- Must visit
The State Museum Of Pennsylvania
The Commonwealth’s flagship history museum with exhibits on archaeology, industry, Civil War history, natural history, and fine art. A strong first stop for understanding Pennsylvania’s story.
Cheapest price
$110
Average price
$112
Fastest journey
11 h 10 m
Average duration
11 h 40 m
Buses per day
3
Distance
563 km
The best way to find a cheap bus ticket from Detroit, MI to Harrisburg, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Detroit, MI to Harrisburg, PA will cost around $112 if you buy it on the day, but the cheapest tickets can be found for only $110.
Of the 3 buses that leave Detroit, MI for Harrisburg, PA on Sun, Jun 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct buses cover the 563 km distance in an average of 11 h 40 m but if you time it right, some buses will get you there in just 11 h 10 m .
On Sun, Jun 21 the slowest buses will take 12 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Omio recommends booking the bus as it is the most popular option from Detroit, MI to Harrisburg, PA among Omio's users. If you are prioritising price take the bus with prices starting from $77. For those with little time consider booking a flight which can get you there in 7h 47m. The ticket price range depends on the travel mode: a bus costs an average of $77, and a flight costs an average of $520.
Distance: 349 miles (563 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$109 Average price Cheapest | $232 Average price | $571 Average price | $192 Average price (fuel + tolls) |
12h 27m Average total duration 11h 57m Onboard + 30m Additional time* | 15h 55m Average total duration 15h 25m Onboard + 30m Additional time* | 10h 47m Average total duration Fastest 7h 47m Onboard + 3h 0m Additional time* | 7h 21m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Detroit, MI to Harrisburg, PA:
A bus is $123 (€100) less than a train for this route with tickets for a train from Detroit, MI to Harrisburg, PA costing on average $232 (€190).
A bus is $462 (€378) less than a flight for this route with tickets for a flight from Detroit, MI to Harrisburg, PA costing on average $571 (€467).
Other travel options to Harrisburg, PA take longer:
Bus takes on average 11h 57m.
Train takes on average 15h 25m.
Tickets start at around $109 (€89) compared to roughly $192 (€157) in fuel and tolls — a saving of about $83 (€68). The journey takes 11h 57m versus 7h 21m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Greyhound.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:00AM | Arrival Time 02:15PM | Duration 11h15 | Departure days Tue, Wed | Cheapest price $129 |
Operator Greyhound | Departure Time 07:15AM | Arrival Time 11:05PM | Duration 15h50 | Departure days Wed, Thu, Fri | Cheapest price $87 |
Operator Greyhound | Departure Time 11:15AM | Arrival Time 12:30AM | Duration 13h15 | Departure days Wed, Thu, Fri | Cheapest price $72 |
Operator Greyhound USA | Departure Time 11:55AM | Arrival Time 11:05PM | Duration 11h10 | Departure days Sun | Cheapest price $110 |
Operator Greyhound | Departure Time 03:55PM | Arrival Time 04:30AM | Duration 12h35 | Departure days Tue, Sat | Cheapest price $88 |
Operator Greyhound USA | Departure Time 11:00PM | Arrival Time 10:15AM | Duration 11h15 | Departure days Wed, Thu, Fri, Sun | Cheapest price $95 |
The table below shows live departures for Detroit, MI to Harrisburg, PA buses for tomorrow, Sunday, June 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:55 AM Detroit, MI | 11h10 | 11:05 PM Harrisburg, PA | 1 transfer | |
![]() | 11:55 AM Detroit, MI | 12h35 | 12:30 AM Harrisburg, PA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Detroit, MI to Harrisburg, PA run on average 4 times per day, taking around 11h 57m. Cheap bus tickets for this journey start at $77 (€63) if you book in advance.
There are 1 buses per day. The earliest bus runs at 02:30, the last at 23:00. The fastest bus covers the 349 miles (563 km) distance in 11h 15m.
Distance 349 miles (563 km) |
Average bus duration 11h 57m |
Cheapest ticket price $77 (€63) |
Buses per day 4 |
Direct buses 1 |
Fastest bus 11h 15m |
First bus 2:30 AM |
Last bus 11:00 PM |
Cheapest Month Apr |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Mon |
Least Busy Day Mon |
Discover the best of Harrisburg — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Harrisburg trip today.
The Commonwealth’s flagship history museum with exhibits on archaeology, industry, Civil War history, natural history, and fine art. A strong first stop for understanding Pennsylvania’s story.
Major museum interpreting the American Civil War from multiple perspectives, with extensive artifacts, documents, and rotating exhibitions. One of Harrisburg’s best-known cultural attractions.
Contemporary art museum featuring regional, national, and international artists in a modern downtown space. A good choice for travelers interested in current exhibitions and local creative culture.
Linear park along the Susquehanna River with walking paths, public art, and excellent skyline views. It is one of Harrisburg’s most pleasant and photogenic places for a stroll.
Recreational island in the Susquehanna offering river views, trails, and open space between downtown and the west shore. Popular for relaxed walks and classic Harrisburg scenery.
The ceremonial and governmental heart of Harrisburg, with landscaped grounds, monuments, and some of the city’s best architecture. A practical and scenic area for sightseeing.
A regional staple made with broad noodles simmered in rich chicken broth, often with chicken and vegetables. It is a classic Central Pennsylvania comfort dish.
A smoky, tangy cured beef sausage from nearby Lebanon County, traditionally sliced for sandwiches or cheese boards. It is one of the area's best-known local meats.
A Pennsylvania Dutch dessert pie with a molasses filling and crumb topping. It is strongly associated with the region's baking traditions.
A well-regarded fine dining spot offering contemporary American cuisine, craft cocktails, and a polished but comfortable atmosphere.
A popular restaurant, brewery, and arts space known for seasonal Pennsylvania ingredients, house beer, and a lively industrial-chic atmosphere.
An established downtown Italian restaurant and wine bar known for brick-oven pizzas, handmade pasta, and an intimate urban setting.
Generally moderate for U.S. travel. Meals and coffee are reasonable, while hotels can rise during events or peak government travel periods.
Tip 18-20% at restaurants for table service, 15-20% for taxis, USD 1-2 per drink at bars, and a few dollars for hotel staff. Tipping is not expected at most fast-food counters.
Find answers to the most common questions about traveling from Detroit, MI to Harrisburg, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.

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