Harrisburg, PA to Des Moines, IA bus with FlixBus

Fri, Dec 19
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Itabus
1,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Itabus
1,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

The cheapest and fastest buses from Harrisburg, PA to Des Moines, IA

Showing times and prices for Dec 22

Cheapest price

$261

Average price

$261

Fastest journey

2 d 50 m

Average duration

2 d 50 m

Buses per day

1

Distance

1410 km

Cheap tickets

The best way to find a cheap bus ticket from Harrisburg, PA to Des Moines, IA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Harrisburg, PA to Des Moines, IA will cost around $261 if you buy it on the day, but the cheapest tickets can be found for only $261.

Fast buses

Of the 1 buses that leave Harrisburg, PA for Des Moines, IA on Mon, Dec 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Mon, Dec 22 the direct buses cover the 1410 km distance in an average of 2 d 50 m but if you time it right, some buses will get you there in just 2 d 50 m .

On Mon, Dec 22 the slowest buses will take 2 d 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus
06:45PM48h50
Harrisburg, PA
07:35PMDes Moines, IA
$2611One-way
0 transfers

Live departures

Harrisburg, PA to Des Moines, IA bus times

The table below shows live departures for Harrisburg, PA to Des Moines, IA buses for today, Sunday, December 21. You can also manually refresh the results below to see updated bus journeys.

Last updated at 10:57 AM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus2:00 PM Harrisburg, PA
49h55
3:55 PM Des Moines, IA2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Harrisburg, PA to Des Moines, IA by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Mon
Dec 22
Tue
Dec 23
Wed
Dec 24
Thu
Dec 25
Fri
Dec 26
Sat
Dec 27
Sun
Dec 28

Journey information

Overview: Bus from Harrisburg, PA to Des Moines, IA

USAUSA
USAUSA
Icon of bus

Buses from Harrisburg, PA to Des Moines, IA run on average 2 times per day, taking around 49h 19m. Cheap bus tickets for this journey start at $402 (€322) if you book in advance.

The earliest bus runs at 02:30, the last at 12:25. The fastest bus covers the 876 miles (1410 km) distance in 48h 55m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
876 miles (1410 km)
Average bus duration
49h 19m
Cheapest ticket price
$402 (€322)
Buses per day
2
Fastest bus
48h 55m
First bus
02:30
Last bus
12:25
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus from Harrisburg, PA to Des Moines, IAYou can travel by bus between Harrisburg, PA to Des Moines, IA with FlixBus for as low as $402 (€322). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
48h 50m
Cheapest Price
$261 (€209)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

FAQs: Bus from Harrisburg, PA to Des Moines, IA

Find answers to the most common questions about traveling from Harrisburg, PA to Des Moines, IA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Des Moines, IA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Harrisburg, PA to Des Moines, IA can start from as little as $451 (€362) when you book in advance. The average bus ticket price for Harrisburg, PA to Des Moines, IA is $451 (€362); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The bus time between Harrisburg, PA and Des Moines, IA is on average 48 h 55 min   for the 874 mile (1410 km) long journey, but the time it takes to go between Harrisburg, PA and Des Moines, IA by bus can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from Harrisburg, PA to Des Moines, IA leaves at 4: 35AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Harrisburg, PA to Des Moines, IA leaves at 5: 30AM.
There is 1 bus a day from Harrisburg, PA to Des Moines, IA which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
For the best Harrisburg, PA to Des Moines, IA bus to purchase, you can travel safely and comfortably with FlixBus. However, it's always good to check all possible bus providers with services between Harrisburg, PA and Des Moines, IA to compare what amenities they may offer.
The cheapest month to travel from Harrisburg, PA to Des Moines, IA by bus is November.
You have options as you can travel from Harrisburg, PA to Des Moines, IA 2 different ways: bus or flight.
Yes, the following accessibility options are available when taking the bus from Harrisburg, PA to Des Moines, IA:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Harrisburg, PA to Des Moines, IA for bus company FlixBus.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Whether you can cancel your bus ticket from Harrisburg, PA to Des Moines, IA depends on the bus company:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.

To find the cheapest bus tickets for your trip from Harrisburg, PA to Des Moines, IA, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.

    • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Harrisburg, PA to Des Moines, IA.
    Yes, the following luggage options are included when booking a bus ticket from Harrisburg, PA to Des Moines, IA:
    • FlixBus
      • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
    Yes, the following additional luggage options are available when booking a bus ticket from Harrisburg, PA to Des Moines, IA:
    • FlixBus
      • Additional luggage can be purchased for a fee.
    Yes, you can bring your pet on the bus from Harrisburg, PA to Des Moines, IA. The following conditions apply:
    • FlixBus
      • Small pets in carriers allowed
      • Guide dogs travel for free.
    You can reserve your seat on the bus from Harrisburg, PA to Des Moines, IA with the following bus company: FlixBus
    Yes, there are USB plugs on board the bus from Harrisburg, PA to Des Moines, IA with the following bus company: FlixBus.
    Yes, there is Wifi on board the bus from Harrisburg, PA to Des Moines, IA with the following bus company: FlixBus.

    More options for your journey from Harrisburg, PA to Des Moines, IA

    Here are some other resources that might have the information you need

    Return journeys for buses from Des Moines, IA to Harrisburg, PA
    Tickets and more information for coaches to Harrisburg, PA
    Tickets and more information for coaches to Des Moines, IA

    Most popular buses to and from Des Moines, IA and Harrisburg, PA

    Bus Harrisburg, PA - Boston, MA
    Bus Harrisburg, PA - New York, NY
    Bus Harrisburg, PA - Chicago, IL
    Bus Harrisburg, PA - Washington, DC
    Bus Harrisburg, PA - San Diego, CA
    Bus Harrisburg, PA - Philadelphia, PA
    Bus Harrisburg, PA - Orlando, FL
    Bus Harrisburg, PA - Dallas, TX
    Bus Harrisburg, PA - Atlanta, GA
    Bus Harrisburg, PA - San Francisco, CA
    Bus Harrisburg, PA - Phoenix, AZ
    Bus Harrisburg, PA - Houston, TX
    Bus Harrisburg, PA - Sacramento, CA
    Bus Harrisburg, PA - Tampa, FL
    Bus Harrisburg, PA - Portland, OR
    Bus Harrisburg, PA - Baltimore, MD
    Bus Harrisburg, PA - Newark, NJ
    Bus Harrisburg, PA - New Orleans, LA
    Bus Harrisburg, PA - St. Louis, MO
    Bus Harrisburg, PA - Milwaukee, WI
    Bus Harrisburg, PA - Charlotte, NC
    Bus Harrisburg, PA - Nashville, TN
    Bus New York, NY - Des Moines, IA
    Bus Chicago, IL - Des Moines, IA
    Bus Los Angeles, CA - Des Moines, IA
    Bus Washington, DC - Des Moines, IA
    Bus San Diego, CA - Des Moines, IA
    Bus Philadelphia, PA - Des Moines, IA
    Bus Orlando, FL - Des Moines, IA
    Bus Atlanta, GA - Des Moines, IA
    Bus Seattle, WA - Des Moines, IA
    Bus Houston, TX - Des Moines, IA
    Bus Las Vegas, NV - Des Moines, IA
    Bus Sacramento, CA - Des Moines, IA
    Bus Newark, NJ - Des Moines, IA
    Bus Denver, CO - Des Moines, IA
    Bus St. Louis, MO - Des Moines, IA
    Bus Milwaukee, WI - Des Moines, IA
    Bus Raleigh, NC - Des Moines, IA
    Bus Jacksonville, FL - Des Moines, IA
    Bus Columbus, OH - Des Moines, IA
    Bus Detroit, MI - Des Moines, IA
    Bus Toronto, ON - Des Moines, IA
    Bus Minneapolis, MN - Des Moines, IA
    HomeBusesBuses in USABus tickets to Des Moines, IAHarrisburg, PA to Des Moines, IA bus

    The Omio App Makes Travel Planning Easy

    We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

    ios-badge
    android-badge
    Hand With Phone