The cheapest and fastest buses from San Francisco, CA to Indianapolis, IN
Cheapest price
$926
Average price
$926
Fastest journey
2 d 19 h 35 m
Average duration
2 d 19 h 35 m
Buses per day
1
Distance
3130 km
The best way to find a cheap bus ticket from San Francisco, CA to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Francisco, CA to Indianapolis, IN will cost around $926 if you buy it on the day, but the cheapest tickets can be found for only $926.
It's difficult to get from San Francisco, CA to Indianapolis, IN without transferring at least 2 times.


San Francisco, CA to Indianapolis, IN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:30PM | Arrival Time 11:20PM | Duration 54h50 | Departure days Fri | Cheapest price $608 |
Operator Greyhound | Departure Time 10:40PM | Arrival Time 02:30PM | Duration 60h50 | Departure days Fri | Cheapest price $704 |
Live departures
San Francisco, CA to Indianapolis, IN bus times
The table below shows live departures for San Francisco, CA to Indianapolis, IN buses for today, Friday, January 23. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
undefined · undefined · undefined+ FlixBus | 9:30 PM San Francisco, Transit Center Bay 29 | 54h50 | 4:20 AM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 3 transfers | |
undefined · undefined · undefined · undefined | 9:30 PM San Francisco, Transit Center Bay 29 | 70h05 | 7:35 PM Indianapolis, 38th St / Franklin Rd (Shell), IN | 5 transfers | |
undefined · undefined · undefined · undefined | 9:30 PM San Francisco, Transit Center Bay 29 | 50h50 | 12:20 AM Indianapolis, Illinois St (Greyhound Bus Station) | 3 transfers | |
| Saturday, January 24 | |||||
undefined · undefined · undefined | 6:40 AM San Francisco, Transit Center Bay 29 | 60h50 | 7:30 PM Indianapolis, Illinois St (Greyhound Bus Station) | 2 transfers | |
![]() | 12:20 PM San Francisco, CA | 67h35 | 7:55 AM Indianapolis, IN | 2 transfers | |
Find all the dates and times for this journey
Compare prices and tickets San Francisco, CA to Indianapolis, IN by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from San Francisco, CA to Indianapolis, IN
Buses from San Francisco, CA to Indianapolis, IN run on average 12 times per day, taking around 57h 30m. Cheap bus tickets for this journey start at $935 (€748) if you book in advance.
The earliest bus runs at 03:15, the last at 23:55. The fastest bus covers the 1944 miles (3130 km) distance in 67h 35m.
Distance 1944 miles (3130 km) |
Average bus duration 57h 30m |
Cheapest ticket price $935 (€748) |
Buses per day 12 |
Fastest bus 67h 35m |
First bus 03:15 |
Last bus 23:55 |
Bus providers: Greyhound, FlixBus from San Francisco, CA to Indianapolis, INYou can travel by bus between San Francisco, CA to Indianapolis, IN with Greyhound, FlixBus for as low as $935 (€748). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from San Francisco, CA to Indianapolis, IN
Find answers to the most common questions about traveling from San Francisco, CA to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Indianapolis Motor Speedway, a historic racing circuit known for hosting the Indianapolis 500
- The Children's Museum of Indianapolis, the world's largest children's museum featuring interactive exhibits
- Indianapolis Zoo, a popular attraction with diverse animal exhibits and a botanical garden
- Indiana State Museum, showcasing the state's history, art, and science through various exhibits
- White River State Park, a sprawling urban park offering trails, gardens, and cultural attractions.
- Indianapolis Museum of Art at Newfields, a vast art museum with extensive collections and beautiful gardens
- Attend a race at the Indianapolis Motor Speedway, home of the iconic Indy 500
- Explore the interactive exhibits and educational programs at The Children's Museum of Indianapolis
- Visit the dolphin pavilion and animal habitats at the Indianapolis Zoo
- Enjoy a walk along the canal and cultural attractions at White River State Park.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from San Francisco, CA to Indianapolis, IN, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from San Francisco, CA to Indianapolis, IN
Most popular bus connections from San Francisco, CA
More options for your journey from San Francisco, CA to Indianapolis, IN
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