- Must visit
The Children's Museum of Indianapolis
World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from San Antonio, TX to Indianapolis, IN
Showing times, prices and bookable tickets for Sep 09
Cheapest price on Sep 09
$119
Average ticket price on Sep 09
$119
Fastest journey on Sep 09
1 d 12 h 5 m
Average journey duration on Sep 09
1 d 12 h 5 m
Buses on Sep 09
1
Distance
1609 km
Cheap tickets
The best way to find a cheap bus ticket from San Antonio, TX to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to Indianapolis, IN will cost around $119 if you buy it on the day, but the cheapest tickets can be found for only $119.
Fast buses
On Wed, Sep 09, we found 1 buses from San Antonio, TX to Indianapolis, IN, including 1 direct services.
On Wed, Sep 09 the direct buses cover the 1609 km distance in an average of 1 d 12 h 5 m but if you time it right, some buses will get you there in just 1 d 12 h 5 m .
On Wed, Sep 09 the slowest buses will take 1 d 12 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
6:30 AM36h05San Antonio, TX6:35 PMIndianapolis, IN$1191One-way0 transfers
- 6:30 AM36h05San Antonio, TX6:35 PMIndianapolis, IN$1191One-way0 transfers
Travel Information
Compare bus, flight, and train for San Antonio, TX to Indianapolis, IN
Omio recommends booking the bus as it is the most popular option from San Antonio, TX to Indianapolis, IN among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $142 For those with little time, consider booking a flight, which has an average total journey time of 8h 19m. Average ticket prices depend on the travel mode: a bus costs an average of $142, while a train costs an average of $357.
Distance: 999 miles (1609 km)
Compare bus with
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$142 Average price Cheapest | $291 Average price | $357 Average price | $238 Average price (fuel + tolls) |
24h 47m Average total duration 24h 17m Onboard + 30m Additional time* | 8h 19m Average total duration Fastest 6h 19m Onboard + 2h 0m Additional time* | 31h 55m Average total duration 31h 25m Onboard + 30m Additional time* | 17h 10m Average total duration (door-to-door) |
Most popular bus company |  Most popular airline |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from San Antonio, TX to Indianapolis, IN is a bus with an average price of $142.
This is compared to other travel options from San Antonio, TX to Indianapolis, IN:
A bus is $149 less than a flight for this route with tickets for a flight from San Antonio, TX to Indianapolis, IN costing on average $291.
A bus is $215 less than a train for this route with tickets for a train from San Antonio, TX to Indianapolis, IN costing on average $357.
The fastest way to travel from San Antonio, TX to Indianapolis, IN is by flight with an average journey time of 6h 19m.
Other travel options to Indianapolis, IN take longer:
Bus takes on average 24h 17m.
Train takes on average 31h 25m.
It's helpful to compare your options as there are 3 ways to travel between San Antonio, TX and Indianapolis, IN including taking a bus, flight, and train.
We recommend using the bus as it is the most popular way to get from San Antonio, TX to Indianapolis, IN among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $142 compared to roughly $238 in fuel and tolls — a saving of about $96. The journey takes 24h 17m versus 17h 10m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
San Antonio, TX to Indianapolis, IN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:15AM | Arrival Time 01:25PM | Duration 36h10 | Departure days Wed | Cheapest price $235 |
Operator Greyhound | Departure Time 06:30AM | Arrival Time 06:35PM | Duration 36h05 | Departure days Wed | Cheapest price $119 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 12:25PM | Duration 47h40 | Departure days Thu, Sat | Cheapest price $296 |
Operator Greyhound | Departure Time 12:45PM | Arrival Time 06:30PM | Duration 29h45 | Departure days Mon, Fri | Cheapest price $133 |
Operator Greyhound | Departure Time 05:35PM | Arrival Time 01:25AM | Duration 31h50 | Departure days Sun | Cheapest price $246 |
Operator Greyhound | Departure Time 06:35PM | Arrival Time 09:35PM | Duration 27h00 | Departure days Thu, Sun | Cheapest price $212 |
Compare prices and tickets San Antonio, TX to Indianapolis, IN by bus, flight, or train
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Wed
Sep 09
Sep 09
Thu
Sep 10
Sep 10
Fri
Sep 11
Sep 11
Sat
Sep 12
Sep 12
Sun
Sep 13
Sep 13
Mon
Sep 14
Sep 14
Tue
Sep 15
Sep 15
Why should you book San Antonio, TX to Indianapolis, IN buses with Omio?
Greyhound operates all buses services from San Antonio, TX to Indianapolis, IN.
Omio is an official ticket reseller for all your travel options from San Antonio, TX to Indianapolis, IN.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, flight and train to ensure you get the best deal for traveling from San Antonio, TX to Indianapolis, IN.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, flight and train to find the ideal travel option from San Antonio, TX to Indianapolis, IN.
Journey information
Overview: Bus from San Antonio, TX to Indianapolis, IN
USAUSA
Buses from San Antonio, TX to Indianapolis, IN run on average 10 times per day, taking around 24h 17m. Cheap bus tickets for this journey start at $122 if you book in advance.
The earliest bus runs at 01:30, the last at 23:55. The fastest bus covers the 999 miles (1609 km) distance in 26h 25m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 999 miles (1609 km) |
Average bus duration 24h 17m |
Cheapest ticket price $122 |
Buses per day 10 |
Fastest bus 26h 25m |
First bus 1:30 AM |
Last bus 11:55 PM |
Cheapest Month May |
Cheapest Day Fri |
High Season Jul - Sep |
Low Season Apr - Jun |
Best time to book 70 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from San Antonio, TX to Indianapolis, INYou can travel by bus between San Antonio, TX to Indianapolis, IN with Greyhound for as low as $122. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
26h 25m
Cheapest Greyhound Price
$122
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Indianapolis, IN
Things to do in Indianapolis, IN
Discover the best of Indianapolis, IN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis, IN trip today.
- Must visit
Indianapolis Museum of Art at Newfields
Leading art museum set on the Newfields campus, with major collections from Europe, Asia, Africa, and America plus temporary exhibitions.
- Recommended
Benjamin Harrison Presidential Site
Museum and restored home of the 23rd U.S. president. Guided visits reveal politics, domestic life, and architecture from the late 1800s.
- Must visit
Central Canal
Pedestrian-friendly downtown canal lined with museums, public art, and boats. Ideal for a scenic walk and one of the city's most popular areas.
- Must visit
Monument Circle
Historic city center surrounding the Soldiers and Sailors Monument. A signature urban space for architecture, events, and classic downtown views.
- Must visit
Indianapolis Cultural Trail
Popular cultural trail linking downtown districts with public art, bike lanes, and green streetscape design. Perfect for exploring the city on foot.
Pork Tenderloin Sandwich
Indiana pork tenderloin sandwich is a breaded, fried cutlet served on a bun, often comically oversized. It is a beloved statewide classic common in Indianapolis pubs and diners.
- Vegetarian
Sugar Cream Pie
Sugar cream pie is Indiana's state pie, made with cream, sugar, and nutmeg. Its simple farm-pantry origins make it a traditional Hoosier dessert tied closely to local identity.
- Gluten-free
St. Elmo-Style Shrimp Cocktail
Shrimp cocktail in Indianapolis style features chilled shrimp with very spicy tomato-horseradish sauce. St. Elmo made this fiery version a city dining icon.
Vida
Established fine-dining restaurant serving seasonal Midwestern cuisine with polished service. Known for refined plates and a warm, contemporary atmosphere.
St. Elmo Steak House
Historic downtown steakhouse famous for aged steaks and the city's iconic fiery shrimp cocktail. Classic, upscale atmosphere with longstanding local prestige.
Harry & Izzy's
Long-running Indianapolis institution known for classic steaks, seafood, and old-school service. A traditional downtown choice with historic local character.
United States Dollar ($)
Moderate for a U.S. city: hotels and dining are mid-range, while transit is limited so many visitors use rideshare or rental cars.
Average meal costs
- Budget
- $10-$18 for fast food or a casual meal.
- Mid-range
- $20-$40 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-$6 for coffee or a cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-$2 per drink at bars, and 10-15% for taxis. Small cafe tips are appreciated but optional.
FAQs: Bus from San Antonio, TX to Indianapolis, IN
Find answers to the most common questions about traveling from San Antonio, TX to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.
Cheap bus tickets from San Antonio, TX to Indianapolis, IN can start from as little as $122 when you book in advance. The average bus ticket price for San Antonio, TX to Indianapolis, IN is $142 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Antonio, TX to Indianapolis, IN is 26h 25m to travel the 999 miles (1609 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from San Antonio, TX to Indianapolis, IN leaves at 1:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Antonio, TX to Indianapolis, IN leaves at 11:55 PM.
There are 10 buses a day from San Antonio, TX to Indianapolis, IN which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Antonio, TX to Indianapolis, IN, you can count on Greyhound for the best way to get you to Indianapolis, IN. You can also check all possible bus companies who offer a service between San Antonio, TX and Indianapolis, IN and compare the amenities they offer before buying a bus ticket.
When departing from San Antonio, TX , you have various bus station options to start your journey from including San Antonio, N St Mary's St (Greyhound), TX, San Antonio, Avenue A / Pearl Pkwy, TX . When arriving in Indianapolis, IN , you can end your journey in bus stations like Indianapolis, Illinois St (Greyhound Bus Station) .Passengers board the bus most frequently from San Antonio, N St Mary's St (Greyhound), TX, which is located around away from the city centre, and they get off the bus at Indianapolis, Illinois St (Greyhound Bus Station), located 0 away from the city centre.
A trip to Indianapolis, IN from San Antonio, TX is worth doing but not as a day trip with a journey time of 26h 25m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from San Antonio, TX to Indianapolis, IN is May.
It's helpful to compare your options as there are 3 ways to travel between San Antonio, TX and Indianapolis, IN including taking a bus, flight, and train.
Yes, the following accessibility options are available when taking the bus from San Antonio, TX to Indianapolis, IN:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from San Antonio, TX to Indianapolis, IN for bus company Greyhound.
Some of the most interesting sights to explore in Indianapolis, IN are:
- Indianapolis Motor Speedway, a historic racing circuit known for hosting the Indianapolis 500
- The Children's Museum of Indianapolis, the world's largest children's museum featuring interactive exhibits
- Indianapolis Zoo, a popular attraction with diverse animal exhibits and a botanical garden
- Indiana State Museum, showcasing the state's history, art, and science through various exhibits
- White River State Park, a sprawling urban park offering trails, gardens, and cultural attractions.
The best things to do in Indianapolis, IN include:
- Indianapolis Museum of Art at Newfields, a vast art museum with extensive collections and beautiful gardens
- Attend a race at the Indianapolis Motor Speedway, home of the iconic Indy 500
- Explore the interactive exhibits and educational programs at The Children's Museum of Indianapolis
- Visit the dolphin pavilion and animal habitats at the Indianapolis Zoo
- Enjoy a walk along the canal and cultural attractions at White River State Park.
Whether you can cancel your bus ticket from San Antonio, TX to Indianapolis, IN depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from San Antonio, TX to Indianapolis, IN.
Yes, the following luggage options are included when booking a bus ticket from San Antonio, TX to Indianapolis, IN:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from San Antonio, TX to Indianapolis, IN:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from San Antonio, TX to Indianapolis, IN.
You can reserve your seat on the bus from San Antonio, TX to Indianapolis, IN with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from San Antonio, TX to Indianapolis, IN with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from San Antonio, TX to Indianapolis, IN with the following bus company: Greyhound.
Since neither San Antonio, TX nor Indianapolis, IN are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from San Antonio, TX to Indianapolis, IN among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Indianapolis, travelers should be cautious of pickpocketing and vehicle break-ins, especially in busy areas like downtown and near major event venues. Common scams include overcharging by unofficial taxi or rideshare drivers and distraction tactics used to steal belongings. It's advised to use authorized transportation services, avoid poorly lit or unfamiliar areas at night, and keep valuables secure.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from San Antonio, TX to Indianapolis, IN
Most San Antonio, TX to Indianapolis, IN buses use the San Antonio, N St Mary's St (Greyhound) to Indianapolis, Illinois St (Greyhound Bus Station) station pair. Use this guide to compare San Antonio, TX and Indianapolis, IN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in San Antonio
Arrival bus stations in Indianapolis
Which San Antonio, TX station do buses to Indianapolis, IN leave from?
Buses from San Antonio, TX to Indianapolis, IN leave from San Antonio, N St Mary's St (Greyhound). The station is 0 miles (1 km) from San Antonio, TX city centre at 500 N St Mary's St, San Antonio, TX 78205, USA.
San Antonio, N St Mary's St (Greyhound)500 N St Mary's St, San Antonio, TX 78205, USA
City-centre transport
Getting to San Antonio, N St Mary's St (Greyhound) from San Antonio city centre
TRUE
San Antonio, N St Mary's St (Greyhound) bus station facilities and services
San Antonio, N St Mary's St (Greyhound) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at San Antonio, N St Mary's St (Greyhound). ATMs are available at San Antonio, N St Mary's St (Greyhound).
Tickets and information
Ticket office support is available at San Antonio, N St Mary's St (Greyhound).
Parking, taxis and toilets
Available at San Antonio, N St Mary's St (Greyhound): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Antonio, N St Mary's St (Greyhound): Limited accessibility features.
San Antonio, Avenue A / Pearl PkwyAvenue A & Pearl Pkwy, San Antonio, TX 78215, USA
City-centre transport
Getting to San Antonio, Avenue A / Pearl Pkwy from San Antonio city centre
San Antonio, Avenue A / Pearl Pkwy is 2 km from San Antonio city centre. Public transport options include:
BusFlixBus 2230 · 11m · $1
10, 14, 214, 9 · 12m · $2 · every ~17 min
San Antonio, Avenue A / Pearl Pkwy bus station facilities and services
San Antonio, Avenue A / Pearl Pkwy has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Nearby Pearl Brewery offers dining options.
Wi-Fi and ATMs
Wi-Fi is available at San Antonio, Avenue A / Pearl Pkwy. ATMs are available at San Antonio, Avenue A / Pearl Pkwy.
Tickets and information
Ticket office support is available at San Antonio, Avenue A / Pearl Pkwy.
Parking, taxis and toilets
Available at San Antonio, Avenue A / Pearl Pkwy: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Antonio, Avenue A / Pearl Pkwy: Accessible to wheelchair users.
Which Indianapolis, IN station do buses from San Antonio, TX arrive at?
Buses from San Antonio, TX to Indianapolis, IN most often arrive at Indianapolis, Illinois St (Greyhound Bus Station). Some services arrive at {secondaryArrivalStation}, so check your ticket before travel to confirm your Indianapolis, IN arrival station.
Indianapolis, Illinois St (Greyhound Bus Station)350 S Illinois St, Indianapolis, IN 46225, USA
City-centre transport
Getting to Indianapolis, Illinois St (Greyhound Bus Station) from Indianapolis city centre
TRUE
Indianapolis, Illinois St (Greyhound Bus Station) bus station facilities and services
Indianapolis, Illinois St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Fast food outlets are available.
Wi-Fi and ATMs
Free Wi-Fi is available throughout the station. ATMs are aTM is located near the entrance.
Tickets and information
Ticket office support is available at Indianapolis, Illinois St (Greyhound Bus Station).
Parking, taxis and toilets
Available at Indianapolis, Illinois St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Indianapolis, Illinois St (Greyhound Bus Station): The station is wheelchair accessible.
Most popular bus connections from San Antonio, TX
More options for your journey from San Antonio, TX to Indianapolis, IN
Here are some other resources that might have the information you need
Most popular buses to and from Indianapolis, IN and San Antonio, TX
Most popular bus connections to Indianapolis, IN
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
