Travel Information
Compare bus, train, and flight for Greenville, SC to Detroit, MI
Omio recommends booking the bus as it is the most popular option from Greenville, SC to Detroit, MI among Omio's users. If you are prioritising price take the bus with prices starting from $118. For those with little time consider booking a flight which can get you there in 7h 14m. The ticket price range depends on the travel mode: a bus costs an average of $118, and a flight costs an average of $315.
Distance: 518 miles (834 km)
Compare bus with
Most popular Bus | Flight | Train |
|---|---|---|
$127 Average price Cheapest | $330 Average price | $244 Average price |
19h 46m Average total duration 19h 16m Onboard + 30m Additional time* | 10h 14m Average total duration Fastest 7h 14m Onboard + 3h 0m Additional time* | 29h 42m Average total duration 29h 12m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Greenville, SC to Detroit, MI by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Greenville, SC to Detroit, MI buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Greenville, SC to Detroit, MI.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Greenville, SC to Detroit, MI.
Journey information
Overview: Bus from Greenville, SC to Detroit, MI
Buses from Greenville, SC to Detroit, MI run on average 3 times per day, taking around 19h 16m. Cheap bus tickets for this journey start at $118 (€96) if you book in advance.
The earliest bus runs at 02:23, the last at 23:55. The fastest bus covers the 518 miles (834 km) distance in 19h 45m.
Distance 518 miles (834 km) |
Average bus duration 19h 16m |
Cheapest ticket price $118 (€96) |
Buses per day 3 |
Fastest bus 19h 45m |
First bus 02:23 |
Last bus 23:55 |
Bus providers: Greyhound from Greenville, SC to Detroit, MIYou can travel by bus between Greenville, SC to Detroit, MI with Greyhound for as low as $118 (€96). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Greenville, SC to Detroit, MI
Find answers to the most common questions about traveling from Greenville, SC to Detroit, MI by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Detroit, MI, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Detroit Institute of Arts, a renowned museum housing over 65,000 artworks from various cultures and eras
- The Henry Ford, a sprawling complex dedicated to American innovation and history, featuring the Henry Ford Museum and Greenfield Village
- Detroit Riverwalk, a scenic promenade along the Detroit River offering views, parks, and recreational activities
- Belle Isle Park, a 982-acre island park with attractions like an aquarium, conservatory, and nature trails
- Guardian Building, an iconic skyscraper known for its stunning Art Deco architecture and vibrant interior design.
- Motown Museum, the iconic birthplace of the Motown Sound offering guided tours of the historic recording studios
- Eastern Market, a vibrant public market offering fresh produce, local goods, and a lively atmosphere with events and street art
- Detroit Historical Museum, showcasing the rich history of Detroit through engaging exhibits and interactive displays
- Detroit Zoo, featuring a wide variety of animals and immersive habitats
- Comerica Park, a baseball stadium offering games, tours, and family-friendly activities.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Greenville, SC to Detroit, MI
Most popular bus connections from Greenville, SC
More options for your journey from Greenville, SC to Detroit, MI
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