Travel Information
Compare bus, train, and flight for Greenville, SC to Philadelphia, PA
Omio recommends booking the train as it is the most popular option from Greenville, SC to Philadelphia, PA among Omio's users. If you are prioritising price take the bus with prices starting from €145. For those with little time consider booking a flight which can get you there in 2h 24m. The ticket price range depends on the travel mode: a bus costs an average of €145, and a flight costs an average of €370.
Distance: 530 miles (854 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€154 Average price Cheapest | €261 Average price | €383 Average price |
14h 33m Average total duration 14h 3m Onboard + 30m Additional time* | 14h 27m Average total duration 13h 57m Onboard + 30m Additional time* | 5h 24m Average total duration Fastest 2h 24m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Greenville, SC to Philadelphia, PA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Greenville, SC to Philadelphia, PA buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Greenville, SC to Philadelphia, PA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Greenville, SC to Philadelphia, PA.
Why book with Omio over Wanderu?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from Greenville, SC to Philadelphia, PA.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Greenville, SC to Philadelphia, PA.
Journey information
Overview: Bus from Greenville, SC to Philadelphia, PA
Buses from Greenville, SC to Philadelphia, PA run on average 12 times per day, taking around 14h 3m. Cheap bus tickets for this journey start at $183 (€145) if you book in advance.
The earliest bus runs at 01:50, the last at 23:30. The fastest bus covers the 530 miles (854 km) distance in 13h 45m.
Distance 530 miles (854 km) |
Average bus duration 14h 3m |
Cheapest ticket price $183 (€145) |
Buses per day 12 |
Fastest bus 13h 45m |
First bus 01:50 |
Last bus 23:30 |
Bus providers: Greyhound, FlixBus from Greenville, SC to Philadelphia, PAYou can travel by bus between Greenville, SC to Philadelphia, PA with Greyhound, FlixBus for as low as $183 (€145). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Greenville, SC to Philadelphia, PA
Find answers to the most common questions about traveling from Greenville, SC to Philadelphia, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Philadelphia, PA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Liberty Bell, an iconic symbol of American independence housed in Liberty Bell Center
- Independence Hall, the birthplace of the United States where the Declaration of Independence and Constitution were signed
- Philadelphia Museum of Art, renowned for its vast collection of art and famous Rocky Steps
- Reading Terminal Market, a historic public market offering diverse food vendors and local specialties
- Eastern State Penitentiary, a former prison now a museum known for its grand architecture and historical significance.
- Liberty Bell, an iconic symbol of American independence located in the Liberty Bell Center
- Independence Hall, the historic site where the Declaration of Independence and the U.S. Constitution were debated and adopted
- Philadelphia Museum of Art, renowned for its vast collection of art and the famous Rocky Steps
- Reading Terminal Market, a bustling indoor market offering diverse food options and local specialties
- Philadelphia Zoo, America's first zoo featuring a wide variety of animals and interactive exhibits.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Greenville, SC to Philadelphia, PA
Most popular bus connections from Greenville, SC
More options for your journey from Greenville, SC to Philadelphia, PA
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