- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
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The cheapest and fastest buses from Milwaukee, WI to Charleston, SC
Showing times and prices for Aug 17
Cheapest price
$173
Average price
$173
Fastest journey
1 d 8 h 10 m
Average duration
1 d 8 h 20 m
Buses per day
2
Distance
1337 km
Cheap tickets
The best way to find a cheap bus ticket from Milwaukee, WI to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milwaukee, WI to Charleston, SC will cost around $173 if you buy it on the day, but the cheapest tickets can be found for only $173.
Fast buses
It's difficult to get from Milwaukee, WI to Charleston, SC without transferring at least 2 times.
FlixBus · FlixBus+
9:00 AM32h30Milwaukee, Intermodal Station6:30 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$1731One-way2 transfers- FlixBus · FlixBus+9:20 AM32h10Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI6:30 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$1731One-way2 transfers
- FlixBus · FlixBus+9:20 AM32h10Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI6:30 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$1731One-way2 transfers
- FlixBus · FlixBus+9:00 AM32h30Milwaukee, Intermodal Station6:30 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$1731One-way2 transfers
Travel Information
Compare bus, train, and flight for Milwaukee, WI to Charleston, SC
Omio recommends booking the flight as it is the most popular option from Milwaukee, WI to Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from $207. For those with little time consider booking a flight which can get you there in 4h 35m. The ticket price range depends on the travel mode: a bus costs an average of $207, and a train costs an average of $623.
Distance: 830 miles (1337 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$207 Average price Cheapest | $567 Average price | $623 Average price |
45h 55m Average total duration 45h 25m Onboard + 30m Additional time* | 7h 35m Average total duration Fastest 4h 35m Onboard + 3h 0m Additional time* | 37h 18m Average total duration 36h 48m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Milwaukee, WI to Charleston, SC is a bus with an average price of $207.
This is compared to other travel options from Milwaukee, WI to Charleston, SC:
A bus is $360 less than a flight for this route with tickets for a flight from Milwaukee, WI to Charleston, SC costing on average $567.
A bus is $416 less than a train for this route with tickets for a train from Milwaukee, WI to Charleston, SC costing on average $623.
The fastest way to travel from Milwaukee, WI to Charleston, SC is by flight with an average journey time of 4h 35m.
Other travel options to Charleston, SC take longer:
Train takes on average 36h 48m.
Bus takes on average 45h 25m.
It's helpful to compare your options as there are 3 ways to travel between Milwaukee, WI and Charleston, SC including taking a bus, train, and flight.
Milwaukee, WI to Charleston, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:25AM | Arrival Time 09:10AM | Duration 28h45 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $116 |
Operator Greyhound | Departure Time 06:30AM | Arrival Time 06:30PM | Duration 35h00 | Departure days Wed | Cheapest price $169 |
Operator Greyhound | Departure Time 09:00AM | Arrival Time 06:30PM | Duration 32h30 | Departure days Mon, Tue, Thu, Sun | Cheapest price $114 |
Operator Greyhound | Departure Time 09:20AM | Arrival Time 06:30PM | Duration 32h10 | Departure days Mon, Tue, Thu, Sun | Cheapest price $114 |
Operator Greyhound | Departure Time 11:50AM | Arrival Time 06:30PM | Duration 29h40 | Departure days Fri, Sat | Cheapest price $118 |
Operator Greyhound | Departure Time 12:10PM | Arrival Time 06:30PM | Duration 29h20 | Departure days Fri, Sat | Cheapest price $118 |
Operator Greyhound | Departure Time 03:20PM | Arrival Time 09:10AM | Duration 40h50 | Departure days Tue, Sun | Cheapest price $147 |
Operator Greyhound | Departure Time 03:40PM | Arrival Time 09:25AM | Duration 40h45 | Departure days Tue, Thu, Fri, Sat, Sun | Cheapest price $118 |
Live departures
Milwaukee, WI to Charleston, SC bus times
The table below shows live departures for Milwaukee, WI to Charleston, SC buses for today, Sunday, August 16. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · +FlixBus+ | 3:25 AM Milwaukee, Intermodal Station | 28h45 | 9:10 AM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
| FlixBus · FlixBus+ | 9:00 AM Milwaukee, Intermodal Station | 32h30 | 6:30 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 2 transfers | |
| FlixBus · FlixBus+ | 9:20 AM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI | 32h10 | 6:30 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 2 transfers | |
| FlixBus+ · +FlixBus | 3:20 PM Milwaukee, Intermodal Station | 40h50 | 9:10 AM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 4 transfers | |
| FlixBus+ · +FlixBus | 3:40 PM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI | 40h30 | 9:10 AM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 4 transfers |
Find all the dates and times for this journey
Compare prices and tickets Milwaukee, WI to Charleston, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Milwaukee, WI to Charleston, SC
USAUSA
Buses from Milwaukee, WI to Charleston, SC run on average 4 times per day, taking around 45h 25m. Cheap bus tickets for this journey start at $207 if you book in advance.
The earliest bus runs at 09:00, the last at 19:55. The fastest bus covers the 830 miles (1337 km) distance in 45h 25m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 830 miles (1337 km) |
Average bus duration 45h 25m |
Cheapest ticket price $207 |
Buses per day 4 |
Fastest bus 45h 25m |
First bus 9:00 AM |
Last bus 7:55 PM |
Cheapest Month Nov |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Oct - Dec |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Complete guide to Charleston, SC
Things to do in Charleston, SC
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
- Must visit
Gibbes Museum of Art
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
- Must visit
International African American Museum
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
- Must visit
The Battery
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
- Must visit
East Battery
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
- Must visit
Charleston City Market
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
- Gluten-free
Perloo
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
- Gluten-free
Shrimp And Grits
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
She-Crab Soup
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Circa 1886 Restaurant
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
The Ordinary
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Magnolias
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
US Dollar ($)
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Average meal costs
- Budget
- $10-18 for fast food or casual lunch.
- Mid-range
- $25-45 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale restaurants.
- Coffee
- $4-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
FAQs: Bus from Milwaukee, WI to Charleston, SC
Find answers to the most common questions about traveling from Milwaukee, WI to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Milwaukee, WI to Charleston, SC can start from as little as $207 when you book in advance. The average bus ticket price for Milwaukee, WI to Charleston, SC is $207 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Milwaukee, WI to Charleston, SC is 45h 25m to travel the 830 miles (1337 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Milwaukee, WI to Charleston, SC leaves at 9:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Milwaukee, WI to Charleston, SC leaves at 7:55 PM.
When departing from Milwaukee, WI , you have various bus station options to start your journey from including Milwaukee, Intermodal Station, Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI . When arriving in Charleston, SC , you can end your journey in bus stations like Charleston, Gaynor Avenue (Greyhound Bus Station), SC .Passengers board the bus most frequently from Milwaukee, Intermodal Station, which is located around 0 miles (1 km) away from the city centre, and they get off the bus at Charleston, Gaynor Avenue (Greyhound Bus Station), SC, located 12 away from the city centre.
A trip to Charleston, SC from Milwaukee, WI is worth doing but not as a day trip with a journey time of 45h 25m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Milwaukee, WI to Charleston, SC is November.
It's helpful to compare your options as there are 3 ways to travel between Milwaukee, WI and Charleston, SC including taking a bus, train, and flight.
No, the bus from Milwaukee, WI to Charleston, SC has no accessibility options.
No, there are no bathrooms on board the bus from Milwaukee, WI to Charleston, SC.
No, bikes are not allowed on board the bus from Milwaukee, WI to Charleston, SC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Milwaukee, WI to Charleston, SC.
No, luggage for the bus from Milwaukee, WI to Charleston, SC needs to be booked in addition.
No, there are no additional luggage options for the bus from Milwaukee, WI to Charleston, SC.
Unfortunately, pets are not allowed on the bus from Milwaukee, WI to Charleston, SC.
No, there are no USB plugs on board the bus from Milwaukee, WI to Charleston, SC.
No, there is no WiFi on board the bus from Milwaukee, WI to Charleston, SC.
Since neither Milwaukee, WI nor Charleston, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Charleston, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like the historic district and popular tourist spots. Beware of overly aggressive street vendors and unofficial taxi services that may overcharge. Additionally, travelers should avoid leaving valuables unattended and be cautious when using ride-sharing apps to ensure the driver matches the booking details. Staying aware of surroundings and using authorized services helps minimize safety risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Milwaukee, WI to Charleston, SC
Most Milwaukee, WI to Charleston, SC buses use the Milwaukee, Intermodal Station to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Milwaukee, WI and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Milwaukee
Arrival bus stations in Charleston
Which Milwaukee, WI station do buses to Charleston, SC leave from?
Buses from Milwaukee, WI to Charleston, SC leave from Milwaukee, Intermodal Station. The station is 0 miles (1 km) from Milwaukee, WI city centre at Milwaukee, 433 W St. Paul Avenue, Milwaukee, WI 53203, USA.
Milwaukee, Intermodal StationMilwaukee, 433 W St. Paul Avenue, Milwaukee, WI 53203, USA
City-centre transport
Getting to Milwaukee, Intermodal Station from Milwaukee city centre
Milwaukee, Intermodal Station is 1 km from Milwaukee city centre. Public transport options include:
Bus57 · 4m · $5 · every ~4 min
Wisconsin Coach Lines · 6m · $4
Milwaukee, Intermodal Station bus station facilities and services
Milwaukee, Intermodal Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Cafe and vending machines available.
Wi-Fi and ATMs
Wi-Fi available in waiting areas. ATMs are aTM machines available inside the station.
Tickets and information
Ticket office support is available at Milwaukee, Intermodal Station.
Parking, taxis and toilets
Available at Milwaukee, Intermodal Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Milwaukee, Intermodal Station: ADA compliant with elevators and ramps.
Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop)Main Terminal, 5300 S Howell Ave, Milwaukee, WI 53207, USA
City-centre transport
Getting to Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop) from Milwaukee city centre
Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop) is 10 km from Milwaukee city centre. Public transport options include:
BusWisconsin Coach Lines · 10m · $6
Gre · 19m · $4 · every ~8 min
Gre · 27m · $4 · every ~8 min
Gre · 29m · $4 · every ~8 min
Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop) bus station facilities and services
Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Food options are available within the airport terminal.
Wi-Fi and ATMs
Wi-Fi is available at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop). ATMs are aTMs are available in the airport terminal.
Tickets and information
Ticket office support is available at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop).
Parking, taxis and toilets
Available at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop): The station is accessible with facilities for disabled passengers.
Which Charleston, SC station do buses from Milwaukee, WI arrive at?
Buses from Milwaukee, WI to Charleston, SC arrive at Charleston, Gaynor Avenue (Greyhound Bus Station). Charleston, Gaynor Avenue (Greyhound Bus Station) is 8 miles (13 km) from Charleston, SC city centre.
Charleston, Gaynor Avenue (Greyhound Bus Station)4565 Gaynor Ave, Charleston, SC 29405, USA
City-centre transport
Getting to Charleston, Gaynor Avenue (Greyhound Bus Station) from Charleston city centre
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Bus10 · 32m · every ~4 min
10 · 41m · every ~4 min
Charleston, Gaynor Avenue (Greyhound Bus Station) bus station facilities and services
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Parking, taxis and toilets
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
Most popular bus connections from Milwaukee, WI
More options for your journey from Milwaukee, WI to Charleston, SC
Here are some other resources that might have the information you need
Most popular buses to and from Charleston, SC and Milwaukee, WI
Most popular bus connections to Charleston, SC
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