San Diego, CA to Indianapolis, IN bus with Greyhound

Fri, Oct 16
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The cheapest and fastest buses from San Diego, CA to Indianapolis, IN

Showing times, prices and bookable tickets for Oct 16

Cheapest price on Oct 16

$165

Average ticket price on Oct 16

$183

Fastest journey on Oct 16

2 d 1 h 40 m

Average journey duration on Oct 16

2 d 3 h 27 m

Buses on Oct 16

18

Distance

2873 km

Cheap tickets

The best way to find a cheap bus ticket from San Diego, CA to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from San Diego, CA to Indianapolis, IN will cost around $183 if you buy it on the day, but the cheapest tickets can be found for only $165.

Fast buses

It's difficult to get from San Diego, CA to Indianapolis, IN without transferring at least 2 times.

  • FlixBusFlixBus+Greyhound · ·
    10:05 PM66h25
    San Diego, Congress Street (Old Town Park), CA
    7:30 PMIndianapolis, Illinois St (Greyhound Bus Station)
    $1651One-way
    4 transfers
  • FlixBusFlixBus+Greyhound · ·
    1:10 PM51h20
    San Diego, West Harbor Drive (The Headquarters at Seaport District), CA
    7:30 PMIndianapolis, Illinois St (Greyhound Bus Station)
    $1661One-way
    4 transfers
  • FlixBusFlixBus+Greyhound · ·
    10:05 PM70h10
    San Diego, Congress Street (Old Town Park), CA
    11:15 PMIndianapolis, IN
    $1661One-way
    4 transfers
  • FlixBusFlixBus+Greyhound · ·
    9:45 PM70h30
    San Diego, West Harbor Drive (The Headquarters at Seaport District), CA
    11:15 PMIndianapolis, IN
    $1661One-way
    4 transfers
  • FlixBusFlixBus+Greyhound · ·
    1:10 PM55h05
    San Diego, West Harbor Drive (The Headquarters at Seaport District), CA
    11:15 PMIndianapolis, IN
    $1671One-way
    4 transfers

Journey information

Overview: Bus from San Diego, CA to Indianapolis, IN

USAUSA
USAUSA
Icon of bus

Buses from San Diego, CA to Indianapolis, IN run on average 15 times per day, taking around 48h 31m. Cheap bus tickets for this journey start at $150 if you book in advance.

The earliest bus runs at 03:15, the last at 23:55. The fastest bus covers the 1785 miles (2873 km) distance in 42h 25m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
1785 miles (2873 km)
Average bus duration
48h 31m
Cheapest ticket price
$150
Buses per day
15
Fastest bus
42h 25m
First bus
3:15 AM
Last bus
11:55 PM
Cheapest Month
Dec
Cheapest Day
Sat
High Season
Apr - Jun
Low Season
Jan - Mar
Best time to book
1 day
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

San Diego, CA to Indianapolis, IN Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
09:15AM
Arrival Time
02:30PM
Duration
50h15
Departure days
Everyday
Cheapest price
$175
Operator
Greyhound
Departure Time
09:25AM
Arrival Time
07:30PM
Duration
55h05
Departure days
Everyday
Cheapest price
$140
Operator
Greyhound
Departure Time
09:50AM
Arrival Time
02:30PM
Duration
49h40
Departure days
Everyday
Cheapest price
$156
Operator
Greyhound
Departure Time
11:45AM
Arrival Time
11:15PM
Duration
56h30
Departure days
Thu
Cheapest price
$285
Operator
Greyhound
Departure Time
12:40PM
Arrival Time
12:05AM
Duration
56h25
Departure days
Everyday
Cheapest price
$167
Operator
Greyhound
Departure Time
01:10PM
Arrival Time
12:05AM
Duration
55h55
Departure days
Everyday
Cheapest price
$138
Operator
Greyhound
Departure Time
07:10PM
Arrival Time
04:55AM
Duration
54h45
Departure days
Everyday
Cheapest price
$175
Operator
Greyhound
Departure Time
07:45PM
Arrival Time
04:55AM
Duration
54h10
Departure days
Everyday
Cheapest price
$145
Operator
Greyhound
Departure Time
09:45PM
Arrival Time
11:15PM
Duration
70h30
Departure days
Mon, Tue, Wed, Fri, Sat, Sun
Cheapest price
$145
Operator
Greyhound
Departure Time
10:05PM
Arrival Time
11:15PM
Duration
70h10
Departure days
Mon, Tue, Wed, Fri, Sat, Sun
Cheapest price
$144
Operator
Greyhound
Departure Time
10:15PM
Arrival Time
07:30PM
Duration
66h15
Departure days
Thu
Cheapest price
$330
Operator
Greyhound
Departure Time
10:35PM
Arrival Time
07:30PM
Duration
65h55
Departure days
Thu
Cheapest price
$291

Live departures

San Diego, CA to Indianapolis, IN bus times

The table below shows live departures for San Diego, CA to Indianapolis, IN buses for today, Thursday, October 15. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
FlixBusFlixBus+Greyhound · · 12:40 PM San Diego, San Ysidro Transit Center
55h35
11:15 PM Indianapolis, IN4 transfers
FlixBusFlixBus+Greyhound · · 12:40 PM San Diego, San Ysidro Transit Center
51h50
7:30 PM Indianapolis, Illinois St (Greyhound Bus Station)4 transfers
FlixBusFlixBus+Greyhound · · 1:10 PM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA
55h05
11:15 PM Indianapolis, IN4 transfers
FlixBusFlixBus+Greyhound · · 1:10 PM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA
51h20
7:30 PM Indianapolis, Illinois St (Greyhound Bus Station)4 transfers
Greyhound · · · 7:10 PM San Diego, San Ysidro Transit Center
54h45
4:55 AM Indianapolis, Illinois St (Greyhound Bus Station)3 transfers
Greyhound · +FlixBusFlixBus · FlixBus7:10 PM San Diego, San Ysidro Transit Center
57h50
8:00 AM Indianapolis, IN3 transfers
Greyhound · · · 7:45 PM San Diego, Congress Street (Old Town Park), CA
54h10
4:55 AM Indianapolis, Illinois St (Greyhound Bus Station)3 transfers
Greyhound · +FlixBusFlixBus · FlixBus7:45 PM San Diego, Congress Street (Old Town Park), CA
57h15
8:00 AM Indianapolis, IN3 transfers
FlixBusFlixBus+Greyhound · · 10:15 PM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA
66h15
7:30 PM Indianapolis, Illinois St (Greyhound Bus Station)4 transfers
FlixBusFlixBus+Greyhound · · 10:15 PM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA
70h00
11:15 PM Indianapolis, IN4 transfers
FlixBusFlixBus+Greyhound · · 10:35 PM San Diego, Congress Street (Old Town Park), CA
65h55
7:30 PM Indianapolis, Illinois St (Greyhound Bus Station)4 transfers
FlixBusFlixBus+Greyhound · · 10:35 PM San Diego, Congress Street (Old Town Park), CA
69h40
11:15 PM Indianapolis, IN4 transfers
Friday, October 16
Greyhound · · · 9:15 AM San Diego, San Ysidro Transit Center
57h30
9:45 PM Indianapolis, IN4 transfers
Greyhound · · 9:15 AM San Diego, San Ysidro Transit Center
50h15
2:30 PM Indianapolis, Illinois St (Greyhound Bus Station)2 transfers
FlixBusFlixBus · FlixBus+Greyhound · 9:25 AM San Diego, Congress Street (Old Town Park), CA
58h50
11:15 PM Indianapolis, IN5 transfers
FlixBusFlixBus · FlixBus+Greyhound · 9:25 AM San Diego, Congress Street (Old Town Park), CA
55h05
7:30 PM Indianapolis, Illinois St (Greyhound Bus Station)5 transfers
Greyhound · · 9:50 AM San Diego, Congress Street (Old Town Park), CA
49h40
2:30 PM Indianapolis, Illinois St (Greyhound Bus Station)2 transfers
Greyhound · · · 9:50 AM San Diego, Congress Street (Old Town Park), CA
56h55
9:45 PM Indianapolis, IN4 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Why should you book San Diego, CA to Indianapolis, IN buses with Omio?

Greyhound operates all buses services from San Diego, CA to Indianapolis, IN.
Omio is an official ticket reseller for all your travel options from San Diego, CA to Indianapolis, IN.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from San Diego, CA to Indianapolis, IN.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from San Diego, CA to Indianapolis, IN.

Bus providers: Greyhound from San Diego, CA to Indianapolis, INYou can travel by bus between San Diego, CA to Indianapolis, IN with Greyhound for as low as $150. When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
42h 25m
Cheapest Greyhound Price
$150
Greyhound frequency
15 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to Indianapolis, IN

Things to do in Indianapolis, IN

Discover the best of Indianapolis, IN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis, IN trip today.

  • Must visit

The Children's Museum of Indianapolis

World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.

  • Must visit

Indianapolis Museum of Art at Newfields

Leading art museum set on the Newfields campus, with major collections from Europe, Asia, Africa, and America plus temporary exhibitions.

  • Recommended

Benjamin Harrison Presidential Site

Museum and restored home of the 23rd U.S. president. Guided visits reveal politics, domestic life, and architecture from the late 1800s.

United States Dollar ($)

Moderate for a U.S. city: hotels and dining are mid-range, while transit is limited so many visitors use rideshare or rental cars.

Average meal costs

Budget
$10-$18 for fast food or a casual meal.
Mid-range
$20-$40 per person for a restaurant meal.
Fine dining
$60+ per person for upscale dining.
Coffee
$3-$6 for coffee or a cappuccino.

Tipping culture

Tip 18-20% at restaurants, $1-$2 per drink at bars, and 10-15% for taxis. Small cafe tips are appreciated but optional.

FAQs: Bus from San Diego, CA to Indianapolis, IN

Find answers to the most common questions about traveling from San Diego, CA to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from San Diego, CA to Indianapolis, IN can start from as little as $150 when you book in advance. The average bus ticket price for San Diego, CA to Indianapolis, IN is $253 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Diego, CA to Indianapolis, IN is 42h 25m to travel the 1785 miles (2873 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from San Diego, CA to Indianapolis, IN leaves at 3:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Diego, CA to Indianapolis, IN leaves at 11:55 PM.
There are 15 buses a day from San Diego, CA to Indianapolis, IN which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Diego, CA to Indianapolis, IN, you can count on Greyhound for the best way to get you to Indianapolis, IN. You can also check all possible bus companies who offer a service between San Diego, CA and Indianapolis, IN and compare the amenities they offer before buying a bus ticket.
When departing from San Diego, CA , you have various bus station options to start your journey from including San Diego, Congress Street (Old Town Park), CA, San Diego, San Ysidro Transit Center, San Diego, West Harbor Drive (The Headquarters at Seaport District), CA, La Jolla, UCSD Health La Jolla Station, CA . When arriving in Indianapolis, IN , you can end your journey in bus stations like Indianapolis, Illinois St (Greyhound Bus Station) .Passengers board the bus most frequently from San Diego, Congress Street (Old Town Park), CA, which is located around 3 miles (5 km) away from the city centre, and they get off the bus at Indianapolis, Illinois St (Greyhound Bus Station), located 0 away from the city centre.
It's helpful to compare your options as there are 3 ways to travel between San Diego, CA and Indianapolis, IN including taking a train, bus, and flight.
Yes, there are bathrooms on board the bus from San Diego, CA to Indianapolis, IN for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from San Diego, CA to Indianapolis, IN:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Whether you can cancel your bus ticket from San Diego, CA to Indianapolis, IN depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from San Diego, CA to Indianapolis, IN.
Yes, the following luggage options are included when booking a bus ticket from San Diego, CA to Indianapolis, IN:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from San Diego, CA to Indianapolis, IN:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from San Diego, CA to Indianapolis, IN.
You can reserve your seat on the bus from San Diego, CA to Indianapolis, IN with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from San Diego, CA to Indianapolis, IN with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from San Diego, CA to Indianapolis, IN with the following bus company: Greyhound.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Indianapolis, travelers should be cautious of pickpocketing and vehicle break-ins, especially in busy areas like downtown and near major event venues. Common scams include overcharging by unofficial taxi or rideshare drivers and distraction tactics used to steal belongings. It's advised to use authorized transportation services, avoid poorly lit or unfamiliar areas at night, and keep valuables secure.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from San Diego, CA to Indianapolis, IN

Most San Diego, CA to Indianapolis, IN buses use the San Diego, Congress Street (Old Town Park) to Indianapolis, Illinois St (Greyhound Bus Station) station pair. Use this guide to compare San Diego, CA and Indianapolis, IN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in San Diego
Arrival bus stations in Indianapolis

Which San Diego, CA station do buses to Indianapolis, IN leave from?

Buses from San Diego, CA to Indianapolis, IN leave from San Diego, Congress Street (Old Town Park). The station is 3 miles (6 km) from San Diego, CA city centre at Congress St, San Diego, CA 92110, USA.
San Diego, Congress Street (Old Town Park)Congress St, San Diego, CA 92110, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to San Diego, Congress Street (Old Town Park) from San Diego city centre

San Diego, Congress Street (Old Town Park) is 5 km from San Diego city centre. Public transport options include:

BusFlixBus 2017 · 20m · $2
83 · 26m · $6
TramGreen, Blue, Event · 16m · every ~18 min
Blue · 21m · every ~9 min

San Diego, Congress Street (Old Town Park) bus station facilities and services

San Diego, Congress Street (Old Town Park) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Several dining options nearby.

Wi-Fi and ATMs

Wi-Fi is available at San Diego, Congress Street (Old Town Park). ATMs are available at San Diego, Congress Street (Old Town Park).

Tickets and information

Ticket office support is available at San Diego, Congress Street (Old Town Park).

Parking, taxis and toilets

Available at San Diego, Congress Street (Old Town Park): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at San Diego, Congress Street (Old Town Park): Wheelchair accessible routes available.

San Diego, San Ysidro Transit CenterSan Ysidro Station, San Diego, CA 92173, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to San Diego, San Ysidro Transit Center from San Diego city centre

San Diego, San Ysidro Transit Center is 22 km from San Diego city centre. Public transport options include:

BusFlixBus 2017 · 25m · $3
910 · 41m · $6
TramBlue · 41m · $17 · every ~14 min
Blue · 43m · $17 · every ~14 min

San Diego, San Ysidro Transit Center bus station facilities and services

San Diego, San Ysidro Transit Center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Several fast food eateries located nearby.

Wi-Fi and ATMs

Wi-Fi is available at San Diego, San Ysidro Transit Center. ATMs are available near the entrance.

Tickets and information

Ticket office support is available at San Diego, San Ysidro Transit Center.

Parking, taxis and toilets

Available at San Diego, San Ysidro Transit Center: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at San Diego, San Ysidro Transit Center: Wheelchair accessible with ramps.

San Diego, West Harbor Drive (The Headquarters at Seaport District)W Harbor Dr, San Diego, CA, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to San Diego, West Harbor Drive (The Headquarters at Seaport District) from San Diego city centre

San Diego, West Harbor Drive (The Headquarters at Seaport District) is 1 km from San Diego city centre. Public transport options include:

TRUE

San Diego, West Harbor Drive (The Headquarters at Seaport District) bus station facilities and services

San Diego, West Harbor Drive (The Headquarters at Seaport District) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Several dining options are in the area.

Wi-Fi and ATMs

Wi-Fi is available at San Diego, West Harbor Drive (The Headquarters at Seaport District). ATMs are available at San Diego, West Harbor Drive (The Headquarters at Seaport District).

Tickets and information

Ticket office support is available at San Diego, West Harbor Drive (The Headquarters at Seaport District).

Parking, taxis and toilets

Available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Accessible for persons with disabilities.

More options for your journey from San Diego, CA to Indianapolis, IN

Here are some other resources that might have the information you need

Most popular buses to and from Indianapolis, IN and San Diego, CA

HomeBusesBuses in USABus tickets to Indianapolis, INSan Diego, CA to Indianapolis, IN bus

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