- Must visit
National Civil Rights Museum
Major museum at the former Lorraine Motel, tracing the American civil rights movement and the legacy of Dr. Martin Luther King Jr. One of Memphis’s most important cultural sites.
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The cheapest and fastest buses from Des Moines, IA to Memphis, TN
Showing times and prices for Jun 19
Cheapest price
$159
Average price
$171
Fastest journey
14 h 10 m
Average duration
17 h 33 m
Buses per day
2
Distance
781 km
Cheap tickets
The best way to find a cheap bus ticket from Des Moines, IA to Memphis, TN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Des Moines, IA to Memphis, TN will cost around $171 if you buy it on the day, but the cheapest tickets can be found for only $159.
Fast buses
It's difficult to get from Des Moines, IA to Memphis, TN without transferring at least once.
· 4:20 PM14h10Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA6:30 AMMemphis, Airways Transit Center$1591One-way1 transfer- · · 4:35 AM20h55Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA1:30 AMMemphis, Airways Transit Center$1841One-way2 transfers
- · 4:20 PM14h10Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA6:30 AMMemphis, Airways Transit Center$1591One-way1 transfer
- · · 4:35 AM20h55Des Moines, E Euclid Ave (Clark Lift Of Des Moines, Inc.), IA1:30 AMMemphis, Airways Transit Center$1841One-way2 transfers
Des Moines, IA to Memphis, TN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:35AM | Arrival Time 01:30AM | Duration 20h55 | Departure days Mon, Fri, Sat | Cheapest price $134 |
Operator Greyhound | Departure Time 04:20PM | Arrival Time 06:30AM | Duration 14h10 | Departure days Mon, Fri, Sat | Cheapest price $127 |
Operator Jefferson Lines | Departure Time 11:45PM | Arrival Time 05:00PM | Duration 17h15 | Departure days Tue, Wed, Thu | Cheapest price $237 |
Live departures
Des Moines, IA to Memphis, TN bus times
The table below shows live departures for Des Moines, IA to Memphis, TN buses for today, Thursday, June 18. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 11:45 PM Des Moines, IA | 17h15 | 5:00 PM Memphis, TN | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Des Moines, IA to Memphis, TN by bus
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Journey information
Overview: Bus from Des Moines, IA to Memphis, TN
USAUSA
Buses from Des Moines, IA to Memphis, TN run on average 2 times per day, taking around 17h 15m. Cheap bus tickets for this journey start at $237 (€194) if you book in advance.
The earliest bus runs at 04:55, the last at 18:40. The fastest bus covers the 485 miles (781 km) distance in 17h 15m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 485 miles (781 km) |
Average bus duration 17h 15m |
Cheapest ticket price $237 (€194) |
Buses per day 2 |
Fastest bus 17h 15m |
First bus 4:55 AM |
Last bus 6:40 PM |
Cheapest Month Sep |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Jefferson Lines from Des Moines, IA to Memphis, TNYou can travel by bus between Des Moines, IA to Memphis, TN with Jefferson Lines for as low as $237 (€194). When you search for schedules and tickets, Omio will show you the best journey
Jefferson Lines
Luggage & cancellation policy
Average Duration
17h 15m
Cheapest Price
$237 (€194)
Jefferson Lines frequency
1 a day
Complete guide to Memphis
Things to do in Memphis
Discover the best of Memphis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Memphis trip today.
- Must visit
Stax Museum of American Soul Music
Museum on the original Stax Records site, celebrating soul music legends and the label’s deep connection to Memphis. A favorite for music fans and culture-focused visitors.
- Recommended
Memphis Rock 'n' Soul Museum
Smithsonian-affiliated museum telling the story of Memphis music, from rural roots to the rise of rock and soul. Compact, well-curated, and easy to pair with Beale Street.
- Must visit
Beale Street
Memphis’s most famous entertainment street, known for live music, neon signs, and deep blues heritage. A core stop for first-time visitors day or night.
- Recommended
South Main Historic Arts District
Walkable downtown district with galleries, restored buildings, murals, and a more local feel than Beale Street. Popular for photography and casual exploring.
- Recommended
Shelby Farms Park
Huge urban park with lakes, trails, open space, and outdoor recreation. One of the best green spaces in Memphis for families, walkers, and cyclists.
- Gluten-free
Memphis-Style Pork Ribs
Slow-smoked pork ribs, usually served dry-rubbed or lightly sauced. They are one of Memphis’s signature barbecue specialties.
Pulled Pork Barbecue Sandwich
Chopped or pulled smoked pork piled on a bun, often topped with slaw. It is a classic everyday Memphis barbecue order.
- Gluten-free
Dry Rub Barbecue
Memphis barbecue famous for a spice rub applied before smoking rather than heavy sauce. It highlights the city’s pit-smoking tradition.
Flight Restaurant and Wine Bar
Established upscale downtown restaurant offering tasting flights, refined New American dishes, and a polished atmosphere.
The Bar-B-Q Shop
Beloved local barbecue spot celebrated for ribs, pulled pork, and barbecue spaghetti in an unfussy traditional atmosphere.
Central BBQ
Popular long-running barbecue restaurant known for Memphis-style ribs, pulled pork, and smoked wings in a lively casual setting.
United States Dollar
Moderate by U.S. standards. Hotels and dining are often cheaper than in larger coastal cities, though tourist areas and live music venues cost more.
Average meal costs
- Budget
- USD 10-15 for fast food or a casual lunch.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 60-120+ per person at upscale restaurants.
- Coffee
- USD 3-6 for drip coffee or a latte.
Tipping culture
Tip 18-20% at restaurants; 20%+ for great service. Tip USD 1-2 per drink at bars, round up taxis or tip 10-15%, and tip hotel staff and valet.
FAQs: Bus from Des Moines, IA to Memphis, TN
Find answers to the most common questions about traveling from Des Moines, IA to Memphis, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Memphis, TN, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Des Moines, IA to Memphis, TN can start from as little as $237 (€194) when you book in advance. The average bus ticket price for Des Moines, IA to Memphis, TN is $237 (€194) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Des Moines, IA to Memphis, TN is 17h 15m to travel the 485 miles (781 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Des Moines, IA to Memphis, TN leaves at 4:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Des Moines, IA to Memphis, TN leaves at 6:40 PM.
There are 2 buses a day from Des Moines, IA to Memphis, TN which require at least one change with Jefferson Lines. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Des Moines, IA to Memphis, TN, you can count on Jefferson Lines for the best way to get you to Memphis, TN. You can also check all possible bus companies who offer a service between Des Moines, IA and Memphis, TN and compare the amenities they offer before buying a bus ticket.
A trip to Memphis, TN from Des Moines, IA is worth doing but not as a day trip with a journey time of 17h 15m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Des Moines, IA to Memphis, TN is September.
Yes, you can take a bus between Des Moines, IA and Memphis, TN.
No, there are no bathrooms on board the bus from Des Moines, IA to Memphis, TN.
No, the bus from Des Moines, IA to Memphis, TN has no accessibility options.
Some of the most interesting sights to explore in Memphis, TN are:
- Graceland, the iconic mansion and former home of Elvis Presley offering tours and exhibits
- Beale Street, a historic street known for its vibrant nightlife and live music venues
- National Civil Rights Museum, a museum located at the former Lorraine Motel, site of Martin Luther King Jr.'s assassination, exploring the history of the civil rights movement
- Memphis Zoo, a popular attraction featuring a wide variety of animal exhibits and conservation programs
- Stax Museum of American Soul Music, a museum celebrating the legacy of soul music and its artists.
The best things to do in Memphis, TN include:
- Visit Shelby Farms Park, one of the largest urban parks in America, offering outdoor activities like biking and paddle boating
- Explore the Memphis Botanic Garden, featuring beautiful themed gardens and seasonal events
- Take a riverboat cruise on the Mississippi River for scenic views and historical insights
- Enjoy a live performance at the Orpheum Theatre, a historic venue hosting Broadway shows and concerts
- Discover the vibrant art scene at the Dixon Gallery and Gardens, showcasing fine art and horticulture.
No, bikes are not allowed on board the bus from Des Moines, IA to Memphis, TN.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Des Moines, IA to Memphis, TN.
No, luggage for the bus from Des Moines, IA to Memphis, TN needs to be booked in addition.
No, there are no additional luggage options for the bus from Des Moines, IA to Memphis, TN.
Unfortunately, pets are not allowed on the bus from Des Moines, IA to Memphis, TN.
No, there are no USB plugs on board the bus from Des Moines, IA to Memphis, TN.
No, there is no WiFi on board the bus from Des Moines, IA to Memphis, TN.
Since neither Des Moines, IA nor Memphis, TN are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Memphis, TN, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like Beale Street and downtown. It's important to avoid walking alone at night in less populated neighborhoods. Common scams include overcharging by unofficial taxi or ride-share drivers and distraction techniques used to steal wallets or phones. Staying aware of surroundings and using reputable transportation services helps ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Des Moines, IA to Memphis, TN
Des Moines
Memphis
Memphis, Airways Transit Center
information
Most popular bus connections from Des Moines, IA
More options for your journey from Des Moines, IA to Memphis, TN
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Most popular buses to and from Memphis, TN and Des Moines, IA
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