- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Cheapest price
€67
Average price
€70
Fastest journey
9 h 20 m
Average duration
12 h 18 m
Buses per day
3
Distance
324 km
The best way to find a cheap bus ticket from Greenville, SC to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Charleston, SC will cost around €70 if you buy it on the day, but the cheapest tickets can be found for only €67.
It's difficult to get from Greenville, SC to Charleston, SC without transferring at least once.
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· Omio recommends booking the flight as it is the most popular option from Greenville, SC to Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from €62. For those with little time consider booking a flight which can get you there in 2h 28m. The ticket price range depends on the travel mode: a bus costs an average of €62, and a train costs an average of €220.
Distance: 201 miles (324 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
€113 Average price Cheapest | €298 Average price | €394 Average price | €35 Average price (fuel + tolls) |
12h 10m Average total duration 11h 40m Onboard + 30m Additional time* | 5h 28m Average total duration Fastest 2h 28m Onboard + 3h 0m Additional time* | 21h 18m Average total duration 20h 48m Onboard + 30m Additional time* | 3h 13m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greenville, SC to Charleston, SC:
A bus is €185 less than a flight for this route with tickets for a flight from Greenville, SC to Charleston, SC costing on average €298.
A bus is €280 less than a train for this route with tickets for a train from Greenville, SC to Charleston, SC costing on average €394.
Other travel options to Charleston, SC take longer:
Bus takes on average 11h 40m.
Train takes on average 20h 48m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:00AM | Arrival Time 10:30PM | Duration 20h30 | Departure days Tue, Sat | Cheapest price €100 |
Operator Greyhound | Departure Time 03:00AM | Arrival Time 11:30PM | Duration 20h30 | Departure days Tue, Sat | Cheapest price €65 |
Operator Greyhound | Departure Time 03:25AM | Arrival Time 12:45PM | Duration 9h20 | Departure days Tue, Wed, Thu, Sat, Sun | Cheapest price €67 |
Operator Greyhound | Departure Time 07:10AM | Arrival Time 09:40PM | Duration 14h30 | Departure days Wed | Cheapest price €68 |
Operator Greyhound | Departure Time 11:00AM | Arrival Time 09:40PM | Duration 10h40 | Departure days Sat | Cheapest price €67 |
Operator FlixBus | Departure Time 08:20PM | Arrival Time 09:25AM | Duration 13h05 | Departure days Wed, Sat | Cheapest price €68 |
The table below shows live departures for Greenville, SC to Charleston, SC buses for tomorrow, Wednesday, August 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 3:25 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 9h20 | 12:45 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 1 transfer | |
· | 7:10 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 14h30 | 9:40 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Greenville, SC to Charleston, SC run on average 1 times per day, taking around 11h 40m. Cheap bus tickets for this journey start at €62 if you book in advance.
The earliest bus runs at 11:15, the last at 22:00. The fastest bus covers the 201 miles (324 km) distance in 19h 30m.
Distance 201 miles (324 km) |
Average bus duration 11h 40m |
Cheapest ticket price €62 |
Buses per day 1 |
Fastest bus 19h 30m |
First bus 11:15 AM |
Last bus 10:00 PM |
Cheapest Month Nov |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
Find answers to the most common questions about traveling from Greenville, SC to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

Most Greenville, SC to Charleston, SC buses use the Greenville, Woodruff Rd ("Raceway" gas station) to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Greenville, SC and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Greenville, Woodruff Rd ("Raceway" gas station) is 8 km from Greenville city centre. Public transport options include:
Greenville, Woodruff Rd ("Raceway" gas station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Limited dining options available in adjacent areas.
Wi-Fi is available at Greenville, Woodruff Rd ("Raceway" gas station). ATMs are available at Greenville, Woodruff Rd ("Raceway" gas station).
Ticket office support is available at Greenville, Woodruff Rd ("Raceway" gas station).
Available at Greenville, Woodruff Rd ("Raceway" gas station): Parking, Taxis, WC.
Accessibility facilities are available at Greenville, Woodruff Rd ("Raceway" gas station): Basic access available for persons with disabilities.
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
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