- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Buses from Los Angeles, CA to Charleston, SC run on average 2 times per day, taking around 56h 43m. Cheap bus tickets for this journey start at $196 but you can travel from only $134 by flight.
The earliest bus runs at 09:35, the last at 23:30. The fastest bus covers the 2198 miles (3538 km) distance in 52h 0m.
Distance 2198 miles (3538 km) |
Average bus duration 56h 43m |
Cheapest ticket price $196 |
Buses per day 2 |
Fastest bus 52h 0m |
First bus 9:35 AM |
Last bus 11:30 PM |
Cheapest Month Feb |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jul - Sep |
Best time to book 1 day |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Los Angeles, CA to Charleston, SC.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:30AM | Arrival Time 10:30PM | Duration 66h00 | Departure days Sat | Cheapest price $290 |
Operator Greyhound | Departure Time 06:30AM | Arrival Time 10:30PM | Duration 64h00 | Departure days Fri | Cheapest price $338 |
Operator Greyhound | Departure Time 04:35PM | Arrival Time 10:30PM | Duration 77h55 | Departure days Fri | Cheapest price $519 |
Operator Greyhound | Departure Time 08:20PM | Arrival Time 10:30PM | Duration 74h10 | Departure days Thu, Sat | Cheapest price $417 |
Operator Greyhound | Departure Time 09:20PM | Arrival Time 11:30PM | Duration 74h10 | Departure days Mon, Sat | Cheapest price $152 |
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Charleston, SC.
Find answers to the most common questions about traveling from Los Angeles, CA to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

Most Los Angeles, CA to Charleston, SC buses use the Los Angeles, Patsaouras Transit Plaza (Union Station) to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Los Angeles, CA and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Los Angeles, Patsaouras Transit Plaza (Union Station) is 1 km from Los Angeles city centre. Public transport options include:
Los Angeles, Patsaouras Transit Plaza (Union Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Food court and various dining options available.
Wi-Fi available in main waiting areas. ATMs are aTMs available near main concourse.
Ticket office support is available at Los Angeles, Patsaouras Transit Plaza (Union Station).
Available at Los Angeles, Patsaouras Transit Plaza (Union Station): Parking, Taxis, WC.
Accessibility facilities are available at Los Angeles, Patsaouras Transit Plaza (Union Station): Station fully accessible with elevators and ramps.
Los Angeles, Cesar E Chavez / Vignes is 1 km from Los Angeles city centre. Public transport options include:
Los Angeles, Cesar E Chavez / Vignes has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Los Angeles, Cesar E Chavez / Vignes. ATMs are available at Los Angeles, Cesar E Chavez / Vignes.
Ticket office support is available at Los Angeles, Cesar E Chavez / Vignes.
Available at Los Angeles, Cesar E Chavez / Vignes: Parking, Taxis, WC.
Accessibility facilities are available at Los Angeles, Cesar E Chavez / Vignes: The station is accessible to people with disabilities.
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
Check bus stations information for Los Angeles, CA and Charleston, SC, including where buses depart and arrive on this route.
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