- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
The best way to find a cheap bus ticket from Boston, MA to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Boston, MA to Charleston, SC will cost around CHF 134 if you buy it on the day, but the cheapest tickets can be found for only CHF 131.
It's difficult to get from Boston, MA to Charleston, SC without transferring at least 2 times.
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Buses from Boston, MA to Charleston, SC run on average 3 times per day, taking around 23h 25m. Cheap bus tickets for this journey start at CHF 64 but you can travel from only CHF 59 by flight.
The earliest bus runs at 08:00, the last at 21:50. The fastest bus covers the 820 miles (1320 km) distance in 20h 30m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Boston, MA to Charleston, SC.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:00AM | Arrival Time 12:15PM | Duration 35h15 | Departure days Thu | Cheapest price CHF 79 |
Operator Greyhound | Departure Time 02:30AM | Arrival Time 12:15PM | Duration 33h45 | Departure days Wed | Cheapest price CHF 82 |
Operator FlixBus | Departure Time 08:00AM | Arrival Time 12:15PM | Duration 28h15 | Departure days Mon, Fri, Sat, Sun | Cheapest price CHF 75 |
Operator Greyhound | Departure Time 01:05PM | Arrival Time 02:05PM | Duration 25h00 | Departure days Tue | Cheapest price CHF 137 |
Operator Greyhound | Departure Time 01:15PM | Arrival Time 01:40PM | Duration 24h25 | Departure days Thu | Cheapest price CHF 97 |
Operator Greyhound | Departure Time 04:45PM | Arrival Time 06:30PM | Duration 25h45 | Departure days Everyday | Cheapest price CHF 73 |
Operator FlixBus | Departure Time 08:15PM | Arrival Time 09:50PM | Duration 25h35 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price CHF 90 |
Operator Greyhound | Departure Time 09:50PM | Arrival Time 06:30PM | Duration 44h40 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price CHF 77 |
Operator FlixBus | Departure Time 09:50PM | Arrival Time 12:15PM | Duration 38h25 | Departure days Sun | Cheapest price CHF 103 |
The table below shows live departures for Boston, MA to Charleston, SC buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus+![]() | 8:00 AM Boston, Bus Terminal South Station | 28h15 | 12:15 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
· · · | 4:45 PM Boston, Bus Terminal South Station | 25h45 | 6:30 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
FlixBus+ · | 8:15 PM Boston, Bus Terminal South Station | 25h35 | 9:50 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 2 transfers | |
FlixBus · FlixBus+ · | 9:50 PM Boston, Bus Terminal South Station | 38h25 | 12:15 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Boston, MA to Charleston, SC with Greyhound and FlixBus. Overnight buses available on this route with Greyhound and FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Charleston, SC.
Find answers to the most common questions about traveling from Boston, MA to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

Most Boston, MA to Charleston, SC buses use the Boston, Bus Terminal South Station to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Boston, MA and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Boston, Bus Terminal South Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several fast food and cafe options available.
Free Wi-Fi available throughout the terminal. ATMs are aTMs located inside the terminal.
Ticket office support is available at Boston, Bus Terminal South Station.
Available at Boston, Bus Terminal South Station: Parking, Taxis, WC.
Accessibility facilities are available at Boston, Bus Terminal South Station: Fully accessible with ramps and elevators.
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
Check bus stations information for Boston, MA and Charleston, SC, including where buses depart and arrive on this route.