- Must visit
Detroit Institute of Arts
Major fine arts museum known for its encyclopedic collection and Diego Rivera’s Detroit Industry Murals.
Cheapest price
$148
Average price
$148
Fastest journey
19 h 10 m
Average duration
19 h 10 m
Buses per day
1
Distance
834 km
The best way to find a cheap bus ticket from Greenville, SC to Detroit, MI is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Detroit, MI will cost around $148 if you buy it on the day, but the cheapest tickets can be found for only $148.
Of the 1 buses that leave Greenville, SC for Detroit, MI on Sat, Jun 20, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 20 the direct buses cover the 834 km distance in an average of 19 h 10 m but if you time it right, some buses will get you there in just 19 h 10 m .
On Sat, Jun 20 the slowest buses will take 19 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Greenville, SC to Detroit, MI among Omio's users. If you are prioritising price take the bus with prices starting from $133. For those with little time consider booking a flight which can get you there in 6h 27m. The ticket price range depends on the travel mode: a bus costs an average of $133, and a flight costs an average of $517.
Distance: 518 miles (834 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$158 Average price Cheapest | $564 Average price | $456 Average price | $132 Average price (fuel + tolls) |
19h 46m Average total duration 19h 16m Onboard + 30m Additional time* | 9h 27m Average total duration Fastest 6h 27m Onboard + 3h 0m Additional time* | 41h 27m Average total duration 40h 57m Onboard + 30m Additional time* | 10h 28m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greenville, SC to Detroit, MI:
A bus is $298 (€244) less than a train for this route with tickets for a train from Greenville, SC to Detroit, MI costing on average $456 (€374).
A bus is $406 (€332) less than a flight for this route with tickets for a flight from Greenville, SC to Detroit, MI costing on average $564 (€462).
Other travel options to Detroit, MI take longer:
Bus takes on average 19h 16m.
Train takes on average 40h 57m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:45PM | Arrival Time 09:55AM | Duration 19h10 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $106 |
Operator Greyhound | Departure Time 05:45PM | Arrival Time 05:10PM | Duration 23h25 | Departure days Mon | Cheapest price $128 |
Operator Greyhound | Departure Time 07:45PM | Arrival Time 02:55PM | Duration 19h10 | Departure days Sat | Cheapest price $148 |
Operator Greyhound | Departure Time 09:35PM | Arrival Time 06:00PM | Duration 20h25 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $104 |
The table below shows live departures for Greenville, SC to Detroit, MI buses for today, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 2:45 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 19h10 | 9:55 AM Detroit, Greyhound Terminal | 1 transfer | |
FlixBus+![]() | 9:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 20h25 | 6:00 PM Detroit, Greyhound Terminal | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Greenville, SC to Detroit, MI run on average 3 times per day, taking around 19h 16m. Cheap bus tickets for this journey start at $133 (€109) if you book in advance.
The earliest bus runs at 02:23, the last at 23:55. The fastest bus covers the 518 miles (834 km) distance in 19h 10m.
Distance 518 miles (834 km) |
Average bus duration 19h 16m |
Cheapest ticket price $133 (€109) |
Buses per day 3 |
Fastest bus 19h 10m |
First bus 2:23 AM |
Last bus 11:55 PM |
Cheapest Month May |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Apr - Jun |
Discover the best of Detroit — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Detroit trip today.
Major fine arts museum known for its encyclopedic collection and Diego Rivera’s Detroit Industry Murals.
Large museum in the Detroit area showcasing transportation, industry, design, and iconic American artifacts.
Historic Hitsville U.S.A. museum preserving the story of Motown Records and its legendary artists.
Popular waterfront promenade with skyline views, public art, and easy walking between downtown and riverfront parks.
Island park with gardens, trails, water views, and several cultural attractions, popular with locals and visitors.
Historic market district famous for murals, weekend markets, and one of Detroit’s strongest local atmospheres.
A rectangular, deep-pan pizza with a thick yet airy crust, caramelized cheese edges, and sauce layered on top. It is one of Detroit’s most iconic local foods.
A hot dog in a bun topped with chili, mustard, and chopped onions. The Detroit coney is a classic local fast-food staple tied to the city’s Greek-American diner tradition.
A traditional Detroit float made with Vernors ginger ale and vanilla ice cream. Despite the name, it is a distinctly Detroit dessert drink.
A long-running Hamtramck favorite for hearty Polish dishes in a warm, traditional basement setting near Detroit.
A respected modern Detroit restaurant known for seasonal small plates, strong cocktails, and an upscale but relaxed atmosphere.
A polished downtown dining room in the Detroit Foundation Hotel, known for contemporary American cooking and stylish surroundings.
Moderate for U.S. city travel. Hotels vary widely, while casual dining, coffee, and local transport are usually manageable for most visitors.
Tip 18-20% in restaurants before tax. Bartenders: USD 1-2 per drink. Taxis/rideshares: 10-15%. Hotel staff: USD 1-5. Not usually expected for counter service, but appreciated.
Find answers to the most common questions about traveling from Greenville, SC to Detroit, MI by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Detroit, MI, this guide helps you travel smarter and with confidence.

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