- Must visit
The State Museum of Pennsylvania
Major regional museum with American art, natural history, and science exhibits. It is Harrisburg's best-known museum and a strong all-ages visit.
Cheapest price on Sep 20
kr446
Average ticket price on Sep 20
kr448
Fastest journey on Sep 20
11 h 15 m
Average journey duration on Sep 20
13 h 27 m
Buses on Sep 20
3
Distance
563 km
The best way to find a cheap bus ticket from Detroit, MI to Harrisburg, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Detroit, MI to Harrisburg, PA will cost around kr448 if you buy it on the day, but the cheapest tickets can be found for only kr446.
On Sun, Sep 20, we found 3 buses from Detroit, MI to Harrisburg, PA, including 1 direct services.
On Sun, Sep 20 the direct buses cover the 563 km distance in an average of 13 h 27 m but if you time it right, some buses will get you there in just 11 h 15 m .
On Sun, Sep 20 the slowest buses will take 15 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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· · Omio recommends booking the bus as it is the most popular option from Detroit, MI to Harrisburg, PA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of kr601 For those with little time, consider booking a flight, which has an average total journey time of 5h 46m. Average ticket prices depend on the travel mode: a bus costs an average of kr601, while a flight costs an average of kr4744.
Distance: 349 miles (563 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
kr601 Average price Cheapest | kr4744 Average price | kr1261 Average price (fuel + tolls) | |
12h 2m Average total duration 11h 32m Onboard + 30m Additional time* | 5h 46m Average total duration Fastest 3h 46m Onboard + 2h 0m Additional time* | 7h 21m Average total duration (door-to-door) | |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Detroit, MI to Harrisburg, PA:
A bus is kr4143 less than a flight for this route with tickets for a flight from Detroit, MI to Harrisburg, PA costing on average kr4744.
Other travel options to Harrisburg, PA take longer:
Bus takes on average 11h 32m.
Tickets start at around kr601 compared to roughly kr1261 in fuel and tolls — a saving of about kr660. The journey takes 11h 32m versus 7h 21m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Greyhound.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 07:15AM | Arrival Time 11:05PM | Duration 15h50 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price kr334 |
Operator Greyhound | Departure Time 11:05AM | Arrival Time 12:20AM | Duration 13h15 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price kr398 |
Operator Greyhound | Departure Time 03:55PM | Arrival Time 04:30AM | Duration 12h35 | Departure days Fri | Cheapest price kr501 |
Operator Greyhound | Departure Time 11:00PM | Arrival Time 10:15AM | Duration 11h15 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price kr326 |
The table below shows live departures for Detroit, MI to Harrisburg, PA buses for today, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · | 7:15 AM Detroit, Greyhound Terminal | 16h00 | 11:15 PM Harrisburg, Market St (Bus Station), PA | 2 transfers | |
![]() | 11:05 AM Detroit, Greyhound Terminal | 13h05 | 12:10 AM Harrisburg, Market St (Bus Station), PA | 0 transfersDirect | |
· | 11:00 PM Detroit, Greyhound Terminal | 11h25 | 10:25 AM Harrisburg, Market St (Bus Station), PA | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Detroit, MI to Harrisburg, PA run on average 3 times per day, taking around 11h 32m. Cheap bus tickets for this journey start at kr358 if you book in advance.
There are 1 buses per day. The earliest bus runs at 02:30, the last at 23:00. The fastest bus covers the 349 miles (563 km) distance in 9h 45m.
Distance 349 miles (563 km) |
Average bus duration 11h 32m |
Cheapest ticket price kr358 |
Buses per day 3 |
Direct buses 1 |
Fastest bus 9h 45m |
First bus 2:30 AM |
Last bus 11:00 PM |
Cheapest Month Apr |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Thu |
Least Busy Day Thu |
Discover the best of Harrisburg, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Harrisburg, PA trip today.
Major regional museum with American art, natural history, and science exhibits. It is Harrisburg's best-known museum and a strong all-ages visit.
National Civil War museum with broad exhibits on soldiers, civilians, and the war's legacy. It is one of the city's most important history stops.
Museum at Fort Hunter highlighting local river history, mansion life, and the Susquehanna landscape. A quieter favorite with a scenic setting.
Riverfront promenade and park system with skyline views, paths, and event spaces. It is one of the most pleasant walks in central Harrisburg.
Car-free island in the Susquehanna with walking paths, recreation, and broad water views. A classic local escape close to downtown.
Victorian neighborhood known for colorful homes, local shops, and a creative atmosphere. It is ideal for strolling and seeing everyday Harrisburg charm.
Pennsylvania Dutch chicken pot pie is a rich stew with square noodles, chicken, and vegetables. It is a regional comfort food common around Harrisburg.
Shoofly pie is a classic Pennsylvania Dutch dessert made with molasses crumb filling. Its deep sweetness makes it a traditional local bakery staple.
Whoopie pie features two soft chocolate cake rounds with creamy filling. It is a beloved Amish and Pennsylvania Dutch treat found across the region.
Long-running local favorite serving creative American dishes and seafood in a comfortable, polished neighborhood setting.
Historic market with many established local vendors for Pennsylvania Dutch baked goods, pretzels, sandwiches, and regional specialties in a lively setting.
Popular casual tavern and brewery pouring local beer with pub fare. It is well known for a relaxed atmosphere and central location.
Moderate for US state capitals; hotels and dining are usually below major East Coast cities, while transit needs and limited cheap tourist areas can raise daily costs.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if service is provided.
Find answers to the most common questions about traveling from Detroit, MI to Harrisburg, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.

Most Detroit, MI to Harrisburg, PA buses use the Detroit, Greyhound Terminal to Harrisburg, Market St (Bus Station) station pair. Use this guide to compare Detroit, MI and Harrisburg, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Detroit, Greyhound Terminal is 1 km from Detroit city centre. Public transport options include:
Detroit, Greyhound Terminal has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Fast food and coffee shops available.
Free Wi-Fi available in waiting areas. ATMs are aTM located near the main entrance.
Ticket office support is available at Detroit, Greyhound Terminal.
Available at Detroit, Greyhound Terminal: Parking, Taxis, WC.
Accessibility facilities are available at Detroit, Greyhound Terminal: Wheelchair accessible facilities available.
Harrisburg, Market St (Bus Station) is 1 km from Harrisburg city centre. Public transport options include:
Harrisburg, Market St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi inside the station. ATMs are available at Harrisburg, Market St (Bus Station).
Ticket office support is available at Harrisburg, Market St (Bus Station).
Available at Harrisburg, Market St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Harrisburg, Market St (Bus Station): Wheelchair accessible with ramps.
Here are some other resources that might have the information you need