- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Cheapest price
$128
Average price
$137
Fastest journey
18 h 25 m
Average duration
21 h 24 m
Buses per day
5
Distance
905 km
The best way to find a cheap bus ticket from Philadelphia, PA to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Philadelphia, PA to Charleston, SC will cost around $137 if you buy it on the day, but the cheapest tickets can be found for only $128.
It's difficult to get from Philadelphia, PA to Charleston, SC without transferring at least 2 times.
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· Omio recommends booking the train as it is the most popular option from Philadelphia, PA to Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from $68. For those with little time consider booking a flight which can get you there in 2h 34m. The ticket price range depends on the travel mode: a bus costs an average of $68, and a flight costs an average of $90.
Distance: 562 miles (905 km)
| Bus | Most popular Train | Flight |
|---|---|---|
$144 Average price Cheapest | $156 Average price | $287 Average price |
22h 10m Average total duration 21h 40m Onboard + 30m Additional time* | 12h 58m Average total duration 12h 28m Onboard + 30m Additional time* | 5h 34m Average total duration Fastest 2h 34m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Philadelphia, PA to Charleston, SC:
A bus is $12 (€12) less than a train for this route with tickets for a train from Philadelphia, PA to Charleston, SC costing on average $156 (€156).
A bus is $143 (€143) less than a flight for this route with tickets for a flight from Philadelphia, PA to Charleston, SC costing on average $287 (€287).
Other travel options to Charleston, SC take longer:
Train takes on average 12h 28m.
Bus takes on average 21h 40m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:05AM | Arrival Time 06:30PM | Duration 18h25 | Departure days Everyday | Cheapest price $100 |
Operator Greyhound | Departure Time 12:50AM | Arrival Time 09:40PM | Duration 20h50 | Departure days Mon, Thu, Sat | Cheapest price $98 |
Operator Greyhound | Departure Time 03:05AM | Arrival Time 09:40PM | Duration 18h35 | Departure days Tue, Wed, Fri, Sun | Cheapest price $95 |
Operator Greyhound | Departure Time 02:30PM | Arrival Time 12:45PM | Duration 22h15 | Departure days Wed, Thu | Cheapest price $128 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 12:45PM | Duration 19h30 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $105 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 06:30PM | Duration 22h20 | Departure days Wed, Thu | Cheapest price $165 |
Operator Greyhound | Departure Time 10:00PM | Arrival Time 06:30PM | Duration 20h30 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $95 |
Operator Greyhound | Departure Time 10:30PM | Arrival Time 09:40PM | Duration 23h10 | Departure days Everyday | Cheapest price $103 |
The table below shows live departures for Philadelphia, PA to Charleston, SC buses for today, Wednesday, July 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ · | 2:30 PM Philadelphia Bus Station | 22h15 | 12:45 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 2 transfers | |
· · · | 8:10 PM Philadelphia Bus Station | 22h20 | 6:30 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
FlixBus+ · | 10:30 PM Philadelphia Bus Station | 23h20 | 9:50 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 2 transfers | |
| Thursday, July 23 | |||||
· · · | 12:05 AM Philadelphia Bus Station | 18h25 | 6:30 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
· · | 12:50 AM Philadelphia Bus Station | 20h50 | 9:40 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 2 transfers | |
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Philadelphia, PA to Charleston, SC run on average 5 times per day, taking around 21h 40m. Cheap bus tickets for this journey start at $68 (€68) if you book in advance.
The earliest bus runs at 07:10, the last at 23:55. The fastest bus covers the 562 miles (905 km) distance in 19h 30m.
Distance 562 miles (905 km) |
Average bus duration 21h 40m |
Cheapest ticket price $68 (€68) |
Buses per day 5 |
Fastest bus 19h 30m |
First bus 7:10 AM |
Last bus 11:55 PM |
Cheapest Month Sep |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Wed |
Least Busy Day Fri |
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
Find answers to the most common questions about traveling from Philadelphia, PA to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

Most Philadelphia, PA to Charleston, SC buses use the Philadelphia, Greyhound Bus Station to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Philadelphia, PA and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need