- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Cheapest price
$187
Average price
$187
Fastest journey
21 h 5 m
Average duration
21 h 5 m
Buses per day
1
Distance
869 km
The best way to find a cheap bus ticket from Wilmington, DE to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Wilmington, DE to Charleston, SC will cost around $187 if you buy it on the day, but the cheapest tickets can be found for only $187.
Of the 1 buses that leave Wilmington, DE for Charleston, SC on Fri, Aug 07, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Aug 07 the direct buses cover the 869 km distance in an average of 21 h 5 m but if you time it right, some buses will get you there in just 21 h 5 m .
On Fri, Aug 07 the slowest buses will take 21 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Buses from Wilmington, DE to Charleston, SC run on average 1 times per day, taking around 21h 5m. Cheap bus tickets for this journey start at $88 but you can travel from only $84 by flight.
The earliest bus runs at 11:15, the last at 21:25. The fastest bus covers the 539 miles (869 km) distance in 21h 5m.
Distance 539 miles (869 km) |
Average bus duration 21h 5m |
Cheapest ticket price $88 |
Buses per day 1 |
Fastest bus 21h 5m |
First bus 11:15 AM |
Last bus 9:25 PM |
Cheapest Month Mar |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Jul - Sep |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:55AM | Arrival Time 06:30PM | Duration 17h35 | Departure days Mon, Sat, Sun | Cheapest price $87 |
Operator Greyhound | Departure Time 01:25AM | Arrival Time 10:30PM | Duration 21h05 | Departure days Thu | Cheapest price $222 |
Operator Greyhound | Departure Time 01:45AM | Arrival Time 09:40PM | Duration 19h55 | Departure days Mon, Sat, Sun | Cheapest price $86 |
Operator Greyhound | Departure Time 02:25AM | Arrival Time 11:30PM | Duration 21h05 | Departure days Wed, Fri, Sat | Cheapest price $97 |
Operator FlixBus | Departure Time 01:50PM | Arrival Time 12:45PM | Duration 22h55 | Departure days Mon, Sat, Sun | Cheapest price $85 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 06:30PM | Duration 22h20 | Departure days Mon, Sat, Sun | Cheapest price $86 |
Operator Greyhound | Departure Time 09:45PM | Arrival Time 09:40PM | Duration 23h55 | Departure days Mon, Sat | Cheapest price $86 |
The table below shows live departures for Wilmington, DE to Charleston, SC buses for today, Wednesday, August 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:25 AM Wilmington, DE | 21h05 | 10:30 PM Charleston, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
Find answers to the most common questions about traveling from Wilmington, DE to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

Most Wilmington, DE to Charleston, SC buses use the Wilmington, Amtrak Station @ ML King-French to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Wilmington, DE and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
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