- Must visit
The Children's Museum of Indianapolis
World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.
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The cheapest and fastest buses from Orlando, FL to Indianapolis, IN
Showing times, prices and bookable tickets for Oct 24
Cheapest price on Oct 24
$96
Average ticket price on Oct 24
$97
Fastest journey on Oct 24
19 h 55 m
Average journey duration on Oct 24
21 h 46 m
Buses on Oct 24
8
Distance
1323 km
Cheap tickets
The best way to find a cheap bus ticket from Orlando, FL to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Orlando, FL to Indianapolis, IN will cost around $97 if you buy it on the day, but the cheapest tickets can be found for only $96.
Fast buses
It's difficult to get from Orlando, FL to Indianapolis, IN without transferring at least once.
FlixBus · FlixBus10:55 PM22h50Orlando, N John Young Pkwy (Greyhound Bus Station)9:45 PMIndianapolis, E Washington St / N Delaware St (City/County Building), IN$961One-way1 transfer- FlixBus · FlixBus9:30 AM22h30Orlando, N John Young Pkwy (Greyhound Bus Station)8:00 AMIndianapolis, E Washington St / N Delaware St (City/County Building), IN$961One-way1 transfer
- FlixBus+
8:50 PM19h55Orlando, N John Young Pkwy (Greyhound Bus Station)4:45 PMIndianapolis, Illinois St (Greyhound Bus Station)$961One-way1 transfer - FlixBus+2:45 PM21h25Orlando, N John Young Pkwy (Greyhound Bus Station)12:10 PMIndianapolis, Illinois St (Greyhound Bus Station)$971One-way1 transfer
- FlixBus+9:30 AM24h00Orlando, N John Young Pkwy (Greyhound Bus Station)9:30 AMIndianapolis, Illinois St (Greyhound Bus Station)$971One-way1 transfer
- FlixBus+8:50 PM19h55Orlando, N John Young Pkwy (Greyhound Bus Station)4:45 PMIndianapolis, Illinois St (Greyhound Bus Station)$961One-way1 transfer
- FlixBus+2:45 PM21h25Orlando, N John Young Pkwy (Greyhound Bus Station)12:10 PMIndianapolis, Illinois St (Greyhound Bus Station)$971One-way1 transfer
- FlixBus+2:00 PM22h10Orlando, The Florida Mall, FL12:10 PMIndianapolis, Illinois St (Greyhound Bus Station)$971One-way1 transfer
- FlixBus · FlixBus9:30 AM22h30Orlando, N John Young Pkwy (Greyhound Bus Station)8:00 AMIndianapolis, E Washington St / N Delaware St (City/County Building), IN$961One-way1 transfer
- FlixBus · FlixBus10:55 PM22h50Orlando, N John Young Pkwy (Greyhound Bus Station)9:45 PMIndianapolis, E Washington St / N Delaware St (City/County Building), IN$961One-way1 transfer
Journey information
Overview: Bus from Orlando, FL to Indianapolis, IN
USAUSA
Buses from Orlando, FL to Indianapolis, IN run on average 8 times per day, taking around 20h 38m. Cheap bus tickets for this journey start at $87 (€72) but you can travel from only $42 (€35) by flight.
The earliest bus runs at 00:15, the last at 23:55. The fastest bus covers the 822 miles (1323 km) distance in 19h 0m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $42 (€35)
Distance 822 miles (1323 km) |
Average bus duration 20h 38m |
Cheapest ticket price $87 (€72) |
Buses per day 8 |
Fastest bus 19h 0m |
First bus 12:15 AM |
Last bus 11:55 PM |
Cheapest Month Oct |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Tue |
Best time to book 28 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $42 (€35)
Frequently asked questions about your Orlando, FL to Indianapolis, IN trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Orlando, FL to Indianapolis, IN.
Cheap bus tickets from Orlando, FL to Indianapolis, IN can start from as little as $87 (€72) when you book in advance. The average bus ticket price for Orlando, FL to Indianapolis, IN is $129 (€108) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from Orlando, FL to Indianapolis, IN leaves at 12:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Orlando, FL to Indianapolis, IN leaves at 11:55 PM.
There are 8 buses a day from Orlando, FL to Indianapolis, IN which require at least one change with FlixBus, Greyhound. Schedules can vary on holidays or weekends with fewer buses.
Orlando, FL to Indianapolis, IN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:55AM | Arrival Time 09:40PM | Duration 20h45 | Departure days Fri, Sun | Cheapest price $135 |
Operator Greyhound | Departure Time 04:35AM | Arrival Time 12:10PM | Duration 31h35 | Departure days Thu | Cheapest price $121 |
Operator Greyhound | Departure Time 06:00AM | Arrival Time 04:55AM | Duration 22h55 | Departure days Everyday | Cheapest price $98 |
Operator Greyhound | Departure Time 09:30AM | Arrival Time 09:30AM | Duration 24h00 | Departure days Everyday | Cheapest price $97 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 08:00AM | Duration 22h30 | Departure days Everyday | Cheapest price $96 |
Operator Greyhound | Departure Time 12:30PM | Arrival Time 12:10PM | Duration 23h40 | Departure days Thu | Cheapest price $122 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 09:40PM | Duration 32h55 | Departure days Thu | Cheapest price $121 |
Operator Greyhound | Departure Time 12:45PM | Arrival Time 04:45PM | Duration 28h00 | Departure days Thu | Cheapest price $121 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 09:40PM | Duration 31h40 | Departure days Fri, Sun | Cheapest price $135 |
Operator Greyhound | Departure Time 02:00PM | Arrival Time 12:10PM | Duration 22h10 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $97 |
Operator Greyhound | Departure Time 02:45PM | Arrival Time 12:10PM | Duration 21h25 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $97 |
Operator Greyhound | Departure Time 08:50PM | Arrival Time 04:45PM | Duration 19h55 | Departure days Everyday | Cheapest price $96 |
Operator FlixBus | Departure Time 09:55PM | Arrival Time 09:40PM | Duration 23h45 | Departure days Thu, Fri, Sun | Cheapest price $131 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 09:45PM | Duration 22h50 | Departure days Mon, Sat | Cheapest price $96 |
Live departures
Orlando, FL to Indianapolis, IN bus times
The table below shows live departures for Orlando, FL to Indianapolis, IN buses for today, Friday, October 23. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus+ | 6:00 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 22h55 | 4:55 AM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
| FlixBus+ | 9:30 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 24h00 | 9:30 AM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
| FlixBus · FlixBus | 9:30 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 22h25 | 7:55 AM Indianapolis, IN | 1 transfer | |
| FlixBus+ | 2:00 PM Orlando, The Florida Mall, FL | 22h10 | 12:10 PM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
| FlixBus++FlixBus | 2:00 PM Orlando, The Florida Mall, FL | 31h40 | 9:40 PM Indianapolis, IN | 2 transfers | |
| FlixBus+ | 2:45 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 21h25 | 12:10 PM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
| FlixBus+ | 8:50 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 19h55 | 4:45 PM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
| FlixBus · FlixBus | 9:55 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 23h45 | 9:40 PM Indianapolis, IN | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Orlando, FL to Indianapolis, IN buses with Omio?
FlixBus as well as Greyhound offer buses services from Orlando, FL to Indianapolis, IN.
Omio is an official ticket reseller for all your travel options from Orlando, FL to Indianapolis, IN.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Orlando, FL to Indianapolis, IN.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Orlando, FL to Indianapolis, IN.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from Orlando, FL to Indianapolis, IN.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Orlando, FL to Indianapolis, IN.
Bus providers: Greyhound, FlixBus from Orlando, FL to Indianapolis, INYou can travel by bus between Orlando, FL to Indianapolis, IN with Greyhound, FlixBus for as low as $42 (€35). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
19h 0m
Cheapest FlixBus Price
$87 (€72)
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
19h 0m
Cheapest Greyhound Price
$88 (€73)
Greyhound frequency
6 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Companies, tickets, and onboard amenities between Orlando, FL and Indianapolis, IN
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from Orlando, FL to Indianapolis, IN, you can count on FlixBus, Greyhound for the best way to get you to Indianapolis, IN. You can also check all possible bus companies who offer a service between Orlando, FL and Indianapolis, IN and compare the amenities they offer before buying a bus ticket.
Yes, the following accessibility options are available when taking the bus from Orlando, FL to Indianapolis, IN:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Orlando, FL to Indianapolis, IN for bus company FlixBus, Greyhound.
Whether you can cancel your bus ticket from Orlando, FL to Indianapolis, IN depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Yes, there is food available to purchase on board the bus from Orlando, FL to Indianapolis, IN.
Yes, the following luggage options are included when booking a bus ticket from Orlando, FL to Indianapolis, IN:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Orlando, FL to Indianapolis, IN:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Orlando, FL to Indianapolis, IN. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Orlando, FL to Indianapolis, IN with the following bus company: FlixBus, Greyhound
Yes, there are USB plugs on board the bus from Orlando, FL to Indianapolis, IN with the following bus company: FlixBus, Greyhound.
Yes, there is Wifi on board the bus from Orlando, FL to Indianapolis, IN with the following bus company: FlixBus, Greyhound.
Complete guide to Indianapolis, IN
Things to do in Indianapolis, IN
Discover the best of Indianapolis, IN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis, IN trip today.
- Must visit
Indianapolis Museum of Art at Newfields
Leading art museum set on the Newfields campus, with major collections from Europe, Asia, Africa, and America plus temporary exhibitions.
- Recommended
Benjamin Harrison Presidential Site
Museum and restored home of the 23rd U.S. president. Guided visits reveal politics, domestic life, and architecture from the late 1800s.
- Must visit
Central Canal
Pedestrian-friendly downtown canal lined with museums, public art, and boats. Ideal for a scenic walk and one of the city's most popular areas.
- Must visit
Monument Circle
Historic city center surrounding the Soldiers and Sailors Monument. A signature urban space for architecture, events, and classic downtown views.
- Must visit
Indianapolis Cultural Trail
Popular cultural trail linking downtown districts with public art, bike lanes, and green streetscape design. Perfect for exploring the city on foot.
Pork Tenderloin Sandwich
Indiana pork tenderloin sandwich is a breaded, fried cutlet served on a bun, often comically oversized. It is a beloved statewide classic common in Indianapolis pubs and diners.
- Vegetarian
Sugar Cream Pie
Sugar cream pie is Indiana's state pie, made with cream, sugar, and nutmeg. Its simple farm-pantry origins make it a traditional Hoosier dessert tied closely to local identity.
- Gluten-free
St. Elmo-Style Shrimp Cocktail
Shrimp cocktail in Indianapolis style features chilled shrimp with very spicy tomato-horseradish sauce. St. Elmo made this fiery version a city dining icon.
Vida
Established fine-dining restaurant serving seasonal Midwestern cuisine with polished service. Known for refined plates and a warm, contemporary atmosphere.
St. Elmo Steak House
Historic downtown steakhouse famous for aged steaks and the city's iconic fiery shrimp cocktail. Classic, upscale atmosphere with longstanding local prestige.
Harry & Izzy's
Long-running Indianapolis institution known for classic steaks, seafood, and old-school service. A traditional downtown choice with historic local character.
United States Dollar ($)
Moderate for a U.S. city: hotels and dining are mid-range, while transit is limited so many visitors use rideshare or rental cars.
Average meal costs
- Budget
- $10-$18 for fast food or a casual meal.
- Mid-range
- $20-$40 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-$6 for coffee or a cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-$2 per drink at bars, and 10-15% for taxis. Small cafe tips are appreciated but optional.
Plan your visit to Indianapolis, IN
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Indianapolis, IN.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Indianapolis, travelers should be cautious of pickpocketing and vehicle break-ins, especially in busy areas like downtown and near major event venues. Common scams include overcharging by unofficial taxi or rideshare drivers and distraction tactics used to steal belongings. It's advised to use authorized transportation services, avoid poorly lit or unfamiliar areas at night, and keep valuables secure.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from Orlando, FL to Indianapolis, IN
Find answers to the most common questions about traveling from Orlando, FL to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.
It's helpful to compare your options as there are 3 ways to travel between Orlando, FL and Indianapolis, IN including taking a train, bus, and flight.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Popular bus stations from Orlando, FL to Indianapolis, IN
Most Orlando, FL to Indianapolis, IN buses use the Orlando, N John Young Pkwy (Greyhound Bus Station) to Indianapolis, Illinois St (Greyhound Bus Station) station pair. Use this guide to compare Orlando, FL and Indianapolis, IN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Orlando
Arrival bus stations in Indianapolis
Which Orlando, FL station do buses to Indianapolis, IN leave from?
Buses from Orlando, FL to Indianapolis, IN leave from Orlando, N John Young Pkwy (Greyhound Bus Station). The station is 1 miles (3 km) from Orlando, FL city centre at 555 John Young Pkwy, Orlando, FL 32805, USA.
Orlando, N John Young Pkwy (Greyhound Bus Station)555 John Young Pkwy, Orlando, FL 32805, USA
City-centre transport
Getting to Orlando, N John Young Pkwy (Greyhound Bus Station) from Orlando city centre
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Bus125 · 40m · $3 · every ~6 min
125 · 41m · $3 · every ~6 min
Orlando, N John Young Pkwy (Greyhound Bus Station) bus station facilities and services
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Parking, taxis and toilets
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.
Orlando, The Florida MallOrlando Florida Mall Ave,Florida Mall Ave 1632,32809
City-centre transport
Getting to Orlando, The Florida Mall from Orlando city centre
Bus42 · 26m · $3 · every ~5 min
Which Indianapolis, IN station do buses from Orlando, FL arrive at?
Buses from Orlando, FL to Indianapolis, IN arrive at Indianapolis, Illinois St (Greyhound Bus Station). Indianapolis, Illinois St (Greyhound Bus Station) is 0 miles (1 km) from Indianapolis, IN city centre.
Indianapolis, Illinois St (Greyhound Bus Station)350 S Illinois St, Indianapolis, IN 46225, USA
City-centre transport
Getting to Indianapolis, Illinois St (Greyhound Bus Station) from Indianapolis city centre
TRUE
Indianapolis, Illinois St (Greyhound Bus Station) bus station facilities and services
Indianapolis, Illinois St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Fast food outlets are available.
Wi-Fi and ATMs
Free Wi-Fi is available throughout the station. ATMs are aTM is located near the entrance.
Tickets and information
Ticket office support is available at Indianapolis, Illinois St (Greyhound Bus Station).
Parking, taxis and toilets
Available at Indianapolis, Illinois St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Indianapolis, Illinois St (Greyhound Bus Station): The station is wheelchair accessible.
Bus stations for Orlando, FL to Indianapolis, IN
Check bus stations information for Orlando, FL and Indianapolis, IN, including where buses depart and arrive on this route.
When departing from Orlando, FL , you have various bus station options to start your journey from including Orlando, N John Young Pkwy (Greyhound Bus Station), Orlando, The Florida Mall . When arriving in Indianapolis, IN , you can end your journey in bus stations like Indianapolis, Illinois St (Greyhound Bus Station) .Passengers board the bus most frequently from Orlando, N John Young Pkwy (Greyhound Bus Station), which is located around 1 miles (3 km) away from the city centre, and they get off the bus at Indianapolis, Illinois St (Greyhound Bus Station), located 1 away from the city centre.
Most popular bus connections from Orlando, FL
More options for your journey from Orlando, FL to Indianapolis, IN
Here are some other resources that might have the information you need
Most popular buses to and from Indianapolis, IN and Orlando, FL
Most popular bus connections to Indianapolis, IN
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