- Recommended
Greenville County Museum of Art
A major art museum in downtown Greenville with American art, Southern works, and rotating exhibitions in a bright riverfront setting.
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Travel Information
Compare bus, train, and flight for Rochester, NY to Greenville, SC
Omio recommends booking the flight as it is the most popular option from Rochester, NY to Greenville, SC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €137 For those with little time, consider booking a flight, which has an average total journey time of 5h 49m. Average ticket prices depend on the travel mode: a bus costs an average of €137, while a flight costs an average of €459.
Distance: 628 miles (1011 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
€137 Average price Cheapest | €459 Average price | €353 Average price | €134 Average price (fuel + tolls) |
22h 54m Average total duration 22h 24m Onboard + 30m Additional time* | 5h 49m Average total duration Fastest 3h 49m Onboard + 2h 0m Additional time* | 23h 7m Average total duration 22h 37m Onboard + 30m Additional time* | 12h 11m Average total duration (door-to-door) |
 Most popular bus company |  Most popular airline |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Rochester, NY to Greenville, SC is a bus with an average price of €137.
This is compared to other travel options from Rochester, NY to Greenville, SC:
A bus is €216 less than a train for this route with tickets for a train from Rochester, NY to Greenville, SC costing on average €353.
A bus is €322 less than a flight for this route with tickets for a flight from Rochester, NY to Greenville, SC costing on average €459.
The fastest way to travel from Rochester, NY to Greenville, SC is by flight with an average journey time of 3h 49m.
Other travel options to Greenville, SC take longer:
Bus takes on average 22h 24m.
Train takes on average 22h 37m.
It's helpful to compare your options as there are 3 ways to travel between Rochester, NY and Greenville, SC including taking a bus, train, and flight.
We recommend using the bus as it is the most popular way to get from Rochester, NY to Greenville, SC among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around €137 compared to roughly €134 in fuel and tolls — a saving of about €-2.28. The journey takes 22h 24m versus 12h 11m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Rochester, NY to Greenville, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 06:55AM | Arrival Time 10:50AM | Duration 27h55 | Departure days Mon | Cheapest price €77 |
Operator FlixBus | Departure Time 06:55AM | Arrival Time 08:40AM | Duration 25h45 | Departure days Wed, Thu, Fri | Cheapest price €61 |
Operator FlixBus | Departure Time 09:05AM | Arrival Time 08:35AM | Duration 23h30 | Departure days Sun | Cheapest price €80 |
Operator FlixBus | Departure Time 12:05PM | Arrival Time 01:15PM | Duration 25h10 | Departure days Mon, Wed, Thu, Fri, Sun | Cheapest price €68 |
Operator FlixBus | Departure Time 06:55PM | Arrival Time 07:35PM | Duration 24h40 | Departure days Mon, Thu, Fri, Sun | Cheapest price €81 |
Operator Greyhound | Departure Time 11:35PM | Arrival Time 10:50AM | Duration 35h15 | Departure days Mon | Cheapest price €86 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 08:40AM | Duration 33h05 | Departure days Wed, Thu, Fri, Sun | Cheapest price €70 |
Live departures
Rochester, NY to Greenville, SC bus times
The table below shows live departures for Rochester, NY to Greenville, SC buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus+ | 6:55 PM Rochester, Pleasant St (Greyhound Stop), NY | 24h40 | 7:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 11:35 PM Rochester, Pleasant St (Greyhound Stop), NY | 33h05 | 8:40 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rochester, NY to Greenville, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Rochester, NY to Greenville, SC buses with Omio?
FlixBus operates all buses services from Rochester, NY to Greenville, SC.
Omio is an official ticket reseller for all your travel options from Rochester, NY to Greenville, SC.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Rochester, NY to Greenville, SC.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Rochester, NY to Greenville, SC.
Journey information
Overview: Bus from Rochester, NY to Greenville, SC
USAUSA
Buses from Rochester, NY to Greenville, SC run on average 4 times per day, taking around 22h 24m. Cheap bus tickets for this journey start at €79 if you book in advance.
The earliest bus runs at 07:10, the last at 22:00. The fastest bus covers the 628 miles (1011 km) distance in 20h 55m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 628 miles (1011 km) |
Average bus duration 22h 24m |
Cheapest ticket price €79 |
Buses per day 4 |
Fastest bus 20h 55m |
First bus 7:10 AM |
Last bus 10:00 PM |
Cheapest Month Aug |
Cheapest Day Fri |
High Season Jul - Sep |
Low Season Jan - Mar |
Best time to book 28 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus, Greyhound from Rochester, NY to Greenville, SCYou can travel by bus between Rochester, NY to Greenville, SC with FlixBus, Greyhound for as low as €79. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
20h 55m
Cheapest FlixBus Price
€79
FlixBus frequency
4 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
22h 40m
Cheapest Greyhound Price
€114
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Greenville, SC
Things to do in Greenville, SC
Discover the best of Greenville, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville, SC trip today.
Greenville Center for Creative Arts
A contemporary art center showing regional and international artists through rotating exhibitions in a modern downtown gallery space.
Metropolitan Arts Council Gallery
A local gallery and arts space featuring exhibitions, classes, and community-focused programming in Greenville's Village area.
- Must visit
Falls Park on the Reedy
A signature downtown park with waterfalls, gardens, river trails, and lawns. It is Greenville's most popular public space for walking and views.
- Must visit
Main Street
Greenville's central street lined with shops, public art, and historic buildings. It is ideal for strolling between downtown attractions.
- Recommended
Prisma Health Swamp Rabbit Trail
A swamp rabbit-themed riverside greenway popular for walking and cycling, linking downtown Greenville with parks and nearby districts.
FAQs: Bus from Rochester, NY to Greenville, SC
Find answers to the most common questions about traveling from Rochester, NY to Greenville, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Rochester, NY to Greenville, SC can start from as little as €79 when you book in advance. The average bus ticket price for Rochester, NY to Greenville, SC is €137 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Rochester, NY to Greenville, SC is 20h 55m to travel the 628 miles (1011 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Rochester, NY to Greenville, SC leaves at 7:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Rochester, NY to Greenville, SC leaves at 10:00 PM.
There are 4 buses a day from Rochester, NY to Greenville, SC which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Rochester, NY to Greenville, SC, you can count on FlixBus for the best way to get you to Greenville, SC. You can also check all possible bus companies who offer a service between Rochester, NY and Greenville, SC and compare the amenities they offer before buying a bus ticket.
Passengers board the bus most frequently from Rochester, Pleasant St (Greyhound Stop), NY, which is located around away from the city centre, and they get off the bus at Greenville, Woodruff Rd ("Raceway" gas station), SC, located 8 away from the city centre.
A trip to Greenville, SC from Rochester, NY is worth doing but not as a day trip with a journey time of 20h 55m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Rochester, NY to Greenville, SC is August.
It's helpful to compare your options as there are 3 ways to travel between Rochester, NY and Greenville, SC including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Rochester, NY to Greenville, SC:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Rochester, NY to Greenville, SC for bus company FlixBus.
Whether you can cancel your bus ticket from Rochester, NY to Greenville, SC depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Rochester, NY to Greenville, SC.
Yes, the following luggage options are included when booking a bus ticket from Rochester, NY to Greenville, SC:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Rochester, NY to Greenville, SC:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Rochester, NY to Greenville, SC. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Rochester, NY to Greenville, SC with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Rochester, NY to Greenville, SC with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Rochester, NY to Greenville, SC with the following bus company: FlixBus.
Since neither Rochester, NY nor Greenville, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Rochester, NY to Greenville, SC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Greenville, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and popular events. Common scams include overcharging by unofficial taxi or ride-share drivers and fake charity solicitations. It is advisable to use authorized transportation services, avoid displaying valuables openly, and stay aware of surroundings, particularly at night.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Rochester, NY to Greenville, SC
Most Rochester, NY to Greenville, SC buses use the Rochester, Pleasant St (Greyhound Stop) to Greenville, Woodruff Rd ("Raceway" gas station) station pair. Use this guide to compare Rochester, NY and Greenville, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Rochester
Arrival bus stations in Greenville
Which Rochester, NY station do buses to Greenville, SC leave from?
Buses from Rochester, NY to Greenville, SC leave from Rochester, Pleasant St (Greyhound Stop). The station is 0 miles (1 km) from Rochester, NY city centre at 120-124 Pleasant St, Rochester, NY 14604, USA.
Rochester, Pleasant St (Greyhound Stop)120-124 Pleasant St, Rochester, NY 14604, USA
City-centre transport
Getting to Rochester, Pleasant St (Greyhound Stop) from Rochester city centre
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Rochester, Pleasant St (Greyhound Stop) bus station facilities and services
Rochester, Pleasant St (Greyhound Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Rochester, Pleasant St (Greyhound Stop). ATMs are available at Rochester, Pleasant St (Greyhound Stop).
Tickets and information
Ticket office support is available at Rochester, Pleasant St (Greyhound Stop).
Parking, taxis and toilets
Available at Rochester, Pleasant St (Greyhound Stop): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Rochester, Pleasant St (Greyhound Stop): Accessible for disabled passengers.
Which Greenville, SC station do buses from Rochester, NY arrive at?
Buses from Rochester, NY to Greenville, SC arrive at Greenville, Woodruff Rd ("Raceway" gas station). Greenville, Woodruff Rd ("Raceway" gas station) is 4 miles (8 km) from Greenville, SC city centre.
Greenville, Woodruff Rd ("Raceway" gas station)Woodruff Rd, Greenville, SC, USA
City-centre transport
Getting to Greenville, Woodruff Rd ("Raceway" gas station) from Greenville city centre
Greenville, Woodruff Rd ("Raceway" gas station) is 8 km from Greenville city centre. Public transport options include:
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Greenville, Woodruff Rd ("Raceway" gas station) bus station facilities and services
Greenville, Woodruff Rd ("Raceway" gas station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Limited dining options available in adjacent areas.
Wi-Fi and ATMs
Wi-Fi is available at Greenville, Woodruff Rd ("Raceway" gas station). ATMs are available at Greenville, Woodruff Rd ("Raceway" gas station).
Tickets and information
Ticket office support is available at Greenville, Woodruff Rd ("Raceway" gas station).
Parking, taxis and toilets
Available at Greenville, Woodruff Rd ("Raceway" gas station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Greenville, Woodruff Rd ("Raceway" gas station): Basic access available for persons with disabilities.
Most popular bus connections from Rochester, NY
More options for your journey from Rochester, NY to Greenville, SC
Here are some other resources that might have the information you need
Most popular buses to and from Greenville, SC and Rochester, NY
Most popular bus connections to Greenville, SC
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