- Must visit
Detroit Institute of Arts
World-class museum with Diego Rivera’s Detroit Industry murals and major collections spanning ancient to contemporary art.
The best way to find a cheap bus ticket from Greenville, SC to Detroit, MI is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Detroit, MI will cost around €109 if you buy it on the day, but the cheapest tickets can be found for only €109.
On Thu, Nov 05, we found 1 buses from Greenville, SC to Detroit, MI, including 1 direct services.
On Thu, Nov 05 the direct buses cover the 834 km distance in an average of 19 h 45 m but if you time it right, some buses will get you there in just 19 h 45 m .
On Thu, Nov 05 the slowest buses will take 19 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Greenville, SC to Detroit, MI run on average 2 times per day, taking around 17h 51m. Cheap bus tickets for this journey start at €64 if you book in advance.
The earliest bus runs at 02:23, the last at 23:55. The fastest bus covers the 518 miles (834 km) distance in 16h 45m.
Distance 518 miles (834 km) |
Average bus duration 17h 51m |
Cheapest ticket price €64 |
Buses per day 2 |
Fastest bus 16h 45m |
First bus 2:23 AM |
Last bus 11:55 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Oct - Dec |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Greenville, SC to Detroit, MI.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:00AM | Arrival Time 09:45PM | Duration 19h45 | Departure days Thu | Cheapest price €109 |
Operator Greyhound | Departure Time 02:45PM | Arrival Time 09:55AM | Duration 19h10 | Departure days Tue, Fri, Sun | Cheapest price €70 |
Operator Greyhound | Departure Time 07:45PM | Arrival Time 02:55PM | Duration 19h10 | Departure days Sat | Cheapest price €122 |
Operator Greyhound | Departure Time 09:35PM | Arrival Time 06:00PM | Duration 20h25 | Departure days Tue, Fri, Sun | Cheapest price €72 |
The table below shows live departures for Greenville, SC to Detroit, MI buses for today, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 2:45 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 19h10 | 9:55 AM Detroit, Greyhound Terminal | 1 transfer | |
| Wednesday, November 4 | |||||
![]() | 2:00 AM Greenville, SC | 19h45 | 9:45 PM Detroit, MI | 0 transfersDirect | |
| Tuesday, November 3 | |||||
FlixBus+![]() | 9:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 20h25 | 6:00 PM Detroit, Greyhound Terminal | 1 transfer | |
This is the last bus of the day. | |||||
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Discover the best of Detroit, MI — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Detroit, MI trip today.
World-class museum with Diego Rivera’s Detroit Industry murals and major collections spanning ancient to contemporary art.
Immersive museum of African American history, culture, and achievement with strong regional and national storytelling.
Motown’s original Studio A preserves the sound and stories behind legendary recordings that shaped popular music worldwide.
Riverfront promenade with public art, plazas, and skyline views; one of the city’s best places for a scenic walk.
Large island park with gardens, trails, beaches, and major attractions, offering a nature escape minutes from downtown.
Revived public square at the city center, hosting events, seasonal programming, and easy access to downtown landmarks.
A square deep-dish pizza with a crisp, caramelized cheese edge and striped sauce. It is Detroit’s signature pie, born in blue steel auto pans.
A hot dog topped with chili, mustard, and diced onions on a steamed bun. It is a classic Detroit street food tied to Greek-American diners.
A layered sandwich of corned beef, swiss cheese, coleslaw, and Russian dressing on grilled rye. It is a beloved deli staple in metro Detroit.
Acclaimed fine-dining restaurant focused on seasonal tasting menus and polished service. One of Detroit’s top special-occasion destinations.
Beloved Eastern Market bakery known for paczki, cakes, and old-school sweets. Expect a busy, nostalgic counter-service experience.
Historic downtown institution famous for Detroit-style square pizza in a lively, casual setting with old-school local character.
Moderate for US city breaks: hotels and dining are mid-priced, transit is limited, and car or rideshare costs can raise daily spend.
Tip 18-20% in restaurants, $1-2 per drink at bars, 10-15% for taxis, and spare change or about 10% in cafes if there is table service.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Detroit, MI.
Find answers to the most common questions about traveling from Greenville, SC to Detroit, MI by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Detroit, MI, this guide helps you travel smarter and with confidence.

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