- Must visit
Orlando Science Center
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
Cheapest price on Oct 21
$86
Average ticket price on Oct 21
$87
Fastest journey on Oct 21
11 h 30 m
Average journey duration on Oct 21
15 h 46 m
Buses on Oct 21
4
Distance
709 km
The best way to find a cheap bus ticket from Greenville, SC to Orlando, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Orlando, FL will cost around $87 if you buy it on the day, but the cheapest tickets can be found for only $86.
It's difficult to get from Greenville, SC to Orlando, FL without transferring at least once.
+
FlixBus
+
FlixBus
+
FlixBus
FlixBus+
+
FlixBus
+
FlixBus
+
FlixBus
+
FlixBus
FlixBus+
+
FlixBusBuses from Greenville, SC to Orlando, FL run on average 7 times per day, taking around 12h 26m. Cheap bus tickets for this journey start at $67 if you book in advance.
The earliest bus runs at 04:00, the last at 23:40. The fastest bus covers the 440 miles (709 km) distance in 10h 15m.
Distance 440 miles (709 km) |
Average bus duration 12h 26m |
Cheapest ticket price $67 |
Buses per day 7 |
Fastest bus 10h 15m |
First bus 4:00 AM |
Last bus 11:40 PM |
Cheapest Month Oct |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 28 days |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 07:10AM | Arrival Time 09:15PM | Duration 14h05 | Departure days Everyday | Cheapest price $70 |
Operator FlixBus | Departure Time 11:15AM | Arrival Time 11:59PM | Duration 12h44 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $69 |
Operator FlixBus | Departure Time 01:20PM | Arrival Time 01:50AM | Duration 12h30 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $69 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 05:50AM | Duration 15h05 | Departure days Everyday | Cheapest price $69 |
Operator FlixBus | Departure Time 08:20PM | Arrival Time 02:55PM | Duration 18h35 | Departure days Everyday | Cheapest price $71 |
Operator Greyhound | Departure Time 08:20PM | Arrival Time 05:20PM | Duration 21h00 | Departure days Mon | Cheapest price $72 |
Operator Greyhound | Departure Time 09:35PM | Arrival Time 04:20PM | Duration 18h45 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $75 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 08:00PM | Duration 22h25 | Departure days Tue, Wed | Cheapest price $72 |
The table below shows live departures for Greenville, SC to Orlando, FL buses for today, Tuesday, October 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+![]() | 7:10 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 14h05 | 9:15 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
FlixBus+![]() | 11:15 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 12h05 | 11:20 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
FlixBus+![]() | 11:15 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 12h44 | 11:59 PM Orlando, The Florida Mall, FL | 1 transfer | |
FlixBus · FlixBus | 1:20 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 12h30 | 1:50 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
FlixBus+![]() | 2:45 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 15h05 | 5:50 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
FlixBus+![]() | 8:20 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 11h30 | 7:50 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
FlixBus · FlixBus+![]() | 9:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 22h25 | 8:00 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Orlando, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Orlando, FL trip today.
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
Major local history museum in a restored 1927 courthouse, covering Central Florida's past through engaging permanent and special exhibits.
Smithsonian-affiliated art museum with American, African, and ancient works, plus strong rotating exhibitions in Winter Park.
Orlando's signature urban park with lake views, swan boats, skyline scenes, and frequent festivals in the city center.
Upscale main street area famous for boutiques, brick streets, and a polished small-town atmosphere in nearby Winter Park.
Lively entertainment district with nightlife, murals, and historic architecture around downtown's Church Street corridor.
A Central Florida favorite of smoked or fried local catfish, often served with hushpuppies and grits. It reflects the region's freshwater fishing and Southern roots.
Fresh Atlantic or Gulf shrimp, commonly peel-and-eat, grilled, or fried. It is a staple across Florida and prized in Orlando seafood spots for its regional freshness.
Cuban coffee sweetened during brewing for a bold, syrupy shot. Popular in Central Florida's Latin communities, it is a daily ritual and local caffeine classic.
Popular Cuban cafe serving strong cafecito, Cuban sandwiches, and pastries in a busy, no-frills neighborhood setting.
Historic casual seafood house known for Florida gator tail, frog legs, and laid-back Old Florida charm near downtown Orlando.
Refined restaurant in Winter Park highlighting Florida seafood and seasonal Southern ingredients in an elegant but relaxed space.
Moderate for a major US tourist city. Theme parks and hotels raise trip costs, while casual dining and ride-hailing are widely available at typical US urban prices.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis or ride-hailing, and small change or up to 10% at cafes if table service is provided.
Find answers to the most common questions about traveling from Greenville, SC to Orlando, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.

Most Greenville, SC to Orlando, FL buses use the Greenville, Woodruff Rd ("Raceway" gas station) to Orlando, N John Young Pkwy (Greyhound Bus Station) station pair, with some services arriving at Orlando, The Florida Mall. Use this guide to compare Greenville, SC and Orlando, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Greenville, Woodruff Rd ("Raceway" gas station) is 8 km from Greenville city centre. Public transport options include:
Greenville, Woodruff Rd ("Raceway" gas station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Limited dining options available in adjacent areas.
Wi-Fi is available at Greenville, Woodruff Rd ("Raceway" gas station). ATMs are available at Greenville, Woodruff Rd ("Raceway" gas station).
Ticket office support is available at Greenville, Woodruff Rd ("Raceway" gas station).
Available at Greenville, Woodruff Rd ("Raceway" gas station): Parking, Taxis, WC.
Accessibility facilities are available at Greenville, Woodruff Rd ("Raceway" gas station): Basic access available for persons with disabilities.
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.
Here are some other resources that might have the information you need