- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Cheapest price
€57
Average price
€57
Fastest journey
22 h 15 m
Average duration
22 h 15 m
Buses per day
1
Distance
589 km
The best way to find a cheap bus ticket from Tampa, FL to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Tampa, FL to Charleston, SC will cost around €57 if you buy it on the day, but the cheapest tickets can be found for only €57.
It's difficult to get from Tampa, FL to Charleston, SC without transferring at least 3 times.
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FlixBus · FlixBus+
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FlixBus · FlixBus+
Buses from Tampa, FL to Charleston, SC run on average 3 times per day, taking around 19h 51m. Cheap bus tickets for this journey start at €59 but you can travel from only €46 by flight.
The earliest bus runs at 04:56, the last at 22:35. The fastest bus covers the 365 miles (589 km) distance in 18h 50m.
Distance 365 miles (589 km) |
Average bus duration 19h 51m |
Cheapest ticket price €59 |
Buses per day 3 |
Fastest bus 18h 50m |
First bus 4:56 AM |
Last bus 10:35 PM |
Cheapest Month Sep |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 6 days |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 11:10AM | Arrival Time 09:25AM | Duration 22h15 | Departure days Everyday | Cheapest price €55 |
The table below shows live departures for Tampa, FL to Charleston, SC buses for tomorrow, Wednesday, August 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
+ FlixBus · FlixBus+![]() | 11:10 AM Tampa, Marion Transit Center | 22h15 | 9:25 AM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
Find answers to the most common questions about traveling from Tampa, FL to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

Most Tampa, FL to Charleston, SC buses use the Tampa, Marion Transit Center to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Tampa, FL and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Tampa, Marion Transit Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Tampa, Marion Transit Center. ATMs are available at Tampa, Marion Transit Center.
Ticket office support is available at Tampa, Marion Transit Center.
Available at Tampa, Marion Transit Center: Parking, Taxis, WC.
Accessibility facilities are available at Tampa, Marion Transit Center: Wheelchair accessible with ramps.
Tampa, USF Holly Drive (Central Plant) is 13 km from Tampa city centre. Public transport options include:
Tampa, USF Holly Drive (Central Plant) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Tampa, USF Holly Drive (Central Plant). ATMs are available at Tampa, USF Holly Drive (Central Plant).
Ticket office support is available at Tampa, USF Holly Drive (Central Plant).
Available at Tampa, USF Holly Drive (Central Plant): Parking, Taxis, WC.
Accessibility facilities are available at Tampa, USF Holly Drive (Central Plant): Wheelchair accessible facilities.
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
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