San Diego, CA to Indianapolis, IN bus with Greyhound

Tue, Sep 01
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The cheapest and fastest buses from San Diego, CA to Indianapolis, IN

Showing times, prices and bookable tickets for Sep 01

Cheapest price on Sep 01

$341

Average ticket price on Sep 01

$353

Fastest journey on Sep 01

2 d 3 h 10 m

Average journey duration on Sep 01

2 d 3 h 25 m

Buses on Sep 01

2

Distance

2873 km

Cheap tickets

The best way to find a cheap bus ticket from San Diego, CA to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from San Diego, CA to Indianapolis, IN will cost around $353 if you buy it on the day, but the cheapest tickets can be found for only $341.

Fast buses

On Tue, Sep 01, we found 2 buses from San Diego, CA to Indianapolis, IN, including 2 direct services.

On Tue, Sep 01 the direct buses cover the 2873 km distance in an average of 2 d 3 h 25 m but if you time it right, some buses will get you there in just 2 d 3 h 10 m .

On Tue, Sep 01 the slowest buses will take 2 d 3 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • Greyhound
    7:40 PM51h40
    San Diego, CA
    11:20 PMIndianapolis, IN
    $3411One-way
    0 transfers
  • Greyhound
    8:10 PM51h10
    San Diego, CA
    11:20 PMIndianapolis, IN
    $3651One-way
    0 transfers

Travel Information

Compare train, bus, and flight for San Diego, CA to Indianapolis, IN

Omio recommends booking the flight as it is the most popular option from San Diego, CA to Indianapolis, IN among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $199 For those with little time, consider booking a flight, which has an average total journey time of 7h 46m. Average ticket prices depend on the travel mode: a bus costs an average of $199, while a train costs an average of $551.

Distance: 1785 miles (2873 km)

Compare bus with

Bus
Most popular
Flight
Train
Driving

$199

Average price

Cheapest

$245

Average price

$551

Average price

$438

Average price

(fuel + tolls)

45h 2m

Average total duration

44h 32m

Onboard

+

30m

Additional time*

7h 46m

Average total duration

Fastest

5h 46m

Onboard

+

2h 0m

Additional time*

67h 54m

Average total duration

67h 24m

Onboard

+

30m

Additional time*

29h 58m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from San Diego, CA to Indianapolis, IN is a bus with an average price of $199 (€161).

This is compared to other travel options from San Diego, CA to Indianapolis, IN:

A bus is $46 (€37) less than a flight for this route with tickets for a flight from San Diego, CA to Indianapolis, IN costing on average $245 (€198).

A bus is $352 (€285) less than a train for this route with tickets for a train from San Diego, CA to Indianapolis, IN costing on average $551 (€446).

The fastest way to travel from San Diego, CA to Indianapolis, IN is by flight with an average journey time of 5h 46m.

Other travel options to Indianapolis, IN take longer:

Bus takes on average 44h 32m.

Train takes on average 67h 24m.

It's helpful to compare your options as there are 3 ways to travel between San Diego, CA and Indianapolis, IN including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from San Diego, CA to Indianapolis, IN among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

San Diego, CA to Indianapolis, IN Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound Mexico
Departure Time
07:00AM
Arrival Time
02:30PM
Duration
55h30
Departure days
Thu
Cheapest price
$610
Operator
Greyhound
Departure Time
01:55PM
Arrival Time
06:30PM
Duration
52h35
Departure days
Wed
Cheapest price
$391
Operator
Greyhound
Departure Time
04:25PM
Arrival Time
03:20AM
Duration
58h55
Departure days
Fri
Cheapest price
$468
Operator
Greyhound
Departure Time
04:50PM
Arrival Time
01:25AM
Duration
56h35
Departure days
Fri
Cheapest price
$418
Operator
Greyhound
Departure Time
05:15PM
Arrival Time
07:30PM
Duration
50h15
Departure days
Sun
Cheapest price
$499
Operator
Greyhound Mexico
Departure Time
07:25PM
Arrival Time
07:25AM
Duration
60h00
Departure days
Thu
Cheapest price
$610
Operator
Greyhound
Departure Time
07:40PM
Arrival Time
11:20PM
Duration
51h40
Departure days
Tue, Sat, Sun
Cheapest price
$341
Operator
Greyhound
Departure Time
08:10PM
Arrival Time
03:20AM
Duration
55h10
Departure days
Mon, Tue
Cheapest price
$344

Live departures

San Diego, CA to Indianapolis, IN bus times

The table below shows live departures for San Diego, CA to Indianapolis, IN buses for today, Monday, August 31. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound8:10 PM San Diego, CA
55h10
3:20 AM Indianapolis, IN0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets San Diego, CA to Indianapolis, IN by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Tue
Sep 01
Wed
Sep 02
Thu
Sep 03
Fri
Sep 04
Sat
Sep 05
Sun
Sep 06
Mon
Sep 07

Why should you book San Diego, CA to Indianapolis, IN buses with Omio?

Greyhound as well as FlixBus offer buses services from San Diego, CA to Indianapolis, IN.
Omio is an official ticket reseller for all your travel options from San Diego, CA to Indianapolis, IN.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from San Diego, CA to Indianapolis, IN.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from San Diego, CA to Indianapolis, IN.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from San Diego, CA to Indianapolis, IN.
  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from San Diego, CA to Indianapolis, IN.

Journey information

Overview: Bus from San Diego, CA to Indianapolis, IN

USAUSA
USAUSA
Icon of bus

Buses from San Diego, CA to Indianapolis, IN run on average 16 times per day, taking around 44h 32m. Cheap bus tickets for this journey start at $131 (€106) if you book in advance.

The earliest bus runs at 03:15, the last at 23:55. The fastest bus covers the 1785 miles (2873 km) distance in 51h 10m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
1785 miles (2873 km)
Average bus duration
44h 32m
Cheapest ticket price
$131 (€106)
Buses per day
16
Fastest bus
51h 10m
First bus
3:15 AM
Last bus
11:55 PM
Cheapest Month
Dec
Cheapest Day
Sat
High Season
Apr - Jun
Low Season
Jan - Mar
Best time to book
1 day
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound, FlixBus from San Diego, CA to Indianapolis, INYou can travel by bus between San Diego, CA to Indianapolis, IN with Greyhound, FlixBus for as low as $131 (€106). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
58h 20m
Cheapest FlixBus Price
$138 (€111)
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
51h 10m
Cheapest Greyhound Price
$131 (€106)
Greyhound frequency
3 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to Indianapolis, IN

Things to do in Indianapolis, IN

Discover the best of Indianapolis, IN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis, IN trip today.

  • Must visit

The Children's Museum of Indianapolis

World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.

  • Must visit

Indianapolis Museum of Art at Newfields

Leading art museum set on the Newfields campus, with major collections from Europe, Asia, Africa, and America plus temporary exhibitions.

  • Recommended

Benjamin Harrison Presidential Site

Museum and restored home of the 23rd U.S. president. Guided visits reveal politics, domestic life, and architecture from the late 1800s.

United States Dollar ($)

Moderate for a U.S. city: hotels and dining are mid-range, while transit is limited so many visitors use rideshare or rental cars.

Average meal costs

Budget
$10-$18 for fast food or a casual meal.
Mid-range
$20-$40 per person for a restaurant meal.
Fine dining
$60+ per person for upscale dining.
Coffee
$3-$6 for coffee or a cappuccino.

Tipping culture

Tip 18-20% at restaurants, $1-$2 per drink at bars, and 10-15% for taxis. Small cafe tips are appreciated but optional.

FAQs: Bus from San Diego, CA to Indianapolis, IN

Find answers to the most common questions about traveling from San Diego, CA to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from San Diego, CA to Indianapolis, IN can start from as little as $131 (€106) when you book in advance. The average bus ticket price for San Diego, CA to Indianapolis, IN is $199 (€161) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Diego, CA to Indianapolis, IN is 51h 10m to travel the 1785 miles (2873 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from San Diego, CA to Indianapolis, IN leaves at 3:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Diego, CA to Indianapolis, IN leaves at 11:55 PM.
There are 16 buses a day from San Diego, CA to Indianapolis, IN which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Diego, CA to Indianapolis, IN, you can count on Greyhound, FlixBus for the best way to get you to Indianapolis, IN. You can also check all possible bus companies who offer a service between San Diego, CA and Indianapolis, IN and compare the amenities they offer before buying a bus ticket.
When departing from San Diego, CA , you have various bus station options to start your journey from including San Diego, Congress Street (Old Town Park), CA, San Diego, San Ysidro Transit Center, San Diego, West Harbor Drive (The Headquarters at Seaport District), CA, La Jolla, UCSD Health La Jolla Station, CA . When arriving in Indianapolis, IN , you can end your journey in bus stations like Indianapolis, Illinois St (Greyhound Bus Station), Indianapolis, E Washington St / N Delaware St (City/County Building), IN .Passengers board the bus most frequently from San Diego, Congress Street (Old Town Park), CA, which is located around 3 miles (5 km) away from the city centre, and they get off the bus at Indianapolis, Illinois St (Greyhound Bus Station), located 0 away from the city centre.
A trip to Indianapolis, IN from San Diego, CA is worth doing but not as a day trip with a journey time of 51h 10m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from San Diego, CA to Indianapolis, IN is December.
It's helpful to compare your options as there are 3 ways to travel between San Diego, CA and Indianapolis, IN including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from San Diego, CA to Indianapolis, IN:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from San Diego, CA to Indianapolis, IN for bus company Greyhound, FlixBus.
Some of the most interesting sights to explore in Indianapolis, IN are:
  • Indianapolis Motor Speedway, a historic racing circuit known for hosting the Indianapolis 500
  • The Children's Museum of Indianapolis, the world's largest children's museum featuring interactive exhibits
  • Indianapolis Zoo, a popular attraction with diverse animal exhibits and a botanical garden
  • Indiana State Museum, showcasing the state's history, art, and science through various exhibits
  • White River State Park, a sprawling urban park offering trails, gardens, and cultural attractions.
The best things to do in Indianapolis, IN include:
  • Indianapolis Museum of Art at Newfields, a vast art museum with extensive collections and beautiful gardens
  • Attend a race at the Indianapolis Motor Speedway, home of the iconic Indy 500
  • Explore the interactive exhibits and educational programs at The Children's Museum of Indianapolis
  • Visit the dolphin pavilion and animal habitats at the Indianapolis Zoo
  • Enjoy a walk along the canal and cultural attractions at White River State Park.
Whether you can cancel your bus ticket from San Diego, CA to Indianapolis, IN depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from San Diego, CA to Indianapolis, IN.
Yes, the following luggage options are included when booking a bus ticket from San Diego, CA to Indianapolis, IN:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from San Diego, CA to Indianapolis, IN:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from San Diego, CA to Indianapolis, IN. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from San Diego, CA to Indianapolis, IN with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from San Diego, CA to Indianapolis, IN with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from San Diego, CA to Indianapolis, IN with the following bus company: Greyhound, FlixBus.
Since neither San Diego, CA nor Indianapolis, IN are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from San Diego, CA to Indianapolis, IN among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Indianapolis, travelers should be cautious of pickpocketing and vehicle break-ins, especially in busy areas like downtown and near major event venues. Common scams include overcharging by unofficial taxi or rideshare drivers and distraction tactics used to steal belongings. It's advised to use authorized transportation services, avoid poorly lit or unfamiliar areas at night, and keep valuables secure.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from San Diego, CA to Indianapolis, IN

Most San Diego, CA to Indianapolis, IN buses use the San Diego, Congress Street (Old Town Park) to Indianapolis, Illinois St (Greyhound Bus Station) station pair, with some services arriving at Indianapolis, E Washington St / N Delaware St (City/County Building). Use this guide to compare San Diego, CA and Indianapolis, IN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in San Diego
Arrival bus stations in Indianapolis

Which San Diego, CA station do buses to Indianapolis, IN leave from?

Buses from San Diego, CA to Indianapolis, IN leave from San Diego, Congress Street (Old Town Park). The station is 3 miles (6 km) from San Diego, CA city centre at Congress St, San Diego, CA 92110, USA.
San Diego, Congress Street (Old Town Park)Congress St, San Diego, CA 92110, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to San Diego, Congress Street (Old Town Park) from San Diego city centre

San Diego, Congress Street (Old Town Park) is 5 km from San Diego city centre. Public transport options include:

BusFlixBus 2017 · 20m · $1
83 · 26m · $6
TramGreen, Blue, Event · 16m · every ~18 min
Blue · 21m · every ~9 min

San Diego, Congress Street (Old Town Park) bus station facilities and services

San Diego, Congress Street (Old Town Park) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Several dining options nearby.

Wi-Fi and ATMs

Wi-Fi is available at San Diego, Congress Street (Old Town Park). ATMs are available at San Diego, Congress Street (Old Town Park).

Tickets and information

Ticket office support is available at San Diego, Congress Street (Old Town Park).

Parking, taxis and toilets

Available at San Diego, Congress Street (Old Town Park): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at San Diego, Congress Street (Old Town Park): Wheelchair accessible routes available.

San Diego, San Ysidro Transit CenterSan Ysidro Station, San Diego, CA 92173, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to San Diego, San Ysidro Transit Center from San Diego city centre

San Diego, San Ysidro Transit Center is 22 km from San Diego city centre. Public transport options include:

BusFlixBus 2017 · 25m · $2
910 · 41m · $6
TramBlue · 41m · $17 · every ~14 min
Blue · 43m · $17 · every ~14 min

San Diego, San Ysidro Transit Center bus station facilities and services

San Diego, San Ysidro Transit Center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Several fast food eateries located nearby.

Wi-Fi and ATMs

Wi-Fi is available at San Diego, San Ysidro Transit Center. ATMs are available near the entrance.

Tickets and information

Ticket office support is available at San Diego, San Ysidro Transit Center.

Parking, taxis and toilets

Available at San Diego, San Ysidro Transit Center: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at San Diego, San Ysidro Transit Center: Wheelchair accessible with ramps.

San Diego, West Harbor Drive (The Headquarters at Seaport District)W Harbor Dr, San Diego, CA, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to San Diego, West Harbor Drive (The Headquarters at Seaport District) from San Diego city centre

San Diego, West Harbor Drive (The Headquarters at Seaport District) is 1 km from San Diego city centre. Public transport options include:

TRUE

San Diego, West Harbor Drive (The Headquarters at Seaport District) bus station facilities and services

San Diego, West Harbor Drive (The Headquarters at Seaport District) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Several dining options are in the area.

Wi-Fi and ATMs

Wi-Fi is available at San Diego, West Harbor Drive (The Headquarters at Seaport District). ATMs are available at San Diego, West Harbor Drive (The Headquarters at Seaport District).

Tickets and information

Ticket office support is available at San Diego, West Harbor Drive (The Headquarters at Seaport District).

Parking, taxis and toilets

Available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Accessible for persons with disabilities.

More options for your journey from San Diego, CA to Indianapolis, IN

Here are some other resources that might have the information you need

Most popular buses to and from Indianapolis, IN and San Diego, CA

HomeBusesBuses in USABus tickets to Indianapolis, INSan Diego, CA to Indianapolis, IN bus

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