando, FL to Charleston, SC depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.

To find the cheapest bus tickets for your trip from Orlando, FL to Charleston, SC, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Orlando, FL to Charleston, SC.
    Yes, the following luggage options are included when booking a bus ticket from Orlando, FL to Charleston, SC:
    • Greyhound
      • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    • FlixBus
      • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
    Yes, the following additional luggage options are available when booking a bus ticket from Orlando, FL to Charleston, SC:
    • Greyhound
      • $15 per additional bag.
    • FlixBus
      • Additional luggage can be purchased for a fee.
    Yes, you can bring your pet on the bus from Orlando, FL to Charleston, SC. The following conditions apply:
    • FlixBus
      • Small pets in carriers allowed
      • Guide dogs travel for free.
    You can reserve your seat on the bus from Orlando, FL to Charleston, SC with the following bus providers: Greyhound and FlixBus
    Yes, there are USB plugs on board the bus from Orlando, FL to Charleston, SC with the following bus companies: Greyhound and FlixBus.
    Yes, there is Wifi on board the bus from Orlando, FL to Charleston, SC with the following bus providers: Greyhound and FlixBus.

    popular bus stations

    Popular bus stations from Orlando, FL to Charleston, SC

    Orlando
    Charleston
    The major bus station for departures in Orlando is Orlando, N John Young Pkwy (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Orlando, N John Young Pkwy (Greyhound Bus Station) for your trip from Orlando to Charleston.
    Orlando, N John Young Pkwy (Greyhound Bus Station)
    information

    More options for your journey from Orlando, FL to Charleston, SC

    Here are some other resources that might have the information you need

    HomeBusesBuses in USAOrlando, FL to Charleston, SC bus

    The Omio App Makes Travel Planning Easy

    We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

    ios-badge
    android-badge
    Hand With Phone