- Must visit
The Children's Museum of Indianapolis
The world's largest children's museum, known for immersive science, history, and culture exhibits for all ages.
Cheapest price
$60
Average price
$102
Fastest journey
5 h 40 m
Average duration
6 h
Buses per day
12
Distance
392 km
The best way to find a cheap bus ticket from Milwaukee, WI to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milwaukee, WI to Indianapolis, IN will cost around $102 if you buy it on the day, but the cheapest tickets can be found for only $60.
Of the 12 buses that leave Milwaukee, WI for Indianapolis, IN on Fri, Jun 05, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jun 05 the direct buses cover the 392 km distance in an average of 6 h but if you time it right, some buses will get you there in just 5 h 40 m .
On Fri, Jun 05 the slowest buses will take 6 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
·
FlixBus+
FlixBus
FlixBus+
FlixBus
· Omio recommends booking the bus as it is the most popular option from Milwaukee, WI to Indianapolis, IN among Omio's users. If you are prioritising price take the bus with prices starting from $35. For those with little time consider booking a flight which can get you there in 4h 50m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.4 - 1.0kg. The ticket price range depends on the travel mode: a bus costs an average of $35, and a flight costs an average of $139.
Distance: 243 miles (392 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$70 Average price Cheapest | $84 Average price | $310 Average price | $64 Average price (fuel + tolls) |
6h 12m Average total duration 5h 42m Onboard + 30m Additional time* | 6h 52m Average total duration 6h 22m Onboard + 30m Additional time* | 7h 50m Average total duration Fastest 4h 50m Onboard + 3h 0m Additional time* | 4h 6m Average total duration (door-to-door) |
0.4 - 1.0kg CO2 emissions Lowest | - CO2 emissions | 1.2 - 2.3kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Milwaukee, WI to Indianapolis, IN:
A bus is $14 (€11) less than a train for this route with tickets for a train from Milwaukee, WI to Indianapolis, IN costing on average $84 (€68).
A bus is $240 (€194) less than a flight for this route with tickets for a flight from Milwaukee, WI to Indianapolis, IN costing on average $310 (€250).
Other travel options to Indianapolis, IN take longer:
Bus takes on average 5h 42m.
Train takes on average 6h 22m.
You'll arrive about -2h -36m sooner (5h 42m by bus vs 4h 6m by car) and save roughly $-5.40 (€-4.36) compared to fuel and tolls ($70 (€56) vs $64 (€52)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by FlixBus.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Amtrak | Departure Time 12:35AM | Arrival Time 06:55AM | Duration 6h20 | Departure days Mon, Wed, Thu, Sun | Cheapest price $86 |
Operator Greyhound | Departure Time 12:55AM | Arrival Time 08:15AM | Duration 7h20 | Departure days Wed, Thu | Cheapest price $68 |
Operator Greyhound | Departure Time 01:05AM | Arrival Time 08:15AM | Duration 7h10 | Departure days Sun | Cheapest price $85 |
Operator Greyhound | Departure Time 01:55AM | Arrival Time 09:15AM | Duration 7h20 | Departure days Thu | Cheapest price $67 |
Operator FlixBus | Departure Time 03:25AM | Arrival Time 11:50AM | Duration 7h25 | Departure days Thu, Fri | Cheapest price $101 |
Operator Greyhound | Departure Time 03:25AM | Arrival Time 10:45AM | Duration 6h20 | Departure days Thu, Fri | Cheapest price $101 |
Operator Greyhound | Departure Time 06:30AM | Arrival Time 03:05PM | Duration 7h35 | Departure days Thu, Fri | Cheapest price $109 |
Operator FlixBus | Departure Time 06:30AM | Arrival Time 03:00PM | Duration 7h30 | Departure days Thu, Fri | Cheapest price $109 |
Operator Greyhound | Departure Time 08:25AM | Arrival Time 02:45PM | Duration 6h20 | Departure days Sun | Cheapest price $66 |
Operator FlixBus | Departure Time 08:25AM | Arrival Time 04:55PM | Duration 8h30 | Departure days Wed | Cheapest price $84 |
Operator FlixBus | Departure Time 09:00AM | Arrival Time 04:10PM | Duration 6h10 | Departure days Fri | Cheapest price $60 |
Operator FlixBus | Departure Time 09:20AM | Arrival Time 04:10PM | Duration 5h50 | Departure days Fri | Cheapest price $60 |
Operator Greyhound | Departure Time 11:50AM | Arrival Time 06:50PM | Duration 6h00 | Departure days Fri | Cheapest price $99 |
Operator Greyhound | Departure Time 12:10PM | Arrival Time 06:50PM | Duration 5h40 | Departure days Fri | Cheapest price $100 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 08:10PM | Duration 6h10 | Departure days Mon, Sun | Cheapest price $35 |
Operator FlixBus | Departure Time 02:20PM | Arrival Time 08:10PM | Duration 5h50 | Departure days Mon, Tue, Sat | Cheapest price $43 |
Operator FlixBus | Departure Time 03:00PM | Arrival Time 09:10PM | Duration 6h10 | Departure days Mon, Sat | Cheapest price $40 |
Operator FlixBus | Departure Time 03:20PM | Arrival Time 09:10PM | Duration 5h50 | Departure days Tue, Thu, Fri | Cheapest price $60 |
Operator FlixBus | Departure Time 03:40PM | Arrival Time 11:20PM | Duration 6h40 | Departure days Thu, Fri | Cheapest price $66 |
Operator Amtrak | Departure Time 07:35PM | Arrival Time 04:15AM | Duration 7h40 | Departure days Thu | Cheapest price $94 |
Operator Amtrak | Departure Time 07:45PM | Arrival Time 04:15AM | Duration 7h30 | Departure days Thu | Cheapest price $94 |
Operator Greyhound | Departure Time 07:55PM | Arrival Time 04:15AM | Duration 7h20 | Departure days Thu, Fri | Cheapest price $82 |
Operator Greyhound | Departure Time 08:05PM | Arrival Time 04:15AM | Duration 7h10 | Departure days Thu, Fri | Cheapest price $82 |
Operator FlixBus | Departure Time 09:40PM | Arrival Time 04:20AM | Duration 6h40 | Departure days Mon | Cheapest price $87 |
The table below shows live departures for Milwaukee, WI to Indianapolis, IN buses for today, Thursday, June 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 3:20 PM Milwaukee, Intermodal Station | 7h45 | 12:05 AM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 1 transfer | |
FlixBus · FlixBus | 3:40 PM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI | 7h25 | 12:05 AM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 1 transfer | |
342 Hiawatha Service · 8856 AMTRAK | 7:35 PM Milwaukee Intermodal Station, Milwaukee, WI | 7h40 | 4:15 AM Indianapolis Station, Indianapolis, IN | 1 transfer | |
342 Hiawatha Service · 8856 AMTRAK | 7:45 PM Airport Amtrak Station, Milwaukee, WI | 7h30 | 4:15 AM Indianapolis Station, Indianapolis, IN | 1 transfer | |
· | 7:55 PM Milwaukee, Intermodal Station | 7h20 | 4:15 AM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
FlixBus+![]() | 8:05 PM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI | 7h10 | 4:15 AM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
| Friday, June 5 | |||||
FlixBus+![]() | 3:25 AM Milwaukee, Intermodal Station | 7h25 | 11:50 AM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 1 transfer | |
· | 3:25 AM Milwaukee, Intermodal Station | 6h20 | 10:45 AM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
· | 6:30 AM Milwaukee, Intermodal Station | 7h35 | 3:05 PM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
FlixBus+![]() | 6:30 AM Milwaukee, Intermodal Station | 7h30 | 3:00 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 1 transfer | |
FlixBus | 9:00 AM Milwaukee, Intermodal Station | 6h10 | 4:10 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 0 transfersDirect | |
FlixBus | 9:20 AM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI | 5h50 | 4:10 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 0 transfersDirect | |
FlixBus+![]() | 11:50 AM Milwaukee, Intermodal Station | 6h00 | 6:50 PM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
FlixBus+![]() | 12:10 PM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI | 5h40 | 6:50 PM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Milwaukee, WI to Indianapolis, IN run on average 12 times per day, taking around 5h 42m. Cheap bus tickets for this journey start at $35 (€29) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:05, the last at 23:15. The fastest bus covers the 243 miles (392 km) distance in 5h 40m.
Distance 243 miles (392 km) |
Average bus duration 5h 42m |
Cheapest ticket price $35 (€29) |
Buses per day 12 |
Direct buses 1 |
Fastest bus 5h 40m |
First bus 12:05 AM |
Last bus 11:15 PM |
Cheapest Month Jun |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Tue |
Least Busy Day Thu |
Best time to book 14 days |
Discover the best of Indianapolis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis trip today.
The world's largest children's museum, known for immersive science, history, and culture exhibits for all ages.
A major art campus featuring the Indianapolis Museum of Art, gardens, and rotating exhibitions in a scenic setting.
A must for racing fans, with historic cars, Indianapolis 500 artifacts, and motorsport heritage.
Downtown's central circle and gathering place, lined with historic buildings and anchored by the city's iconic monument.
Major urban park linking museums, trails, green space, and canal-side walks in the heart of the city.
Trendy cultural district known for independent shops, theaters, murals, and strong day-to-night energy.
A Hoosier classic: a breaded and fried pork cutlet served on a bun, often much larger than the bread. It is one of Central Indiana's most iconic comfort foods.
Indianapolis is famous for steakhouse-style shrimp cocktail topped with very spicy cocktail sauce, especially associated with old-school downtown dining.
Often called Hoosier pie, this simple custard-like pie made with cream, sugar, and flour is one of Indiana's signature desserts.
Historic downtown steakhouse best known for dry-aged steaks and its legendary spicy shrimp cocktail. Classic, upscale, and one of Indianapolis's most famous dining rooms.
Well-regarded New American restaurant in Fletcher Place, known for seasonal menus, thoughtful cocktails, and a stylish neighborhood setting.
Historic no-frills tavern famous for old-school burgers and a classic local atmosphere. A beloved casual stop with deep Indianapolis roots.
Moderate by U.S. city standards. Hotels vary by events, while casual dining, coffee, and transport are generally manageable.
Tip 18-20% in restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis 10-15%, hotel staff USD 2-5, and round up for casual services.
Find answers to the most common questions about traveling from Milwaukee, WI to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need