- Must visit
The Children's Museum of Indianapolis
World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.
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The cheapest and fastest buses from San Antonio, TX to Indianapolis, IN
Showing times and prices for Jul 26
Cheapest price
$120
Average price
$130
Fastest journey
1 d 2 h 25 m
Average duration
1 d 4 h 26 m
Buses per day
12
Distance
1609 km
Cheap tickets
The best way to find a cheap bus ticket from San Antonio, TX to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to Indianapolis, IN will cost around $130 if you buy it on the day, but the cheapest tickets can be found for only $120.
Fast buses
It's difficult to get from San Antonio, TX to Indianapolis, IN without transferring at least 2 times.
· · 5:50 AM29h20San Antonio, N St Mary's St (Greyhound), TX12:10 PMIndianapolis, Illinois St (Greyhound Bus Station)$1201One-way2 transfers- · · 12:35 PM27h10San Antonio, N St Mary's St (Greyhound), TX4:45 PMIndianapolis, Illinois St (Greyhound Bus Station)$1211One-way2 transfers
- · · +
FlixBus12:35 PM32h10San Antonio, N St Mary's St (Greyhound), TX9:45 PMIndianapolis, E Washington St / N Delaware St (City/County Building), IN$1211One-way3 transfers - FlixBus+ · 9:55 PM30h00San Antonio, N St Mary's St (Greyhound), TX4:55 AMIndianapolis, Illinois St (Greyhound Bus Station)$1211One-way2 transfers
- FlixBus · FlixBus · FlixBus+9:45 AM46h45San Antonio, Avenue A / Pearl Pkwy, TX9:30 AMIndianapolis, Illinois St (Greyhound Bus Station)$1241One-way5 transfers
- · · 1:30 AM26h25San Antonio, N St Mary's St (Greyhound), TX4:55 AMIndianapolis, Illinois St (Greyhound Bus Station)$1621One-way2 transfers
- · · 12:35 PM27h10San Antonio, N St Mary's St (Greyhound), TX4:45 PMIndianapolis, Illinois St (Greyhound Bus Station)$1211One-way2 transfers
- · · 5:50 AM29h20San Antonio, N St Mary's St (Greyhound), TX12:10 PMIndianapolis, Illinois St (Greyhound Bus Station)$1201One-way2 transfers
- · +FlixBus1:30 AM29h30San Antonio, N St Mary's St (Greyhound), TX8:00 AMIndianapolis, E Washington St / N Delaware St (City/County Building), IN$1361One-way2 transfers
- FlixBus · FlixBus+ · 7:45 AM29h45San Antonio, Avenue A / Pearl Pkwy, TX2:30 PMIndianapolis, Illinois St (Greyhound Bus Station)$1271One-way3 transfers
Travel Information
Compare bus, flight, and train for San Antonio, TX to Indianapolis, IN
Omio recommends booking the bus as it is the most popular option from San Antonio, TX to Indianapolis, IN among Omio's users. If you are prioritising price take the bus with prices starting from $96. For those with little time consider booking a flight which can get you there in 4h 48m. The ticket price range depends on the travel mode: a bus costs an average of $96, and a flight costs an average of $170.
Distance: 999 miles (1609 km)
Compare bus with
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$187 Average price Cheapest | $323 Average price | $187 Average price | $190 Average price (fuel + tolls) |
24h 47m Average total duration 24h 17m Onboard + 30m Additional time* | 7h 48m Average total duration Fastest 4h 48m Onboard + 3h 0m Additional time* | 31h 55m Average total duration 31h 25m Onboard + 30m Additional time* | 17h 10m Average total duration (door-to-door) |
Most popular bus company |  Most popular airline |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from San Antonio, TX to Indianapolis, IN is a bus with an average price of $187 (€187).
This is compared to other travel options from San Antonio, TX to Indianapolis, IN:
A bus is $0.35 (€0.35) less than a train for this route with tickets for a train from San Antonio, TX to Indianapolis, IN costing on average $187 (€187).
A bus is $136 (€136) less than a flight for this route with tickets for a flight from San Antonio, TX to Indianapolis, IN costing on average $323 (€323).
The fastest way to travel from San Antonio, TX to Indianapolis, IN is by flight with an average journey time of 4h 48m.
Other travel options to Indianapolis, IN take longer:
Bus takes on average 24h 17m.
Train takes on average 31h 25m.
It's helpful to compare your options as there are 3 ways to travel between San Antonio, TX and Indianapolis, IN including taking a bus, flight, and train.
We recommend using the bus as it is the most popular way to get from San Antonio, TX to Indianapolis, IN among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
San Antonio, TX to Indianapolis, IN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:15AM | Arrival Time 01:25PM | Duration 36h10 | Departure days Wed | Cheapest price $189 |
Operator Greyhound | Departure Time 01:30AM | Arrival Time 04:55AM | Duration 26h25 | Departure days Fri, Sun | Cheapest price $122 |
Operator Greyhound | Departure Time 05:50AM | Arrival Time 12:10PM | Duration 29h20 | Departure days Fri, Sun | Cheapest price $112 |
Operator Greyhound | Departure Time 06:30AM | Arrival Time 06:35PM | Duration 36h05 | Departure days Wed | Cheapest price $96 |
Operator Greyhound | Departure Time 07:30AM | Arrival Time 02:30PM | Duration 30h00 | Departure days Fri, Sun | Cheapest price $122 |
Operator Greyhound | Departure Time 07:45AM | Arrival Time 02:30PM | Duration 29h45 | Departure days Fri, Sun | Cheapest price $122 |
Operator FlixBus | Departure Time 09:45AM | Arrival Time 09:30AM | Duration 46h45 | Departure days Sun | Cheapest price $124 |
Operator Greyhound | Departure Time 12:35PM | Arrival Time 09:45PM | Duration 32h10 | Departure days Fri, Sun | Cheapest price $112 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 12:25PM | Duration 47h40 | Departure days Thu, Sat | Cheapest price $239 |
Operator Greyhound | Departure Time 12:45PM | Arrival Time 03:20AM | Duration 38h35 | Departure days Mon | Cheapest price $150 |
Operator Greyhound | Departure Time 06:35PM | Arrival Time 09:35PM | Duration 27h00 | Departure days Thu | Cheapest price $171 |
Operator Greyhound | Departure Time 09:55PM | Arrival Time 08:00AM | Duration 33h05 | Departure days Fri, Sun | Cheapest price $112 |
Live departures
San Antonio, TX to Indianapolis, IN bus times
The table below shows live departures for San Antonio, TX to Indianapolis, IN buses for today, Saturday, July 25. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · · | 1:30 AM San Antonio, N St Mary's St (Greyhound), TX | 26h25 | 4:55 AM Indianapolis, Illinois St (Greyhound Bus Station) | 2 transfers | |
| · +FlixBus | 1:30 AM San Antonio, N St Mary's St (Greyhound), TX | 29h30 | 8:00 AM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 2 transfers | |
| · · | 5:50 AM San Antonio, N St Mary's St (Greyhound), TX | 29h20 | 12:10 PM Indianapolis, Illinois St (Greyhound Bus Station) | 2 transfers | |
| FlixBus · FlixBus+ · | 7:30 AM San Antonio, N St Mary's St (Greyhound), TX | 30h00 | 2:30 PM Indianapolis, Illinois St (Greyhound Bus Station) | 3 transfers | |
| FlixBus · FlixBus+ · | 7:45 AM San Antonio, Avenue A / Pearl Pkwy, TX | 29h45 | 2:30 PM Indianapolis, Illinois St (Greyhound Bus Station) | 3 transfers | |
| FlixBus · FlixBus++FlixBus | 7:45 AM San Antonio, Avenue A / Pearl Pkwy, TX | 38h30 | 11:15 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 4 transfers | |
| FlixBus · FlixBus · FlixBus+ | 9:45 AM San Antonio, Avenue A / Pearl Pkwy, TX | 46h45 | 9:30 AM Indianapolis, Illinois St (Greyhound Bus Station) | 5 transfers | |
| FlixBus · FlixBus · FlixBus+ | 9:45 AM San Antonio, Avenue A / Pearl Pkwy, TX | 45h15 | 8:00 AM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 5 transfers | |
| · · | 12:35 PM San Antonio, N St Mary's St (Greyhound), TX | 27h10 | 4:45 PM Indianapolis, Illinois St (Greyhound Bus Station) | 2 transfers | |
| · · +FlixBus | 12:35 PM San Antonio, N St Mary's St (Greyhound), TX | 32h10 | 9:45 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 3 transfers | |
Find all the dates and times for this journey
Compare prices and tickets San Antonio, TX to Indianapolis, IN by bus, flight, or train
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book San Antonio, TX to Indianapolis, IN buses with Omio?
Greyhound operates all buses services from San Antonio, TX to Indianapolis, IN.
Omio is an official ticket reseller for all your travel options from San Antonio, TX to Indianapolis, IN.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, flight and train to ensure you get the best deal for traveling from San Antonio, TX to Indianapolis, IN.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, flight and train to find the ideal travel option from San Antonio, TX to Indianapolis, IN.
Journey information
Overview: Bus from San Antonio, TX to Indianapolis, IN
USAUSA
Buses from San Antonio, TX to Indianapolis, IN run on average 10 times per day, taking around 24h 17m. Cheap bus tickets for this journey start at $96 (€96) if you book in advance.
The earliest bus runs at 01:30, the last at 23:55. The fastest bus covers the 999 miles (1609 km) distance in 27h 0m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 999 miles (1609 km) |
Average bus duration 24h 17m |
Cheapest ticket price $96 (€96) |
Buses per day 10 |
Fastest bus 27h 0m |
First bus 1:30 AM |
Last bus 11:55 PM |
Cheapest Month Sep |
Cheapest Day Fri |
High Season Oct - Dec |
Low Season Jul - Sep |
Best time to book 70 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from San Antonio, TX to Indianapolis, INYou can travel by bus between San Antonio, TX to Indianapolis, IN with Greyhound for as low as $96 (€96). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
27h 0m
Cheapest Price
$96 (€96)
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Indianapolis, IN
Things to do in Indianapolis, IN
Discover the best of Indianapolis, IN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis, IN trip today.
- Must visit
Indianapolis Museum of Art at Newfields
Leading art museum set on the Newfields campus, with major collections from Europe, Asia, Africa, and America plus temporary exhibitions.
- Recommended
Benjamin Harrison Presidential Site
Museum and restored home of the 23rd U.S. president. Guided visits reveal politics, domestic life, and architecture from the late 1800s.
- Must visit
Central Canal
Pedestrian-friendly downtown canal lined with museums, public art, and boats. Ideal for a scenic walk and one of the city's most popular areas.
- Must visit
Monument Circle
Historic city center surrounding the Soldiers and Sailors Monument. A signature urban space for architecture, events, and classic downtown views.
- Must visit
Indianapolis Cultural Trail
Popular cultural trail linking downtown districts with public art, bike lanes, and green streetscape design. Perfect for exploring the city on foot.
Pork Tenderloin Sandwich
Indiana pork tenderloin sandwich is a breaded, fried cutlet served on a bun, often comically oversized. It is a beloved statewide classic common in Indianapolis pubs and diners.
- Vegetarian
Sugar Cream Pie
Sugar cream pie is Indiana's state pie, made with cream, sugar, and nutmeg. Its simple farm-pantry origins make it a traditional Hoosier dessert tied closely to local identity.
- Gluten-free
St. Elmo-Style Shrimp Cocktail
Shrimp cocktail in Indianapolis style features chilled shrimp with very spicy tomato-horseradish sauce. St. Elmo made this fiery version a city dining icon.
Vida
Established fine-dining restaurant serving seasonal Midwestern cuisine with polished service. Known for refined plates and a warm, contemporary atmosphere.
St. Elmo Steak House
Historic downtown steakhouse famous for aged steaks and the city's iconic fiery shrimp cocktail. Classic, upscale atmosphere with longstanding local prestige.
Harry & Izzy's
Long-running Indianapolis institution known for classic steaks, seafood, and old-school service. A traditional downtown choice with historic local character.
United States Dollar ($)
Moderate for a U.S. city: hotels and dining are mid-range, while transit is limited so many visitors use rideshare or rental cars.
Average meal costs
- Budget
- $10-$18 for fast food or a casual meal.
- Mid-range
- $20-$40 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-$6 for coffee or a cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-$2 per drink at bars, and 10-15% for taxis. Small cafe tips are appreciated but optional.
FAQs: Bus from San Antonio, TX to Indianapolis, IN
Find answers to the most common questions about traveling from San Antonio, TX to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.
Cheap bus tickets from San Antonio, TX to Indianapolis, IN can start from as little as $96 (€96) when you book in advance. The average bus ticket price for San Antonio, TX to Indianapolis, IN is $187 (€187) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Antonio, TX to Indianapolis, IN is 27h 0m to travel the 999 miles (1609 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from San Antonio, TX to Indianapolis, IN leaves at 1:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Antonio, TX to Indianapolis, IN leaves at 11:55 PM.
There are 10 buses a day from San Antonio, TX to Indianapolis, IN which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Antonio, TX to Indianapolis, IN, you can count on Greyhound for the best way to get you to Indianapolis, IN. You can also check all possible bus companies who offer a service between San Antonio, TX and Indianapolis, IN and compare the amenities they offer before buying a bus ticket.
A trip to Indianapolis, IN from San Antonio, TX is worth doing but not as a day trip with a journey time of 27h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from San Antonio, TX to Indianapolis, IN is September.
It's helpful to compare your options as there are 3 ways to travel between San Antonio, TX and Indianapolis, IN including taking a bus, flight, and train.
Yes, the following accessibility options are available when taking the bus from San Antonio, TX to Indianapolis, IN:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from San Antonio, TX to Indianapolis, IN for bus company Greyhound.
Some of the most interesting sights to explore in Indianapolis, IN are:
- Indianapolis Motor Speedway, a historic racing circuit known for hosting the Indianapolis 500
- The Children's Museum of Indianapolis, the world's largest children's museum featuring interactive exhibits
- Indianapolis Zoo, a popular attraction with diverse animal exhibits and a botanical garden
- Indiana State Museum, showcasing the state's history, art, and science through various exhibits
- White River State Park, a sprawling urban park offering trails, gardens, and cultural attractions.
The best things to do in Indianapolis, IN include:
- Indianapolis Museum of Art at Newfields, a vast art museum with extensive collections and beautiful gardens
- Attend a race at the Indianapolis Motor Speedway, home of the iconic Indy 500
- Explore the interactive exhibits and educational programs at The Children's Museum of Indianapolis
- Visit the dolphin pavilion and animal habitats at the Indianapolis Zoo
- Enjoy a walk along the canal and cultural attractions at White River State Park.
Whether you can cancel your bus ticket from San Antonio, TX to Indianapolis, IN depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from San Antonio, TX to Indianapolis, IN.
Yes, the following luggage options are included when booking a bus ticket from San Antonio, TX to Indianapolis, IN:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from San Antonio, TX to Indianapolis, IN:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from San Antonio, TX to Indianapolis, IN.
You can reserve your seat on the bus from San Antonio, TX to Indianapolis, IN with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from San Antonio, TX to Indianapolis, IN with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from San Antonio, TX to Indianapolis, IN with the following bus company: Greyhound.
Since neither San Antonio, TX nor Indianapolis, IN are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from San Antonio, TX to Indianapolis, IN among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Indianapolis, travelers should be cautious of pickpocketing and vehicle break-ins, especially in busy areas like downtown and near major event venues. Common scams include overcharging by unofficial taxi or rideshare drivers and distraction tactics used to steal belongings. It's advised to use authorized transportation services, avoid poorly lit or unfamiliar areas at night, and keep valuables secure.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from San Antonio, TX to Indianapolis, IN
Most San Antonio, TX to Indianapolis, IN buses use the San Antonio, N St Mary's St (Greyhound) to Indianapolis, Illinois St (Greyhound Bus Station) station pair, with some services arriving at Indianapolis, E Washington St / N Delaware St (City/County Building). Use this guide to compare San Antonio, TX and Indianapolis, IN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in San Antonio
Arrival bus stations in Indianapolis
San Antonio, N St Mary's St (Greyhound)
San Antonio, Avenue A / Pearl Pkwy
City-centre transport
Getting to San Antonio, Avenue A / Pearl Pkwy from San Antonio city centre
BusFlixBus 2230 · 11m · $1
10, 14, 214, 9 · 12m · $2 · every ~17 min
Indianapolis, Illinois St (Greyhound Bus Station)
Indianapolis, E Washington St / N Delaware St (City/County Building)
Most popular bus connections from San Antonio, TX
More options for your journey from San Antonio, TX to Indianapolis, IN
Here are some other resources that might have the information you need
Most popular buses to and from Indianapolis, IN and San Antonio, TX
Most popular bus connections to Indianapolis, IN
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