The cheapest and fastest buses from Detroit, MI to Greenville, SC
Cheapest price
$96
Average price
$101
Fastest journey
18 h 40 m
Average duration
23 h 44 m
Buses per day
4
Distance
834 km
The best way to find a cheap bus ticket from Detroit, MI to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Detroit, MI to Greenville, SC will cost around $101 if you buy it on the day, but the cheapest tickets can be found for only $96.
It's difficult to get from Detroit, MI to Greenville, SC without transferring at least once.
+
FlixBus+
1:50 PM20h50Detroit, Greyhound Terminal10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$961One-way2 transfers
· 7:55 PM18h40Detroit, Greyhound Terminal2:35 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$961One-way1 transfer
· 7:15 AM20h00Detroit, Greyhound Terminal3:15 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$991One-way1 transfer
· · +
FlixBus11:15 PM35h25Detroit, Greyhound Terminal10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$1141One-way4 transfers
· 7:55 PM18h40Detroit, Greyhound Terminal2:35 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$961One-way1 transfer
· 7:15 AM20h00Detroit, Greyhound Terminal3:15 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$991One-way1 transfer
+
FlixBus+
1:50 PM20h50Detroit, Greyhound Terminal10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$961One-way2 transfers
· · +
FlixBus11:15 PM35h25Detroit, Greyhound Terminal10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$1141One-way4 transfers
Journey information
Overview: Bus from Detroit, MI to Greenville, SC
Buses from Detroit, MI to Greenville, SC run on average 4 times per day, taking around 19h 25m. Cheap bus tickets for this journey start at $103 if you book in advance.
The earliest bus runs at 02:23, the last at 23:45. The fastest bus covers the 518 miles (834 km) distance in 18h 20m.
Distance 518 miles (834 km) |
Average bus duration 19h 25m |
Cheapest ticket price $103 |
Buses per day 4 |
Fastest bus 18h 20m |
First bus 2:23 AM |
Last bus 11:45 PM |
Cheapest Month Sep |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Apr - Jun |
Detroit, MI to Greenville, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 07:15AM | Arrival Time 03:15AM | Duration 20h00 | Departure days Everyday | Cheapest price $97 |
Operator Greyhound | Departure Time 01:50PM | Arrival Time 10:40AM | Duration 20h50 | Departure days Everyday | Cheapest price $96 |
Operator Greyhound | Departure Time 07:55PM | Arrival Time 02:35PM | Duration 18h40 | Departure days Everyday | Cheapest price $96 |
Operator FlixBus | Departure Time 11:15PM | Arrival Time 10:40AM | Duration 35h25 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $96 |
Live departures
Detroit, MI to Greenville, SC bus times
The table below shows live departures for Detroit, MI to Greenville, SC buses for today, Wednesday, August 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· + FlixBus | 1:50 PM Detroit, Greyhound Terminal | 22h10 | 12:00 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 2 transfers | |
· | 7:55 PM Detroit, Greyhound Terminal | 18h40 | 2:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
· · + FlixBus | 11:15 PM Detroit, Greyhound Terminal | 35h25 | 10:40 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 4 transfers | |
| Thursday, August 6 | |||||
· | 7:15 AM Detroit, Greyhound Terminal | 20h00 | 3:15 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Detroit, MI to Greenville, SC buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Detroit, MI to Greenville, SC.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Detroit, MI to Greenville, SC.
Bus providers: Greyhound from Detroit, MI to Greenville, SCYou can travel by bus between Detroit, MI to Greenville, SC with Greyhound for as low as $103. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Detroit, MI to Greenville, SC
Find answers to the most common questions about traveling from Detroit, MI to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Detroit, MI to Greenville, SC
Most Detroit, MI to Greenville, SC buses use the Detroit, Greyhound Terminal to Greenville, Woodruff Rd ("Raceway" gas station) station pair. Use this guide to compare Detroit, MI and Greenville, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Detroit, MI station do buses to Greenville, SC leave from?
Getting to Detroit, Greyhound Terminal from Detroit city centre
Detroit, Greyhound Terminal is 1 km from Detroit city centre. Public transport options include:
Detroit, Greyhound Terminal bus station facilities and services
Detroit, Greyhound Terminal has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Fast food and coffee shops available.
Wi-Fi and ATMs
Free Wi-Fi available in waiting areas. ATMs are aTM located near the main entrance.
Tickets and information
Ticket office support is available at Detroit, Greyhound Terminal.
Parking, taxis and toilets
Available at Detroit, Greyhound Terminal: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Detroit, Greyhound Terminal: Wheelchair accessible facilities available.
Which Greenville, SC station do buses from Detroit, MI arrive at?
Getting to Greenville, Woodruff Rd ("Raceway" gas station) from Greenville city centre
Greenville, Woodruff Rd ("Raceway" gas station) is 8 km from Greenville city centre. Public transport options include:
Greenville, Woodruff Rd ("Raceway" gas station) bus station facilities and services
Greenville, Woodruff Rd ("Raceway" gas station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Limited dining options available in adjacent areas.
Wi-Fi and ATMs
Wi-Fi is available at Greenville, Woodruff Rd ("Raceway" gas station). ATMs are available at Greenville, Woodruff Rd ("Raceway" gas station).
Tickets and information
Ticket office support is available at Greenville, Woodruff Rd ("Raceway" gas station).
Parking, taxis and toilets
Available at Greenville, Woodruff Rd ("Raceway" gas station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Greenville, Woodruff Rd ("Raceway" gas station): Basic access available for persons with disabilities.
Most popular bus connections from Detroit, MI
More options for your journey from Detroit, MI to Greenville, SC
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