- Must visit
San Diego Museum of Art
Major Balboa Park museum with works from Spanish old masters to modern art, plus strong regional and international exhibitions.
Omio recommends booking the bus as it is the most popular option from Tampa, FL to San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from $162. For those with little time consider booking a flight which can get you there in 5h 24m. The ticket price range depends on the travel mode: a bus costs an average of $162, and a train costs an average of $647.
Distance: 2085 miles (3357 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$256 Average price Cheapest | $288 Average price | $665 Average price | $484 Average price (fuel + tolls) |
63h 25m Average total duration 62h 55m Onboard + 30m Additional time* | 8h 24m Average total duration Fastest 5h 24m Onboard + 3h 0m Additional time* | 102h 8m Average total duration 101h 38m Onboard + 30m Additional time* | 34h 48m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Tampa, FL to San Diego, CA:
A bus is $32 (€26) less than a flight for this route with tickets for a flight from Tampa, FL to San Diego, CA costing on average $288 (€237).
A bus is $409 (€337) less than a train for this route with tickets for a train from Tampa, FL to San Diego, CA costing on average $665 (€548).
Other travel options to San Diego, CA take longer:
Bus takes on average 62h 55m.
Train takes on average 101h 38m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:50AM | Arrival Time 09:10PM | Duration 91h20 | Departure days Mon | Cheapest price $289 |
Operator Greyhound | Departure Time 03:35AM | Arrival Time 02:20AM | Duration 70h45 | Departure days Wed | Cheapest price $280 |
Operator Greyhound | Departure Time 10:20AM | Arrival Time 05:45AM | Duration 67h25 | Departure days Mon, Tue, Sun | Cheapest price $259 |
Operator Greyhound | Departure Time 11:20AM | Arrival Time 06:45AM | Duration 67h25 | Departure days Tue, Sun | Cheapest price $162 |
The table below shows live departures for Tampa, FL to San Diego, CA buses for today, Tuesday, July 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:20 AM Tampa, FL | 67h25 | 5:45 AM San Diego, CA | 0 transfersDirect | |
![]() | 11:20 AM Tampa, FL | 67h25 | 6:45 AM San Diego, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Tampa, FL to San Diego, CA run on average 17 times per day, taking around 62h 55m. Cheap bus tickets for this journey start at $162 (€133) but you can travel from only $121 (€99) by flight.
The earliest bus runs at 06:00, the last at 22:35. The fastest bus covers the 2085 miles (3357 km) distance in 62h 25m.
Distance 2085 miles (3357 km) |
Average bus duration 62h 55m |
Cheapest ticket price $162 (€133) |
Buses per day 17 |
Fastest bus 62h 25m |
First bus 6:00 AM |
Last bus 10:35 PM |
Cheapest Month Nov |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Oct - Dec |
Best time to book 28 days |
Discover the best of San Diego — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Diego trip today.
Major Balboa Park museum with works from Spanish old masters to modern art, plus strong regional and international exhibitions.
Acclaimed contemporary art museum in La Jolla featuring oceanfront settings, modern works, and rotating global exhibitions.
Museum aboard a historic aircraft carrier with restored aircraft, naval exhibits, and immersive views of life at sea.
Balboa Park is San Diego's grand cultural park, packed with gardens, architecture, museums, and walkable plazas worth lingering in.
Historic Gaslamp Quarter offers Victorian-era streets, nightlife energy, and preserved downtown architecture for an atmospheric walk.
Dramatic seaside cliffs and walking paths in La Jolla, famous for waves, sea lions, and sweeping Pacific views.
A San Diego staple: grilled fish in a soft tortilla with cabbage, crema, and salsa. Popularized by Baja influence and coastal seafood culture.
French fries, carne asada, cheese, guacamole, and crema wrapped in a flour tortilla. A late-night local favorite born in San Diego taquerias.
Fresh local sea urchin served raw, prized for its rich, buttery taste. It reflects San Diego's access to Pacific seafood and sushi culture.
Celebrated sushi restaurant specializing in omakase and pristine seafood, including uni. Intimate, polished, and highly respected by locals.
Iconic casual seafood counter known for fish tacos, smoked fish, and harbor views. A classic stop for San Diego's Baja-inspired seafood style.
Refined fine-dining restaurant showcasing local seafood and seasonal California ingredients. Elegant room with one of the city's strongest reputations.
San Diego is pricey for US travel, with higher hotel rates, dining, and parking than many cities, though casual food and buses stay manageable.
Tip 18-20% at restaurants, 15-20% for taxis or rideshares, and $1-2 for coffee drinks or small cafe orders.
Find answers to the most common questions about traveling from Tampa, FL to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

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