- Must visit
The Children's Museum of Indianapolis
The world's largest children's museum, known for immersive science, culture, and history exhibits and strong family appeal.
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The cheapest and fastest trains from St. Louis, MO to Indianapolis, IN
Showing times and prices for Jul 02
Cheapest price
$154
Average price
$286
Fastest journey
12 h 20 m
Average duration
13 h 30 m
Trains per day
2
Distance
370 km
Cheap tickets
The best way to find a cheap train ticket from St. Louis, MO to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Indianapolis, IN will cost around $286 if you buy it on the day, but the cheapest tickets can be found for only $154.
Fast trains
It's difficult to get from St. Louis, MO to Indianapolis, IN without transferring at least once.
318 Lincoln Service Missouri River Runner · 8856 AMTRAK2:55 PM12h20St. Louis Station, St. Louis, MO4:15 AMIndianapolis Station, Indianapolis, IN$1541One-way1 transfer- 22 Texas Eagle · 50 Cardinal8:10 AM14h39St. Louis Station, St. Louis, MO11:49 PMIndianapolis Station, Indianapolis, IN$4171One-way1 transfer
- 318 Lincoln Service Missouri River Runner · 8856 AMTRAK2:55 PM12h20St. Louis Station, St. Louis, MO4:15 AMIndianapolis Station, Indianapolis, IN$1541One-way1 transfer
- 22 Texas Eagle · 50 Cardinal8:10 AM14h39St. Louis Station, St. Louis, MO11:49 PMIndianapolis Station, Indianapolis, IN$4171One-way1 transfer
Travel Information
Compare train, bus, and flight for St. Louis, MO to Indianapolis, IN
Omio recommends booking the bus as it is the most popular option from St. Louis, MO to Indianapolis, IN among Omio's users. If you are prioritising price take the bus with prices starting from $38. For those with little time consider booking a flight which can get you there in 2h 36m. The ticket price range depends on the travel mode: a bus costs an average of $38, and a flight costs an average of $135.
Distance: 229 miles (370 km)
Compare train with
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$144 Average price | $55 Average price Cheapest | $321 Average price | $48 Average price (fuel + tolls) |
8h 44m Average total duration 8h 14m Onboard + 30m Additional time* | 5h 2m Average total duration 4h 32m Onboard + 30m Additional time* | 5h 36m Average total duration Fastest 2h 36m Onboard + 3h 0m Additional time* | 3h 39m Average total duration (door-to-door) |
Most popular train company |  Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from St. Louis, MO to Indianapolis, IN is a bus with an average price of $55 (€46).
This is compared to other travel options from St. Louis, MO to Indianapolis, IN:
A bus is $89 (€73) less than a train for this route with tickets for a train from St. Louis, MO to Indianapolis, IN costing on average $144 (€119).
A bus is $265 (€219) less than a flight for this route with tickets for a flight from St. Louis, MO to Indianapolis, IN costing on average $321 (€264).
The fastest way to travel from St. Louis, MO to Indianapolis, IN is by flight with an average journey time of 2h 36m.
Other travel options to Indianapolis, IN take longer:
Bus takes on average 4h 32m.
Train takes on average 8h 14m.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Indianapolis, IN including taking a train, bus, and flight.
We recommend using the bus as it is the most popular way to get from St. Louis, MO to Indianapolis, IN among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.
Tickets start at around $144 (€119) compared to roughly $48 (€40) in fuel and tolls — a saving of about $-96.01 (€-79.11). The journey takes 8h 14m versus 3h 39m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
St. Louis, MO to Indianapolis, IN train times
The table below shows live departures for St. Louis, MO to Indianapolis, IN trains for today, Wednesday, July 1. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 318 Lincoln Service Missouri River Runner · 8856 AMTRAK | 2:55 PM St. Louis Station, St. Louis, MO | 12h20 | 4:15 AM Indianapolis Station, Indianapolis, IN | 1 transfer | |
| Thursday, July 2 | |||||
| 22 Texas Eagle · 50 Cardinal | 8:10 AM St. Louis Station, St. Louis, MO | 14h39 | 11:49 PM Indianapolis Station, Indianapolis, IN | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Indianapolis, IN by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from St. Louis, MO to Indianapolis, IN
USAUSA
Trains from St. Louis, MO to Indianapolis, IN run on average 3 times per day, taking around 8h 14m. Cheap train tickets for this journey start at $70 (€58) but you can travel from only $38 (€31) by bus.
The earliest train runs at 06:00, the last at 15:39. The fastest train covers the 229 miles (370 km) distance in 11h 0m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $38 (€31)
Distance 229 miles (370 km) |
Average train duration 8h 14m |
Cheapest ticket price $70 (€58) |
Trains per day 3 |
Fastest train 11h 0m |
First train 6:00 AM |
Last train 3:39 PM |
Cheapest Month Mar |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Apr - Jun |
Busiest Day Mon |
Least Busy Day Sat |
Best time to book 4 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $38 (€31)
Train companies: Amtrak from St. Louis, MO to Indianapolis, IN trainsAmtrak trains will get you between St. Louis, MO and Indianapolis, IN from $38 (€31). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
About
Amtrak is the main passenger train operator in the United States, providing medium- and long-distance intercity services across 46 states and three Canadian provinces. Operating over 300 trains daily and serving more than 500 destinations, Amtrak connects cities and regions nationwide through routes such as the high-speed Acela in the Northeast Corridor, the scenic Coast Starlight along the West Coast, and the Empire Builder linking Chicago to the Midwest and the Pacific Northwest. Other notable services include the Northeast Regional, Keystone Service, and the unique Auto Train, which allows passengers to bring their cars onboard. Amtrak offers a variety of classes to suit different budgets and travel needs, including Coach, Business, First Class, and Sleeper Class with options like Roomettes, Bedrooms, and Bedroom Suites for overnight journeys. Ticket types include Saver, Value, Flexible, Business, and Premium. Onboard amenities vary by service but may include comfortable seating, Wi-Fi, power outlets, dining options, and lounge access on select trains. Popular routes include Washington, D.C.–Boston, San Diego–San Luis Obispo, San Jose–Sacramento, and Chicago–Seattle.
Luggage & cancellation policy
Average Duration
11h 0m
Cheapest Price
$70 (€58)
Amtrak frequency
3 a day
Luggage included
2 personal items and 2 carry-on bags included free
Luggage storage
Overhead racks, under seats, and designated luggage areas at end of cars
Cancellation Policy
Cancellation policies depend on ticket type and timing
Refund
Full refund if train is canceled by Amtrak
Amenities on board the train
Wifi
Food sold onboard
Café car with snacks, beverages, and light meals. Long-distance trains have full-service dining cars
Seat reservation
Included in ticket price for Business and First Class. Optional fee for Coach Class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible restrooms, Red Cap assistance service, accessible platforms and stations
Pets
Small pets under 20 pounds allowed for $26 fee. Must be in carrier. Service animals travel free
Quiet zone
Complete guide to Indianapolis
Things to do in Indianapolis
Discover the best of Indianapolis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis trip today.
- Must visit
Newfields: Indianapolis Museum of Art
A major art museum with global collections, contemporary works, and landscaped grounds that make it one of the city's top cultural visits.
- Must visit
Indianapolis Motor Speedway Museum
A famous motorsports museum showcasing Indy 500 history, winning cars, and racing heritage tied closely to the city.
- Must visit
Monument Circle
The symbolic heart of downtown, centered on the Soldiers and Sailors Monument and surrounded by historic buildings and city energy.
- Must visit
Massachusetts Avenue
A lively cultural corridor known for independent shops, murals, nightlife, and a walkable urban atmosphere popular with locals.
- Must visit
The Cultural Trail
A well-designed urban trail connecting neighborhoods, public art, and major attractions, especially popular for walking and cycling.
Pork Tenderloin Sandwich
A Hoosier classic: a breaded and fried pork cutlet served on a bun, often comically larger than the bread. It is one of Central Indiana’s most iconic comfort foods.
- Vegetarian
Sugar Cream Pie
Indiana’s unofficial state pie, made with a simple custard-style filling of cream, sugar, and vanilla, often finished with cinnamon or nutmeg. It is a longtime regional dessert tradition.
- Gluten-free
Shrimp Cocktail
Indianapolis is famous for a fiery version of shrimp cocktail served with extra-spicy tomato-horseradish sauce. It became a signature steakhouse starter in the city.
St. Elmo Steak House
Historic downtown steakhouse best known for classic steaks, old-school service, and its famous spicy shrimp cocktail. A landmark Indianapolis dining experience.
Bluebeard
Well-regarded modern American restaurant in the Fletcher Place area, known for seasonal cooking, creative small plates, and a stylish setting.
Workingman's Friend
Classic, old-school tavern famous for thin griddled burgers and a no-frills neighborhood feel. It is one of the city’s most beloved casual food spots.
United States Dollar
Generally affordable by major U.S. city standards. Hotels vary by events; dining and transport are usually moderate.
Average meal costs
- Budget
- USD 10-15 for fast food or a casual lunch.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 75+ per person at upscale restaurants.
- Coffee
- USD 4-6 for a regular café coffee.
Tipping culture
Tip 18-20% at full-service restaurants; 15-20% for taxis and rideshares. USD 1-2 per drink at bars, USD 2-5 for hotel staff, and round up for casual service.
FAQs: Trains from St. Louis, MO to Indianapolis, IN
Find answers to the most common questions about traveling from St. Louis, MO to Indianapolis, IN by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.
Train ticket prices from St. Louis, MO to Indianapolis, IN can vary. The cheapest ticket starts at $70 (€58), while the average price is around $144 (€119).
The train from St. Louis, MO to Indianapolis, IN takes 11h 0m and runs 3 per day.
The distance by train from St. Louis, MO to Indianapolis, IN is 229 miles (370 km).
The first train from St. Louis, MO to Indianapolis, IN leaves at 6:00 AM.
The last train from St. Louis, MO to Indianapolis, IN leaves at 3:39 PM.
There is no high speed train available from St. Louis, MO to Indianapolis, IN.
There is no direct train service currently available from St. Louis, MO to Indianapolis, IN.
Unfortunately, there is no night train available from St. Louis, MO to Indianapolis, IN.
The train station in St. Louis, MO that goes to Indianapolis, IN is St. Louis Station, St. Louis, MO, which connects to Indianapolis Station, Indianapolis, IN.
The cheapest way to get from St. Louis, MO to Indianapolis, IN is by bus, with a cost of around $38 (€31).
The train journey from St. Louis, MO to Indianapolis, IN offers a mix of urban and rural scenery, passing through the lush landscapes of eastern Missouri and the farmlands of Illinois, providing a pleasant view but not typically considered a notably scenic route.
A day trip from St. Louis, MO to Indianapolis, IN is not feasible as the journey takes 11h 0m each way, covering a distance of 229 miles (370 km). Trains operate 3 times per day.
In Indianapolis, you can visit the Indianapolis Museum of Art at Newfields to enjoy its art collections and gardens, attend a race at the historic Indianapolis Motor Speedway, explore interactive exhibits at The Children's Museum of Indianapolis, and visit animal habitats at the Indianapolis Zoo. You can also enjoy a walk along the canal at White River State Park, which offers cultural attractions.
To explore Indianapolis, IN, and enjoy its key attractions such as the Indianapolis Motor Speedway, the Children's Museum, and the Indianapolis Zoo, a stay of 2 to 3 days is generally recommended.
Yes, you can take the train from St. Louis, MO to Indianapolis, IN.
Since neither St. Louis, MO nor Indianapolis, IN are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from St. Louis, MO to Indianapolis, IN among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Indianapolis, travelers should be cautious of pickpocketing and vehicle break-ins, especially in busy areas like downtown and near major event venues. Common scams include overcharging by unofficial taxi or rideshare drivers and distraction tactics used to steal belongings. It's advised to use authorized transportation services, avoid poorly lit or unfamiliar areas at night, and keep valuables secure.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from St. Louis, MO to Indianapolis, IN
Most St. Louis, MO to Indianapolis, IN trains use the St. Louis Station to Indianapolis Station station pair. Use this guide to compare St. Louis, MO and Indianapolis, IN train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Departure train stations in St. Louis
Arrival train stations in Indianapolis
Which St. Louis, MO station do trains to Indianapolis, IN leave from?
Trains from St. Louis, MO to Indianapolis, IN leave from St. Louis Station. The station is 0 miles (1 km) from St. Louis, MO city centre at 430 S 15th St, St. Louis, MO 63103, USA.
St. Louis Station430 S 15th St, St. Louis, MO 63103, USA+1 800-872-7245
City-centre transport
Getting to St. Louis Station from St. Louis city centre
TrainMlb, Mlr · 3m · $4 · every ~14 min
St. Louis Station train station facilities and services
St. Louis Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food and drink
Food options include: Landry's Seafood House, The Station Grille
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at St. Louis Station. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at St. Louis Station. Lost and found is available at the station.
Parking, taxis and toilets
Available at St. Louis Station: Parking, Taxis, WC.
Bike and car services
Available at St. Louis Station: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at St. Louis Station: Ramps, restrooms.
Shops, hotels and contact
Nearby hotels include St. Louis Union Station Hotel, Curio Collection by Hilton, Courtyard St. Louis Downtown West, Drury Inn St. Louis at Union Station.
Which Indianapolis, IN station do trains from St. Louis, MO arrive at?
Trains from St. Louis, MO to Indianapolis, IN arrive at Indianapolis Station. Indianapolis Station is 0 miles (1 km) from Indianapolis, IN city centre.
Indianapolis Station350 S Illinois St, Indianapolis, IN 46225, USA+1 800-872-7245
City-centre transport
Getting to Indianapolis Station from Indianapolis city centre
BusIndyGo routes available nearby
Indianapolis Station train station facilities and services
Indianapolis Station has practical services for this route, including Wifi, Parking, Dining, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Information Desk, and Luggage Carts.
Food and drink
Food options include: Harry & Izzy's, St. Elmo Steak House
Wi-Fi and ATMs
Free.
Tickets and information
Ticket office support is available at Indianapolis Station. Information desks are located in the main hall.
Parking, taxis and toilets
Available at Indianapolis Station: Parking, Taxis, WC.
Bike and car services
Available at Indianapolis Station: Bike Parking.
Accessibility
Accessibility facilities are available at Indianapolis Station: Ramps.
Shops, hotels and contact
Nearby hotels include Crowne Plaza Indianapolis-Dwtn-Union-Stn, Omni Severin Hotel, The Westin Indianapolis.
Most popular train connections from St. Louis, MO
More options for your journey from St. Louis, MO to Indianapolis, IN
Here are some other resources that might have the information you need
Most popular trains to and from Indianapolis, IN and St. Louis, MO
Most popular train connections to Indianapolis, IN
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