- Must visit
Cummer Museum of Art & Gardens
Major art museum with American and European works, a notable sculpture garden, and one of Jacksonville's top cultural stops.
Cheapest price
zł316
Average price
zł330
Fastest journey
10 h 25 m
Average duration
12 h 5 m
Buses per day
4
Distance
507 km
The best way to find a cheap bus ticket from Greenville, SC to Jacksonville, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Jacksonville, FL will cost around zł330 if you buy it on the day, but the cheapest tickets can be found for only zł316.
It's difficult to get from Greenville, SC to Jacksonville, FL without transferring at least once.
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FlixBus · FlixBus · FlixBusOmio recommends booking the bus as it is the most popular option from Greenville, SC to Jacksonville, FL among Omio's users. If you are prioritising price take the bus with prices starting from zł328. For those with little time consider booking a flight which can get you there in 5h 2m. The ticket price range depends on the travel mode: a bus costs an average of zł328, and a flight costs an average of zł553.
Distance: 315 miles (507 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
zł583 Average price Cheapest | zł706 Average price | zł1129 Average price | zł275 Average price (fuel + tolls) |
11h 55m Average total duration 11h 25m Onboard + 30m Additional time* | 23h 59m Average total duration 23h 29m Onboard + 30m Additional time* | 8h 2m Average total duration Fastest 5h 2m Onboard + 3h 0m Additional time* | 5h 33m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greenville, SC to Jacksonville, FL:
A bus is zł123 less than a train for this route with tickets for a train from Greenville, SC to Jacksonville, FL costing on average zł706.
A bus is zł546 less than a flight for this route with tickets for a flight from Greenville, SC to Jacksonville, FL costing on average zł1129.
Other travel options to Jacksonville, FL take longer:
Bus takes on average 11h 25m.
Train takes on average 23h 29m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 07:10AM | Arrival Time 06:25PM | Duration 11h15 | Departure days Everyday | Cheapest price zł266 |
Operator FlixBus | Departure Time 11:00AM | Arrival Time 09:25PM | Duration 10h25 | Departure days Mon, Tue, Wed, Sat | Cheapest price zł268 |
Operator FlixBus | Departure Time 01:20PM | Arrival Time 11:05PM | Duration 9h45 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price zł275 |
Operator FlixBus | Departure Time 08:20PM | Arrival Time 07:00AM | Duration 10h40 | Departure days Everyday | Cheapest price zł270 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 01:35PM | Duration 16h00 | Departure days Everyday | Cheapest price zł277 |
The table below shows live departures for Greenville, SC to Jacksonville, FL buses for today, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
+ FlixBus | 8:20 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 10h40 | 7:00 AM Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 16h00 | 1:35 PM Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St | 2 transfers | |
| Wednesday, August 5 | |||||
+ FlixBus | 7:10 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 11h15 | 6:25 PM Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St | 1 transfer | |
+ FlixBus | 11:00 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 10h25 | 9:25 PM Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Greenville, SC to Jacksonville, FL run on average 4 times per day, taking around 11h 25m. Cheap bus tickets for this journey start at zł328 if you book in advance.
The earliest bus runs at 07:10, the last at 23:15. The fastest bus covers the 315 miles (507 km) distance in 9h 45m.
Distance 315 miles (507 km) |
Average bus duration 11h 25m |
Cheapest ticket price zł328 |
Buses per day 4 |
Fastest bus 9h 45m |
First bus 7:10 AM |
Last bus 11:15 PM |
Cheapest Month Aug |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Oct - Dec |
Best time to book 14 days |
Discover the best of Jacksonville, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Jacksonville, FL trip today.
Major art museum with American and European works, a notable sculpture garden, and one of Jacksonville's top cultural stops.
Regional history museum covering Northeast Florida through engaging exhibits on city growth, culture, and key local events.
Contemporary art museum in the university district, presenting rotating exhibitions and thoughtful programs by living artists.
Lively riverfront district with museums, restaurants nearby, public art, and one of Jacksonville's best skyline strolls.
Scenic promenade across the river from downtown, ideal for walks, bridge views, and sunset photos along the Southbank.
Creative historic neighborhood known for murals, local shops, nightlife, and a walkable mix of old Jacksonville character.
Mayport shrimp are local Atlantic shrimp, prized for their sweet flavor. They are a Jacksonville seafood staple, often served fried, grilled, or in baskets near the coast.
A Low Country boil with shrimp, sausage, corn, and potatoes reflects Northeast Florida’s coastal Southern cooking and is popular at casual local seafood spots.
Fresh local oysters from nearby Florida waters are served raw, baked, or chargrilled. They are a classic Jacksonville choice tied to the region’s seafood culture.
Popular casual seafood restaurant in Mayport, best known for fresh local shrimp, fried seafood platters, and a laid-back dockside feel.
Refined riverfront steakhouse known for prime steaks, seafood, and polished service in an upscale setting on the Southbank.
Established upscale seafood restaurant with an extensive wine list, elegant atmosphere, and strong reputation for fresh fish and fine dining.
Moderate for US beach cities. Hotels vary by season; meals and coffee are typical US prices, and most visitors need a car as transit is limited.
Tip 18-20% at restaurants, more for great service. Taxis usually get 10-15%. Cafes often use tip jars or screens; $1-2 is common.
Find answers to the most common questions about traveling from Greenville, SC to Jacksonville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.

Most Greenville, SC to Jacksonville, FL buses use the Greenville, Woodruff Rd ("Raceway" gas station) to Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St station pair. Use this guide to compare Greenville, SC and Jacksonville, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Greenville, Woodruff Rd ("Raceway" gas station) is 8 km from Greenville city centre. Public transport options include:
Greenville, Woodruff Rd ("Raceway" gas station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Limited dining options available in adjacent areas.
Wi-Fi is available at Greenville, Woodruff Rd ("Raceway" gas station). ATMs are available at Greenville, Woodruff Rd ("Raceway" gas station).
Ticket office support is available at Greenville, Woodruff Rd ("Raceway" gas station).
Available at Greenville, Woodruff Rd ("Raceway" gas station): Parking, Taxis, WC.
Accessibility facilities are available at Greenville, Woodruff Rd ("Raceway" gas station): Basic access available for persons with disabilities.
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St is 1 km from Jacksonville city centre. Public transport options include:
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St. ATMs are available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St.
Ticket office support is available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St.
Available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St: Parking, Taxis, WC.
Accessibility facilities are available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St: Wheelchair accessible entrances.
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