Indianapolis, IN to Greenville, SC bus

Sun, Feb 01
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FlixBus
Costa Verde
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
FlixBus
Costa Verde
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
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Journey information

Overview: Bus from Indianapolis, IN to Greenville, SC

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Take a bus from Indianapolis, IN to Greenville, SC and enjoy the approximately 397 miles (640 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 03:15, the last at 23:30.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
397 miles (640 km)
Buses per day
6
First bus
03:15
Last bus
23:30
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Indianapolis, IN to Greenville, SC

Find answers to the most common questions about traveling from Indianapolis, IN to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

FAQs
The earliest bus from Indianapolis, IN to Greenville, SC leaves at 3:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Indianapolis, IN to Greenville, SC leaves at 11:30 PM.
The cheapest month for a bus from Indianapolis, IN to Greenville, SC is November.
Yes, you can take a between Indianapolis, IN and Greenville, SC.
No, there are no bathrooms on board the bus from Indianapolis, IN to Greenville, SC.
No, the bus from Indianapolis, IN to Greenville, SC has no accessibility options.
No, bikes are not allowed on board the bus from Indianapolis, IN to Greenville, SC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Indianapolis, IN to Greenville, SC.
No, luggage for the bus from Indianapolis, IN to Greenville, SC needs to be booked in addition.
No, there are no additional luggage options for the bus from Indianapolis, IN to Greenville, SC.
Unfortunately, pets are not allowed on the bus from Indianapolis, IN to Greenville, SC.
No, there are no USB plugs on board the bus from Indianapolis, IN to Greenville, SC.
No, there is no WiFi on board the bus from Indianapolis, IN to Greenville, SC.

popular bus stations

Popular bus stations from Indianapolis, IN to Greenville, SC

Indianapolis
Greenville
The major bus station for departures in Indianapolis is Indianapolis, Illinois St (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Indianapolis, Illinois St (Greyhound Bus Station) for your trip from Indianapolis to Greenville.
Indianapolis, Illinois St (Greyhound Bus Station)
information
Indianapolis, E Washington St / N Delaware St (City/County Building)
information

More options for your journey from Indianapolis, IN to Greenville, SC

Here are some other resources that might have the information you need

Return journeys for buses from Greenville, SC to Indianapolis, IN
Flights from Indianapolis, IN to Greenville, SC
Tickets and more information for coaches to Indianapolis, IN
Tickets and more information for coaches to Greenville, SC

Most popular buses to and from Greenville, SC and Indianapolis, IN

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Bus Indianapolis, IN - New Orleans, LA
Bus Boston, MA - Greenville, SC
Bus New York, NY - Greenville, SC
Bus Chicago, IL - Greenville, SC
Bus Washington, DC - Greenville, SC
Bus Philadelphia, PA - Greenville, SC
Bus Orlando, FL - Greenville, SC
Bus Atlanta, GA - Greenville, SC
Bus Miami, FL - Greenville, SC
Bus Houston, TX - Greenville, SC
Bus Sacramento, CA - Greenville, SC
Bus Tampa, FL - Greenville, SC
Bus Portland, OR - Greenville, SC
Bus Baltimore, MD - Greenville, SC
Bus Newark, NJ - Greenville, SC
Bus Charlotte, NC - Greenville, SC
Bus Nashville, TN - Greenville, SC
Bus Austin, TX - Greenville, SC
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