- Must visit
The Children's Museum of Indianapolis
World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.
Cheapest price on Oct 21
$102
Average ticket price on Oct 21
$138
Fastest journey on Oct 21
12 h 20 m
Average journey duration on Oct 21
13 h 13 m
Buses on Oct 21
3
Distance
791 km
The best way to find a cheap bus ticket from Harrisburg, PA to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Harrisburg, PA to Indianapolis, IN will cost around $138 if you buy it on the day, but the cheapest tickets can be found for only $102.
On Wed, Oct 21, we found 3 buses from Harrisburg, PA to Indianapolis, IN, including 3 direct services.
On Wed, Oct 21 the direct buses cover the 791 km distance in an average of 13 h 13 m but if you time it right, some buses will get you there in just 12 h 20 m .
On Wed, Oct 21 the slowest buses will take 14 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Buses from Harrisburg, PA to Indianapolis, IN run on average 8 times per day, taking around 13h 23m. Cheap bus tickets for this journey start at $70 (€58) if you book in advance.
There are 4 buses per day. The earliest bus runs at 00:15, the last at 21:10. The fastest bus covers the 491 miles (791 km) distance in 11h 45m.
Distance 491 miles (791 km) |
Average bus duration 13h 23m |
Cheapest ticket price $70 (€58) |
Buses per day 8 |
Direct buses 4 |
Fastest bus 11h 45m |
First bus 12:15 AM |
Last bus 9:10 PM |
Cheapest Month May |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 28 days |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:45AM | Arrival Time 02:45PM | Duration 14h00 | Departure days Wed, Fri | Cheapest price $97 |
Operator Greyhound | Departure Time 02:30AM | Arrival Time 06:10PM | Duration 15h40 | Departure days Fri, Sun | Cheapest price $92 |
Operator FlixBus | Departure Time 02:30AM | Arrival Time 04:00PM | Duration 13h30 | Departure days Sun | Cheapest price $83 |
Operator Flixbus USA | Departure Time 02:40PM | Arrival Time 03:00AM | Duration 12h20 | Departure days Wed, Fri, Sat, Sun | Cheapest price $80 |
Operator Greyhound USA | Departure Time 02:50PM | Arrival Time 04:10AM | Duration 13h20 | Departure days Wed, Fri, Sat, Sun | Cheapest price $77 |
Operator Greyhound USA | Departure Time 07:45PM | Arrival Time 09:45AM | Duration 14h00 | Departure days Wed, Sat | Cheapest price $156 |
Operator Greyhound | Departure Time 07:50PM | Arrival Time 09:20AM | Duration 13h30 | Departure days Fri, Sun | Cheapest price $77 |
Operator Greyhound | Departure Time 08:05PM | Arrival Time 01:15PM | Duration 17h10 | Departure days Fri, Sun | Cheapest price $81 |
Operator Greyhound | Departure Time 11:30PM | Arrival Time 06:10PM | Duration 18h40 | Departure days Fri, Sun | Cheapest price $92 |
Operator Greyhound | Departure Time 11:45PM | Arrival Time 01:30PM | Duration 13h45 | Departure days Mon, Tue, Thu | Cheapest price $67 |
Operator Greyhound | Departure Time 11:50PM | Arrival Time 01:20PM | Duration 13h30 | Departure days Tue | Cheapest price $112 |
The table below shows live departures for Harrisburg, PA to Indianapolis, IN buses for today, Tuesday, October 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:45 PM Harrisburg, PA | 13h45 | 1:30 PM Indianapolis, IN | 0 transfersDirect | |
![]() | 11:50 PM Harrisburg, PA | 13h30 | 1:20 PM Indianapolis, IN | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Indianapolis, IN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis, IN trip today.
World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.
Leading art museum set on the Newfields campus, with major collections from Europe, Asia, Africa, and America plus temporary exhibitions.
Museum and restored home of the 23rd U.S. president. Guided visits reveal politics, domestic life, and architecture from the late 1800s.
Pedestrian-friendly downtown canal lined with museums, public art, and boats. Ideal for a scenic walk and one of the city's most popular areas.
Historic city center surrounding the Soldiers and Sailors Monument. A signature urban space for architecture, events, and classic downtown views.
Popular cultural trail linking downtown districts with public art, bike lanes, and green streetscape design. Perfect for exploring the city on foot.
Indiana pork tenderloin sandwich is a breaded, fried cutlet served on a bun, often comically oversized. It is a beloved statewide classic common in Indianapolis pubs and diners.
Sugar cream pie is Indiana's state pie, made with cream, sugar, and nutmeg. Its simple farm-pantry origins make it a traditional Hoosier dessert tied closely to local identity.
Shrimp cocktail in Indianapolis style features chilled shrimp with very spicy tomato-horseradish sauce. St. Elmo made this fiery version a city dining icon.
Established fine-dining restaurant serving seasonal Midwestern cuisine with polished service. Known for refined plates and a warm, contemporary atmosphere.
Historic downtown steakhouse famous for aged steaks and the city's iconic fiery shrimp cocktail. Classic, upscale atmosphere with longstanding local prestige.
Long-running Indianapolis institution known for classic steaks, seafood, and old-school service. A traditional downtown choice with historic local character.
Moderate for a U.S. city: hotels and dining are mid-range, while transit is limited so many visitors use rideshare or rental cars.
Tip 18-20% at restaurants, $1-$2 per drink at bars, and 10-15% for taxis. Small cafe tips are appreciated but optional.
Find answers to the most common questions about traveling from Harrisburg, PA to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

Most Harrisburg, PA to Indianapolis, IN buses use the Harrisburg, Market St (Bus Station) to Indianapolis, Illinois St (Greyhound Bus Station) station pair. Use this guide to compare Harrisburg, PA and Indianapolis, IN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Harrisburg, Market St (Bus Station) is 1 km from Harrisburg city centre. Public transport options include:
Harrisburg, Market St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi inside the station. ATMs are available at Harrisburg, Market St (Bus Station).
Ticket office support is available at Harrisburg, Market St (Bus Station).
Available at Harrisburg, Market St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Harrisburg, Market St (Bus Station): Wheelchair accessible with ramps.
Indianapolis, Illinois St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Fast food outlets are available.
Free Wi-Fi is available throughout the station. ATMs are aTM is located near the entrance.
Ticket office support is available at Indianapolis, Illinois St (Greyhound Bus Station).
Available at Indianapolis, Illinois St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Indianapolis, Illinois St (Greyhound Bus Station): The station is wheelchair accessible.
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