The cheapest and fastest buses from Greenville, SC to Orlando, FL
Cheapest price
$159
Average price
$159
Fastest journey
11 h 15 m
Average duration
11 h 15 m
Buses per day
1
Distance
709 km
The best way to find a cheap bus ticket from Greenville, SC to Orlando, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Orlando, FL will cost around $159 if you buy it on the day, but the cheapest tickets can be found for only $159.
Of the 1 buses that leave Greenville, SC for Orlando, FL on Sun, Mar 08, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Mar 08 the direct buses cover the 709 km distance in an average of 11 h 15 m but if you time it right, some buses will get you there in just 11 h 15 m .
On Sun, Mar 08 the slowest buses will take 11 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for Greenville, SC to Orlando, FL
Omio recommends booking the train as it is the most popular option from Greenville, SC to Orlando, FL among Omio's users. If you are prioritising price take the bus with prices starting from $90. For those with little time consider booking a flight which can get you there in 2h 38m. The ticket price range depends on the travel mode: a bus costs an average of $90, and a train costs an average of $135.
Distance: 440 miles (709 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$148 Average price Cheapest | $244 Average price | $206 Average price |
15h 40m Average total duration 15h 10m Onboard + 30m Additional time* | 28h 54m Average total duration 28h 24m Onboard + 30m Additional time* | 5h 38m Average total duration Fastest 2h 38m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Greenville, SC to Orlando, FL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 08
Mar 09
Mar 10
Mar 11
Mar 12
Mar 13
Mar 14
Why should you book Greenville, SC to Orlando, FL buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Greenville, SC to Orlando, FL.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Greenville, SC to Orlando, FL.
Journey information
Overview: Bus from Greenville, SC to Orlando, FL
Buses from Greenville, SC to Orlando, FL run on average 6 times per day, taking around 15h 10m. Cheap bus tickets for this journey start at $90 (€73) but you can travel from only $85 (€69) by flight.
The earliest bus runs at 04:00, the last at 23:40. The fastest bus covers the 440 miles (709 km) distance in 12h 5m.
Distance 440 miles (709 km) |
Average bus duration 15h 10m |
Cheapest ticket price $90 (€73) |
Buses per day 6 |
Fastest bus 12h 5m |
First bus 04:00 |
Last bus 23:40 |
Cheapest month Sep |
Cheapest day Tue |
High season Jan - Mar |
Low season Apr - Jun |
Bus providers: FlixBus from Greenville, SC to Orlando, FLYou can travel by bus between Greenville, SC to Orlando, FL with FlixBus for as low as $85 (€69). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Greenville, SC to Orlando, FL
Find answers to the most common questions about traveling from Greenville, SC to Orlando, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Walt Disney World Resort, a massive entertainment complex featuring theme parks, water parks, and resorts
- Universal Orlando Resort, a popular destination with thrilling rides, shows, and attractions based on movies and TV shows
- SeaWorld Orlando, a marine-themed park offering animal exhibits, shows, and rides
- Kennedy Space Center Visitor Complex, an educational attraction showcasing NASA's space exploration history and offering interactive exhibits
- Leu Gardens, a beautiful botanical garden with a variety of plant collections and scenic landscapes.
- ICON Park, a vibrant entertainment complex with dining, shopping, and the iconic Wheel for panoramic views
- Explore the vibrant nightlife and live entertainment at Church Street District
- Enjoy a day of shopping and dining at The Mall at Millenia
- Experience the natural beauty and wildlife at Wekiwa Springs State Park
- Visit the Orlando Science Center for interactive exhibits and planetarium shows.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Greenville, SC to Orlando, FL
Most popular bus connections from Greenville, SC
More options for your journey from Greenville, SC to Orlando, FL
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