San Antonio, TX to Indianapolis, IN bus with Greyhound

Sat, Oct 24
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The cheapest and fastest buses from San Antonio, TX to Indianapolis, IN

Showing times, prices and bookable tickets for Oct 24

Cheapest price on Oct 24

$134

Average ticket price on Oct 24

$140

Fastest journey on Oct 24

1 d 2 h 25 m

Average journey duration on Oct 24

1 d 3 h 45 m

Buses on Oct 24

12

Distance

1609 km

Cheap tickets

The best way to find a cheap bus ticket from San Antonio, TX to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from San Antonio, TX to Indianapolis, IN will cost around $140 if you buy it on the day, but the cheapest tickets can be found for only $134.

Fast buses

It's difficult to get from San Antonio, TX to Indianapolis, IN without transferring at least 2 times.

  • Greyhound+FlixBusFlixBus+Greyhound
    4:20 AM28h10
    San Antonio, N St Mary's St (Greyhound), TX
    9:30 AMIndianapolis, Illinois St (Greyhound Bus Station)
    $1341One-way
    2 transfers
  • Greyhound · · +FlixBusFlixBus
    11:59 AM32h46
    San Antonio, N St Mary's St (Greyhound), TX
    9:45 PMIndianapolis, IN
    $1341One-way
    3 transfers
  • FlixBusFlixBus · FlixBus+Greyhound ·
    7:30 AM30h00
    San Antonio, N St Mary's St (Greyhound), TX
    2:30 PMIndianapolis, Illinois St (Greyhound Bus Station)
    $1341One-way
    3 transfers
  • FlixBusFlixBus · FlixBus+Greyhound ·
    7:45 AM29h45
    San Antonio, Avenue A / Pearl Pkwy, TX
    2:30 PMIndianapolis, Illinois St (Greyhound Bus Station)
    $1341One-way
    3 transfers
  • Greyhound · ·
    11:59 AM27h46
    San Antonio, N St Mary's St (Greyhound), TX
    4:45 PMIndianapolis, Illinois St (Greyhound Bus Station)
    $1341One-way
    2 transfers

Journey information

Overview: Bus from San Antonio, TX to Indianapolis, IN

USAUSA
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Icon of bus

Buses from San Antonio, TX to Indianapolis, IN run on average 10 times per day, taking around 26h 48m. Cheap bus tickets for this journey start at $114 (€96) if you book in advance.

The earliest bus runs at 01:30, the last at 23:55. The fastest bus covers the 999 miles (1609 km) distance in 23h 10m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
999 miles (1609 km)
Average bus duration
26h 48m
Cheapest ticket price
$114 (€96)
Buses per day
10
Fastest bus
23h 10m
First bus
1:30 AM
Last bus
11:55 PM
Cheapest Month
May
Cheapest Day
Fri
High Season
Jul - Sep
Low Season
Apr - Jun
Best time to book
70 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Frequently asked questions about your San Antonio, TX to Indianapolis, IN trip

Use these quick route answers to check fares, travel time, departure options, and direct services before booking from San Antonio, TX to Indianapolis, IN.

Cheap bus tickets from San Antonio, TX to Indianapolis, IN can start from as little as $114 (€96) when you book in advance. The average bus ticket price for San Antonio, TX to Indianapolis, IN is $218 (€183) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from San Antonio, TX to Indianapolis, IN leaves at 1:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Antonio, TX to Indianapolis, IN leaves at 11:55 PM.
There are 10 buses a day from San Antonio, TX to Indianapolis, IN which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.

San Antonio, TX to Indianapolis, IN Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
01:30AM
Arrival Time
08:00AM
Duration
29h30
Departure days
Everyday
Cheapest price
$133
Operator
Greyhound
Departure Time
04:20AM
Arrival Time
12:10PM
Duration
30h50
Departure days
Tue, Wed
Cheapest price
$133
Operator
FlixBus
Departure Time
04:20AM
Arrival Time
09:30AM
Duration
28h10
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
$126
Operator
Greyhound
Departure Time
07:30AM
Arrival Time
02:30PM
Duration
30h00
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
$133
Operator
FlixBus
Departure Time
07:45AM
Arrival Time
08:00AM
Duration
47h15
Departure days
Mon, Wed
Cheapest price
$131
Operator
Greyhound
Departure Time
07:45AM
Arrival Time
02:30PM
Duration
29h45
Departure days
Mon, Wed, Thu, Fri, Sat, Sun
Cheapest price
$132
Operator
Greyhound
Departure Time
09:45AM
Arrival Time
09:30AM
Duration
46h45
Departure days
Sat, Sun
Cheapest price
$127
Operator
FlixBus
Departure Time
09:45AM
Arrival Time
08:00AM
Duration
45h15
Departure days
Sat, Sun
Cheapest price
$126
Operator
Greyhound
Departure Time
11:59AM
Arrival Time
04:45PM
Duration
27h46
Departure days
Everyday
Cheapest price
$133
Operator
Greyhound
Departure Time
09:00PM
Arrival Time
04:55AM
Duration
30h55
Departure days
Wed, Thu
Cheapest price
$132
Operator
Greyhound
Departure Time
09:55PM
Arrival Time
04:55AM
Duration
30h00
Departure days
Mon, Tue, Fri, Sat, Sun
Cheapest price
$132

Live departures

San Antonio, TX to Indianapolis, IN bus times

The table below shows live departures for San Antonio, TX to Indianapolis, IN buses for today, Friday, October 23. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound+FlixBusFlixBus+Greyhound4:20 AM San Antonio, N St Mary's St (Greyhound), TX
28h10
9:30 AM Indianapolis, Illinois St (Greyhound Bus Station)2 transfers
Greyhound+FlixBusFlixBus · FlixBus4:20 AM San Antonio, N St Mary's St (Greyhound), TX
26h40
8:00 AM Indianapolis, IN2 transfers
FlixBusFlixBus · FlixBus+Greyhound · 7:30 AM San Antonio, N St Mary's St (Greyhound), TX
30h00
2:30 PM Indianapolis, Illinois St (Greyhound Bus Station)3 transfers
FlixBusFlixBus · FlixBus+Greyhound · 7:45 AM San Antonio, Avenue A / Pearl Pkwy, TX
29h45
2:30 PM Indianapolis, Illinois St (Greyhound Bus Station)3 transfers
FlixBusFlixBus · FlixBus+Greyhound+FlixBusFlixBus7:45 AM San Antonio, Avenue A / Pearl Pkwy, TX
38h30
11:15 PM Indianapolis, IN4 transfers
Greyhound · · +FlixBusFlixBus11:59 AM San Antonio, N St Mary's St (Greyhound), TX
32h46
9:45 PM Indianapolis, IN3 transfers
Greyhound · · 11:59 AM San Antonio, N St Mary's St (Greyhound), TX
27h46
4:45 PM Indianapolis, Illinois St (Greyhound Bus Station)2 transfers
FlixBusFlixBus+Greyhound · 9:55 PM San Antonio, N St Mary's St (Greyhound), TX
30h00
4:55 AM Indianapolis, Illinois St (Greyhound Bus Station)2 transfers
FlixBusFlixBus+Greyhound+FlixBusFlixBus9:55 PM San Antonio, N St Mary's St (Greyhound), TX
33h05
8:00 AM Indianapolis, IN2 transfers
Saturday, October 24
Greyhound · · 1:30 AM San Antonio, N St Mary's St (Greyhound), TX
26h25
4:55 AM Indianapolis, Illinois St (Greyhound Bus Station)2 transfers

Find all the dates and times for this journey

Why should you book San Antonio, TX to Indianapolis, IN buses with Omio?

Greyhound as well as FlixBus offer buses services from San Antonio, TX to Indianapolis, IN.
Omio is an official ticket reseller for all your travel options from San Antonio, TX to Indianapolis, IN.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from San Antonio, TX to Indianapolis, IN.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, flight and train to ensure you get the best deal for traveling from San Antonio, TX to Indianapolis, IN.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from San Antonio, TX to Indianapolis, IN.
  • Multiple modes of transport: Omio allows you to compare travel options including bus, flight and train to find the ideal travel option from San Antonio, TX to Indianapolis, IN.

Bus providers: Greyhound, FlixBus from San Antonio, TX to Indianapolis, INYou can travel by bus between San Antonio, TX to Indianapolis, IN with Greyhound, FlixBus for as low as $114 (€96). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
23h 10m
Cheapest FlixBus Price
$126 (€105)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
23h 45m
Cheapest Greyhound Price
$114 (€96)
Greyhound frequency
9 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Companies, tickets, and onboard amenities between San Antonio, TX and Indianapolis, IN

Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.

When taking a bus from San Antonio, TX to Indianapolis, IN, you can count on Greyhound, FlixBus for the best way to get you to Indianapolis, IN. You can also check all possible bus companies who offer a service between San Antonio, TX and Indianapolis, IN and compare the amenities they offer before buying a bus ticket.
Yes, there are bathrooms on board the bus from San Antonio, TX to Indianapolis, IN for bus company Greyhound, FlixBus.
Yes, the following accessibility options are available when taking the bus from San Antonio, TX to Indianapolis, IN:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Whether you can cancel your bus ticket from San Antonio, TX to Indianapolis, IN depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Yes, there is food available to purchase on board the bus from San Antonio, TX to Indianapolis, IN.
Yes, the following luggage options are included when booking a bus ticket from San Antonio, TX to Indianapolis, IN:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from San Antonio, TX to Indianapolis, IN:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from San Antonio, TX to Indianapolis, IN. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from San Antonio, TX to Indianapolis, IN with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from San Antonio, TX to Indianapolis, IN with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from San Antonio, TX to Indianapolis, IN with the following bus company: Greyhound, FlixBus.

Complete guide to Indianapolis, IN

Things to do in Indianapolis, IN

Discover the best of Indianapolis, IN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis, IN trip today.

  • Must visit

The Children's Museum of Indianapolis

World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.

  • Must visit

Indianapolis Museum of Art at Newfields

Leading art museum set on the Newfields campus, with major collections from Europe, Asia, Africa, and America plus temporary exhibitions.

  • Recommended

Benjamin Harrison Presidential Site

Museum and restored home of the 23rd U.S. president. Guided visits reveal politics, domestic life, and architecture from the late 1800s.

United States Dollar ($)

Moderate for a U.S. city: hotels and dining are mid-range, while transit is limited so many visitors use rideshare or rental cars.

Average meal costs

Budget
$10-$18 for fast food or a casual meal.
Mid-range
$20-$40 per person for a restaurant meal.
Fine dining
$60+ per person for upscale dining.
Coffee
$3-$6 for coffee or a cappuccino.

Tipping culture

Tip 18-20% at restaurants, $1-$2 per drink at bars, and 10-15% for taxis. Small cafe tips are appreciated but optional.

Plan your visit to Indianapolis, IN

Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Indianapolis, IN.

The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Indianapolis, travelers should be cautious of pickpocketing and vehicle break-ins, especially in busy areas like downtown and near major event venues. Common scams include overcharging by unofficial taxi or rideshare drivers and distraction tactics used to steal belongings. It's advised to use authorized transportation services, avoid poorly lit or unfamiliar areas at night, and keep valuables secure.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

FAQs: Bus from San Antonio, TX to Indianapolis, IN

Find answers to the most common questions about traveling from San Antonio, TX to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

FAQs
It's helpful to compare your options as there are 3 ways to travel between San Antonio, TX and Indianapolis, IN including taking a bus, flight, and train.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.

popular bus stations

Popular bus stations from San Antonio, TX to Indianapolis, IN

Most San Antonio, TX to Indianapolis, IN buses use the San Antonio, N St Mary's St (Greyhound) to Indianapolis, Illinois St (Greyhound Bus Station) station pair. Use this guide to compare San Antonio, TX and Indianapolis, IN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in San Antonio
Arrival bus stations in Indianapolis

Which San Antonio, TX station do buses to Indianapolis, IN leave from?

Buses from San Antonio, TX to Indianapolis, IN leave from San Antonio, N St Mary's St (Greyhound). The station is 0 miles (1 km) from San Antonio, TX city centre at 500 N St Mary's St, San Antonio, TX 78205, USA.
San Antonio, N St Mary's St (Greyhound)500 N St Mary's St, San Antonio, TX 78205, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to San Antonio, N St Mary's St (Greyhound) from San Antonio city centre

TRUE

San Antonio, N St Mary's St (Greyhound) bus station facilities and services

San Antonio, N St Mary's St (Greyhound) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at San Antonio, N St Mary's St (Greyhound). ATMs are available at San Antonio, N St Mary's St (Greyhound).

Tickets and information

Ticket office support is available at San Antonio, N St Mary's St (Greyhound).

Parking, taxis and toilets

Available at San Antonio, N St Mary's St (Greyhound): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at San Antonio, N St Mary's St (Greyhound): Limited accessibility features.

San Antonio, Avenue A / Pearl PkwyAvenue A & Pearl Pkwy, San Antonio, TX 78215, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to San Antonio, Avenue A / Pearl Pkwy from San Antonio city centre

San Antonio, Avenue A / Pearl Pkwy is 2 km from San Antonio city centre. Public transport options include:

BusFlixBus 2230 · 11m · $2
10, 14, 214, 9 · 12m · $3 · every ~17 min

San Antonio, Avenue A / Pearl Pkwy bus station facilities and services

San Antonio, Avenue A / Pearl Pkwy has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Nearby Pearl Brewery offers dining options.

Wi-Fi and ATMs

Wi-Fi is available at San Antonio, Avenue A / Pearl Pkwy. ATMs are available at San Antonio, Avenue A / Pearl Pkwy.

Tickets and information

Ticket office support is available at San Antonio, Avenue A / Pearl Pkwy.

Parking, taxis and toilets

Available at San Antonio, Avenue A / Pearl Pkwy: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at San Antonio, Avenue A / Pearl Pkwy: Accessible to wheelchair users.

Bus stations for San Antonio, TX to Indianapolis, IN

Check bus stations information for San Antonio, TX and Indianapolis, IN, including where buses depart and arrive on this route.

When departing from San Antonio, TX , you have various bus station options to start your journey from including San Antonio, N St Mary's St (Greyhound), San Antonio, Avenue A / Pearl Pkwy . When arriving in Indianapolis, IN , you can end your journey in bus stations like Indianapolis, Illinois St (Greyhound Bus Station) .Passengers board the bus most frequently from San Antonio, N St Mary's St (Greyhound), which is located around 0 miles (1 km) away from the city centre, and they get off the bus at Indianapolis, Illinois St (Greyhound Bus Station), located 1 away from the city centre.

More options for your journey from San Antonio, TX to Indianapolis, IN

Here are some other resources that might have the information you need

Most popular buses to and from Indianapolis, IN and San Antonio, TX

HomeBusesBuses in USABus tickets to Indianapolis, INSan Antonio, TX to Indianapolis, IN bus

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