Indianapolis, IN to Greenville, SC bus

Mon, Aug 03
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FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
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The cheapest and fastest buses from Indianapolis, IN to Greenville, SC

Showing times and prices for Aug 03

Cheapest price

$90

Average price

$91

Fastest journey

14 h 55 m

Average duration

15 h 45 m

Buses per day

8

Distance

640 km

Cheap tickets

The best way to find a cheap bus ticket from Indianapolis, IN to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Indianapolis, IN to Greenville, SC will cost around $91 if you buy it on the day, but the cheapest tickets can be found for only $90.

Fast buses

It's difficult to get from Indianapolis, IN to Greenville, SC without transferring at least once.

  • Greyhound · ·
    7:55 PM18h40
    Indianapolis, Illinois St (Greyhound Bus Station)
    2:35 PMGreenville, Woodruff Rd ("Raceway" gas station), SC
    $901One-way
    2 transfers
  • FlixBusFlixBus · FlixBus
    11:25 PM16h45
    Indianapolis, E Washington St / N Delaware St (City/County Building), IN
    4:10 PMGreenville, Woodruff Rd ("Raceway" gas station), SC
    $911One-way
    1 transfer
  • Greyhound+FlixBusFlixBus
    4:40 AM16h50
    Indianapolis, Illinois St (Greyhound Bus Station)
    9:30 PMGreenville, Woodruff Rd ("Raceway" gas station), SC
    $911One-way
    1 transfer
  • Greyhound ·
    4:05 PM14h55
    Indianapolis, Illinois St (Greyhound Bus Station)
    7:00 AMGreenville, Woodruff Rd ("Raceway" gas station), SC
    $911One-way
    1 transfer
  • Greyhound+FlixBusFlixBus
    8:10 PM20h00
    Indianapolis, Illinois St (Greyhound Bus Station)
    4:10 PMGreenville, Woodruff Rd ("Raceway" gas station), SC
    $911One-way
    1 transfer

Journey information

Overview: Bus from Indianapolis, IN to Greenville, SC

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Take a bus from Indianapolis, IN to Greenville, SC and enjoy the approximately 397 miles (640 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 03:15, the last at 23:30.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
397 miles (640 km)
Buses per day
12
First bus
3:15 AM
Last bus
11:30 PM
Cheapest Month
May
Cheapest Day
Mon
High Season
Apr - Jun
Low Season
Apr - Jun
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Indianapolis, IN to Greenville, SC Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
04:40AM
Arrival Time
09:30PM
Duration
16h50
Departure days
Everyday
Cheapest price
$88
Operator
Greyhound
Departure Time
11:15AM
Arrival Time
03:15AM
Duration
16h00
Departure days
Everyday
Cheapest price
$86
Operator
Greyhound
Departure Time
04:05PM
Arrival Time
07:00AM
Duration
14h55
Departure days
Everyday
Cheapest price
$84
Operator
Greyhound
Departure Time
04:20PM
Arrival Time
02:35PM
Duration
22h15
Departure days
Wed
Cheapest price
$87
Operator
FlixBus
Departure Time
06:35PM
Arrival Time
10:40AM
Duration
16h05
Departure days
Mon, Tue, Thu, Fri, Sat, Sun
Cheapest price
$86
Operator
FlixBus
Departure Time
07:40PM
Arrival Time
10:40AM
Duration
15h00
Departure days
Mon, Tue, Thu, Fri, Sat, Sun
Cheapest price
$88
Operator
Greyhound
Departure Time
07:55PM
Arrival Time
02:35PM
Duration
18h40
Departure days
Mon, Tue
Cheapest price
$90
Operator
Greyhound
Departure Time
08:10PM
Arrival Time
12:00PM
Duration
15h50
Departure days
Everyday
Cheapest price
$84
Operator
FlixBus
Departure Time
11:25PM
Arrival Time
04:10PM
Duration
16h45
Departure days
Mon, Tue, Wed, Fri, Sat, Sun
Cheapest price
$84

Live departures

Indianapolis, IN to Greenville, SC bus times

The table below shows live departures for Indianapolis, IN to Greenville, SC buses for today, Sunday, August 2. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound · 4:05 PM Indianapolis, Illinois St (Greyhound Bus Station)
14h55
7:00 AM Greenville, Woodruff Rd ("Raceway" gas station), SC1 transfer
FlixBusFlixBus+Greyhound6:35 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN
16h05
10:40 AM Greenville, Woodruff Rd ("Raceway" gas station), SC1 transfer
FlixBusFlixBus+Greyhound · 7:40 PM Indianapolis, Illinois St (Greyhound Bus Station)
15h00
10:40 AM Greenville, Woodruff Rd ("Raceway" gas station), SC2 transfers
Greyhound+FlixBusFlixBus8:10 PM Indianapolis, Illinois St (Greyhound Bus Station)
15h50
12:00 PM Greenville, Woodruff Rd ("Raceway" gas station), SC1 transfer
FlixBusFlixBus · FlixBus11:25 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN
16h45
4:10 PM Greenville, Woodruff Rd ("Raceway" gas station), SC1 transfer
Greyhound+FlixBusFlixBus4:40 AM Indianapolis, Illinois St (Greyhound Bus Station)
16h50
9:30 PM Greenville, Woodruff Rd ("Raceway" gas station), SC1 transfer
Greyhound · 11:15 AM Indianapolis, Illinois St (Greyhound Bus Station)
16h00
3:15 AM Greenville, Woodruff Rd ("Raceway" gas station), SC1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

FAQs: Bus from Indianapolis, IN to Greenville, SC

Find answers to the most common questions about traveling from Indianapolis, IN to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

FAQs
The earliest bus from Indianapolis, IN to Greenville, SC leaves at 3:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Indianapolis, IN to Greenville, SC leaves at 11:30 PM.
Yes, you can take a between Indianapolis, IN and Greenville, SC.
No, the bus from Indianapolis, IN to Greenville, SC has no accessibility options.
No, there are no bathrooms on board the bus from Indianapolis, IN to Greenville, SC.
No, bikes are not allowed on board the bus from Indianapolis, IN to Greenville, SC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Indianapolis, IN to Greenville, SC.
No, luggage for the bus from Indianapolis, IN to Greenville, SC needs to be booked in addition.
No, there are no additional luggage options for the bus from Indianapolis, IN to Greenville, SC.
Unfortunately, pets are not allowed on the bus from Indianapolis, IN to Greenville, SC.
No, there are no USB plugs on board the bus from Indianapolis, IN to Greenville, SC.
No, there is no WiFi on board the bus from Indianapolis, IN to Greenville, SC.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Greenville, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and popular events. Common scams include overcharging by unofficial taxi or ride-share drivers and fake charity solicitations. It is advisable to use authorized transportation services, avoid displaying valuables openly, and stay aware of surroundings, particularly at night.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Indianapolis, IN to Greenville, SC

Most Indianapolis, IN to Greenville, SC buses use the Indianapolis, Illinois St (Greyhound Bus Station) to Greenville, Woodruff Rd ("Raceway" gas station) station pair. Use this guide to compare Indianapolis, IN and Greenville, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Indianapolis
Arrival bus stations in Greenville
Indianapolis, Illinois St (Greyhound Bus Station)
Indianapolis, E Washington St / N Delaware St (City/County Building)

More options for your journey from Indianapolis, IN to Greenville, SC

Here are some other resources that might have the information you need

Return journeys for buses from Greenville, SC to Indianapolis, IN
Flights from Indianapolis, IN to Greenville, SC
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Tickets and more information for coaches to Greenville, SC

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