- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
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The cheapest and fastest buses from Milwaukee, WI to Charleston, SC
Showing times, prices and bookable tickets for Nov 21
- Cheapest price on Nov 21
- $198
- Average ticket price on Nov 21
- $198
- Fastest journey on Nov 21
- 1 d 21 h 25 m
- Average journey duration on Nov 21
- 1 d 21 h 25 m
- Buses on Nov 21
- 1
- Distance
- 1337 km
Cheap tickets
The best way to find a cheap bus ticket from Milwaukee, WI to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milwaukee, WI to Charleston, SC will cost around $198 if you buy it on the day, but the cheapest tickets can be found for only $198.
Fast buses
On Sat, Nov 21, we found 1 buses from Milwaukee, WI to Charleston, SC, including 1 direct services.
On Sat, Nov 21 the direct buses cover the 1337 km distance in an average of 1 d 21 h 25 m but if you time it right, some buses will get you there in just 1 d 21 h 25 m .
On Sat, Nov 21 the slowest buses will take 1 d 21 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1:05 AM 45h25 Milwaukee, WI 10:30 PM Charleston, SC $198 1 One-way 0 transfers
1:05 AM 45h25 Milwaukee, WI 10:30 PM Charleston, SC $198 1 One-way 0 transfers
Journey information
Overview: Bus from Milwaukee, WI to Charleston, SC
USAUSA
Buses from Milwaukee, WI to Charleston, SC run on average 4 times per day, taking around 30h 6m. Cheap bus tickets for this journey start at $81 if you book in advance.
The earliest bus runs at 09:00, the last at 19:55. The fastest bus covers the 830 miles (1337 km) distance in 24h 15m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 830 miles (1337 km) |
Average bus duration 30h 6m |
Cheapest ticket price $81 |
Buses per day 4 |
Fastest bus 24h 15m |
First bus 9:00 AM |
Last bus 7:55 PM |
Cheapest Month Sep |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Oct - Dec |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Frequently asked questions about your Milwaukee, WI to Charleston, SC trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Milwaukee, WI to Charleston, SC.
Cheap bus tickets from Milwaukee, WI to Charleston, SC can start from as little as $81 when you book in advance. The average bus ticket price for Milwaukee, WI to Charleston, SC is $128 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from Milwaukee, WI to Charleston, SC leaves at 9:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Milwaukee, WI to Charleston, SC leaves at 7:55 PM.
There are 4 buses a day from Milwaukee, WI to Charleston, SC which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
Milwaukee, WI to Charleston, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:05AM | Arrival Time 10:30PM | Duration 45h25 | Departure days Mon | Cheapest price $198 |
Live departures
Milwaukee, WI to Charleston, SC bus times
The table below shows live departures for Milwaukee, WI to Charleston, SC buses for tomorrow, Sunday, November 15. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 1:05 AM Milwaukee, WI | 45h25 | 10:30 PM Charleston, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Milwaukee, WI to Charleston, SC buses with Omio?
Greyhound operates all buses services from Milwaukee, WI to Charleston, SC.
Omio is an official ticket reseller for all your travel options from Milwaukee, WI to Charleston, SC.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Milwaukee, WI to Charleston, SC.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Milwaukee, WI to Charleston, SC.
Bus providers: Greyhound from Milwaukee, WI to Charleston, SCYou can travel by bus between Milwaukee, WI to Charleston, SC with Greyhound for as low as $81. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
24h 15m
Cheapest Greyhound Price
$81
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Companies, tickets, and onboard amenities between Milwaukee, WI and Charleston, SC
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from Milwaukee, WI to Charleston, SC, you can count on Greyhound for the best way to get you to Charleston, SC. You can also check all possible bus companies who offer a service between Milwaukee, WI and Charleston, SC and compare the amenities they offer before buying a bus ticket.
Yes, the following accessibility options are available when taking the bus from Milwaukee, WI to Charleston, SC:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Milwaukee, WI to Charleston, SC for bus company Greyhound.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Whether you can cancel your bus ticket from Milwaukee, WI to Charleston, SC depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, there is food available to purchase on board the bus from Milwaukee, WI to Charleston, SC.
Yes, the following luggage options are included when booking a bus ticket from Milwaukee, WI to Charleston, SC:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Milwaukee, WI to Charleston, SC:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Milwaukee, WI to Charleston, SC.
You can reserve your seat on the bus from Milwaukee, WI to Charleston, SC with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Milwaukee, WI to Charleston, SC with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Milwaukee, WI to Charleston, SC with the following bus company: Greyhound.
Complete guide to Charleston, SC
Things to do in Charleston, SC
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
- Must visit
Gibbes Museum of Art
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
- Must visit
International African American Museum
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
- Must visit
The Battery
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
- Must visit
East Battery
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
- Must visit
Charleston City Market
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
- Gluten-free
Perloo
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
- Gluten-free
Shrimp And Grits
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
She-Crab Soup
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Circa 1886 Restaurant
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
The Ordinary
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Magnolias
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
US Dollar ($)
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Average meal costs
- Budget
- $10-18 for fast food or casual lunch.
- Mid-range
- $25-45 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale restaurants.
- Coffee
- $4-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
Plan your visit to Charleston, SC
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Charleston, SC.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Charleston, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like the historic district and popular tourist spots. Beware of overly aggressive street vendors and unofficial taxi services that may overcharge. Additionally, travelers should avoid leaving valuables unattended and be cautious when using ride-sharing apps to ensure the driver matches the booking details. Staying aware of surroundings and using authorized services helps minimize safety risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from Milwaukee, WI to Charleston, SC
Find answers to the most common questions about traveling from Milwaukee, WI to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.
It's helpful to compare your options as there are 3 ways to travel between Milwaukee, WI and Charleston, SC including taking a bus, train, and flight.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Popular bus stations from Milwaukee, WI to Charleston, SC
Most Milwaukee, WI to Charleston, SC buses use the Milwaukee, Intermodal Station to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Milwaukee, WI and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Milwaukee
Arrival bus stations in Charleston
Which Milwaukee, WI station do buses to Charleston, SC leave from?
Buses from Milwaukee, WI to Charleston, SC leave from Milwaukee, Intermodal Station. The station is 0 miles (1 km) from Milwaukee, WI city centre at Milwaukee, 433 W St. Paul Avenue, Milwaukee, WI 53203, USA.
Milwaukee, Intermodal StationMilwaukee, 433 W St. Paul Avenue, Milwaukee, WI 53203, USA
City-centre transport
Getting to Milwaukee, Intermodal Station from Milwaukee city centre
Milwaukee, Intermodal Station is 1 km from Milwaukee city centre. Public transport options include:
Bus57 · 4m · $5 · every ~4 min
Wisconsin Coach Lines · 6m · $4
Milwaukee, Intermodal Station bus station facilities and services
Milwaukee, Intermodal Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Cafe and vending machines available.
Wi-Fi and ATMs
Wi-Fi available in waiting areas. ATMs are aTM machines available inside the station.
Tickets and information
Ticket office support is available at Milwaukee, Intermodal Station.
Parking, taxis and toilets
Available at Milwaukee, Intermodal Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Milwaukee, Intermodal Station: ADA compliant with elevators and ramps.
Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop)Main Terminal, 5300 S Howell Ave, Milwaukee, WI 53207, USA
City-centre transport
Getting to Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop) from Milwaukee city centre
Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop) is 10 km from Milwaukee city centre. Public transport options include:
BusWisconsin Coach Lines · 10m · $6
Gre · 19m · $4 · every ~8 min
Gre · 27m · $4 · every ~8 min
Gre · 29m · $4 · every ~8 min
Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop) bus station facilities and services
Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Food options are available within the airport terminal.
Wi-Fi and ATMs
Wi-Fi is available at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop). ATMs are aTMs are available in the airport terminal.
Tickets and information
Ticket office support is available at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop).
Parking, taxis and toilets
Available at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop): The station is accessible with facilities for disabled passengers.
Which Charleston, SC station do buses from Milwaukee, WI arrive at?
Buses from Milwaukee, WI to Charleston, SC arrive at Charleston, Gaynor Avenue (Greyhound Bus Station). Charleston, Gaynor Avenue (Greyhound Bus Station) is 8 miles (13 km) from Charleston, SC city centre.
Charleston, Gaynor Avenue (Greyhound Bus Station)4565 Gaynor Ave, Charleston, SC 29405, USA
City-centre transport
Getting to Charleston, Gaynor Avenue (Greyhound Bus Station) from Charleston city centre
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Bus10 · 32m · every ~4 min
10 · 41m · every ~4 min
Charleston, Gaynor Avenue (Greyhound Bus Station) bus station facilities and services
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Parking, taxis and toilets
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
Bus stations for Milwaukee, WI to Charleston, SC
Check bus stations information for Milwaukee, WI and Charleston, SC, including where buses depart and arrive on this route.
When departing from Milwaukee, WI , you have various bus station options to start your journey from including Milwaukee, Intermodal Station, Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop) . When arriving in Charleston, SC , you can end your journey in bus stations like Charleston, Gaynor Avenue (Greyhound Bus Station) .Passengers board the bus most frequently from Milwaukee, Intermodal Station, which is located around 0 miles (1 km) away from the city centre, and they get off the bus at Charleston, Gaynor Avenue (Greyhound Bus Station), located 13 away from the city centre.
Most popular bus connections from Milwaukee, WI
More options for your journey from Milwaukee, WI to Charleston, SC
Here are some other resources that might have the information you need
Most popular buses to and from Charleston, SC and Milwaukee, WI
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