- Must visit
The Charleston Museum
Founded in 1773 and often called America’s first museum, it covers Charleston history, decorative arts, and natural history.
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The cheapest and fastest buses from Milwaukee, WI to Charleston, SC
Showing times and prices for Jul 03
Cheapest price
$177
Average price
$207
Fastest journey
1 d 5 h
Average duration
1 d 9 h 58 m
Buses per day
5
Distance
1337 km
Cheap tickets
The best way to find a cheap bus ticket from Milwaukee, WI to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milwaukee, WI to Charleston, SC will cost around $207 if you buy it on the day, but the cheapest tickets can be found for only $177.
Fast buses
It's difficult to get from Milwaukee, WI to Charleston, SC without transferring at least 3 times.
FlixBus+
· +FlixBus3:40 PM40h45Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI9:25 AMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$1771One-way4 transfers- FlixBus+ · +FlixBus3:20 PM41h05Milwaukee, Intermodal Station9:25 AMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$1781One-way4 transfers
- FlixBus+ · +FlixBus11:50 AM29h40Milwaukee, Intermodal Station6:30 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$2101One-way4 transfers
- FlixBus+ · +FlixBus12:10 PM29h20Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI6:30 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$2101One-way4 transfers
- · +FlixBus+3:25 AM29h00Milwaukee, Intermodal Station9:25 AMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$2591One-way3 transfers
- · +FlixBus+3:25 AM29h00Milwaukee, Intermodal Station9:25 AMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$2591One-way3 transfers
- FlixBus+ · +FlixBus12:10 PM29h20Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI6:30 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$2101One-way4 transfers
- FlixBus+ · +FlixBus11:50 AM29h40Milwaukee, Intermodal Station6:30 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$2101One-way4 transfers
- FlixBus+ · +FlixBus3:40 PM40h45Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI9:25 AMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$1771One-way4 transfers
- FlixBus+ · +FlixBus3:20 PM41h05Milwaukee, Intermodal Station9:25 AMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$1781One-way4 transfers
Travel Information
Compare bus, train, and flight for Milwaukee, WI to Charleston, SC
Omio recommends booking the flight as it is the most popular option from Milwaukee, WI to Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from $203. For those with little time consider booking a flight which can get you there in 4h 35m. The ticket price range depends on the travel mode: a bus costs an average of $203, and a train costs an average of $613.
Distance: 830 miles (1337 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$203 Average price Cheapest | $558 Average price | $613 Average price |
45h 55m Average total duration 45h 25m Onboard + 30m Additional time* | 7h 35m Average total duration Fastest 4h 35m Onboard + 3h 0m Additional time* | 37h 18m Average total duration 36h 48m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Milwaukee, WI to Charleston, SC is a bus with an average price of $203 (€168).
This is compared to other travel options from Milwaukee, WI to Charleston, SC:
A bus is $355 (€292) less than a flight for this route with tickets for a flight from Milwaukee, WI to Charleston, SC costing on average $558 (€460).
A bus is $409 (€338) less than a train for this route with tickets for a train from Milwaukee, WI to Charleston, SC costing on average $613 (€506).
The fastest way to travel from Milwaukee, WI to Charleston, SC is by flight with an average journey time of 4h 35m.
Other travel options to Charleston, SC take longer:
Train takes on average 36h 48m.
Bus takes on average 45h 25m.
It's helpful to compare your options as there are 3 ways to travel between Milwaukee, WI and Charleston, SC including taking a bus, train, and flight.
Milwaukee, WI to Charleston, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:25AM | Arrival Time 08:55AM | Duration 28h30 | Departure days Everyday | Cheapest price $127 |
Operator Greyhound | Departure Time 06:30AM | Arrival Time 06:30PM | Duration 35h00 | Departure days Wed | Cheapest price $165 |
Operator Greyhound | Departure Time 09:00AM | Arrival Time 06:30PM | Duration 32h30 | Departure days Thu, Sat | Cheapest price $122 |
Operator Greyhound | Departure Time 09:20AM | Arrival Time 06:30PM | Duration 32h10 | Departure days Thu, Sat | Cheapest price $122 |
Operator Greyhound | Departure Time 11:50AM | Arrival Time 06:30PM | Duration 29h40 | Departure days Mon, Tue, Fri, Sun | Cheapest price $157 |
Operator Greyhound | Departure Time 12:10PM | Arrival Time 06:30PM | Duration 29h20 | Departure days Mon, Tue, Fri, Sun | Cheapest price $155 |
Operator Greyhound | Departure Time 03:20PM | Arrival Time 08:55AM | Duration 40h35 | Departure days Everyday | Cheapest price $123 |
Operator Greyhound | Departure Time 03:40PM | Arrival Time 08:55AM | Duration 40h15 | Departure days Everyday | Cheapest price $124 |
Live departures
Milwaukee, WI to Charleston, SC bus times
The table below shows live departures for Milwaukee, WI to Charleston, SC buses for today, Thursday, July 2. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · +FlixBus+ | 3:25 AM Milwaukee, Intermodal Station | 29h00 | 9:25 AM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
| FlixBus · FlixBus+ | 9:00 AM Milwaukee, Intermodal Station | 32h30 | 6:30 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 2 transfers | |
| FlixBus · FlixBus+ | 9:20 AM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI | 32h10 | 6:30 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 2 transfers | |
| FlixBus+ · +FlixBus | 3:20 PM Milwaukee, Intermodal Station | 41h05 | 9:25 AM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 4 transfers | |
| FlixBus+ · +FlixBus | 3:40 PM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI | 40h45 | 9:25 AM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 4 transfers |
Find all the dates and times for this journey
Compare prices and tickets Milwaukee, WI to Charleston, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Milwaukee, WI to Charleston, SC
USAUSA
Buses from Milwaukee, WI to Charleston, SC run on average 4 times per day, taking around 45h 25m. Cheap bus tickets for this journey start at $203 (€168) if you book in advance.
The earliest bus runs at 09:00, the last at 19:55. The fastest bus covers the 830 miles (1337 km) distance in 45h 25m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 830 miles (1337 km) |
Average bus duration 45h 25m |
Cheapest ticket price $203 (€168) |
Buses per day 4 |
Fastest bus 45h 25m |
First bus 9:00 AM |
Last bus 7:55 PM |
Cheapest Month Nov |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Oct - Dec |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Complete guide to Charleston
Things to do in Charleston
Discover the best of Charleston — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston trip today.
- Must visit
Gibbes Museum of Art
Charleston’s leading art museum, known for American art with a strong focus on Southern artists and a polished historic setting.
- Must visit
International African American Museum
A major modern museum at Gadsden’s Wharf exploring African American history, culture, and the transatlantic journey.
- Must visit
The Battery
Charleston’s classic waterfront promenade, loved for harbor breezes, historic mansions, and postcard-worthy walking views.
- Must visit
Waterfront Park
A highly popular riverfront park with piers, swings, and the famous Pineapple Fountain, especially popular for photos.
- Must visit
King Street
The city’s best-known shopping and strolling corridor, mixing historic streetscape, boutiques, galleries, and nightlife energy.
- Gluten-free
Shrimp And Grits
A Lowcountry classic of sautéed shrimp served over creamy grits, often with bacon or gravy. It is one of Charleston’s signature dishes and widely associated with the city’s food culture.
- Gluten-free
She-Crab Soup
A rich, creamy crab soup traditionally finished with crab roe and a splash of sherry. It is a historic Charleston specialty found in many classic local restaurants.
Oyster Roast
Fresh local oysters roasted in the shell and served communally, usually with crackers and hot sauce. Oyster roasts are a beloved Charleston and Lowcountry social food tradition.
FIG
An established fine-dining favorite focused on seasonal Southern cooking and local produce. It is widely respected for elegant plates and a warm, understated atmosphere.
Husk
A well-known Charleston restaurant celebrating Southern ingredients with a refined menu and historic setting. Known for polished service and creative takes on regional classics.
Fleet Landing Restaurant & Bar
A popular waterfront venue in a historic naval building, known for seafood, Lowcountry staples, and harbor views. It offers a lively but approachable atmosphere.
United States Dollar
Charleston is moderate to expensive by U.S. standards. Hotels and fine dining can be pricey, but casual food and coffee are manageable.
Average meal costs
- Budget
- USD 10-18 for casual spots or takeaway.
- Mid-range
- USD 25-45 per person at a mid-range restaurant.
- Fine dining
- USD 75+ per person at upscale restaurants.
- Coffee
- USD 4-7 for a coffee drink.
Tipping culture
Tip 18-20% in restaurants; 20%+ for great service. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and valet.
FAQs: Bus from Milwaukee, WI to Charleston, SC
Find answers to the most common questions about traveling from Milwaukee, WI to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Milwaukee, WI to Charleston, SC can start from as little as $203 (€168) when you book in advance. The average bus ticket price for Milwaukee, WI to Charleston, SC is $203 (€168) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Milwaukee, WI to Charleston, SC is 45h 25m to travel the 830 miles (1337 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Milwaukee, WI to Charleston, SC leaves at 9:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Milwaukee, WI to Charleston, SC leaves at 7:55 PM.
A trip to Charleston, SC from Milwaukee, WI is worth doing but not as a day trip with a journey time of 45h 25m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Milwaukee, WI to Charleston, SC is November.
It's helpful to compare your options as there are 3 ways to travel between Milwaukee, WI and Charleston, SC including taking a bus, train, and flight.
No, the bus from Milwaukee, WI to Charleston, SC has no accessibility options.
No, there are no bathrooms on board the bus from Milwaukee, WI to Charleston, SC.
No, bikes are not allowed on board the bus from Milwaukee, WI to Charleston, SC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Milwaukee, WI to Charleston, SC.
No, luggage for the bus from Milwaukee, WI to Charleston, SC needs to be booked in addition.
No, there are no additional luggage options for the bus from Milwaukee, WI to Charleston, SC.
Unfortunately, pets are not allowed on the bus from Milwaukee, WI to Charleston, SC.
No, there are no USB plugs on board the bus from Milwaukee, WI to Charleston, SC.
No, there is no WiFi on board the bus from Milwaukee, WI to Charleston, SC.
Since neither Milwaukee, WI nor Charleston, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Charleston, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like the historic district and popular tourist spots. Beware of overly aggressive street vendors and unofficial taxi services that may overcharge. Additionally, travelers should avoid leaving valuables unattended and be cautious when using ride-sharing apps to ensure the driver matches the booking details. Staying aware of surroundings and using authorized services helps minimize safety risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Milwaukee, WI to Charleston, SC
Most Milwaukee, WI to Charleston, SC buses use the Milwaukee, Intermodal Station to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Milwaukee, WI and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Milwaukee
Arrival bus stations in Charleston
Milwaukee, Intermodal Station
City-centre transport
Getting to Milwaukee, Intermodal Station from Milwaukee city centre
Bus57 · 4m · $5 · every ~4 min
Wisconsin Coach Lines · 6m · $4
Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop)
City-centre transport
Getting to Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop) from Milwaukee city centre
BusWisconsin Coach Lines · 10m · $6
Gre · 19m · $4 · every ~8 min
Gre · 27m · $4 · every ~8 min
Gre · 29m · $4 · every ~8 min
Charleston, Gaynor Avenue (Greyhound Bus Station)
City-centre transport
Getting to Charleston, Gaynor Avenue (Greyhound Bus Station) from Charleston city centre
Bus10 · 32m · every ~4 min
10 · 41m · every ~4 min
Most popular bus connections from Milwaukee, WI
More options for your journey from Milwaukee, WI to Charleston, SC
Here are some other resources that might have the information you need
Most popular buses to and from Charleston, SC and Milwaukee, WI
Most popular bus connections to Charleston, SC
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