Des Moines, IA to Harrisburg, PA bus with Burlington Trailways

Sat, Mar 21
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Burlington Trailways
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2,000+ travel companies
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The cheapest and fastest buses from Des Moines, IA to Harrisburg, PA

Showing times and prices for Mar 22

Cheapest price

$223

Average price

$223

Fastest journey

1 d 2 h 50 m

Average duration

1 d 2 h 50 m

Buses per day

1

Distance

1410 km

Cheap tickets

The best way to find a cheap bus ticket from Des Moines, IA to Harrisburg, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Des Moines, IA to Harrisburg, PA will cost around $223 if you buy it on the day, but the cheapest tickets can be found for only $223.

Fast buses

It's difficult to get from Des Moines, IA to Harrisburg, PA without transferring at least once.

Greyhound USA
09:20AM26h50
Des Moines, IA
12:10PMHarrisburg, PA
$2231One-way
1 transfer

Travel Information

Compare bus and flight for Des Moines, IA to Harrisburg, PA

Omio recommends booking the flight as it is the most popular option from Des Moines, IA to Harrisburg, PA among Omio's users. If you are prioritising price take the bus with prices starting from $125. For those with little time consider booking a flight which can get you there in 11h 24m. The ticket price range depends on the travel mode: a bus costs an average of $125, and a flight costs an average of $443.

Distance: 876 miles (1410 km)

Compare bus with

Bus
Most popular
Flight

$125

Average price

Cheapest

$517

Average price

25h 20m

Average total duration

24h 50m

Onboard

+

30m

Additional time*

14h 24m

Average total duration

Fastest

11h 24m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Live departures

Des Moines, IA to Harrisburg, PA bus times

The table below shows live departures for Des Moines, IA to Harrisburg, PA buses for tomorrow, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.

Last updated at 2:18 PM
ProviderDepartsDurationArrivesTransfers
Tickets
greyhound9:20 AM Des Moines, IA
26h50
12:10 PM Harrisburg, PA1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Des Moines, IA to Harrisburg, PA by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
Mar 22
Mon
Mar 23
Tue
Mar 24
Wed
Mar 25
Thu
Mar 26
Fri
Mar 27
Sat
Mar 28

Journey information

Overview: Bus from Des Moines, IA to Harrisburg, PA

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Buses from Des Moines, IA to Harrisburg, PA run on average 2 times per day, taking around 24h 50m. Cheap bus tickets for this journey start at $125 (€101) if you book in advance.

The earliest bus runs at 00:20, the last at 23:20. The fastest bus covers the 876 miles (1410 km) distance in 23h 50m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
876 miles (1410 km)
Average bus duration
24h 50m
Cheapest ticket price
$125 (€101)
Buses per day
2
Fastest bus
23h 50m
First bus
00:20
Last bus
23:20
Cheapest month
Jan
Cheapest day
Fri
High season
Jan - Mar
Low season
Apr - Jun
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Burlington Trailways from Des Moines, IA to Harrisburg, PAYou can travel by bus between Des Moines, IA to Harrisburg, PA with Burlington Trailways for as low as $125 (€101). When you search for schedules and tickets, Omio will show you the best journey

Burlington Trailways

Luggage & cancellation policy
Average Duration
26h 30m
Cheapest Price
$288 (€233)
Burlington Trailways frequency
1 a day

FAQs: Bus from Des Moines, IA to Harrisburg, PA

Find answers to the most common questions about traveling from Des Moines, IA to Harrisburg, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Des Moines, IA to Harrisburg, PA can start from as little as $125 (€101) when you book in advance. The average bus ticket price for Des Moines, IA to Harrisburg, PA is $125 (€101) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Des Moines, IA to Harrisburg, PA is 23h 50m to travel the 876 miles (1410 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Des Moines, IA to Harrisburg, PA leaves at 12:20 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Des Moines, IA to Harrisburg, PA leaves at 11:20 PM.
There are 2 buses a day from Des Moines, IA to Harrisburg, PA which require at least one change with Burlington Trailways. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Des Moines, IA to Harrisburg, PA, you can count on Burlington Trailways for the best way to get you to Harrisburg, PA. You can also check all possible bus companies who offer a service between Des Moines, IA and Harrisburg, PA and compare the amenities they offer before buying a bus ticket.
A trip to Harrisburg, PA from Des Moines, IA is worth doing but not as a day trip with a journey time of 23h 50m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Des Moines, IA to Harrisburg, PA is January.
It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and Harrisburg, PA including taking a bus and flight.
No, the bus from Des Moines, IA to Harrisburg, PA has no accessibility options.
No, there are no bathrooms on board the bus from Des Moines, IA to Harrisburg, PA.
Some of the most interesting sights to explore in Harrisburg, PA are:
  • Pennsylvania State Capitol, an architectural marvel featuring a grand dome and exquisite interior murals
  • National Civil War Museum, a comprehensive museum offering insights into the American Civil War with extensive exhibits
  • The State Museum of Pennsylvania, showcasing the state's history, art, and natural sciences through diverse collections
  • Fort Hunter Mansion and Park, a historic site with preserved buildings and beautiful grounds reflecting 18th and 19th-century life
  • Wildwood Park, a nature preserve offering trails and a nature center for wildlife observation and environmental education.
The best things to do in Harrisburg, PA include:
  • City Island, a recreational area featuring sports facilities, walking trails, and riverboat cruises
  • Whitaker Center for Science and the Arts, a venue offering interactive science exhibits and live performances
  • Broad Street Market, one of the oldest continuously operating farmers' markets in the country, offering diverse local foods and goods
  • Susquehanna Art Museum, presenting contemporary art exhibitions and educational programs
  • Riverfront Park, ideal for walking, biking, and enjoying views of the Susquehanna River.
No, bikes are not allowed on board the bus from Des Moines, IA to Harrisburg, PA.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Des Moines, IA to Harrisburg, PA.
No, luggage for the bus from Des Moines, IA to Harrisburg, PA needs to be booked in addition.
No, there are no additional luggage options for the bus from Des Moines, IA to Harrisburg, PA.
Unfortunately, pets are not allowed on the bus from Des Moines, IA to Harrisburg, PA.
No, there are no USB plugs on board the bus from Des Moines, IA to Harrisburg, PA.
No, there is no WiFi on board the bus from Des Moines, IA to Harrisburg, PA.

popular bus stations

Popular bus stations from Des Moines, IA to Harrisburg, PA

Des Moines
Harrisburg
Harrisburg, Market St (Bus Station)
information

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