The cheapest and fastest buses from Milwaukee, WI to Charleston, SC
Cheapest price
$466
Average price
$466
Fastest journey
1 d 8 h 5 m
Average duration
1 d 8 h 5 m
Buses per day
1
Distance
1337 km
The best way to find a cheap bus ticket from Milwaukee, WI to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milwaukee, WI to Charleston, SC will cost around $466 if you buy it on the day, but the cheapest tickets can be found for only $466.
It's difficult to get from Milwaukee, WI to Charleston, SC without transferring at least 3 times.


Travel Information
Compare bus for Milwaukee, WI to Charleston, SC
Omio recommends booking the flight as it is the most popular option from Milwaukee, WI to Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from €120. For those with little time consider booking a flight which can get you there in 6h 24m. The ticket price range depends on the travel mode: a bus costs an average of €120, and a train costs an average of €274.
Distance: 830 miles (1337 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€173 Average price Cheapest | €320 Average price | €408 Average price |
39h 43m Average total duration 39h 13m Onboard + 30m Additional time* | 9h 24m Average total duration Fastest 6h 24m Onboard + 3h 0m Additional time* | 37h 18m Average total duration 36h 48m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Milwaukee, WI to Charleston, SC bus times
The table below shows live departures for Milwaukee, WI to Charleston, SC buses for tomorrow, Friday, February 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:55 AM Milwaukee, WI | 32h05 | 7:00 PM Charleston, SC | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milwaukee, WI to Charleston, SC by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 06
Feb 07
Feb 08
Feb 09
Feb 10
Feb 11
Feb 12
Why should you book Milwaukee, WI to Charleston, SC buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of to find the best option for your trip from Milwaukee, WI to Charleston, SC.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Wanderu?
Journey information
Overview: Bus from Milwaukee, WI to Charleston, SC
Buses from Milwaukee, WI to Charleston, SC run on average 4 times per day, taking around 39h 13m. Cheap bus tickets for this journey start at $151 (€120) if you book in advance.
The earliest bus runs at 11:15, the last at 15:15. The fastest bus covers the 830 miles (1337 km) distance in 32h 10m.
Distance 830 miles (1337 km) |
Average bus duration 39h 13m |
Cheapest ticket price $151 (€120) |
Buses per day 4 |
Fastest bus 32h 10m |
First bus 11:15 |
Last bus 15:15 |
Bus providers: Greyhound from Milwaukee, WI to Charleston, SCYou can travel by bus between Milwaukee, WI to Charleston, SC with Greyhound for as low as $151 (€120). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Milwaukee, WI to Charleston, SC
Find answers to the most common questions about traveling from Milwaukee, WI to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Milwaukee, WI to Charleston, SC
Most popular bus connections from Milwaukee, WI
More options for your journey from Milwaukee, WI to Charleston, SC
Here are some other resources that might have the information you need
