- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Cheapest price
$110
Average price
$111
Fastest journey
20 h 50 m
Average duration
1 d 1 h 5 m
Buses per day
6
Distance
845 km
The best way to find a cheap bus ticket from Columbus, OH to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Columbus, OH to Charleston, SC will cost around $111 if you buy it on the day, but the cheapest tickets can be found for only $110.
It's difficult to get from Columbus, OH to Charleston, SC without transferring at least 2 times.
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· · Omio recommends booking the flight as it is the most popular option from Columbus, OH to Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from $98. For those with little time consider booking a flight which can get you there in 4h 15m. The ticket price range depends on the travel mode: a bus costs an average of $98, and a flight costs an average of $68.
Distance: 525 miles (845 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
$153 Average price Cheapest | $553 Average price | $144 Average price (fuel + tolls) |
23h 27m Average total duration 22h 57m Onboard + 30m Additional time* | 7h 15m Average total duration Fastest 4h 15m Onboard + 3h 0m Additional time* | 9h 47m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Columbus, OH to Charleston, SC:
A bus is $415 less than a flight for this route with tickets for a flight from Columbus, OH to Charleston, SC costing on average $567.
Other travel options to Charleston, SC take longer:
Bus takes on average 22h 52m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:50AM | Arrival Time 09:40PM | Duration 20h50 | Departure days Wed | Cheapest price $111 |
Operator Greyhound | Departure Time 05:20AM | Arrival Time 09:10AM | Duration 27h50 | Departure days Wed, Thu, Fri, Sat | Cheapest price $105 |
Operator FlixBus | Departure Time 07:45AM | Arrival Time 10:30PM | Duration 38h45 | Departure days Sun | Cheapest price $182 |
Operator Greyhound | Departure Time 09:45AM | Arrival Time 12:15PM | Duration 26h30 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $105 |
Operator Greyhound | Departure Time 11:00AM | Arrival Time 06:30PM | Duration 31h30 | Departure days Mon, Tue, Thu, Fri, Sat | Cheapest price $106 |
Operator Greyhound | Departure Time 01:55PM | Arrival Time 06:30PM | Duration 28h35 | Departure days Mon, Tue, Thu, Fri, Sat | Cheapest price $108 |
Operator Greyhound | Departure Time 02:00PM | Arrival Time 06:30PM | Duration 28h30 | Departure days Wed | Cheapest price $110 |
Operator Greyhound | Departure Time 02:45PM | Arrival Time 11:30PM | Duration 32h45 | Departure days Sun | Cheapest price $131 |
Operator FlixBus | Departure Time 05:20PM | Arrival Time 09:10AM | Duration 39h50 | Departure days Thu, Fri | Cheapest price $126 |
Operator Greyhound | Departure Time 05:20PM | Arrival Time 09:40PM | Duration 28h20 | Departure days Wed | Cheapest price $112 |
Operator Greyhound | Departure Time 06:00PM | Arrival Time 10:30PM | Duration 28h30 | Departure days Sun | Cheapest price $182 |
Operator Greyhound | Departure Time 07:00PM | Arrival Time 11:30PM | Duration 28h30 | Departure days Sun | Cheapest price $241 |
Operator Greyhound | Departure Time 09:10PM | Arrival Time 09:40PM | Duration 24h30 | Departure days Wed | Cheapest price $112 |
The table below shows live departures for Columbus, OH to Charleston, SC buses for today, Tuesday, August 25. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ · · | 9:45 AM Columbus, E Town St (Bus Station), OH | 26h30 | 12:15 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
FlixBus · FlixBus+![]() | 11:00 AM Columbus, E Town St (Bus Station), OH | 31h30 | 6:30 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 2 transfers | |
· · · | 1:55 PM Columbus, E Mound St (Akili Christian High School), OH | 28h35 | 6:30 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 4 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Columbus, OH to Charleston, SC run on average 4 times per day, taking around 22h 52m. Cheap bus tickets for this journey start at $98 but you can travel from only $68 by flight.
The earliest bus runs at 04:00, the last at 23:30. The fastest bus covers the 525 miles (845 km) distance in 18h 0m.
Distance 525 miles (845 km) |
Average bus duration 22h 52m |
Cheapest ticket price $98 |
Buses per day 4 |
Fastest bus 18h 0m |
First bus 4:00 AM |
Last bus 11:30 PM |
Cheapest Month Sep |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Jan - Mar |
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
Find answers to the most common questions about traveling from Columbus, OH to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

Most Columbus, OH to Charleston, SC buses use the Columbus, E Town St (Bus Station) to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Columbus, OH and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Columbus, E Town St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Columbus, E Town St (Bus Station). ATMs are available at Columbus, E Town St (Bus Station).
Ticket office support is available at Columbus, E Town St (Bus Station).
Available at Columbus, E Town St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Columbus, E Town St (Bus Station): Wheelchair accessible bus platforms.
Columbus, E Mound St (Akili Christian High School) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Columbus, E Mound St (Akili Christian High School). ATMs are available at Columbus, E Mound St (Akili Christian High School).
Ticket office support is available at Columbus, E Mound St (Akili Christian High School).
Available at Columbus, E Mound St (Akili Christian High School): Parking, Taxis, WC.
Accessibility facilities are available at Columbus, E Mound St (Akili Christian High School): Wheelchair accessible buses available.
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
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