San Diego, CA to Indianapolis, IN bus with Greyhound

Wed, Mar 04
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1,000+ travel companies
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The cheapest and fastest buses from San Diego, CA to Indianapolis, IN

Showing times and prices for Mar 04

Cheapest price

$485

Average price

$485

Fastest journey

2 d 3 h 5 m

Average duration

2 d 3 h 5 m

Buses per day

1

Distance

2873 km

Cheap tickets

The best way to find a cheap bus ticket from San Diego, CA to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from San Diego, CA to Indianapolis, IN will cost around $485 if you buy it on the day, but the cheapest tickets can be found for only $485.

Fast buses

Of the 1 buses that leave San Diego, CA for Indianapolis, IN on Wed, Mar 04, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Wed, Mar 04 the direct buses cover the 2873 km distance in an average of 2 d 3 h 5 m but if you time it right, some buses will get you there in just 2 d 3 h 5 m .

On Wed, Mar 04 the slowest buses will take 2 d 3 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

Greyhound
09:15PM51h05
San Diego, CA
12:20AMIndianapolis, IN
$4851One-way
0 transfers

Travel Information

Compare train, bus, and flight for San Diego, CA to Indianapolis, IN

Omio recommends booking the bus as it is the most popular option from San Diego, CA to Indianapolis, IN among Omio's users. If you are prioritising price take the flight with prices starting from $96. For those with little time consider booking a flight which can get you there in 5h 48m. The ticket price range depends on the travel mode: a flight costs an average of $96, and a train costs an average of $215.

Distance: 1785 miles (2873 km)

Compare bus with

Most popular
Bus
Flight
Train

$325

Average price

$247

Average price

Cheapest

$462

Average price

45h 7m

Average total duration

44h 37m

Onboard

+

30m

Additional time*

8h 48m

Average total duration

Fastest

5h 48m

Onboard

+

3h 0m

Additional time*

56h 49m

Average total duration

56h 19m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Direct Options

Live departures

San Diego, CA to Indianapolis, IN bus times

The table below shows live departures for San Diego, CA to Indianapolis, IN buses for today, Tuesday, March 3. You can also manually refresh the results below to see updated bus journeys.

Last updated at 7:03 PM
ProviderDepartsDurationArrivesTransfers
Tickets
greyhound7:50 PM San Diego, CA
71h40
7:30 PM Indianapolis, IN0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets San Diego, CA to Indianapolis, IN by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Wed
Mar 04
Thu
Mar 05
Fri
Mar 06
Sat
Mar 07
Sun
Mar 08
Mon
Mar 09
Tue
Mar 10

Why should you book San Diego, CA to Indianapolis, IN buses with Omio?

Greyhound as well as FlixBus offer buses services from San Diego, CA to Indianapolis, IN.
Omio is an official ticket reseller for all your travel options from San Diego, CA to Indianapolis, IN.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from San Diego, CA to Indianapolis, IN.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from San Diego, CA to Indianapolis, IN.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from San Diego, CA to Indianapolis, IN.
  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from San Diego, CA to Indianapolis, IN.

Journey information

Overview: Bus from San Diego, CA to Indianapolis, IN

USAUSA
USAUSA
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Buses from San Diego, CA to Indianapolis, IN run on average 16 times per day, taking around 44h 37m. Cheap bus tickets for this journey start at $152 (€123) but you can travel from only $96 (€77) by flight.

The earliest bus runs at 03:15, the last at 23:55. The fastest bus covers the 1785 miles (2873 km) distance in 50h 5m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $96 (€77)
Distance
1785 miles (2873 km)
Average bus duration
44h 37m
Cheapest ticket price
$152 (€123)
Buses per day
16
Fastest bus
50h 5m
First bus
03:15
Last bus
23:55
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $96 (€77)

Bus providers: Greyhound, FlixBus from San Diego, CA to Indianapolis, INYou can travel by bus between San Diego, CA to Indianapolis, IN with Greyhound, FlixBus for as low as $96 (€77). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
58h 20m
Cheapest Price
$138 (€111)
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
50h 5m
Cheapest Price
$152 (€123)
Greyhound frequency
17 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from San Diego, CA to Indianapolis, IN

Find answers to the most common questions about traveling from San Diego, CA to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from San Diego, CA to Indianapolis, IN can start from as little as $152 (€123) when you book in advance. The average bus ticket price for San Diego, CA to Indianapolis, IN is $325 (€263) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Diego, CA to Indianapolis, IN is 50h 5m to travel the 1785 miles (2873 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from San Diego, CA to Indianapolis, IN leaves at 3:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Diego, CA to Indianapolis, IN leaves at 11:55 PM.
There are 16 buses a day from San Diego, CA to Indianapolis, IN which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Diego, CA to Indianapolis, IN, you can count on Greyhound, FlixBus for the best way to get you to Indianapolis, IN. You can also check all possible bus companies who offer a service between San Diego, CA and Indianapolis, IN and compare the amenities they offer before buying a bus ticket.
A trip to Indianapolis, IN from San Diego, CA is worth doing but not as a day trip with a journey time of 50h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from San Diego, CA to Indianapolis, IN is December.
It's helpful to compare your options as there are 3 ways to travel between San Diego, CA and Indianapolis, IN including taking a train, bus, and flight.
Yes, there are bathrooms on board the bus from San Diego, CA to Indianapolis, IN for bus company Greyhound, FlixBus.
Yes, the following accessibility options are available when taking the bus from San Diego, CA to Indianapolis, IN:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Some of the most interesting sights to explore in Indianapolis, IN are:
  • Indianapolis Motor Speedway, a historic racing circuit known for hosting the Indianapolis 500
  • The Children's Museum of Indianapolis, the world's largest children's museum featuring interactive exhibits
  • Indianapolis Zoo, a popular attraction with diverse animal exhibits and a botanical garden
  • Indiana State Museum, showcasing the state's history, art, and science through various exhibits
  • White River State Park, a sprawling urban park offering trails, gardens, and cultural attractions.
The best things to do in Indianapolis, IN include:
  • Indianapolis Museum of Art at Newfields, a vast art museum with extensive collections and beautiful gardens
  • Attend a race at the Indianapolis Motor Speedway, home of the iconic Indy 500
  • Explore the interactive exhibits and educational programs at The Children's Museum of Indianapolis
  • Visit the dolphin pavilion and animal habitats at the Indianapolis Zoo
  • Enjoy a walk along the canal and cultural attractions at White River State Park.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from San Diego, CA to Indianapolis, IN depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from San Diego, CA to Indianapolis, IN.
Yes, the following luggage options are included when booking a bus ticket from San Diego, CA to Indianapolis, IN:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from San Diego, CA to Indianapolis, IN:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from San Diego, CA to Indianapolis, IN. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from San Diego, CA to Indianapolis, IN with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from San Diego, CA to Indianapolis, IN with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from San Diego, CA to Indianapolis, IN with the following bus company: Greyhound, FlixBus.

popular bus stations

Popular bus stations from San Diego, CA to Indianapolis, IN

San Diego
Indianapolis
The major bus station for departures in San Diego is San Diego, Congress Street (Old Town Park). Find all the information you need to know about services, amenities and connections at San Diego, Congress Street (Old Town Park) for your trip from San Diego to Indianapolis.
San Diego, Congress Street (Old Town Park)
information
San Diego, San Ysidro Transit Center
information
San Diego, West Harbor Drive (The Headquarters at Seaport District)
information

More options for your journey from San Diego, CA to Indianapolis, IN

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Most popular buses to and from Indianapolis, IN and San Diego, CA

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