Journey information
Overview: Bus from Greenville, SC to Detroit, MI
Take a bus from Greenville, SC to Detroit, MI and enjoy the approximately 518 miles (834 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 02:23, the last at 23:55.
Distance 518 miles (834 km) |
Average bus duration 19h 16m |
Buses per day 3 |
First bus 02:23 |
Last bus 23:55 |
Bus providers: Greyhound from Greenville, SC to Detroit, MIYou can travel by bus between Greenville, SC to Detroit, MI with Greyhound. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Greenville, SC to Detroit, MI
Find answers to the most common questions about traveling from Greenville, SC to Detroit, MI by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Detroit, MI, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Detroit Institute of Arts, a renowned museum housing over 65,000 artworks from various cultures and eras
- The Henry Ford, a sprawling complex dedicated to American innovation and history, featuring the Henry Ford Museum and Greenfield Village
- Detroit Riverwalk, a scenic promenade along the Detroit River offering views, parks, and recreational activities
- Belle Isle Park, a 982-acre island park with attractions like an aquarium, conservatory, and nature trails
- Guardian Building, an iconic skyscraper known for its stunning Art Deco architecture and vibrant interior design.
- Motown Museum, the iconic birthplace of the Motown Sound offering guided tours of the historic recording studios
- Eastern Market, a vibrant public market offering fresh produce, local goods, and a lively atmosphere with events and street art
- Detroit Historical Museum, showcasing the rich history of Detroit through engaging exhibits and interactive displays
- Detroit Zoo, featuring a wide variety of animals and immersive habitats
- Comerica Park, a baseball stadium offering games, tours, and family-friendly activities.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Greenville, SC to Detroit, MI, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Greenville, SC to Detroit, MI
Most popular bus connections from Greenville, SC
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