- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
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The cheapest and fastest buses from Buffalo, NY to Charleston, SC
Showing times and prices for Aug 05
Cheapest price
$127
Average price
$142
Fastest journey
1 d 6 h
Average duration
1 d 8 h 32 m
Buses per day
7
Distance
1128 km
Cheap tickets
The best way to find a cheap bus ticket from Buffalo, NY to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Buffalo, NY to Charleston, SC will cost around $142 if you buy it on the day, but the cheapest tickets can be found for only $127.
Fast buses
It's difficult to get from Buffalo, NY to Charleston, SC without transferring at least 2 times.
· · 3:40 PM30h00Buffalo, NFTA Metro Center9:40 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$1271One-way2 transfers
FlixBus · FlixBus+ · 1:05 PM32h35Cheektowaga, BNIA Drway & BNIA Terminal9:40 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$1301One-way3 transfers- FlixBus · FlixBus+ · 11:00 PM37h45Buffalo, NFTA Metro Center12:45 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$1391One-way3 transfers
- FlixBus · FlixBus+ · 11:20 PM37h25Cheektowaga, BNIA Drway & BNIA Terminal12:45 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$1431One-way3 transfers
- FlixBus+ · · 10:30 AM32h00Buffalo, NFTA Metro Center6:30 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$1431One-way3 transfers
- · · 3:40 PM30h00Buffalo, NFTA Metro Center9:40 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$1271One-way2 transfers
- FlixBus · FlixBus+ · 10:50 AM31h40Cheektowaga, BNIA Drway & BNIA Terminal6:30 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$1611One-way4 transfers
- FlixBus+ · · 10:30 AM32h00Buffalo, NFTA Metro Center6:30 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$1431One-way3 transfers
- FlixBus · FlixBus+ · 1:05 PM32h35Cheektowaga, BNIA Drway & BNIA Terminal9:40 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$1301One-way3 transfers
- FlixBus · FlixBus+ · 12:20 AM36h25Cheektowaga, BNIA Drway & BNIA Terminal12:45 PMCharleston, Gaynor Avenue (Greyhound Bus Station), SC$1491One-way3 transfers
Journey information
Overview: Bus from Buffalo, NY to Charleston, SC
USAUSA
Take a bus from Buffalo, NY to Charleston, SC and enjoy the approximately 700 miles (1128 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 08:45, the last at 23:55.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 700 miles (1128 km) |
Buses per day 5 |
First bus 8:45 AM |
Last bus 11:55 PM |
Cheapest Month May |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Jan - Mar |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Buffalo, NY to Charleston, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:20AM | Arrival Time 12:45PM | Duration 36h25 | Departure days Wed, Thu | Cheapest price $148 |
Operator FlixBus | Departure Time 03:30AM | Arrival Time 12:45PM | Duration 33h15 | Departure days Tue | Cheapest price $179 |
Operator FlixBus | Departure Time 03:50AM | Arrival Time 12:45PM | Duration 32h55 | Departure days Tue | Cheapest price $166 |
Operator FlixBus | Departure Time 05:30AM | Arrival Time 12:45PM | Duration 31h15 | Departure days Fri, Sat, Sun | Cheapest price $119 |
Operator FlixBus | Departure Time 05:45AM | Arrival Time 12:45PM | Duration 31h00 | Departure days Fri, Sat, Sun | Cheapest price $121 |
Operator Greyhound | Departure Time 10:30AM | Arrival Time 06:30PM | Duration 32h00 | Departure days Tue, Wed, Thu, Fri, Sat | Cheapest price $127 |
Operator Greyhound | Departure Time 10:50AM | Arrival Time 06:30PM | Duration 31h40 | Departure days Tue, Fri, Sat, Sun | Cheapest price $124 |
Operator FlixBus | Departure Time 10:50AM | Arrival Time 06:30PM | Duration 31h40 | Departure days Wed, Thu | Cheapest price $156 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 09:40PM | Duration 32h35 | Departure days Tue, Thu, Fri, Sat | Cheapest price $135 |
Operator Greyhound | Departure Time 01:05PM | Arrival Time 09:40PM | Duration 32h35 | Departure days Wed, Sun | Cheapest price $130 |
Operator Greyhound | Departure Time 03:40PM | Arrival Time 09:40PM | Duration 30h00 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $122 |
Operator FlixBus | Departure Time 11:00PM | Arrival Time 12:45PM | Duration 37h45 | Departure days Tue, Wed | Cheapest price $139 |
Operator Greyhound | Departure Time 11:20PM | Arrival Time 12:45PM | Duration 37h25 | Departure days Tue, Wed, Thu, Sun | Cheapest price $121 |
Operator FlixBus | Departure Time 11:20PM | Arrival Time 12:45PM | Duration 37h25 | Departure days Fri, Sat | Cheapest price $139 |
Operator FlixBus | Departure Time 11:59PM | Arrival Time 12:45PM | Duration 36h46 | Departure days Thu, Fri, Sat, Sun | Cheapest price $121 |
Live departures
Buffalo, NY to Charleston, SC bus times
The table below shows live departures for Buffalo, NY to Charleston, SC buses for today, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus · FlixBus+ | 3:50 AM Cheektowaga, BNIA Drway & BNIA Terminal | 32h55 | 12:45 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
| FlixBus+ · · | 10:30 AM Buffalo, NFTA Metro Center | 32h00 | 6:30 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
| FlixBus+ · · | 10:50 AM Cheektowaga, BNIA Drway & BNIA Terminal | 31h40 | 6:30 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
| FlixBus · FlixBus+ · | 1:05 PM Cheektowaga, BNIA Drway & BNIA Terminal | 32h35 | 9:40 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
| · · | 3:40 PM Buffalo, NFTA Metro Center | 30h00 | 9:40 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 2 transfers | |
| FlixBus++FlixBus+ | 11:00 PM Buffalo, NFTA Metro Center | 37h45 | 12:45 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
| FlixBus · FlixBus+ · | 11:20 PM Cheektowaga, BNIA Drway & BNIA Terminal | 37h25 | 12:45 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
| Wednesday, August 5 | |||||
| FlixBus · FlixBus+ · | 12:20 AM Cheektowaga, BNIA Drway & BNIA Terminal | 36h25 | 12:45 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Complete guide to Charleston, SC
Things to do in Charleston, SC
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
- Must visit
Gibbes Museum of Art
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
- Must visit
International African American Museum
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
- Must visit
The Battery
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
- Must visit
East Battery
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
- Must visit
Charleston City Market
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
- Gluten-free
Perloo
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
- Gluten-free
Shrimp And Grits
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
She-Crab Soup
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Circa 1886 Restaurant
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
The Ordinary
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Magnolias
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
US Dollar ($)
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Average meal costs
- Budget
- $10-18 for fast food or casual lunch.
- Mid-range
- $25-45 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale restaurants.
- Coffee
- $4-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
FAQs: Bus from Buffalo, NY to Charleston, SC
Find answers to the most common questions about traveling from Buffalo, NY to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.
The earliest bus from Buffalo, NY to Charleston, SC leaves at 8:45 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Buffalo, NY to Charleston, SC leaves at 11:55 PM.
Yes, you can take a between Buffalo, NY and Charleston, SC.
No, there are no bathrooms on board the bus from Buffalo, NY to Charleston, SC.
No, the bus from Buffalo, NY to Charleston, SC has no accessibility options.
No, bikes are not allowed on board the bus from Buffalo, NY to Charleston, SC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Buffalo, NY to Charleston, SC.
No, luggage for the bus from Buffalo, NY to Charleston, SC needs to be booked in addition.
No, there are no additional luggage options for the bus from Buffalo, NY to Charleston, SC.
Unfortunately, pets are not allowed on the bus from Buffalo, NY to Charleston, SC.
No, there are no USB plugs on board the bus from Buffalo, NY to Charleston, SC.
No, there is no WiFi on board the bus from Buffalo, NY to Charleston, SC.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Charleston, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like the historic district and popular tourist spots. Beware of overly aggressive street vendors and unofficial taxi services that may overcharge. Additionally, travelers should avoid leaving valuables unattended and be cautious when using ride-sharing apps to ensure the driver matches the booking details. Staying aware of surroundings and using authorized services helps minimize safety risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Buffalo, NY to Charleston, SC
Most Buffalo, NY to Charleston, SC buses use the Cheektowaga, BNIA Drway & BNIA Terminal to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Buffalo, NY and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Buffalo
Arrival bus stations in Charleston
Cheektowaga, BNIA Drway & BNIA Terminal
City-centre transport
Getting to Cheektowaga, BNIA Drway & BNIA Terminal from Buffalo city centre
BusAdt N809 · 10m · $7
24, 78 · 31m · $2 · every ~4 min
24, 78 · 46m · $2 · every ~4 min
Buffalo, NFTA Metro Center
Charleston, Gaynor Avenue (Greyhound Bus Station)
City-centre transport
Getting to Charleston, Gaynor Avenue (Greyhound Bus Station) from Charleston city centre
Bus10 · 32m · every ~4 min
10 · 41m · every ~4 min
Most popular bus connections from Buffalo, NY
More options for your journey from Buffalo, NY to Charleston, SC
Here are some other resources that might have the information you need
Most popular buses to and from Charleston, SC and Buffalo, NY
Most popular bus connections to Charleston, SC
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