The cheapest and fastest buses from Milwaukee, WI to Charleston, SC
Cheapest price
$148
Average price
$148
Fastest journey
1 d 8 h 10 m
Average duration
1 d 8 h 10 m
Buses per day
1
Distance
1337 km
The best way to find a cheap bus ticket from Milwaukee, WI to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milwaukee, WI to Charleston, SC will cost around $148 if you buy it on the day, but the cheapest tickets can be found for only $148.
Of the 1 buses that leave Milwaukee, WI for Charleston, SC on Tue, Mar 24, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Mar 24 the direct buses cover the 1337 km distance in an average of 1 d 8 h 10 m but if you time it right, some buses will get you there in just 1 d 8 h 10 m .
On Tue, Mar 24 the slowest buses will take 1 d 8 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for Milwaukee, WI to Charleston, SC
Omio recommends booking the train as it is the most popular option from Milwaukee, WI to Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from $148. For those with little time consider booking a flight which can get you there in 6h 24m. The ticket price range depends on the travel mode: a bus costs an average of $148, and a train costs an average of $337.
Distance: 830 miles (1337 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$213 Average price Cheapest | $502 Average price | $394 Average price |
39h 43m Average total duration 39h 13m Onboard + 30m Additional time* | 37h 18m Average total duration 36h 48m Onboard + 30m Additional time* | 9h 24m Average total duration Fastest 6h 24m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Milwaukee, WI to Charleston, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Mar 29
Mar 30
Why should you book Milwaukee, WI to Charleston, SC buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Milwaukee, WI to Charleston, SC.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Milwaukee, WI to Charleston, SC.
Journey information
Overview: Bus from Milwaukee, WI to Charleston, SC
Buses from Milwaukee, WI to Charleston, SC run on average 4 times per day, taking around 39h 13m. Cheap bus tickets for this journey start at $148 (€120) if you book in advance.
The earliest bus runs at 11:15, the last at 15:15. The fastest bus covers the 830 miles (1337 km) distance in 32h 10m.
Distance 830 miles (1337 km) |
Average bus duration 39h 13m |
Cheapest ticket price $148 (€120) |
Buses per day 4 |
Fastest bus 32h 10m |
First bus 11:15 |
Last bus 15:15 |
Bus providers: Greyhound from Milwaukee, WI to Charleston, SCYou can travel by bus between Milwaukee, WI to Charleston, SC with Greyhound for as low as $148 (€120). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Milwaukee, WI to Charleston, SC
Find answers to the most common questions about traveling from Milwaukee, WI to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Milwaukee, WI to Charleston, SC
Most popular bus connections from Milwaukee, WI
More options for your journey from Milwaukee, WI to Charleston, SC
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