- Must visit
California Academy of Sciences
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Cheapest price
$221
Average price
$269
Fastest journey
2 d 23 h 5 m
Average duration
3 d 5 h 23 m
Buses per day
2
Distance
3857 km
The best way to find a cheap bus ticket from Tampa, FL to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Tampa, FL to San Francisco, CA will cost around $269 if you buy it on the day, but the cheapest tickets can be found for only $221.
Of the 2 buses that leave Tampa, FL for San Francisco, CA on Thu, Aug 27, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Aug 27 the direct buses cover the 3857 km distance in an average of 3 d 5 h 23 m but if you time it right, some buses will get you there in just 2 d 23 h 5 m .
On Thu, Aug 27 the slowest buses will take 3 d 11 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the flight as it is the most popular option from Tampa, FL to San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from $170. For those with little time consider booking a flight which can get you there in 7h 46m. The ticket price range depends on the travel mode: a bus costs an average of $170, and a flight costs an average of $222.
Distance: 2396 miles (3857 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$429 Average price Cheapest | $588 Average price | $580 Average price (fuel + tolls) | |
68h 29m Average total duration 67h 59m Onboard + 30m Additional time* | 10h 46m Average total duration Fastest 7h 46m Onboard + 3h 0m Additional time* | 41h 40m Average total duration (door-to-door) | |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Tampa, FL to San Francisco, CA:
A bus is $160 (€129) less than a flight for this route with tickets for a flight from Tampa, FL to San Francisco, CA costing on average $588 (€474).
Other travel options to San Francisco, CA take longer:
Bus takes on average 67h 59m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:35AM | Arrival Time 02:15PM | Duration 83h40 | Departure days Thu | Cheapest price $221 |
Operator Greyhound | Departure Time 11:10AM | Arrival Time 08:45AM | Duration 72h35 | Departure days Sun | Cheapest price $202 |
Operator Greyhound | Departure Time 03:10PM | Arrival Time 02:15PM | Duration 71h05 | Departure days Mon, Wed, Thu | Cheapest price $317 |
Operator Greyhound | Departure Time 04:00PM | Arrival Time 05:55PM | Duration 76h55 | Departure days Sun | Cheapest price $256 |
Operator Greyhound | Departure Time 04:10PM | Arrival Time 03:15PM | Duration 71h05 | Departure days Sat | Cheapest price $162 |
Operator Greyhound | Departure Time 04:35PM | Arrival Time 08:50PM | Duration 79h15 | Departure days Sun | Cheapest price $258 |
Operator Greyhound | Departure Time 09:15PM | Arrival Time 12:35AM | Duration 75h20 | Departure days Fri, Sat | Cheapest price $239 |
Operator Greyhound | Departure Time 09:30PM | Arrival Time 10:05PM | Duration 75h35 | Departure days Sun | Cheapest price $197 |
Operator Greyhound | Departure Time 10:25PM | Arrival Time 02:05AM | Duration 75h40 | Departure days Sat, Sun | Cheapest price $243 |
Operator Greyhound | Departure Time 10:35PM | Arrival Time 08:45AM | Duration 85h10 | Departure days Sun | Cheapest price $244 |
Operator Greyhound | Departure Time 10:55PM | Arrival Time 07:05AM | Duration 80h10 | Departure days Tue | Cheapest price $511 |
The table below shows live departures for Tampa, FL to San Francisco, CA buses for today, Tuesday, August 25. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:55 PM Tampa, FL | 80h10 | 7:05 AM San Francisco, CA | 0 transfersDirect | |
| Wednesday, August 26 | |||||
![]() | 2:35 AM Tampa, FL | 83h40 | 2:15 PM San Francisco, CA | 0 transfersDirect | |
![]() | 3:10 PM Tampa, FL | 71h05 | 2:15 PM San Francisco, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Tampa, FL to San Francisco, CA run on average 7 times per day, taking around 67h 59m. Cheap bus tickets for this journey start at $170 (€136) if you book in advance.
The earliest bus runs at 06:10, the last at 23:50. The fastest bus covers the 2396 miles (3857 km) distance in 64h 34m.
Distance 2396 miles (3857 km) |
Average bus duration 67h 59m |
Cheapest ticket price $170 (€136) |
Buses per day 7 |
Fastest bus 64h 34m |
First bus 6:10 AM |
Last bus 11:50 PM |
Cheapest Month Jun |
Cheapest Day Fri |
High Season Apr - Jun |
Low Season Oct - Dec |
Best time to book 14 days |
Discover the best of San Francisco, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco, CA trip today.
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Major fine arts museum in Golden Gate Park with American art, textiles, and a panoramic tower. A classic cultural highlight.
Leading modern and contemporary art museum with landmark architecture and strong global collections. Essential for art-focused visitors.
Large urban park with gardens, lakes, museums, and trails. It is a must for relaxing, walking, and seeing several major attractions.
Steeply curving block lined with flowers and grand homes. This famous street offers classic photos and a quintessential San Francisco scene.
Popular waterfront promenade with bay views, piers, and ferries. Great for walking, people-watching, and connecting to nearby sights.
A crusty loaf with a tangy flavor shaped by the city’s historic wild yeast culture. It is one of San Francisco’s most iconic foods.
Fresh local Dungeness crab, often cracked and served simply or in cioppino. It is a Bay Area seasonal specialty tied to the fishing waterfront.
A tomato-based seafood stew created by Italian American fishermen in North Beach. It is a classic San Francisco dish built from the day’s catch.
Celebrated fine dining destination known for inventive tasting menus and polished service in an elegant, intimate setting.
Historic North Beach seafood house famous for cioppino, crab, and old-school San Francisco waterfront charm.
Legendary Mission taqueria known for large Mission-style burritos and a lively, no-frills local atmosphere.
Very high hotel, dining, and transport costs make San Francisco pricier than most US cities and many major tourist destinations.
Tip 18-20% at restaurants, 15-20% for taxis, and round up or tip $1 at cafes for good service.
Find answers to the most common questions about traveling from Tampa, FL to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

Most Tampa, FL to San Francisco, CA buses use the Tampa, Marion Transit Center to San Francisco, Transit Center Bay 29 station pair, with some services arriving at San Francisco, Townsend Street / 5th Street. Use this guide to compare Tampa, FL and San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Tampa, Marion Transit Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Tampa, Marion Transit Center. ATMs are available at Tampa, Marion Transit Center.
Ticket office support is available at Tampa, Marion Transit Center.
Available at Tampa, Marion Transit Center: Parking, Taxis, WC.
Accessibility facilities are available at Tampa, Marion Transit Center: Wheelchair accessible with ramps.
Tampa, USF Holly Drive (Central Plant) is 13 km from Tampa city centre. Public transport options include:
Tampa, USF Holly Drive (Central Plant) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Tampa, USF Holly Drive (Central Plant). ATMs are available at Tampa, USF Holly Drive (Central Plant).
Ticket office support is available at Tampa, USF Holly Drive (Central Plant).
Available at Tampa, USF Holly Drive (Central Plant): Parking, Taxis, WC.
Accessibility facilities are available at Tampa, USF Holly Drive (Central Plant): Wheelchair accessible facilities.
San Francisco, Transit Center Bay 29 is 2 km from San Francisco city centre. Public transport options include:
San Francisco, Transit Center Bay 29 has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Francisco, Transit Center Bay 29. ATMs are available at San Francisco, Transit Center Bay 29.
Ticket office support is available at San Francisco, Transit Center Bay 29.
Available at San Francisco, Transit Center Bay 29: Parking, Taxis, WC.
Accessibility facilities are available at San Francisco, Transit Center Bay 29: Wheelchair accessible areas present.
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