- Must visit
Orlando Science Center
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
Cheapest price
$87
Average price
$94
Fastest journey
11 h 30 m
Average duration
15 h 36 m
Buses per day
5
Distance
709 km
The best way to find a cheap bus ticket from Greenville, SC to Orlando, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Orlando, FL will cost around $94 if you buy it on the day, but the cheapest tickets can be found for only $87.
It's difficult to get from Greenville, SC to Orlando, FL without transferring at least once.
FlixBus+
FlixBus+
FlixBus · FlixBus+
FlixBus+
FlixBus · FlixBus+
FlixBus+
FlixBus+
FlixBus+
FlixBus · FlixBus+
FlixBus · FlixBus+
Omio recommends booking the train as it is the most popular option from Greenville, SC to Orlando, FL among Omio's users. If you are prioritising price take the bus with prices starting from $63. For those with little time consider booking a flight which can get you there in 2h 38m. The ticket price range depends on the travel mode: a bus costs an average of $63, and a train costs an average of $109.
Distance: 440 miles (709 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$100 Average price Cheapest | $177 Average price | $177 Average price | $83 Average price (fuel + tolls) |
15h 40m Average total duration 15h 10m Onboard + 30m Additional time* | 28h 54m Average total duration 28h 24m Onboard + 30m Additional time* | 5h 38m Average total duration Fastest 2h 38m Onboard + 3h 0m Additional time* | 7h 36m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greenville, SC to Orlando, FL:
A bus is $76 (€76) less than a flight for this route with tickets for a flight from Greenville, SC to Orlando, FL costing on average $177 (€177).
A bus is $77 (€77) less than a train for this route with tickets for a train from Greenville, SC to Orlando, FL costing on average $177 (€177).
Other travel options to Orlando, FL take longer:
Bus takes on average 15h 10m.
Train takes on average 28h 24m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 07:10AM | Arrival Time 09:15PM | Duration 14h05 | Departure days Everyday | Cheapest price $74 |
Operator FlixBus | Departure Time 11:15AM | Arrival Time 11:59PM | Duration 12h44 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $74 |
Operator FlixBus | Departure Time 01:20PM | Arrival Time 01:50AM | Duration 12h30 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $74 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 05:50AM | Duration 15h05 | Departure days Everyday | Cheapest price $76 |
Operator FlixBus | Departure Time 08:20PM | Arrival Time 02:55PM | Duration 18h35 | Departure days Everyday | Cheapest price $81 |
Operator Greyhound | Departure Time 09:35PM | Arrival Time 04:20PM | Duration 18h45 | Departure days Everyday | Cheapest price $84 |
The table below shows live departures for Greenville, SC to Orlando, FL buses for today, Tuesday, July 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 1:20 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 12h30 | 1:50 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
+ FlixBus | 2:45 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 15h05 | 5:50 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
+ FlixBus | 8:20 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 11h30 | 7:50 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
FlixBus · FlixBus+![]() | 9:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 18h45 | 4:20 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 2 transfers | |
| Wednesday, July 22 | |||||
FlixBus+![]() | 7:10 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 14h05 | 9:15 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Greenville, SC to Orlando, FL run on average 6 times per day, taking around 15h 10m. Cheap bus tickets for this journey start at $63 (€63) if you book in advance.
The earliest bus runs at 04:00, the last at 23:40. The fastest bus covers the 440 miles (709 km) distance in 11h 15m.
Distance 440 miles (709 km) |
Average bus duration 15h 10m |
Cheapest ticket price $63 (€63) |
Buses per day 6 |
Fastest bus 11h 15m |
First bus 4:00 AM |
Last bus 11:40 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Jul - Sep |
Discover the best of Orlando — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Orlando trip today.
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
Major local history museum in a restored 1927 courthouse, covering Central Florida's past through engaging permanent and special exhibits.
Smithsonian-affiliated art museum with American, African, and ancient works, plus strong rotating exhibitions in Winter Park.
Orlando's signature urban park with lake views, swan boats, skyline scenes, and frequent festivals in the city center.
Upscale main street area famous for boutiques, brick streets, and a polished small-town atmosphere in nearby Winter Park.
Lively entertainment district with nightlife, murals, and historic architecture around downtown's Church Street corridor.
A Central Florida favorite of smoked or fried local catfish, often served with hushpuppies and grits. It reflects the region's freshwater fishing and Southern roots.
Fresh Atlantic or Gulf shrimp, commonly peel-and-eat, grilled, or fried. It is a staple across Florida and prized in Orlando seafood spots for its regional freshness.
Cuban coffee sweetened during brewing for a bold, syrupy shot. Popular in Central Florida's Latin communities, it is a daily ritual and local caffeine classic.
Popular Cuban cafe serving strong cafecito, Cuban sandwiches, and pastries in a busy, no-frills neighborhood setting.
Historic casual seafood house known for Florida gator tail, frog legs, and laid-back Old Florida charm near downtown Orlando.
Refined restaurant in Winter Park highlighting Florida seafood and seasonal Southern ingredients in an elegant but relaxed space.
Moderate for a major US tourist city. Theme parks and hotels raise trip costs, while casual dining and ride-hailing are widely available at typical US urban prices.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis or ride-hailing, and small change or up to 10% at cafes if table service is provided.
Find answers to the most common questions about traveling from Greenville, SC to Orlando, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.

Most Greenville, SC to Orlando, FL buses use the Greenville, Woodruff Rd ("Raceway" gas station) to Orlando, N John Young Pkwy (Greyhound Bus Station) station pair, with some services arriving at Orlando, The Florida Mall. Use this guide to compare Greenville, SC and Orlando, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need