- Must visit
The State Museum of Pennsylvania
Major regional museum with American art, natural history, and science exhibits. It is Harrisburg's best-known museum and a strong all-ages visit.
Cheapest price
$62
Average price
$64
Fastest journey
11 h 15 m
Average duration
13 h 27 m
Buses per day
3
Distance
563 km
The best way to find a cheap bus ticket from Detroit, MI to Harrisburg, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Detroit, MI to Harrisburg, PA will cost around $64 if you buy it on the day, but the cheapest tickets can be found for only $62.
Of the 3 buses that leave Detroit, MI for Harrisburg, PA on Wed, Aug 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Aug 05 the direct buses cover the 563 km distance in an average of 13 h 27 m but if you time it right, some buses will get you there in just 11 h 15 m .
On Wed, Aug 05 the slowest buses will take 15 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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· · Omio recommends booking the bus as it is the most popular option from Detroit, MI to Harrisburg, PA among Omio's users. If you are prioritising price take the bus with prices starting from $77. For those with little time consider booking a flight which can get you there in 7h 47m. The ticket price range depends on the travel mode: a bus costs an average of $77, and a flight costs an average of $522.
Distance: 349 miles (563 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$110 Average price Cheapest | $573 Average price | $233 Average price | $193 Average price (fuel + tolls) |
12h 27m Average total duration 11h 57m Onboard + 30m Additional time* | 10h 47m Average total duration Fastest 7h 47m Onboard + 3h 0m Additional time* | 15h 55m Average total duration 15h 25m Onboard + 30m Additional time* | 7h 21m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Detroit, MI to Harrisburg, PA:
A bus is $123 less than a train for this route with tickets for a train from Detroit, MI to Harrisburg, PA costing on average $233.
A bus is $464 less than a flight for this route with tickets for a flight from Detroit, MI to Harrisburg, PA costing on average $573.
Other travel options to Harrisburg, PA take longer:
Bus takes on average 11h 57m.
Train takes on average 15h 25m.
Tickets start at around $110 compared to roughly $193 in fuel and tolls — a saving of about $83. The journey takes 11h 57m versus 7h 21m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Greyhound.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 07:15AM | Arrival Time 11:05PM | Duration 15h50 | Departure days Everyday | Cheapest price $63 |
Operator Greyhound | Departure Time 11:05AM | Arrival Time 12:30AM | Duration 13h25 | Departure days Fri | Cheapest price $82 |
Operator Greyhound | Departure Time 11:15AM | Arrival Time 12:30AM | Duration 13h15 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $67 |
Operator Greyhound | Departure Time 11:00PM | Arrival Time 10:15AM | Duration 11h15 | Departure days Everyday | Cheapest price $62 |
The table below shows live departures for Detroit, MI to Harrisburg, PA buses for today, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 11:00 PM Detroit, Greyhound Terminal | 11h35 | 10:35 AM Harrisburg, Market St (Bus Station), PA | 1 transfer | |
| Wednesday, August 5 | |||||
· · | 7:15 AM Detroit, Greyhound Terminal | 15h50 | 11:05 PM Harrisburg, Market St (Bus Station), PA | 2 transfers | |
![]() | 11:15 AM Detroit, Greyhound Terminal | 13h15 | 12:30 AM Harrisburg, Market St (Bus Station), PA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Detroit, MI to Harrisburg, PA run on average 4 times per day, taking around 11h 57m. Cheap bus tickets for this journey start at $77 if you book in advance.
There are 1 buses per day. The earliest bus runs at 02:30, the last at 23:00. The fastest bus covers the 349 miles (563 km) distance in 11h 15m.
Distance 349 miles (563 km) |
Average bus duration 11h 57m |
Cheapest ticket price $77 |
Buses per day 4 |
Direct buses 1 |
Fastest bus 11h 15m |
First bus 2:30 AM |
Last bus 11:00 PM |
Cheapest Month Apr |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Mon |
Least Busy Day Mon |
Discover the best of Harrisburg, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Harrisburg, PA trip today.
Major regional museum with American art, natural history, and science exhibits. It is Harrisburg's best-known museum and a strong all-ages visit.
National Civil War museum with broad exhibits on soldiers, civilians, and the war's legacy. It is one of the city's most important history stops.
Museum at Fort Hunter highlighting local river history, mansion life, and the Susquehanna landscape. A quieter favorite with a scenic setting.
Riverfront promenade and park system with skyline views, paths, and event spaces. It is one of the most pleasant walks in central Harrisburg.
Car-free island in the Susquehanna with walking paths, recreation, and broad water views. A classic local escape close to downtown.
Victorian neighborhood known for colorful homes, local shops, and a creative atmosphere. It is ideal for strolling and seeing everyday Harrisburg charm.
Pennsylvania Dutch chicken pot pie is a rich stew with square noodles, chicken, and vegetables. It is a regional comfort food common around Harrisburg.
Shoofly pie is a classic Pennsylvania Dutch dessert made with molasses crumb filling. Its deep sweetness makes it a traditional local bakery staple.
Whoopie pie features two soft chocolate cake rounds with creamy filling. It is a beloved Amish and Pennsylvania Dutch treat found across the region.
Long-running local favorite serving creative American dishes and seafood in a comfortable, polished neighborhood setting.
Historic market with many established local vendors for Pennsylvania Dutch baked goods, pretzels, sandwiches, and regional specialties in a lively setting.
Popular casual tavern and brewery pouring local beer with pub fare. It is well known for a relaxed atmosphere and central location.
Moderate for US state capitals; hotels and dining are usually below major East Coast cities, while transit needs and limited cheap tourist areas can raise daily costs.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if service is provided.
Find answers to the most common questions about traveling from Detroit, MI to Harrisburg, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.

Most Detroit, MI to Harrisburg, PA buses use the Detroit, Greyhound Terminal to Harrisburg, Market St (Bus Station) station pair, with some services arriving at Harrisburg, Chestnut Street / South 4th Street. Use this guide to compare Detroit, MI and Harrisburg, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Detroit, Greyhound Terminal is 1 km from Detroit city centre. Public transport options include:
Detroit, Greyhound Terminal has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Fast food and coffee shops available.
Free Wi-Fi available in waiting areas. ATMs are aTM located near the main entrance.
Ticket office support is available at Detroit, Greyhound Terminal.
Available at Detroit, Greyhound Terminal: Parking, Taxis, WC.
Accessibility facilities are available at Detroit, Greyhound Terminal: Wheelchair accessible facilities available.
Harrisburg, Market St (Bus Station) is 1 km from Harrisburg city centre. Public transport options include:
Harrisburg, Market St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi inside the station. ATMs are available at Harrisburg, Market St (Bus Station).
Ticket office support is available at Harrisburg, Market St (Bus Station).
Available at Harrisburg, Market St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Harrisburg, Market St (Bus Station): Wheelchair accessible with ramps.
Harrisburg, Chestnut Street / South 4th Street is 1 km from Harrisburg city centre. Public transport options include:
Harrisburg, Chestnut Street / South 4th Street has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Harrisburg, Chestnut Street / South 4th Street. ATMs are available at Harrisburg, Chestnut Street / South 4th Street.
Ticket office support is available at Harrisburg, Chestnut Street / South 4th Street.
Available at Harrisburg, Chestnut Street / South 4th Street: Parking, Taxis, WC.
Accessibility facilities are available at Harrisburg, Chestnut Street / South 4th Street: Accessible by wheelchair via main entrance.
Here are some other resources that might have the information you need