The cheapest and fastest buses from Greenville, SC to Tampa, FL
Cheapest price
$188
Average price
$188
Fastest journey
21 h 10 m
Average duration
21 h 10 m
Buses per day
1
Distance
768 km
The best way to find a cheap bus ticket from Greenville, SC to Tampa, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Tampa, FL will cost around $188 if you buy it on the day, but the cheapest tickets can be found for only $188.
Of the 1 buses that leave Greenville, SC for Tampa, FL on Tue, Dec 23, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Dec 23 the direct buses cover the 768 km distance in an average of 21 h 10 m but if you time it right, some buses will get you there in just 21 h 10 m .
On Tue, Dec 23 the slowest buses will take 21 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for Greenville, SC to Tampa, FL
Omio recommends booking the flight as it is the most popular option from Greenville, SC to Tampa, FL among Omio's users. If you are prioritising price take the bus with prices starting from €69. For those with little time consider booking a flight which can get you there in 1h 37m. The ticket price range depends on the travel mode: a bus costs an average of €69, and a train costs an average of €122.
Distance: 477 miles (768 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€93 Average price Cheapest | €207 Average price | €281 Average price |
12h 55m Average total duration 12h 25m Onboard + 30m Additional time* | 4h 37m Average total duration Fastest 1h 37m Onboard + 3h 0m Additional time* | 28h 1m Average total duration 27h 31m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Greenville, SC to Tampa, FL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 23
Dec 24
Dec 25
Dec 26
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Dec 28
Dec 29
Journey information
Overview: Bus from Greenville, SC to Tampa, FL
Buses from Greenville, SC to Tampa, FL run on average 5 times per day, taking around 12h 25m. Cheap bus tickets for this journey start at $86 (€69) but you can travel from only $55 (€44) by flight.
The earliest bus runs at 00:40, the last at 22:35. The fastest bus covers the 477 miles (768 km) distance in 15h 45m.
Distance 477 miles (768 km) |
Average bus duration 12h 25m |
Cheapest ticket price $86 (€69) |
Buses per day 5 |
Fastest bus 15h 45m |
First bus 00:40 |
Last bus 22:35 |
Bus providers: Greyhound from Greenville, SC to Tampa, FLYou can travel by bus between Greenville, SC to Tampa, FL with Greyhound for as low as $55 (€44). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Greenville, SC to Tampa, FL
Find answers to the most common questions about traveling from Greenville, SC to Tampa, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Tampa, FL, this guide helps you travel smarter and with confidence.

- Busch Gardens Tampa Bay, a renowned theme park offering thrilling rides and animal encounters
- The Florida Aquarium, a popular attraction featuring marine life exhibits and interactive experiences
- Tampa Riverwalk, a scenic waterfront path with parks, museums, and dining options
- Ybor City, a historic district known for its vibrant nightlife and Cuban culture
- Tampa Museum of Art, showcasing contemporary and classical art in a modern architectural setting.
- Visit the historic Henry B. Plant Museum, housed in a former luxury hotel with exhibits on the Gilded Age
- Explore the vibrant Hyde Park Village, offering shopping, dining, and entertainment
- Attend a Tampa Bay Buccaneers game at Raymond James Stadium for an exciting sports experience
- Take a boat tour of Tampa Bay for stunning views and wildlife sightings
- Enjoy a day at the beautiful Clearwater Beach, just a short drive from Tampa.
To find the cheapest bus tickets for your trip from Greenville, SC to Tampa, FL, follow these tips:
Start your search now and compare ticket prices to find the best deal!
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Popular bus stations from Greenville, SC to Tampa, FL
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