- Must visit
San Francisco Museum of Modern Art
Major modern and contemporary art museum with an internationally important collection and a striking SoMa building.
Cheapest price
$326
Average price
$326
Fastest journey
2 d 23 h 5 m
Average duration
2 d 23 h 5 m
Buses per day
1
Distance
3857 km
The best way to find a cheap bus ticket from Tampa, FL to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Tampa, FL to San Francisco, CA will cost around $326 if you buy it on the day, but the cheapest tickets can be found for only $326.
Of the 1 buses that leave Tampa, FL for San Francisco, CA on Thu, May 28, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, May 28 the direct buses cover the 3857 km distance in an average of 2 d 23 h 5 m but if you time it right, some buses will get you there in just 2 d 23 h 5 m .
On Thu, May 28 the slowest buses will take 2 d 23 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the flight as it is the most popular option from Tampa, FL to San Francisco, CA among Omio's users. If you are prioritising price take the flight with prices starting from $132. For those with little time consider booking a flight which can get you there in 5h 46m. The ticket price range depends on the travel mode: a flight costs an average of $132, and a train costs an average of $292.
Distance: 2396 miles (3857 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$324 Average price | $294 Average price Cheapest | $947 Average price | $570 Average price (fuel + tolls) |
75h 10m Average total duration 74h 40m Onboard + 30m Additional time* | 8h 46m Average total duration Fastest 5h 46m Onboard + 3h 0m Additional time* | 100h 26m Average total duration 99h 56m Onboard + 30m Additional time* | 41h 40m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Tampa, FL to San Francisco, CA:
A flight is $30 (€24) less than a bus for this route with tickets for a bus from Tampa, FL to San Francisco, CA costing on average $324 (€261).
A flight is $653 (€526) less than a train for this route with tickets for a train from Tampa, FL to San Francisco, CA costing on average $947 (€763).
Other travel options to San Francisco, CA take longer:
Bus takes on average 74h 40m.
Train takes on average 99h 56m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 06:20AM | Arrival Time 11:05AM | Duration 79h45 | Departure days Wed | Cheapest price $224 |
Operator Greyhound | Departure Time 11:10AM | Arrival Time 07:15AM | Duration 71h05 | Departure days Mon, Wed | Cheapest price $207 |
Operator Greyhound | Departure Time 03:10PM | Arrival Time 02:15PM | Duration 71h05 | Departure days Thu, Sun | Cheapest price $241 |
Operator Greyhound | Departure Time 04:10PM | Arrival Time 03:15PM | Duration 71h05 | Departure days Sat | Cheapest price $162 |
Operator Greyhound | Departure Time 09:15PM | Arrival Time 12:50AM | Duration 75h35 | Departure days Fri, Sat | Cheapest price $239 |
Operator Greyhound | Departure Time 10:10PM | Arrival Time 11:05AM | Duration 87h55 | Departure days Mon, Wed | Cheapest price $230 |
Operator Greyhound | Departure Time 10:25PM | Arrival Time 02:05AM | Duration 75h40 | Departure days Sat | Cheapest price $622 |
Operator Greyhound | Departure Time 10:35PM | Arrival Time 11:05AM | Duration 87h30 | Departure days Mon, Wed | Cheapest price $230 |
Operator Greyhound | Departure Time 10:55PM | Arrival Time 07:05AM | Duration 80h10 | Departure days Tue | Cheapest price $510 |
The table below shows live departures for Tampa, FL to San Francisco, CA buses for today, Wednesday, May 27. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · · | 11:10 AM Tampa, Marion Transit Center | 71h05 | 7:15 AM San Francisco, Transit Center Bay 29 | 5 transfers | |
FlixBus+ · · | 10:10 PM Tampa, USF Holly Drive (Central Plant), FL | 87h55 | 11:05 AM San Francisco, Townsend Street / 5th Street, CA | 5 transfers | |
FlixBus+ · · | 10:10 PM Tampa, USF Holly Drive (Central Plant), FL | 84h05 | 7:15 AM San Francisco, Transit Center Bay 29 | 4 transfers | |
FlixBus+ · · | 10:35 PM Tampa, Marion Transit Center | 87h30 | 11:05 AM San Francisco, Townsend Street / 5th Street, CA | 5 transfers | |
FlixBus+ · · | 10:35 PM Tampa, Marion Transit Center | 83h40 | 7:15 AM San Francisco, Transit Center Bay 29 | 4 transfers |
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Tampa, FL to San Francisco, CA run on average 9 times per day, taking around 74h 40m. Cheap bus tickets for this journey start at $162 (€131) but you can travel from only $132 (€106) by flight.
The earliest bus runs at 06:10, the last at 23:50. The fastest bus covers the 2396 miles (3857 km) distance in 71h 5m.
Distance 2396 miles (3857 km) |
Average bus duration 74h 40m |
Cheapest ticket price $162 (€131) |
Buses per day 9 |
Fastest bus 71h 5m |
First bus 6:10 AM |
Last bus 11:50 PM |
Cheapest Month Jun |
Cheapest Day Fri |
High Season Apr - Jun |
Low Season Jul - Sep |
Best time to book 14 days |
Discover the best of San Francisco — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco trip today.
Major modern and contemporary art museum with an internationally important collection and a striking SoMa building.
Hands-on science and perception museum on the Embarcadero, especially popular for interactive exhibits and bay views.
Large natural history and science museum with aquarium, planetarium, and rainforest dome in Golden Gate Park.
Expansive urban park with gardens, lakes, museums, trails, and some of the city's best walking and cycling space.
One of North America's oldest and most vibrant Chinatowns, packed with temples, gates, markets, and side streets.
Dramatic coastal walking area with cliffs, cypress-lined trails, Golden Gate views, and Sutro Baths ruins nearby.
A tomato-based seafood stew created by Italian immigrant fishermen in San Francisco. It typically includes crab, clams, mussels, shrimp, and fish, and is one of the city’s signature dishes.
San Francisco is famous for its tangy sourdough, shaped by local wild yeast cultures. It is a historic staple often served as a loaf, toast, or bread bowl.
A large foil-wrapped burrito associated with the Mission District, packed with rice, beans, meat or other fillings, salsa, and extras. It is one of the city’s most influential casual foods.
A Mission District institution celebrated for outstanding Mission-style burritos and tacos. Lively, casual, and widely regarded as one of the city’s essential eats.
A legendary seafood counter famous for ultra-fresh oysters, crab, and seafood cocktails. Casual, iconic, and one of the city’s best-known classic stops.
A popular restaurant serving Asian fusion dishes with bold flavors in a cozy setting. Well known for garlic noodles and seafood-focused plates.
San Francisco is one of the priciest U.S. cities. Hotels, dining, and parking are costly, though casual food options exist.
Tip 18-20% at restaurants; 20%+ for excellent service. Bars: USD 1-2 per drink. Taxis/rideshares: 10-15%. Hotel staff: USD 2-5. Not expected at fast food.
Find answers to the most common questions about traveling from Tampa, FL to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

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