- Must visit
The Children's Museum of Indianapolis
World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.
Cheapest price
$54
Average price
$79
Fastest journey
5 h 50 m
Average duration
6 h 19 m
Buses per day
13
Distance
392 km
The best way to find a cheap bus ticket from Milwaukee, WI to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milwaukee, WI to Indianapolis, IN will cost around $79 if you buy it on the day, but the cheapest tickets can be found for only $54.
Of the 13 buses that leave Milwaukee, WI for Indianapolis, IN on Wed, Jul 22, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jul 22 the direct buses cover the 392 km distance in an average of 6 h 19 m but if you time it right, some buses will get you there in just 5 h 50 m .
On Wed, Jul 22 the slowest buses will take 6 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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· Omio recommends booking the bus as it is the most popular option from Milwaukee, WI to Indianapolis, IN among Omio's users. If you are prioritising price take the bus with prices starting from $35. For those with little time consider booking a flight which can get you there in 4h 50m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.4 - 1.0kg. The ticket price range depends on the travel mode: a bus costs an average of $35, and a flight costs an average of $136.
Distance: 243 miles (392 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$68 Average price Cheapest | $82 Average price | $304 Average price | $63 Average price (fuel + tolls) |
6h 12m Average total duration 5h 42m Onboard + 30m Additional time* | 6h 52m Average total duration 6h 22m Onboard + 30m Additional time* | 7h 50m Average total duration Fastest 4h 50m Onboard + 3h 0m Additional time* | 4h 6m Average total duration (door-to-door) |
0.4 - 1.0kg CO2 emissions Lowest | - CO2 emissions | 1.2 - 2.3kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Milwaukee, WI to Indianapolis, IN:
A bus is $14 (€11) less than a train for this route with tickets for a train from Milwaukee, WI to Indianapolis, IN costing on average $82 (€68).
A bus is $236 (€194) less than a flight for this route with tickets for a flight from Milwaukee, WI to Indianapolis, IN costing on average $304 (€250).
Other travel options to Indianapolis, IN take longer:
Bus takes on average 5h 42m.
Train takes on average 6h 22m.
You'll arrive about -2h -36m sooner (5h 42m by bus vs 4h 6m by car) and save roughly $-5.30 (€-4.36) compared to fuel and tolls ($68 (€56) vs $63 (€52)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by FlixBus.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Amtrak | Departure Time 12:35AM | Arrival Time 06:55AM | Duration 6h20 | Departure days Sun | Cheapest price $88 |
Operator Greyhound | Departure Time 01:05AM | Arrival Time 08:15AM | Duration 7h10 | Departure days Sun | Cheapest price $83 |
Operator FlixBus | Departure Time 03:25AM | Arrival Time 11:50AM | Duration 7h25 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $50 |
Operator Greyhound | Departure Time 03:25AM | Arrival Time 10:45AM | Duration 6h20 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $50 |
Operator Amtrak | Departure Time 06:15AM | Arrival Time 03:05PM | Duration 7h50 | Departure days Mon, Wed | Cheapest price $84 |
Operator Amtrak | Departure Time 06:26AM | Arrival Time 03:05PM | Duration 7h39 | Departure days Mon, Wed | Cheapest price $84 |
Operator Greyhound | Departure Time 06:30AM | Arrival Time 03:05PM | Duration 7h35 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $70 |
Operator FlixBus | Departure Time 06:30AM | Arrival Time 03:00PM | Duration 7h30 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $61 |
Operator FlixBus | Departure Time 09:00AM | Arrival Time 04:10PM | Duration 6h10 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $43 |
Operator FlixBus | Departure Time 09:20AM | Arrival Time 04:10PM | Duration 5h50 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $43 |
Operator Greyhound | Departure Time 11:50AM | Arrival Time 06:50PM | Duration 6h00 | Departure days Mon, Tue, Fri, Sun | Cheapest price $49 |
Operator Greyhound | Departure Time 12:10PM | Arrival Time 06:50PM | Duration 5h40 | Departure days Mon, Tue, Fri, Sun | Cheapest price $49 |
Operator FlixBus | Departure Time 02:20PM | Arrival Time 08:10PM | Duration 5h50 | Departure days Sat | Cheapest price $71 |
Operator FlixBus | Departure Time 03:00PM | Arrival Time 09:10PM | Duration 6h10 | Departure days Sat | Cheapest price $39 |
Operator FlixBus | Departure Time 03:20PM | Arrival Time 11:15PM | Duration 6h55 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $50 |
Operator FlixBus | Departure Time 03:40PM | Arrival Time 11:15PM | Duration 6h35 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $49 |
Operator Amtrak | Departure Time 05:44PM | Arrival Time 04:15AM | Duration 9h31 | Departure days Mon, Sun | Cheapest price $103 |
Operator Amtrak | Departure Time 05:55PM | Arrival Time 04:15AM | Duration 9h20 | Departure days Mon, Sun | Cheapest price $103 |
Operator Amtrak | Departure Time 07:35PM | Arrival Time 04:15AM | Duration 7h40 | Departure days Mon, Wed, Thu, Sun | Cheapest price $84 |
Operator Amtrak | Departure Time 07:45PM | Arrival Time 04:15AM | Duration 7h30 | Departure days Mon, Wed, Sun | Cheapest price $84 |
Operator Greyhound | Departure Time 08:35PM | Arrival Time 04:15AM | Duration 6h40 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $56 |
The table below shows live departures for Milwaukee, WI to Indianapolis, IN buses for today, Tuesday, July 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 3:25 AM Milwaukee, Intermodal Station | 6h20 | 10:45 AM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
+ FlixBus | 3:25 AM Milwaukee, Intermodal Station | 7h25 | 11:50 AM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 1 transfer | |
+ FlixBus | 6:30 AM Milwaukee, Intermodal Station | 7h30 | 3:00 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 1 transfer | |
· | 6:30 AM Milwaukee, Intermodal Station | 7h35 | 3:05 PM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
FlixBus | 9:00 AM Milwaukee, Intermodal Station | 6h10 | 4:10 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 0 transfersDirect | |
FlixBus | 9:20 AM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI | 5h50 | 4:10 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 0 transfersDirect | |
FlixBus+![]() | 11:50 AM Milwaukee, Intermodal Station | 6h00 | 6:50 PM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
FlixBus+![]() | 12:10 PM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI | 5h40 | 6:50 PM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
FlixBus · FlixBus | 3:20 PM Milwaukee, Intermodal Station | 6h55 | 11:15 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 1 transfer | |
FlixBus · FlixBus | 3:40 PM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI | 6h35 | 11:15 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 1 transfer | |
· | 8:35 PM Milwaukee, Intermodal Station | 6h40 | 4:15 AM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Milwaukee, WI to Indianapolis, IN run on average 12 times per day, taking around 5h 42m. Cheap bus tickets for this journey start at $35 (€29) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:05, the last at 23:15. The fastest bus covers the 243 miles (392 km) distance in 5h 40m.
Distance 243 miles (392 km) |
Average bus duration 5h 42m |
Cheapest ticket price $35 (€29) |
Buses per day 12 |
Direct buses 1 |
Fastest bus 5h 40m |
First bus 12:05 AM |
Last bus 11:15 PM |
Cheapest Month Jun |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Tue |
Least Busy Day Thu |
Best time to book 14 days |
Discover the best of Indianapolis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis trip today.
World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.
Leading art museum set on the Newfields campus, with major collections from Europe, Asia, Africa, and America plus temporary exhibitions.
Museum and restored home of the 23rd U.S. president. Guided visits reveal politics, domestic life, and architecture from the late 1800s.
Pedestrian-friendly downtown canal lined with museums, public art, and boats. Ideal for a scenic walk and one of the city's most popular areas.
Historic city center surrounding the Soldiers and Sailors Monument. A signature urban space for architecture, events, and classic downtown views.
Popular cultural trail linking downtown districts with public art, bike lanes, and green streetscape design. Perfect for exploring the city on foot.
Indiana pork tenderloin sandwich is a breaded, fried cutlet served on a bun, often comically oversized. It is a beloved statewide classic common in Indianapolis pubs and diners.
Sugar cream pie is Indiana's state pie, made with cream, sugar, and nutmeg. Its simple farm-pantry origins make it a traditional Hoosier dessert tied closely to local identity.
Shrimp cocktail in Indianapolis style features chilled shrimp with very spicy tomato-horseradish sauce. St. Elmo made this fiery version a city dining icon.
Established fine-dining restaurant serving seasonal Midwestern cuisine with polished service. Known for refined plates and a warm, contemporary atmosphere.
Historic downtown steakhouse famous for aged steaks and the city's iconic fiery shrimp cocktail. Classic, upscale atmosphere with longstanding local prestige.
Long-running Indianapolis institution known for classic steaks, seafood, and old-school service. A traditional downtown choice with historic local character.
Moderate for a U.S. city: hotels and dining are mid-range, while transit is limited so many visitors use rideshare or rental cars.
Tip 18-20% at restaurants, $1-$2 per drink at bars, and 10-15% for taxis. Small cafe tips are appreciated but optional.
Find answers to the most common questions about traveling from Milwaukee, WI to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

Most Milwaukee, WI to Indianapolis, IN buses use the Milwaukee, Intermodal Station to Indianapolis, Illinois St (Greyhound Bus Station) station pair, with some services arriving at Indianapolis, E Washington St / N Delaware St (City/County Building). Use this guide to compare Milwaukee, WI and Indianapolis, IN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need