- Must visit
The Children's Museum of Indianapolis
World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.
The best way to find a cheap train ticket from St. Louis, MO to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Indianapolis, IN will cost around €127 if you buy it on the day, but the cheapest tickets can be found for only €107.
It's difficult to get from St. Louis, MO to Indianapolis, IN without transferring at least once.
318 Lincoln Service Missouri River Runner · 8856 Connecting Bus
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22 Texas Eagle · 50 Cardinal
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422 Texas Eagle · 50 Cardinal
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318 Lincoln Service Missouri River Runner · 8856 Connecting Bus
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22 Texas Eagle · 50 Cardinal
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422 Texas Eagle · 50 Cardinal
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Trains from St. Louis, MO to Indianapolis, IN run on average 1 times per day, taking around 10h 30m. Cheap train tickets for this journey start at €79 but you can travel from only €25 by bus.
The earliest train runs at 06:00, the last at 15:39. The fastest train covers the 229 miles (370 km) distance in 9h 47m.
Distance 229 miles (370 km) |
Average train duration 10h 30m |
Cheapest ticket price €79 |
Trains per day 1 |
Fastest train 9h 47m |
First train 6:00 AM |
Last train 3:39 PM |
Cheapest Month Jul |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Mon |
Least Busy Day Tue |
Best time to book 1 day |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from St. Louis, MO to Indianapolis, IN.
The table below shows live departures for St. Louis, MO to Indianapolis, IN trains for tomorrow, Saturday, November 14. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
22 Texas Eagle · 50 Cardinal | 8:10 AM St. Louis Station, St. Louis, MO | 14h39 | 11:49 PM Indianapolis Station, Indianapolis, IN | 1 transfer | |
422 Texas Eagle · 50 Cardinal | 8:10 AM St. Louis Station, St. Louis, MO | 14h39 | 11:49 PM Indianapolis Station, Indianapolis, IN | 1 transfer | |
318 Lincoln Service Missouri River Runner · 8856 Connecting Bus | 2:55 PM St. Louis Station, St. Louis, MO | 12h20 | 4:15 AM Indianapolis Station, Indianapolis, IN | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Indianapolis, IN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis, IN trip today.
World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.
Leading art museum set on the Newfields campus, with major collections from Europe, Asia, Africa, and America plus temporary exhibitions.
Museum and restored home of the 23rd U.S. president. Guided visits reveal politics, domestic life, and architecture from the late 1800s.
Pedestrian-friendly downtown canal lined with museums, public art, and boats. Ideal for a scenic walk and one of the city's most popular areas.
Historic city center surrounding the Soldiers and Sailors Monument. A signature urban space for architecture, events, and classic downtown views.
Popular cultural trail linking downtown districts with public art, bike lanes, and green streetscape design. Perfect for exploring the city on foot.
Indiana pork tenderloin sandwich is a breaded, fried cutlet served on a bun, often comically oversized. It is a beloved statewide classic common in Indianapolis pubs and diners.
Sugar cream pie is Indiana's state pie, made with cream, sugar, and nutmeg. Its simple farm-pantry origins make it a traditional Hoosier dessert tied closely to local identity.
Shrimp cocktail in Indianapolis style features chilled shrimp with very spicy tomato-horseradish sauce. St. Elmo made this fiery version a city dining icon.
Established fine-dining restaurant serving seasonal Midwestern cuisine with polished service. Known for refined plates and a warm, contemporary atmosphere.
Historic downtown steakhouse famous for aged steaks and the city's iconic fiery shrimp cocktail. Classic, upscale atmosphere with longstanding local prestige.
Long-running Indianapolis institution known for classic steaks, seafood, and old-school service. A traditional downtown choice with historic local character.
Moderate for a U.S. city: hotels and dining are mid-range, while transit is limited so many visitors use rideshare or rental cars.
Tip 18-20% at restaurants, $1-$2 per drink at bars, and 10-15% for taxis. Small cafe tips are appreciated but optional.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Indianapolis, IN.
Find answers to the most common questions about traveling from St. Louis, MO to Indianapolis, IN by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

Most St. Louis, MO to Indianapolis, IN trains use the St. Louis Station to Indianapolis Station station pair. Use this guide to compare St. Louis, MO and Indianapolis, IN train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
St. Louis Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: Landry's Seafood House, The Station Grille
Free. ATMs are available in the train station.
Ticket office support is available at St. Louis Station. Information desks are located in the main hall.
Luggage storage is available at St. Louis Station. Lost and found is available at the station.
Available at St. Louis Station: Parking, Taxis, WC.
Available at St. Louis Station: Bike Parking, Car Rental.
Accessibility facilities are available at St. Louis Station: Ramps, restrooms.
Nearby hotels include St. Louis Union Station Hotel, Curio Collection by Hilton, Courtyard St. Louis Downtown West, Drury Inn St. Louis at Union Station.
Indianapolis Station has practical services for this route, including Wifi, Parking, Dining, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Information Desk, and Luggage Carts.
Food options include: Harry & Izzy's, St. Elmo Steak House
Free.
Ticket office support is available at Indianapolis Station. Information desks are located in the main hall.
Available at Indianapolis Station: Parking, Taxis, WC.
Available at Indianapolis Station: Bike Parking.
Accessibility facilities are available at Indianapolis Station: Ramps.
Nearby hotels include Crowne Plaza Indianapolis-Dwtn-Union-Stn, Omni Severin Hotel, The Westin Indianapolis.
Check train stations information for St. Louis, MO and Indianapolis, IN, including where trains depart and arrive on this route.
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