1,000+ travel companies
1,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from Orlando, FL to Charleston, SC
Showing times and prices for Feb 25
Cheapest price
$213
Average price
$213
Fastest journey
14 h 30 m
Average duration
14 h 30 m
Buses per day
1
Distance
491 km
Cheap tickets
The best way to find a cheap bus ticket from Orlando, FL to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Orlando, FL to Charleston, SC will cost around $213 if you buy it on the day, but the cheapest tickets can be found for only $213.
Fast buses
It's difficult to get from Orlando, FL to Charleston, SC without transferring at least once.
FlixBus+
04:00AM14h30
Orlando, N John Young Pkwy (Greyhound Bus Station)06:30PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC
$2131One-way
1 transfer
FlixBus+04:00AM14h30
Orlando, N John Young Pkwy (Greyhound Bus Station)06:30PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC
$2131One-way
1 transfer
Travel Information
Compare bus, train, and flight for Orlando, FL to Charleston, SC
Omio recommends booking the train as it is the most popular option from Orlando, FL to Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from $49. For those with little time consider booking a flight which can get you there in 2h 17m. The ticket price range depends on the travel mode: a bus costs an average of $49, and a flight costs an average of $42.
Distance: 305 miles (491 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$107 Average price Cheapest | $118 Average price | $207 Average price |
8h 35m Average total duration 8h 5m Onboard + 30m Additional time* | 8h 16m Average total duration 7h 46m Onboard + 30m Additional time* | 5h 17m Average total duration Fastest 2h 17m Onboard + 3h 0m Additional time* |
Most popular bus company |  Most popular train company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
Orlando, FL to Charleston, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:00AM | Arrival Time 06:30PM | Duration 14h30 | Departure days Tue, Wed | Cheapest price $213 |
Operator FlixBus | Departure Time 04:45AM | Arrival Time 06:30PM | Duration 13h45 | Departure days Thu, Fri, Sun | Cheapest price $74 |
Live departures
Orlando, FL to Charleston, SC bus times
The table below shows live departures for Orlando, FL to Charleston, SC buses for tomorrow, Wednesday, February 25. You can also manually refresh the results below to see updated bus journeys.
Last updated at 2:13 PM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus+ | 9:00 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 14h30 | 11:30 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Orlando, FL to Charleston, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Wed
Feb 25
Feb 25
Thu
Feb 26
Feb 26
Fri
Feb 27
Feb 27
Sat
Feb 28
Feb 28
Sun
Mar 01
Mar 01
Mon
Mar 02
Mar 02
Tue
Mar 03
Mar 03
Wed
Mar 04
Mar 04
Thu
Mar 05
Mar 05
Fri
Mar 06
Mar 06
Sat
Mar 07
Mar 07
Sun
Mar 08
Mar 08
Mon
Mar 09
Mar 09
Tue
Mar 10
Mar 10
Why should you book Orlando, FL to Charleston, SC buses with Omio?
Greyhound as well as FlixBus offer buses services from Orlando, FL to Charleston, SC.
Omio is an official ticket reseller for all your travel options from Orlando, FL to Charleston, SC.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Orlando, FL to Charleston, SC.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Orlando, FL to Charleston, SC.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Orlando, FL to Charleston, SC.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Orlando, FL to Charleston, SC.
Journey information
Overview: Bus from Orlando, FL to Charleston, SC
USAUSA
Buses from Orlando, FL to Charleston, SC run on average 2 times per day, taking around 8h 5m. Cheap bus tickets for this journey start at $49 (€39) but you can travel from only $42 (€34) by flight.
There are 1 buses per day. The earliest bus runs at 04:00, the last at 23:40. The fastest bus covers the 305 miles (491 km) distance in 9h 50m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $42 (€34)
Distance 305 miles (491 km) |
Average bus duration 8h 5m |
Cheapest ticket price $49 (€39) |
Buses per day 2 |
Direct buses 1 |
Fastest bus 9h 50m |
First bus 04:00 |
Last bus 23:40 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $42 (€34)
Bus providers: Greyhound, FlixBus from Orlando, FL to Charleston, SCYou can travel by bus between Orlando, FL to Charleston, SC with Greyhound, FlixBus for as low as $42 (€34). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
9h 50m
Cheapest Price
$49 (€39)
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
9h 5m
Cheapest Price
$63 (€50)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
FAQs: Bus from Orlando, FL to Charleston, SC
Find answers to the most common questions about traveling from Orlando, FL to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Orlando, FL to Charleston, SC can start from as little as $49 (€39) when you book in advance. The average bus ticket price for Orlando, FL to Charleston, SC is $107 (€85) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Orlando, FL to Charleston, SC is 9h 50m to travel the 305 miles (491 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Orlando, FL to Charleston, SC leaves at 4:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Orlando, FL to Charleston, SC leaves at 11:40 PM.
Yes, there are 1 direct buses a day from Orlando, FL to Charleston, SC with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Orlando, FL to Charleston, SC, you can count on Greyhound, FlixBus for the best way to get you to Charleston, SC. You can also check all possible bus companies who offer a service between Orlando, FL and Charleston, SC and compare the amenities they offer before buying a bus ticket.
A trip to Charleston, SC from Orlando, FL is worth doing but not as a day trip with a journey time of 9h 50m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Orlando, FL to Charleston, SC is February.
It's helpful to compare your options as there are 3 ways to travel between Orlando, FL and Charleston, SC including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Orlando, FL to Charleston, SC:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Orlando, FL to Charleston, SC for bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from Orlando, FL to Charleston, SC depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Orlando, FL to Charleston, SC.
Yes, the following luggage options are included when booking a bus ticket from Orlando, FL to Charleston, SC:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Orlando, FL to Charleston, SC:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Orlando, FL to Charleston, SC. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Orlando, FL to Charleston, SC with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Orlando, FL to Charleston, SC with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Orlando, FL to Charleston, SC with the following bus company: Greyhound, FlixBus.
popular bus stations
Popular bus stations from Orlando, FL to Charleston, SC
Orlando
Charleston
The major bus station for departures in Orlando is Orlando, N John Young Pkwy (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Orlando, N John Young Pkwy (Greyhound Bus Station) for your trip from Orlando to Charleston.
Orlando, N John Young Pkwy (Greyhound Bus Station)
information
The major bus station for arrivals in Charleston is Charleston, Gaynor Avenue (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Charleston, Gaynor Avenue (Greyhound Bus Station) for your trip to Charleston from Orlando.
Charleston, Gaynor Avenue (Greyhound Bus Station)
information
Most popular bus connections from Orlando, FL
More options for your journey from Orlando, FL to Charleston, SC
Here are some other resources that might have the information you need
Most popular buses to and from Charleston, SC and Orlando, FL
Most popular bus connections to Charleston, SC
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
