4.9
4.6The cheapest and fastest buses from Indianapolis, IN to Greenville, SC
Cheapest price on Sep 17
$89
Average ticket price on Sep 17
$91
Fastest journey on Sep 17
14 h 55 m
Average journey duration on Sep 17
16 h 3 m
Buses on Sep 17
5
Distance
640 km
The best way to find a cheap bus ticket from Indianapolis, IN to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Indianapolis, IN to Greenville, SC will cost around $91 if you buy it on the day, but the cheapest tickets can be found for only $89.
It's difficult to get from Indianapolis, IN to Greenville, SC without transferring at least once.
+
FlixBus4:40 AM16h50Indianapolis, Illinois St (Greyhound Bus Station)9:30 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$891One-way1 transfer- · 4:05 PM14h55Indianapolis, Illinois St (Greyhound Bus Station)7:00 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$891One-way1 transfer
- +FlixBus8:10 PM16h25Indianapolis, Illinois St (Greyhound Bus Station)12:35 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$891One-way1 transfer
- FlixBus+6:35 PM16h05Indianapolis, E Washington St / N Delaware St (City/County Building), IN10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$901One-way1 transfer
- · 11:15 AM16h00Indianapolis, Illinois St (Greyhound Bus Station)3:15 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$961One-way1 transfer
- · 4:05 PM14h55Indianapolis, Illinois St (Greyhound Bus Station)7:00 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$891One-way1 transfer
- · 11:15 AM16h00Indianapolis, Illinois St (Greyhound Bus Station)3:15 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$961One-way1 transfer
- FlixBus+6:35 PM16h05Indianapolis, E Washington St / N Delaware St (City/County Building), IN10:40 AMGreenville, Woodruff Rd ("Raceway" gas station), SC$901One-way1 transfer
- +FlixBus8:10 PM16h25Indianapolis, Illinois St (Greyhound Bus Station)12:35 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$891One-way1 transfer
- +FlixBus4:40 AM16h50Indianapolis, Illinois St (Greyhound Bus Station)9:30 PMGreenville, Woodruff Rd ("Raceway" gas station), SC$891One-way1 transfer
Travel Information
Compare bus and train for Indianapolis, IN to Greenville, SC
Omio recommends booking the train as it is the most popular option from Indianapolis, IN to Greenville, SC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $112 For those with little time, consider booking a bus, which has an average total journey time of 14h 29m. Average ticket prices depend on the travel mode: a bus costs an average of $112, while a train costs an average of $202.
Distance: 397 miles (640 km)
Compare bus with
| Bus | Most popular Train | Driving |
|---|---|---|
$112 Average price Cheapest | $202 Average price | $101 Average price (fuel + tolls) |
14h 29m Average total duration Fastest 13h 59m Onboard + 30m Additional time* | 24h 52m Average total duration 24h 22m Onboard + 30m Additional time* | 10h 6m Average total duration (door-to-door) |
Most popular bus company |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Indianapolis, IN to Greenville, SC:
A bus is $90 less than a train for this route with tickets for a train from Indianapolis, IN to Greenville, SC costing on average $202.
A bus is $455 less than a flight for this route with tickets for a flight from Indianapolis, IN to Greenville, SC costing on average $567.
Other travel options to Greenville, SC take longer:
Bus takes on average 13h 59m.
Train takes on average 24h 22m.
Tickets start at around $112 compared to roughly $101 in fuel and tolls — a saving of about $-11.10. The journey takes 13h 59m versus 10h 6m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Indianapolis, IN to Greenville, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:40AM | Arrival Time 09:30PM | Duration 16h50 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $74 |
Operator Greyhound | Departure Time 11:15AM | Arrival Time 03:15AM | Duration 16h00 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $74 |
Operator Greyhound | Departure Time 04:05PM | Arrival Time 07:00AM | Duration 14h55 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $74 |
Operator FlixBus | Departure Time 06:35PM | Arrival Time 10:40AM | Duration 16h05 | Departure days Mon, Tue, Thu, Fri, Sun | Cheapest price $75 |
Operator Greyhound | Departure Time 08:05PM | Arrival Time 02:35PM | Duration 18h30 | Departure days Mon, Tue | Cheapest price $77 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 12:35PM | Duration 16h25 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $74 |
Operator FlixBus | Departure Time 11:25PM | Arrival Time 12:35PM | Duration 13h10 | Departure days Wed, Fri, Sun | Cheapest price $79 |
Live departures
Indianapolis, IN to Greenville, SC bus times
The table below shows live departures for Indianapolis, IN to Greenville, SC buses for today, Wednesday, September 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| +FlixBus | 8:10 PM Indianapolis, Illinois St (Greyhound Bus Station) | 16h25 | 12:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| FlixBus · FlixBus | 11:25 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 13h10 | 12:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| Thursday, September 17 | |||||
| +FlixBus | 4:40 AM Indianapolis, Illinois St (Greyhound Bus Station) | 16h50 | 9:30 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| · | 11:15 AM Indianapolis, Illinois St (Greyhound Bus Station) | 16h00 | 3:15 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
| · | 4:05 PM Indianapolis, Illinois St (Greyhound Bus Station) | 14h55 | 7:00 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 1 transfer | |
Find all the dates and times for this journey
Why should you book Indianapolis, IN to Greenville, SC buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Indianapolis, IN to Greenville, SC.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and train to ensure you get the best deal for traveling from Indianapolis, IN to Greenville, SC.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Indianapolis, IN to Greenville, SC.
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Indianapolis, IN to Greenville, SC.
Journey information
Overview: Bus from Indianapolis, IN to Greenville, SC
USAUSA
Buses from Indianapolis, IN to Greenville, SC run on average 7 times per day, taking around 13h 59m. Cheap bus tickets for this journey start at $82 if you book in advance.
The earliest bus runs at 03:15, the last at 23:30. The fastest bus covers the 397 miles (640 km) distance in 11h 55m.
Distance 397 miles (640 km) |
Average bus duration 13h 59m |
Cheapest ticket price $82 |
Buses per day 7 |
Fastest bus 11h 55m |
First bus 3:15 AM |
Last bus 11:30 PM |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Oct - Dec |
Bus providers: Greyhound, FlixBus from Indianapolis, IN to Greenville, SCYou can travel by bus between Indianapolis, IN to Greenville, SC with Greyhound, FlixBus for as low as $82. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Indianapolis, IN to Greenville, SC
Find answers to the most common questions about traveling from Indianapolis, IN to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Indianapolis, IN to Greenville, SC
Most Indianapolis, IN to Greenville, SC buses use the Indianapolis, Illinois St (Greyhound Bus Station) to Greenville, Woodruff Rd ("Raceway" gas station) station pair. Use this guide to compare Indianapolis, IN and Greenville, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Indianapolis, IN station do buses to Greenville, SC leave from?
Getting to Indianapolis, Illinois St (Greyhound Bus Station) from Indianapolis city centre
Indianapolis, Illinois St (Greyhound Bus Station) bus station facilities and services
Indianapolis, Illinois St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Fast food outlets are available.
Wi-Fi and ATMs
Free Wi-Fi is available throughout the station. ATMs are aTM is located near the entrance.
Tickets and information
Ticket office support is available at Indianapolis, Illinois St (Greyhound Bus Station).
Parking, taxis and toilets
Available at Indianapolis, Illinois St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Indianapolis, Illinois St (Greyhound Bus Station): The station is wheelchair accessible.
Which Greenville, SC station do buses from Indianapolis, IN arrive at?
Getting to Greenville, Woodruff Rd ("Raceway" gas station) from Greenville city centre
Greenville, Woodruff Rd ("Raceway" gas station) is 8 km from Greenville city centre. Public transport options include:
Greenville, Woodruff Rd ("Raceway" gas station) bus station facilities and services
Greenville, Woodruff Rd ("Raceway" gas station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Limited dining options available in adjacent areas.
Wi-Fi and ATMs
Wi-Fi is available at Greenville, Woodruff Rd ("Raceway" gas station). ATMs are available at Greenville, Woodruff Rd ("Raceway" gas station).
Tickets and information
Ticket office support is available at Greenville, Woodruff Rd ("Raceway" gas station).
Parking, taxis and toilets
Available at Greenville, Woodruff Rd ("Raceway" gas station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Greenville, Woodruff Rd ("Raceway" gas station): Basic access available for persons with disabilities.
Most popular bus connections from Indianapolis, IN
More options for your journey from Indianapolis, IN to Greenville, SC
Here are some other resources that might have the information you need
Most popular buses to and from Greenville, SC and Indianapolis, IN
Most popular bus connections to Greenville, SC
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