- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
The best way to find a cheap bus ticket from Cleveland, OH to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Cleveland, OH to Charleston, SC will cost around €87 if you buy it on the day, but the cheapest tickets can be found for only €87.
It's difficult to get from Cleveland, OH to Charleston, SC without transferring at least 3 times.
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Buses from Cleveland, OH to Charleston, SC run on average 3 times per day, taking around 27h 18m. Cheap bus tickets for this journey start at €67 if you book in advance.
The earliest bus runs at 02:35, the last at 16:40. The fastest bus covers the 610 miles (982 km) distance in 21h 10m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Cleveland, OH to Charleston, SC.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:20AM | Arrival Time 10:30PM | Duration 46h10 | Departure days Sat | Cheapest price €220 |
Operator Greyhound | Departure Time 04:25AM | Arrival Time 09:10AM | Duration 28h45 | Departure days Wed, Thu | Cheapest price €90 |
Operator Greyhound | Departure Time 10:15AM | Arrival Time 10:30PM | Duration 36h15 | Departure days Sat, Sun | Cheapest price €102 |
Operator Greyhound | Departure Time 11:35AM | Arrival Time 06:30PM | Duration 30h55 | Departure days Wed | Cheapest price €107 |
Operator Greyhound | Departure Time 03:50PM | Arrival Time 09:50PM | Duration 30h00 | Departure days Wed, Thu | Cheapest price €91 |
Operator FlixBus | Departure Time 08:20PM | Arrival Time 12:15PM | Duration 39h55 | Departure days Tue, Thu | Cheapest price €87 |
Operator Greyhound | Departure Time 08:30PM | Arrival Time 10:30PM | Duration 26h00 | Departure days Mon, Sat | Cheapest price €228 |
Operator Greyhound | Departure Time 08:50PM | Arrival Time 10:30PM | Duration 25h40 | Departure days Sun | Cheapest price €82 |
Operator Greyhound | Departure Time 09:30PM | Arrival Time 11:30PM | Duration 26h00 | Departure days Fri, Sat | Cheapest price €193 |
The table below shows live departures for Cleveland, OH to Charleston, SC buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:30 PM Cleveland, OH | 26h00 | 10:30 PM Charleston, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Cleveland, OH to Charleston, SC with Greyhound and FlixBus. Overnight buses available on this route with Greyhound and FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Charleston, SC.
Find answers to the most common questions about traveling from Cleveland, OH to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

Most Cleveland, OH to Charleston, SC buses use the Cleveland, Chester Ave At the Greyhound Station (South Side) to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Cleveland, OH and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Cleveland, Chester Ave At the Greyhound Station (South Side) is 1 km from Cleveland city centre. Public transport options include:
Cleveland, Chester Ave At the Greyhound Station (South Side) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack bar available onsite.
Free WiFi available for passengers. ATMs are available at Cleveland, Chester Ave At the Greyhound Station (South Side).
Ticket office support is available at Cleveland, Chester Ave At the Greyhound Station (South Side).
Available at Cleveland, Chester Ave At the Greyhound Station (South Side): Parking, Taxis, WC.
Accessibility facilities are available at Cleveland, Chester Ave At the Greyhound Station (South Side): Station is wheelchair accessible.
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
Check bus stations information for Cleveland, OH and Charleston, SC, including where buses depart and arrive on this route.