The cheapest and fastest buses from Harrisburg, PA to Indianapolis, IN
Cheapest price
$125
Average price
$125
Fastest journey
14 h
Average duration
14 h
Buses per day
1
Distance
791 km
The best way to find a cheap bus ticket from Harrisburg, PA to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Harrisburg, PA to Indianapolis, IN will cost around $125 if you buy it on the day, but the cheapest tickets can be found for only $125.
Of the 1 buses that leave Harrisburg, PA for Indianapolis, IN on Sat, Mar 07, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Mar 07 the direct buses cover the 791 km distance in an average of 14 h but if you time it right, some buses will get you there in just 14 h .
On Sat, Mar 07 the slowest buses will take 14 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare train, bus, and flight for Harrisburg, PA to Indianapolis, IN
Omio recommends booking the bus as it is the most popular option from Harrisburg, PA to Indianapolis, IN among Omio's users. If you are prioritising price take the bus with prices starting from $78. For those with little time consider booking a flight which can get you there in 5h 56m. The ticket price range depends on the travel mode: a bus costs an average of $78, and a flight costs an average of $223.
Distance: 491 miles (791 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$105 Average price Cheapest | $247 Average price | $348 Average price |
12h 15m Average total duration 11h 45m Onboard + 30m Additional time* | 21h 0m Average total duration 20h 30m Onboard + 30m Additional time* | 8h 56m Average total duration Fastest 5h 56m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Harrisburg, PA to Indianapolis, IN bus times
The table below shows live departures for Harrisburg, PA to Indianapolis, IN buses for tomorrow, Friday, March 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:45 AM Harrisburg, PA | 14h00 | 2:45 PM Indianapolis, IN | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Harrisburg, PA to Indianapolis, IN by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 06
Mar 07
Mar 08
Mar 09
Mar 10
Mar 11
Mar 12
Why should you book Harrisburg, PA to Indianapolis, IN buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Harrisburg, PA to Indianapolis, IN.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Harrisburg, PA to Indianapolis, IN.
Journey information
Overview: Bus from Harrisburg, PA to Indianapolis, IN
Buses from Harrisburg, PA to Indianapolis, IN run on average 7 times per day, taking around 11h 45m. Cheap bus tickets for this journey start at $78 (€63) if you book in advance.
There are 2 buses per day. The earliest bus runs at 00:15, the last at 23:55. The fastest bus covers the 491 miles (791 km) distance in 14h 0m.
Distance 491 miles (791 km) |
Average bus duration 11h 45m |
Cheapest ticket price $78 (€63) |
Buses per day 7 |
Direct buses 2 |
Fastest bus 14h 0m |
First bus 00:15 |
Last bus 23:55 |
Cheapest month Aug |
Cheapest day Sun |
High season Jan - Mar |
Low season Oct - Dec |
Best day to book ahead 28 days |
Bus providers: Greyhound from Harrisburg, PA to Indianapolis, INYou can travel by bus between Harrisburg, PA to Indianapolis, IN with Greyhound for as low as $78 (€63). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Harrisburg, PA to Indianapolis, IN
Find answers to the most common questions about traveling from Harrisburg, PA to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Indianapolis Motor Speedway, a historic racing circuit known for hosting the Indianapolis 500
- The Children's Museum of Indianapolis, the world's largest children's museum featuring interactive exhibits
- Indianapolis Zoo, a popular attraction with diverse animal exhibits and a botanical garden
- Indiana State Museum, showcasing the state's history, art, and science through various exhibits
- White River State Park, a sprawling urban park offering trails, gardens, and cultural attractions.
- Indianapolis Museum of Art at Newfields, a vast art museum with extensive collections and beautiful gardens
- Attend a race at the Indianapolis Motor Speedway, home of the iconic Indy 500
- Explore the interactive exhibits and educational programs at The Children's Museum of Indianapolis
- Visit the dolphin pavilion and animal habitats at the Indianapolis Zoo
- Enjoy a walk along the canal and cultural attractions at White River State Park.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Harrisburg, PA to Indianapolis, IN
Most popular bus connections from Harrisburg, PA
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