- Must visit
Uffizi Gallery
Celebrated art museum with Botticelli, Leonardo, and Michelangelo. A cornerstone visit for Renaissance painting and one of Florence’s defining experiences.
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Journey information
Overview: Bus from Charleston, SC to Florence, SC
USAUSA
Buses from Charleston, SC to Florence, SC run on average 1 times per day, taking around 4h 1m. Cheap bus tickets for this journey start at €21 but you can travel from only €20 by train.
There are 1 buses per day. The earliest bus runs at 11:15, the last at 14:10. The fastest bus covers the 98 miles (159 km) distance in 3h 30m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from €20
Plan this route
Journey facts
- Distance98 miles (159 km)
- Average bus duration4h 1m
- Cheapest ticket price€21
- Buses per day1
- Direct buses1
- Fastest bus3h 30m
- First bus11:15 AM
- Last bus2:10 PM
- Cheapest MonthJun
- Cheapest DaySun
- High SeasonJul - Sep
- Low SeasonApr - Jun
- Busiest DayFri
- Least Busy DayTue
- Best time to book4 days
Understand & plan this route
Explore this journey
Book with confidence
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from €20
Frequently asked questions about your Charleston, SC to Florence, SC trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Charleston, SC to Florence, SC.
Cheap bus tickets from Charleston, SC to Florence, SC can start from as little as €21 when you book in advance. The average bus ticket price for Charleston, SC to Florence, SC is €28 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from Charleston, SC to Florence, SC leaves at 11:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Charleston, SC to Florence, SC leaves at 2:10 PM.
Yes, there are 1 direct buses a day from Charleston, SC to Florence, SC with Greyhound. Schedules can vary on holidays or weekends with fewer direct buses.
Charleston, SC to Florence, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 10:00AM | Arrival Time 02:20PM | Duration 4h20 | Departure days Mon | Cheapest price €30 |
Operator Greyhound | Departure Time 10:40AM | Arrival Time 02:55PM | Duration 4h15 | Departure days Mon | Cheapest price €26 |
Operator Greyhound | Departure Time 03:15PM | Arrival Time 07:35PM | Duration 4h20 | Departure days Thu, Fri, Sat | Cheapest price €22 |
Operator Greyhound | Departure Time 04:15PM | Arrival Time 08:35PM | Duration 4h20 | Departure days Thu, Fri, Sat | Cheapest price €28 |
Live departures
Charleston, SC to Florence, SC bus times
The table below shows live departures for Charleston, SC to Florence, SC buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 10:40 AM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 4h15 | 2:55 PM Florence, S Irby St (Greyhound Bus Stop), SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Charleston, SC to Florence, SC buses with Omio?
Greyhound operates all buses services from Charleston, SC to Florence, SC.
Omio is an official ticket reseller for all your travel options from Charleston, SC to Florence, SC.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and train to ensure you get the best deal for traveling from Charleston, SC to Florence, SC.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Charleston, SC to Florence, SC.
Bus companies
Bus companies from Charleston, SC to Florence, SC
Buses from Charleston, SC to Florence, SC with Greyhound. Overnight buses available on this route with Greyhound. Use the details below to compare onboard facilities.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
3h 30m
Cheapest Greyhound Price
€21
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Companies, tickets, and onboard amenities between Charleston, SC and Florence, SC
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from Charleston, SC to Florence, SC, you can count on Greyhound for the best way to get you to Florence, SC. You can also check all possible bus companies who offer a service between Charleston, SC and Florence, SC and compare the amenities they offer before buying a bus ticket.
Yes, there are bathrooms on board the bus from Charleston, SC to Florence, SC for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from Charleston, SC to Florence, SC:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from Charleston, SC to Florence, SC depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Yes, there is food available to purchase on board the bus from Charleston, SC to Florence, SC.
Yes, the following luggage options are included when booking a bus ticket from Charleston, SC to Florence, SC:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Charleston, SC to Florence, SC:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Charleston, SC to Florence, SC.
You can reserve your seat on the bus from Charleston, SC to Florence, SC with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Charleston, SC to Florence, SC with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Charleston, SC to Florence, SC with the following bus company: Greyhound.
Complete guide to Florence, SC
Things to do in Florence, SC
Discover the best of Florence, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence, SC trip today.
- Must visit
Galleria dell'Accademia
Museum centered on Michelangelo’s David, plus sculptures and paintings. Essential for seeing one of Florence’s most famous masterpieces up close.
- Recommended
Museo dell'Opera del Duomo
Interactive museum inside the cathedral complex exploring Brunelleschi’s dome, tools, and original artworks. Ideal for understanding Florence’s cathedral story.
- Must visit
Piazza della Signoria
Grand civic square framed by Palazzo Vecchio and open-air sculptures. It is one of Florence’s key meeting points and a natural starting place for exploration.
- Must visit
Piazzale Michelangelo
Hilltop terrace with sweeping city views, especially at sunset. A classic Florence panorama and a rewarding walk or short bus ride from the center.
- Recommended
Boboli Gardens
Large formal garden behind Pitti Palace with paths, fountains, and viewpoints. Excellent for a slower visit combining greenery, sculpture, and city vistas.
- Gluten-free
Pee Dee Pulled Pork BBQ
Pulled pork barbecue is a Pee Dee staple, slow-smoked until tender and served with the region's tangy vinegar-pepper sauce.
- Gluten-free
Smoked Pork Ribs
Smoked pork ribs are common at local barbecue joints, seasoned simply and cooked low and slow for deep smoke flavor.
- Gluten-free
Shrimp and Grits
Shrimp and grits is a South Carolina classic: local shrimp over creamy grits, often enriched with bacon, gravy, or butter.
Victors
Upscale downtown restaurant serving refined Southern dishes, steaks, seafood, and cocktails in a polished space.
Wholly Smokin' Downtown
Casual local favorite for Carolina barbecue, ribs, and classic Southern sides in a relaxed family setting.
Holt Bros BBQ
Popular casual spot known for barbecue plates, pulled pork, and generous Southern comfort food portions.
$ US Dollar
Moderate by U.S. small-city standards. Hotels are usually cheaper than major tourist cities, while dining and car-based transport remain fairly typical for the region.
Average meal costs
- Budget
- $8-12 for fast food or casual takeout.
- Mid-range
- $15-25 per person for a casual sit-down meal.
- Fine dining
- $35+ per person for upscale restaurants.
- Coffee
- $3-5 for regular coffee or latte.
Tipping culture
Tip 15-20% at restaurants. Round up or add 10-15% for taxis if service is good. Small change is fine at cafes.
Plan your visit to Florence, SC
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Florence, SC.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Florence, SC, travelers should be cautious of petty crimes like pickpocketing and vehicle break-ins, especially in less crowded areas. It's advisable to stay in well-lit, populated places and avoid displaying valuables openly. Common scams include overcharging by taxi drivers and unofficial ticket sellers; always use licensed transportation and purchase tickets from authorized vendors. Staying aware of surroundings and securing personal belongings helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from Charleston, SC to Florence, SC
Find answers to the most common questions about traveling from Charleston, SC to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.
It's helpful to compare your options as there are 2 ways to travel between Charleston, SC and Florence, SC including taking a bus and train.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Popular bus stations from Charleston, SC to Florence, SC
Most Charleston, SC to Florence, SC buses use the Charleston, Gaynor Avenue (Greyhound Bus Station) to Florence, S Irby St (Greyhound Bus Stop) station pair. Use this guide to compare Charleston, SC and Florence, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Charleston
Arrival bus stations in Florence
Which Charleston, SC station do buses to Florence, SC leave from?
Buses from Charleston, SC to Florence, SC leave from Charleston, Gaynor Avenue (Greyhound Bus Station). The station is 8 miles (13 km) from Charleston, SC city centre at 4565 Gaynor Ave, Charleston, SC 29405, USA.
Charleston, Gaynor Avenue (Greyhound Bus Station)4565 Gaynor Ave, Charleston, SC 29405, USA
City-centre transport
Getting to Charleston, Gaynor Avenue (Greyhound Bus Station) from Charleston city centre
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Bus10 · 32m · every ~4 min
10 · 41m · every ~4 min
Charleston, Gaynor Avenue (Greyhound Bus Station) bus station facilities and services
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Parking, taxis and toilets
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
Which Florence, SC station do buses from Charleston, SC arrive at?
Buses from Charleston, SC to Florence, SC arrive at Florence, S Irby St (Greyhound Bus Stop). Florence, S Irby St (Greyhound Bus Stop) is 0 miles (1 km) from Florence, SC city centre.
Florence, S Irby St (Greyhound Bus Stop)S Irby St, Florence, SC, USA
City-centre transport
Getting to Florence, S Irby St (Greyhound Bus Stop) from Florence city centre
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Florence, S Irby St (Greyhound Bus Stop) bus station facilities and services
Florence, S Irby St (Greyhound Bus Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Florence, S Irby St (Greyhound Bus Stop). ATMs are available at Florence, S Irby St (Greyhound Bus Stop).
Tickets and information
Ticket office support is available at Florence, S Irby St (Greyhound Bus Stop).
Parking, taxis and toilets
Available at Florence, S Irby St (Greyhound Bus Stop): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence, S Irby St (Greyhound Bus Stop): Bus stop accessible for disabled persons.
Bus stations for Charleston, SC to Florence, SC
Check bus stations information for Charleston, SC and Florence, SC, including where buses depart and arrive on this route.
Passengers board the bus most frequently from Charleston, Gaynor Avenue (Greyhound Bus Station), which is located around 8 miles (13 km) away from the city centre, and they get off the bus at Florence, S Irby St (Greyhound Bus Stop), located 1 away from the city centre.
Most popular buses to and from Florence, SC and Charleston, SC
Most popular bus connections to Florence, SC
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