- Must visit
Tampa Museum of Art
Modern and classical art museum on the Riverwalk, known for its contemporary exhibitions and prominent downtown setting.
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The cheapest and fastest buses from Greenville, SC to Tampa, FL
Showing times and prices for Jun 21
Cheapest price
$114
Average price
$131
Fastest journey
16 h 25 m
Average duration
17 h 29 m
Buses per day
6
Distance
768 km
Cheap tickets
The best way to find a cheap bus ticket from Greenville, SC to Tampa, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Tampa, FL will cost around $131 if you buy it on the day, but the cheapest tickets can be found for only $114.
Fast buses
It's difficult to get from Greenville, SC to Tampa, FL without transferring at least 2 times.
FlixBus · FlixBus · FlixBus · FlixBus9:35 PM24h50Greenville, Woodruff Rd ("Raceway" gas station), SC10:25 PMTampa, Marion Transit Center$1141One-way3 transfers- FlixBus · FlixBus+
2:45 PM18h30Greenville, Woodruff Rd ("Raceway" gas station), SC9:15 AMTampa, USF Holly Drive (Central Plant), FL$1251One-way2 transfers - FlixBus · FlixBus+2:45 PM18h55Greenville, Woodruff Rd ("Raceway" gas station), SC9:40 AMTampa, Marion Transit Center$1251One-way2 transfers
- FlixBus · FlixBus · FlixBus1:20 PM16h40Greenville, Woodruff Rd ("Raceway" gas station), SC6:00 AMTampa, Marion Transit Center$1401One-way2 transfers
- FlixBus · FlixBus+8:20 PM16h25Greenville, Woodruff Rd ("Raceway" gas station), SC12:45 PMTampa, USF Holly Drive (Central Plant), FL$1401One-way2 transfers
- FlixBus · FlixBus+8:20 PM16h25Greenville, Woodruff Rd ("Raceway" gas station), SC12:45 PMTampa, USF Holly Drive (Central Plant), FL$1401One-way2 transfers
- FlixBus · FlixBus · FlixBus1:20 PM16h40Greenville, Woodruff Rd ("Raceway" gas station), SC6:00 AMTampa, Marion Transit Center$1401One-way2 transfers
- FlixBus · FlixBus+8:20 PM16h55Greenville, Woodruff Rd ("Raceway" gas station), SC1:15 PMTampa, Marion Transit Center$1421One-way2 transfers
- FlixBus · FlixBus+2:45 PM18h30Greenville, Woodruff Rd ("Raceway" gas station), SC9:15 AMTampa, USF Holly Drive (Central Plant), FL$1251One-way2 transfers
- FlixBus · FlixBus+2:45 PM18h55Greenville, Woodruff Rd ("Raceway" gas station), SC9:40 AMTampa, Marion Transit Center$1251One-way2 transfers
Travel Information
Compare bus, flight, and train for Greenville, SC to Tampa, FL
Omio recommends booking the train as it is the most popular option from Greenville, SC to Tampa, FL among Omio's users. If you are prioritising price take the bus with prices starting from $91. For those with little time consider booking a flight which can get you there in 1h 37m. The ticket price range depends on the travel mode: a bus costs an average of $91, and a flight costs an average of $95.
Distance: 477 miles (768 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$166 Average price Cheapest | $245 Average price | $287 Average price | $114 Average price (fuel + tolls) |
13h 8m Average total duration 12h 38m Onboard + 30m Additional time* | 24h 20m Average total duration 23h 50m Onboard + 30m Additional time* | 4h 37m Average total duration Fastest 1h 37m Onboard + 3h 0m Additional time* | 8h 42m Average total duration (door-to-door) |
Most popular bus company |  Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Greenville, SC to Tampa, FL is a bus with an average price of $166 (€136).
This is compared to other travel options from Greenville, SC to Tampa, FL:
A bus is $78 (€64) less than a train for this route with tickets for a train from Greenville, SC to Tampa, FL costing on average $245 (€200).
A bus is $120 (€99) less than a flight for this route with tickets for a flight from Greenville, SC to Tampa, FL costing on average $287 (€235).
The fastest way to travel from Greenville, SC to Tampa, FL is by flight with an average journey time of 1h 37m.
Other travel options to Tampa, FL take longer:
Bus takes on average 12h 38m.
Train takes on average 23h 50m.
It's helpful to compare your options as there are 3 ways to travel between Greenville, SC and Tampa, FL including taking a bus, flight, and train.
We recommend using the train as it is the most popular way to get from Greenville, SC to Tampa, FL among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Greenville, SC to Tampa, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:00AM | Arrival Time 03:25AM | Duration 24h25 | Departure days Tue | Cheapest price $142 |
Operator FlixBus | Departure Time 11:15AM | Arrival Time 06:00AM | Duration 18h45 | Departure days Wed | Cheapest price $119 |
Operator FlixBus | Departure Time 01:20PM | Arrival Time 06:00AM | Duration 16h40 | Departure days Tue, Thu, Fri, Sat, Sun | Cheapest price $111 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 09:40AM | Duration 18h55 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $100 |
Operator FlixBus | Departure Time 08:20PM | Arrival Time 12:45PM | Duration 16h25 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $119 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 10:25PM | Duration 24h50 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $106 |
Operator FlixBus | Departure Time 09:45PM | Arrival Time 01:30PM | Duration 15h45 | Departure days Mon | Cheapest price $153 |
Live departures
Greenville, SC to Tampa, FL bus times
The table below shows live departures for Greenville, SC to Tampa, FL buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| +FlixBus · FlixBus | 8:20 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 16h55 | 1:15 PM Tampa, Marion Transit Center | 2 transfers | |
| +FlixBus · FlixBus | 8:20 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 16h25 | 12:45 PM Tampa, USF Holly Drive (Central Plant), FL | 2 transfers | |
| FlixBus · FlixBus · FlixBus · FlixBus | 9:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 24h50 | 10:25 PM Tampa, Marion Transit Center | 3 transfers | |
| Sunday, June 21 | |||||
| FlixBus · FlixBus · FlixBus | 1:20 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 16h40 | 6:00 AM Tampa, Marion Transit Center | 2 transfers | |
| FlixBus · FlixBus+ | 2:45 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 18h30 | 9:15 AM Tampa, USF Holly Drive (Central Plant), FL | 2 transfers | |
| FlixBus · FlixBus+ | 2:45 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 18h55 | 9:40 AM Tampa, Marion Transit Center | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Greenville, SC to Tampa, FL by bus, flight, or train
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Greenville, SC to Tampa, FL buses with Omio?
FlixBus as well as Greyhound offer buses services from Greenville, SC to Tampa, FL.
Omio is an official ticket reseller for all your travel options from Greenville, SC to Tampa, FL.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Greenville, SC to Tampa, FL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, flight and train to ensure you get the best deal for traveling from Greenville, SC to Tampa, FL.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from Greenville, SC to Tampa, FL.
- Multiple modes of transport: Omio allows you to compare travel options including bus, flight and train to find the ideal travel option from Greenville, SC to Tampa, FL.
Journey information
Overview: Bus from Greenville, SC to Tampa, FL
USAUSA
Buses from Greenville, SC to Tampa, FL run on average 6 times per day, taking around 12h 38m. Cheap bus tickets for this journey start at $91 (€75) if you book in advance.
The earliest bus runs at 06:20, the last at 22:35. The fastest bus covers the 477 miles (768 km) distance in 15h 45m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 477 miles (768 km) |
Average bus duration 12h 38m |
Cheapest ticket price $91 (€75) |
Buses per day 6 |
Fastest bus 15h 45m |
First bus 6:20 AM |
Last bus 10:35 PM |
Cheapest Month Jan |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Oct - Dec |
Best time to book 77 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus, Greyhound from Greenville, SC to Tampa, FLYou can travel by bus between Greenville, SC to Tampa, FL with FlixBus, Greyhound for as low as $91 (€75). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
15h 45m
Cheapest Price
$91 (€75)
FlixBus frequency
5 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
25h 55m
Cheapest Price
$154 (€126)
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Tampa
Things to do in Tampa
Discover the best of Tampa — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Tampa trip today.
- Must visit
The Dalí Museum
World-famous Salvador Dalí museum across the bay in St. Petersburg, frequently visited from Tampa for its iconic collection and architecture.
- Recommended
Henry B. Plant Museum
Historic museum inside the former Tampa Bay Hotel, showcasing Gilded Age architecture and Tampa history.
- Must visit
Tampa Riverwalk
Signature waterfront promenade linking museums, parks, and public art, and one of the city's most popular walking areas.
- Must visit
Ybor City
Historic neighborhood famous for brick streets, cigar heritage, nightlife, and distinctive cultural character.
- Must visit
Bayshore Boulevard
Scenic waterfront boulevard popular for walking, running, and skyline views along Hillsborough Bay.
Cuban Sandwich
Tampa’s signature sandwich, traditionally layered with Cuban bread, roast pork, ham, salami, Swiss cheese, pickles, and mustard, then pressed hot. The salami reflects the city’s Italian influence in Y
Deviled Crab
A classic Ybor City snack made with spiced crab meat mixed with breadcrumbs, formed into a shell-like shape, breaded, and fried. It reflects Tampa’s cigar-factory immigrant history and is one of the c
Grouper Sandwich
A Florida Gulf Coast favorite often found in Tampa, featuring fresh local grouper grilled, blackened, or fried on a bun. It is especially popular for showcasing the region’s seafood.
Bern's Steak House
Iconic fine-dining destination famous for dry-aged steaks, an extensive wine collection, and classic Tampa special-occasion dining.
Columbia Restaurant
Historic Ybor City institution known for Spanish-Cuban cuisine, the 1905 Salad, and flamenco performances in a grand old-world setting.
Ulele
Popular riverfront restaurant serving Florida-inspired dishes, charbroiled oysters, and native-inspired flavors in a lively upscale-casual atmosphere.
United States Dollar
Moderate for U.S. travelers. Dining and transport are manageable, while hotels rise in peak season and waterfront areas.
Average meal costs
- Budget
- USD 10-18 for a casual meal.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 75+ per person before drinks.
- Coffee
- USD 4-6 for a coffee.
Tipping culture
Tip 18-20% at restaurants. USD 1-2 per drink at bars, round up taxis, and tip hotel staff USD 2-5. Tips are expected for table service.
FAQs: Bus from Greenville, SC to Tampa, FL
Find answers to the most common questions about traveling from Greenville, SC to Tampa, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Tampa, FL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Greenville, SC to Tampa, FL can start from as little as $91 (€75) when you book in advance. The average bus ticket price for Greenville, SC to Tampa, FL is $166 (€136) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Greenville, SC to Tampa, FL is 15h 45m to travel the 477 miles (768 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Greenville, SC to Tampa, FL leaves at 6:20 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Greenville, SC to Tampa, FL leaves at 10:35 PM.
There are 6 buses a day from Greenville, SC to Tampa, FL which require at least one change with FlixBus, Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Greenville, SC to Tampa, FL, you can count on FlixBus, Greyhound for the best way to get you to Tampa, FL. You can also check all possible bus companies who offer a service between Greenville, SC and Tampa, FL and compare the amenities they offer before buying a bus ticket.
A trip to Tampa, FL from Greenville, SC is worth doing but not as a day trip with a journey time of 15h 45m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Greenville, SC to Tampa, FL is January.
It's helpful to compare your options as there are 3 ways to travel between Greenville, SC and Tampa, FL including taking a bus, flight, and train.
Yes, the following accessibility options are available when taking the bus from Greenville, SC to Tampa, FL:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Greenville, SC to Tampa, FL for bus company FlixBus, Greyhound.
Some of the most interesting sights to explore in Tampa, FL are:
- Busch Gardens Tampa Bay, a renowned theme park offering thrilling rides and animal encounters
- The Florida Aquarium, a popular attraction featuring marine life exhibits and interactive experiences
- Tampa Riverwalk, a scenic waterfront path with parks, museums, and dining options
- Ybor City, a historic district known for its vibrant nightlife and Cuban culture
- Tampa Museum of Art, showcasing contemporary and classical art in a modern architectural setting.
The best things to do in Tampa, FL include:
- Visit the historic Henry B. Plant Museum, housed in a former luxury hotel with exhibits on the Gilded Age
- Explore the vibrant Hyde Park Village, offering shopping, dining, and entertainment
- Attend a Tampa Bay Buccaneers game at Raymond James Stadium for an exciting sports experience
- Take a boat tour of Tampa Bay for stunning views and wildlife sightings
- Enjoy a day at the beautiful Clearwater Beach, just a short drive from Tampa.
Whether you can cancel your bus ticket from Greenville, SC to Tampa, FL depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus, Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Greenville, SC to Tampa, FL.
Yes, the following luggage options are included when booking a bus ticket from Greenville, SC to Tampa, FL:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Greenville, SC to Tampa, FL:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Greenville, SC to Tampa, FL. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Greenville, SC to Tampa, FL with the following bus company: FlixBus, Greyhound
Yes, there are USB plugs on board the bus from Greenville, SC to Tampa, FL with the following bus company: FlixBus, Greyhound.
Yes, there is Wifi on board the bus from Greenville, SC to Tampa, FL with the following bus company: FlixBus, Greyhound.
Since neither Greenville, SC nor Tampa, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Greenville, SC to Tampa, FL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Tampa, FL, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and popular tourist spots like Ybor City and downtown. Common scams include overcharging by taxi or rideshare drivers and timeshare presentations that pressure visitors into costly purchases. Staying aware of surroundings and using licensed transportation can help avoid these issues.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Greenville, SC to Tampa, FL
Most Greenville, SC to Tampa, FL buses use the Greenville, Woodruff Rd ("Raceway" gas station) to Tampa, Marion Transit Center station pair, with some services arriving at Tampa, USF Holly Drive (Central Plant). Use this guide to compare Greenville, SC and Tampa, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Greenville
Arrival bus stations in Tampa
Greenville, Woodruff Rd ("Raceway" gas station)
Tampa, Marion Transit Center
City-centre transport
Getting to Tampa, Marion Transit Center from Tampa city centre
Bus1, 5, 19, 30 · 3m · $5 · every ~15 min
Tampa, USF Holly Drive (Central Plant)
City-centre transport
Getting to Tampa, USF Holly Drive (Central Plant) from Tampa city centre
BusFlixBus 2421 · 26m · $1
9, 400 · 1h 3m · $5 · every ~7 min
6 · 1h 9m · $5 · every ~5 min
Most popular bus connections from Greenville, SC
More options for your journey from Greenville, SC to Tampa, FL
Here are some other resources that might have the information you need
Most popular buses to and from Tampa, FL and Greenville, SC
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