- Must visit
The Children's Museum of Indianapolis
World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.
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The cheapest and fastest buses from Denver, CO to Indianapolis, IN
Showing times, prices and bookable tickets for Sep 20
Cheapest price on Sep 20
$133
Average ticket price on Sep 20
$139
Fastest journey on Sep 20
22 h 5 m
Average journey duration on Sep 20
1 d 4 h 43 m
Buses on Sep 20
5
Distance
1606 km
Cheap tickets
The best way to find a cheap bus ticket from Denver, CO to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Denver, CO to Indianapolis, IN will cost around $139 if you buy it on the day, but the cheapest tickets can be found for only $133.
Fast buses
It's difficult to get from Denver, CO to Indianapolis, IN without transferring at least once.
· 1:35 PM22h55Denver, Union Station2:30 PMIndianapolis, Illinois St (Greyhound Bus Station)$1331One-way1 transfer- +
FlixBus6:55 PM26h20Denver, Union Station11:15 PMIndianapolis, IN$1341One-way1 transfer - · +FlixBus · FlixBus8:10 PM37h40Denver, Union Station11:50 AMIndianapolis, IN$1361One-way3 transfers
- · +FlixBus7:25 PM34h35Denver, Union Station8:00 AMIndianapolis, IN$1441One-way2 transfers
- · 7:25 PM22h05Denver, Union Station7:30 PMIndianapolis, Illinois St (Greyhound Bus Station)$1461One-way1 transfer
- · 7:25 PM22h05Denver, Union Station7:30 PMIndianapolis, Illinois St (Greyhound Bus Station)$1461One-way1 transfer
- · 1:35 PM22h55Denver, Union Station2:30 PMIndianapolis, Illinois St (Greyhound Bus Station)$1331One-way1 transfer
- +FlixBus6:55 PM26h20Denver, Union Station11:15 PMIndianapolis, IN$1341One-way1 transfer
- · +FlixBus7:25 PM34h35Denver, Union Station8:00 AMIndianapolis, IN$1441One-way2 transfers
- · +FlixBus · FlixBus8:10 PM37h40Denver, Union Station11:50 AMIndianapolis, IN$1361One-way3 transfers
Travel Information
Compare train, bus, and flight for Denver, CO to Indianapolis, IN
Omio recommends booking the bus as it is the most popular option from Denver, CO to Indianapolis, IN among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $229 For those with little time, consider booking a flight, which has an average total journey time of 7h 41m. Average ticket prices depend on the travel mode: a bus costs an average of $229, while a flight costs an average of $671.
Distance: 997 miles (1606 km)
Compare bus with
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$229 Average price Cheapest | $671 Average price | $304 Average price | $227 Average price (fuel + tolls) |
26h 41m Average total duration 26h 11m Onboard + 30m Additional time* | 7h 41m Average total duration Fastest 5h 41m Onboard + 2h 0m Additional time* | 24h 4m Average total duration 23h 34m Onboard + 30m Additional time* | 16h 12m Average total duration (door-to-door) |
Most popular bus company |  Most popular airline |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Denver, CO to Indianapolis, IN is a bus with an average price of $229.
This is compared to other travel options from Denver, CO to Indianapolis, IN:
A bus is $75 less than a train for this route with tickets for a train from Denver, CO to Indianapolis, IN costing on average $304.
A bus is $441 less than a flight for this route with tickets for a flight from Denver, CO to Indianapolis, IN costing on average $671.
The fastest way to travel from Denver, CO to Indianapolis, IN is by flight with an average journey time of 5h 41m.
Other travel options to Indianapolis, IN take longer:
Train takes on average 23h 34m.
Bus takes on average 26h 11m.
It's helpful to compare your options as there are 3 ways to travel between Denver, CO and Indianapolis, IN including taking a train, bus, and flight.
We recommend using the bus as it is the most popular way to get from Denver, CO to Indianapolis, IN among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $229 compared to roughly $227 in fuel and tolls — a saving of about $-1.99. The journey takes 26h 11m versus 16h 12m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Denver, CO to Indianapolis, IN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:55AM | Arrival Time 03:20AM | Duration 26h25 | Departure days Sat | Cheapest price $224 |
Operator Greyhound | Departure Time 02:10AM | Arrival Time 04:55PM | Duration 38h45 | Departure days Sat | Cheapest price $250 |
Operator Greyhound | Departure Time 02:25AM | Arrival Time 12:20AM | Duration 21h55 | Departure days Sat | Cheapest price $180 |
Operator Greyhound | Departure Time 01:35PM | Arrival Time 02:30PM | Duration 22h55 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $130 |
Operator Greyhound | Departure Time 06:55PM | Arrival Time 11:15PM | Duration 26h20 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $130 |
Operator Greyhound | Departure Time 07:25PM | Arrival Time 08:00AM | Duration 34h35 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $129 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 11:50AM | Duration 37h40 | Departure days Wed, Thu, Sat, Sun | Cheapest price $133 |
Live departures
Denver, CO to Indianapolis, IN bus times
The table below shows live departures for Denver, CO to Indianapolis, IN buses for today, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · | 1:35 PM Denver, Union Station | 22h55 | 2:30 PM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
| +FlixBus | 6:55 PM Denver, Union Station | 26h20 | 11:15 PM Indianapolis, IN | 1 transfer | |
| · +FlixBus | 7:25 PM Denver, Union Station | 34h35 | 8:00 AM Indianapolis, IN | 2 transfers | |
| · | 7:25 PM Denver, Union Station | 22h05 | 7:30 PM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
| · +FlixBus · FlixBus | 8:10 PM Denver, Union Station | 37h40 | 11:50 AM Indianapolis, IN | 3 transfers |
Find all the dates and times for this journey
Compare prices and tickets Denver, CO to Indianapolis, IN by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Denver, CO to Indianapolis, IN buses with Omio?
Greyhound operates all buses services from Denver, CO to Indianapolis, IN.
Omio is an official ticket reseller for all your travel options from Denver, CO to Indianapolis, IN.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Denver, CO to Indianapolis, IN.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Denver, CO to Indianapolis, IN.
Journey information
Overview: Bus from Denver, CO to Indianapolis, IN
USAUSA
Buses from Denver, CO to Indianapolis, IN run on average 5 times per day, taking around 26h 11m. Cheap bus tickets for this journey start at $128 if you book in advance.
The earliest bus runs at 03:15, the last at 23:55. The fastest bus covers the 997 miles (1606 km) distance in 20h 55m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 997 miles (1606 km) |
Average bus duration 26h 11m |
Cheapest ticket price $128 |
Buses per day 5 |
Fastest bus 20h 55m |
First bus 3:15 AM |
Last bus 11:55 PM |
Cheapest Month Oct |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 1 day |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound, Infobus from Denver, CO to Indianapolis, INYou can travel by bus between Denver, CO to Indianapolis, IN with Greyhound, Infobus for as low as $128. When you search for schedules and tickets, Omio will show you the best journey
Infobus
About
Infobus is an international IT company that operates as an online service for finding and purchasing bus, train, and plane tickets, rather than being a bus company itself. Established in 2002, Infobus acts as an intermediary between passengers and various transport carriers, particularly helping smaller bus companies offer online booking services. They utilize their own "BusSystem" to manage routes and ticket sales globally. Infobus covers over 30 countries and 300 cities, offering a wide range of routes and daily departures. While amenities can vary by carrier, Infobus aims to provide affordable and convenient travel with features like online booking, 24/7 support, and prompt notifications.
Luggage & cancellation policy
Average Infobus Duration
21h 25m
Cheapest Infobus Price
$253
Infobus frequency
1 a day
Luggage included
One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
Additional luggage
10€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Transport for wheelchairs and mobility aids.
Bikes
Bikes are allowed; may require prior reservation and an additional fee.
Pets
Small pets allowed in carriers; larger pets may require a separate ticket.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
20h 55m
Cheapest Greyhound Price
$128
Greyhound frequency
5 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Indianapolis, IN
Things to do in Indianapolis, IN
Discover the best of Indianapolis, IN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis, IN trip today.
- Must visit
Indianapolis Museum of Art at Newfields
Leading art museum set on the Newfields campus, with major collections from Europe, Asia, Africa, and America plus temporary exhibitions.
- Recommended
Benjamin Harrison Presidential Site
Museum and restored home of the 23rd U.S. president. Guided visits reveal politics, domestic life, and architecture from the late 1800s.
- Must visit
Central Canal
Pedestrian-friendly downtown canal lined with museums, public art, and boats. Ideal for a scenic walk and one of the city's most popular areas.
- Must visit
Monument Circle
Historic city center surrounding the Soldiers and Sailors Monument. A signature urban space for architecture, events, and classic downtown views.
- Must visit
Indianapolis Cultural Trail
Popular cultural trail linking downtown districts with public art, bike lanes, and green streetscape design. Perfect for exploring the city on foot.
Pork Tenderloin Sandwich
Indiana pork tenderloin sandwich is a breaded, fried cutlet served on a bun, often comically oversized. It is a beloved statewide classic common in Indianapolis pubs and diners.
- Vegetarian
Sugar Cream Pie
Sugar cream pie is Indiana's state pie, made with cream, sugar, and nutmeg. Its simple farm-pantry origins make it a traditional Hoosier dessert tied closely to local identity.
- Gluten-free
St. Elmo-Style Shrimp Cocktail
Shrimp cocktail in Indianapolis style features chilled shrimp with very spicy tomato-horseradish sauce. St. Elmo made this fiery version a city dining icon.
Vida
Established fine-dining restaurant serving seasonal Midwestern cuisine with polished service. Known for refined plates and a warm, contemporary atmosphere.
St. Elmo Steak House
Historic downtown steakhouse famous for aged steaks and the city's iconic fiery shrimp cocktail. Classic, upscale atmosphere with longstanding local prestige.
Harry & Izzy's
Long-running Indianapolis institution known for classic steaks, seafood, and old-school service. A traditional downtown choice with historic local character.
United States Dollar ($)
Moderate for a U.S. city: hotels and dining are mid-range, while transit is limited so many visitors use rideshare or rental cars.
Average meal costs
- Budget
- $10-$18 for fast food or a casual meal.
- Mid-range
- $20-$40 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-$6 for coffee or a cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-$2 per drink at bars, and 10-15% for taxis. Small cafe tips are appreciated but optional.
FAQs: Bus from Denver, CO to Indianapolis, IN
Find answers to the most common questions about traveling from Denver, CO to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Denver, CO to Indianapolis, IN can start from as little as $128 when you book in advance. The average bus ticket price for Denver, CO to Indianapolis, IN is $229 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Denver, CO to Indianapolis, IN is 20h 55m to travel the 997 miles (1606 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Denver, CO to Indianapolis, IN leaves at 3:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Denver, CO to Indianapolis, IN leaves at 11:55 PM.
There are 5 buses a day from Denver, CO to Indianapolis, IN which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Denver, CO to Indianapolis, IN, you can count on Greyhound for the best way to get you to Indianapolis, IN. You can also check all possible bus companies who offer a service between Denver, CO and Indianapolis, IN and compare the amenities they offer before buying a bus ticket.
A trip to Indianapolis, IN from Denver, CO is worth doing but not as a day trip with a journey time of 20h 55m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Denver, CO to Indianapolis, IN is October.
It's helpful to compare your options as there are 3 ways to travel between Denver, CO and Indianapolis, IN including taking a train, bus, and flight.
Yes, there are bathrooms on board the bus from Denver, CO to Indianapolis, IN for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from Denver, CO to Indianapolis, IN:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Some of the most interesting sights to explore in Indianapolis, IN are:
- Indianapolis Motor Speedway, a historic racing circuit known for hosting the Indianapolis 500
- The Children's Museum of Indianapolis, the world's largest children's museum featuring interactive exhibits
- Indianapolis Zoo, a popular attraction with diverse animal exhibits and a botanical garden
- Indiana State Museum, showcasing the state's history, art, and science through various exhibits
- White River State Park, a sprawling urban park offering trails, gardens, and cultural attractions.
The best things to do in Indianapolis, IN include:
- Indianapolis Museum of Art at Newfields, a vast art museum with extensive collections and beautiful gardens
- Attend a race at the Indianapolis Motor Speedway, home of the iconic Indy 500
- Explore the interactive exhibits and educational programs at The Children's Museum of Indianapolis
- Visit the dolphin pavilion and animal habitats at the Indianapolis Zoo
- Enjoy a walk along the canal and cultural attractions at White River State Park.
Whether you can cancel your bus ticket from Denver, CO to Indianapolis, IN depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Denver, CO to Indianapolis, IN.
Yes, the following luggage options are included when booking a bus ticket from Denver, CO to Indianapolis, IN:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Denver, CO to Indianapolis, IN:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Denver, CO to Indianapolis, IN.
You can reserve your seat on the bus from Denver, CO to Indianapolis, IN with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Denver, CO to Indianapolis, IN with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Denver, CO to Indianapolis, IN with the following bus company: Greyhound.
Since neither Denver, CO nor Indianapolis, IN are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Denver, CO to Indianapolis, IN among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Indianapolis, travelers should be cautious of pickpocketing and vehicle break-ins, especially in busy areas like downtown and near major event venues. Common scams include overcharging by unofficial taxi or rideshare drivers and distraction tactics used to steal belongings. It's advised to use authorized transportation services, avoid poorly lit or unfamiliar areas at night, and keep valuables secure.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Denver, CO to Indianapolis, IN
Most Denver, CO to Indianapolis, IN buses use the Denver, Union Station to Indianapolis, Illinois St (Greyhound Bus Station) station pair. Use this guide to compare Denver, CO and Indianapolis, IN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Denver
Arrival bus stations in Indianapolis
Denver, Union Station
City-centre transport
Getting to Denver, Union Station from Denver city centre
Bus0, 10, 15, 19 · 10m · $4 · every ~27 min
15 · 13m · $4 · every ~12 min
DenverDenver Bus Station, Denver, CO 80205, USA
City-centre transport
Getting to Denver from Denver city centre
TRUE
Denver bus station facilities and services
Denver has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Denver. ATMs are available at Denver.
Tickets and information
Ticket office support is available at Denver.
Parking, taxis and toilets
Available at Denver: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Denver: The station is wheelchair accessible.
Which Indianapolis, IN station do buses from Denver, CO arrive at?
Buses from Denver, CO to Indianapolis, IN most often arrive at Indianapolis, Illinois St (Greyhound Bus Station). Some services arrive at {secondaryArrivalStation}, so check your ticket before travel to confirm your Indianapolis, IN arrival station.
Indianapolis, Illinois St (Greyhound Bus Station)350 S Illinois St, Indianapolis, IN 46225, USA
City-centre transport
Getting to Indianapolis, Illinois St (Greyhound Bus Station) from Indianapolis city centre
TRUE
Indianapolis, Illinois St (Greyhound Bus Station) bus station facilities and services
Indianapolis, Illinois St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Fast food outlets are available.
Wi-Fi and ATMs
Free Wi-Fi is available throughout the station. ATMs are aTM is located near the entrance.
Tickets and information
Ticket office support is available at Indianapolis, Illinois St (Greyhound Bus Station).
Parking, taxis and toilets
Available at Indianapolis, Illinois St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Indianapolis, Illinois St (Greyhound Bus Station): The station is wheelchair accessible.
Most popular bus connections from Denver, CO
More options for your journey from Denver, CO to Indianapolis, IN
Here are some other resources that might have the information you need
Most popular buses to and from Indianapolis, IN and Denver, CO
Most popular bus connections to Indianapolis, IN
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