- Must visit
Cummer Museum of Art & Gardens
Major art museum with American and European works, a notable sculpture garden, and one of Jacksonville's top cultural stops.
Cheapest price on Sep 20
CHF59
Average ticket price on Sep 20
CHF61
Fastest journey on Sep 20
9 h 45 m
Average journey duration on Sep 20
12 h 14 m
Buses on Sep 20
5
Distance
507 km
The best way to find a cheap bus ticket from Greenville, SC to Jacksonville, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Jacksonville, FL will cost around CHF61 if you buy it on the day, but the cheapest tickets can be found for only CHF59.
It's difficult to get from Greenville, SC to Jacksonville, FL without transferring at least once.
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FlixBus · FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Greenville, SC to Jacksonville, FL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of CHF99 For those with little time, consider booking a flight, which has an average total journey time of 5h 30m. Average ticket prices depend on the travel mode: a bus costs an average of CHF99, while a train costs an average of CHF545.
Distance: 315 miles (507 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
CHF99 Average price Cheapest | CHF542 Average price | CHF545 Average price | CHF61 Average price (fuel + tolls) |
10h 46m Average total duration 10h 16m Onboard + 30m Additional time* | 5h 30m Average total duration Fastest 3h 30m Onboard + 2h 0m Additional time* | 23h 46m Average total duration 23h 16m Onboard + 30m Additional time* | 5h 33m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greenville, SC to Jacksonville, FL:
A bus is CHF443 less than a flight for this route with tickets for a flight from Greenville, SC to Jacksonville, FL costing on average CHF542.
A bus is CHF446 less than a train for this route with tickets for a train from Greenville, SC to Jacksonville, FL costing on average CHF545.
Other travel options to Jacksonville, FL take longer:
Bus takes on average 10h 16m.
Train takes on average 23h 16m.
Tickets start at around CHF99 compared to roughly CHF61 in fuel and tolls — a saving of about CHF-38.30. The journey takes 10h 16m versus 5h 33m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:25AM | Arrival Time 04:55PM | Duration 13h30 | Departure days Sun | Cheapest price CHF61 |
Operator FlixBus | Departure Time 07:10AM | Arrival Time 06:25PM | Duration 11h15 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price CHF56 |
Operator FlixBus | Departure Time 01:20PM | Arrival Time 11:05PM | Duration 9h45 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price CHF60 |
Operator FlixBus | Departure Time 08:20PM | Arrival Time 07:00AM | Duration 10h40 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price CHF56 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 01:35PM | Duration 16h00 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price CHF58 |
The table below shows live departures for Greenville, SC to Jacksonville, FL buses for today, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+![]() | 7:10 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 11h15 | 6:25 PM Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St | 1 transfer | |
FlixBus · FlixBus | 1:20 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 9h45 | 11:05 PM Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St | 1 transfer | |
FlixBus+![]() | 8:20 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 10h40 | 7:00 AM Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 16h00 | 1:35 PM Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Greenville, SC to Jacksonville, FL run on average 4 times per day, taking around 10h 16m. Cheap bus tickets for this journey start at CHF60 if you book in advance.
The earliest bus runs at 07:10, the last at 23:15. The fastest bus covers the 315 miles (507 km) distance in 8h 55m.
Distance 315 miles (507 km) |
Average bus duration 10h 16m |
Cheapest ticket price CHF60 |
Buses per day 4 |
Fastest bus 8h 55m |
First bus 7:10 AM |
Last bus 11:15 PM |
Cheapest Month Aug |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 14 days |
Discover the best of Jacksonville, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Jacksonville, FL trip today.
Major art museum with American and European works, a notable sculpture garden, and one of Jacksonville's top cultural stops.
Regional history museum covering Northeast Florida through engaging exhibits on city growth, culture, and key local events.
Contemporary art museum in the university district, presenting rotating exhibitions and thoughtful programs by living artists.
Lively riverfront district with museums, restaurants nearby, public art, and one of Jacksonville's best skyline strolls.
Scenic promenade across the river from downtown, ideal for walks, bridge views, and sunset photos along the Southbank.
Creative historic neighborhood known for murals, local shops, nightlife, and a walkable mix of old Jacksonville character.
Mayport shrimp are local Atlantic shrimp, prized for their sweet flavor. They are a Jacksonville seafood staple, often served fried, grilled, or in baskets near the coast.
A Low Country boil with shrimp, sausage, corn, and potatoes reflects Northeast Florida’s coastal Southern cooking and is popular at casual local seafood spots.
Fresh local oysters from nearby Florida waters are served raw, baked, or chargrilled. They are a classic Jacksonville choice tied to the region’s seafood culture.
Popular casual seafood restaurant in Mayport, best known for fresh local shrimp, fried seafood platters, and a laid-back dockside feel.
Refined riverfront steakhouse known for prime steaks, seafood, and polished service in an upscale setting on the Southbank.
Established upscale seafood restaurant with an extensive wine list, elegant atmosphere, and strong reputation for fresh fish and fine dining.
Moderate for US beach cities. Hotels vary by season; meals and coffee are typical US prices, and most visitors need a car as transit is limited.
Tip 18-20% at restaurants, more for great service. Taxis usually get 10-15%. Cafes often use tip jars or screens; $1-2 is common.
Find answers to the most common questions about traveling from Greenville, SC to Jacksonville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.

Most Greenville, SC to Jacksonville, FL buses use the Greenville, Woodruff Rd ("Raceway" gas station) to Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St station pair. Use this guide to compare Greenville, SC and Jacksonville, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Greenville, Woodruff Rd ("Raceway" gas station) is 8 km from Greenville city centre. Public transport options include:
Greenville, Woodruff Rd ("Raceway" gas station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Limited dining options available in adjacent areas.
Wi-Fi is available at Greenville, Woodruff Rd ("Raceway" gas station). ATMs are available at Greenville, Woodruff Rd ("Raceway" gas station).
Ticket office support is available at Greenville, Woodruff Rd ("Raceway" gas station).
Available at Greenville, Woodruff Rd ("Raceway" gas station): Parking, Taxis, WC.
Accessibility facilities are available at Greenville, Woodruff Rd ("Raceway" gas station): Basic access available for persons with disabilities.
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St is 1 km from Jacksonville city centre. Public transport options include:
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St. ATMs are available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St.
Ticket office support is available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St.
Available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St: Parking, Taxis, WC.
Accessibility facilities are available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St: Wheelchair accessible entrances.
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