- Must visit
The Children's Museum of Indianapolis
World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.
Cheapest price on Oct 24
$134
Average ticket price on Oct 24
$140
Fastest journey on Oct 24
1 d 2 h 25 m
Average journey duration on Oct 24
1 d 3 h 45 m
Buses on Oct 24
12
Distance
1609 km
The best way to find a cheap bus ticket from San Antonio, TX to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to Indianapolis, IN will cost around $140 if you buy it on the day, but the cheapest tickets can be found for only $134.
It's difficult to get from San Antonio, TX to Indianapolis, IN without transferring at least 2 times.
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· Buses from San Antonio, TX to Indianapolis, IN run on average 10 times per day, taking around 26h 48m. Cheap bus tickets for this journey start at $114 (€96) if you book in advance.
The earliest bus runs at 01:30, the last at 23:55. The fastest bus covers the 999 miles (1609 km) distance in 23h 10m.
Distance 999 miles (1609 km) |
Average bus duration 26h 48m |
Cheapest ticket price $114 (€96) |
Buses per day 10 |
Fastest bus 23h 10m |
First bus 1:30 AM |
Last bus 11:55 PM |
Cheapest Month May |
Cheapest Day Fri |
High Season Jul - Sep |
Low Season Apr - Jun |
Best time to book 70 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from San Antonio, TX to Indianapolis, IN.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:30AM | Arrival Time 08:00AM | Duration 29h30 | Departure days Everyday | Cheapest price $133 |
Operator Greyhound | Departure Time 04:20AM | Arrival Time 12:10PM | Duration 30h50 | Departure days Tue, Wed | Cheapest price $133 |
Operator FlixBus | Departure Time 04:20AM | Arrival Time 09:30AM | Duration 28h10 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $126 |
Operator Greyhound | Departure Time 07:30AM | Arrival Time 02:30PM | Duration 30h00 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $133 |
Operator FlixBus | Departure Time 07:45AM | Arrival Time 08:00AM | Duration 47h15 | Departure days Mon, Wed | Cheapest price $131 |
Operator Greyhound | Departure Time 07:45AM | Arrival Time 02:30PM | Duration 29h45 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $132 |
Operator Greyhound | Departure Time 09:45AM | Arrival Time 09:30AM | Duration 46h45 | Departure days Sat, Sun | Cheapest price $127 |
Operator FlixBus | Departure Time 09:45AM | Arrival Time 08:00AM | Duration 45h15 | Departure days Sat, Sun | Cheapest price $126 |
Operator Greyhound | Departure Time 11:59AM | Arrival Time 04:45PM | Duration 27h46 | Departure days Everyday | Cheapest price $133 |
Operator Greyhound | Departure Time 09:00PM | Arrival Time 04:55AM | Duration 30h55 | Departure days Wed, Thu | Cheapest price $132 |
Operator Greyhound | Departure Time 09:55PM | Arrival Time 04:55AM | Duration 30h00 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $132 |
The table below shows live departures for San Antonio, TX to Indianapolis, IN buses for today, Friday, October 23. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
+ FlixBus+![]() | 4:20 AM San Antonio, N St Mary's St (Greyhound), TX | 28h10 | 9:30 AM Indianapolis, Illinois St (Greyhound Bus Station) | 2 transfers | |
+ FlixBus · FlixBus | 4:20 AM San Antonio, N St Mary's St (Greyhound), TX | 26h40 | 8:00 AM Indianapolis, IN | 2 transfers | |
FlixBus · FlixBus+ · | 7:30 AM San Antonio, N St Mary's St (Greyhound), TX | 30h00 | 2:30 PM Indianapolis, Illinois St (Greyhound Bus Station) | 3 transfers | |
FlixBus · FlixBus+ · | 7:45 AM San Antonio, Avenue A / Pearl Pkwy, TX | 29h45 | 2:30 PM Indianapolis, Illinois St (Greyhound Bus Station) | 3 transfers | |
FlixBus · FlixBus+ + FlixBus | 7:45 AM San Antonio, Avenue A / Pearl Pkwy, TX | 38h30 | 11:15 PM Indianapolis, IN | 4 transfers | |
· · + FlixBus | 11:59 AM San Antonio, N St Mary's St (Greyhound), TX | 32h46 | 9:45 PM Indianapolis, IN | 3 transfers | |
· · | 11:59 AM San Antonio, N St Mary's St (Greyhound), TX | 27h46 | 4:45 PM Indianapolis, Illinois St (Greyhound Bus Station) | 2 transfers | |
FlixBus+ · | 9:55 PM San Antonio, N St Mary's St (Greyhound), TX | 30h00 | 4:55 AM Indianapolis, Illinois St (Greyhound Bus Station) | 2 transfers | |
FlixBus+ + FlixBus | 9:55 PM San Antonio, N St Mary's St (Greyhound), TX | 33h05 | 8:00 AM Indianapolis, IN | 2 transfers | |
| Saturday, October 24 | |||||
· · | 1:30 AM San Antonio, N St Mary's St (Greyhound), TX | 26h25 | 4:55 AM Indianapolis, Illinois St (Greyhound Bus Station) | 2 transfers | |
Find all the dates and times for this journey
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Indianapolis, IN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis, IN trip today.
World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.
Leading art museum set on the Newfields campus, with major collections from Europe, Asia, Africa, and America plus temporary exhibitions.
Museum and restored home of the 23rd U.S. president. Guided visits reveal politics, domestic life, and architecture from the late 1800s.
Pedestrian-friendly downtown canal lined with museums, public art, and boats. Ideal for a scenic walk and one of the city's most popular areas.
Historic city center surrounding the Soldiers and Sailors Monument. A signature urban space for architecture, events, and classic downtown views.
Popular cultural trail linking downtown districts with public art, bike lanes, and green streetscape design. Perfect for exploring the city on foot.
Indiana pork tenderloin sandwich is a breaded, fried cutlet served on a bun, often comically oversized. It is a beloved statewide classic common in Indianapolis pubs and diners.
Sugar cream pie is Indiana's state pie, made with cream, sugar, and nutmeg. Its simple farm-pantry origins make it a traditional Hoosier dessert tied closely to local identity.
Shrimp cocktail in Indianapolis style features chilled shrimp with very spicy tomato-horseradish sauce. St. Elmo made this fiery version a city dining icon.
Established fine-dining restaurant serving seasonal Midwestern cuisine with polished service. Known for refined plates and a warm, contemporary atmosphere.
Historic downtown steakhouse famous for aged steaks and the city's iconic fiery shrimp cocktail. Classic, upscale atmosphere with longstanding local prestige.
Long-running Indianapolis institution known for classic steaks, seafood, and old-school service. A traditional downtown choice with historic local character.
Moderate for a U.S. city: hotels and dining are mid-range, while transit is limited so many visitors use rideshare or rental cars.
Tip 18-20% at restaurants, $1-$2 per drink at bars, and 10-15% for taxis. Small cafe tips are appreciated but optional.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Indianapolis, IN.
Find answers to the most common questions about traveling from San Antonio, TX to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

Most San Antonio, TX to Indianapolis, IN buses use the San Antonio, N St Mary's St (Greyhound) to Indianapolis, Illinois St (Greyhound Bus Station) station pair. Use this guide to compare San Antonio, TX and Indianapolis, IN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
San Antonio, N St Mary's St (Greyhound) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Antonio, N St Mary's St (Greyhound). ATMs are available at San Antonio, N St Mary's St (Greyhound).
Ticket office support is available at San Antonio, N St Mary's St (Greyhound).
Available at San Antonio, N St Mary's St (Greyhound): Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, N St Mary's St (Greyhound): Limited accessibility features.
San Antonio, Avenue A / Pearl Pkwy is 2 km from San Antonio city centre. Public transport options include:
San Antonio, Avenue A / Pearl Pkwy has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Nearby Pearl Brewery offers dining options.
Wi-Fi is available at San Antonio, Avenue A / Pearl Pkwy. ATMs are available at San Antonio, Avenue A / Pearl Pkwy.
Ticket office support is available at San Antonio, Avenue A / Pearl Pkwy.
Available at San Antonio, Avenue A / Pearl Pkwy: Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, Avenue A / Pearl Pkwy: Accessible to wheelchair users.
Indianapolis, Illinois St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Fast food outlets are available.
Free Wi-Fi is available throughout the station. ATMs are aTM is located near the entrance.
Ticket office support is available at Indianapolis, Illinois St (Greyhound Bus Station).
Available at Indianapolis, Illinois St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Indianapolis, Illinois St (Greyhound Bus Station): The station is wheelchair accessible.
Check bus stations information for San Antonio, TX and Indianapolis, IN, including where buses depart and arrive on this route.
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