- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Cheapest price
€143
Average price
€171
Fastest journey
23 h 35 m
Average duration
1 d 3 h 44 m
Buses per day
4
Distance
852 km
The best way to find a cheap bus ticket from Pittsburgh, PA to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pittsburgh, PA to Charleston, SC will cost around €171 if you buy it on the day, but the cheapest tickets can be found for only €143.
It's difficult to get from Pittsburgh, PA to Charleston, SC without transferring at least 2 times.
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Omio recommends booking the flight as it is the most popular option from Pittsburgh, PA to Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from €119. For those with little time consider booking a flight which can get you there in 2h 30m. The ticket price range depends on the travel mode: a bus costs an average of €119, and a train costs an average of €192.
Distance: 529 miles (852 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
€178 Average price Cheapest | €200 Average price | €217 Average price | €108 Average price (fuel + tolls) |
22h 30m Average total duration 22h 0m Onboard + 30m Additional time* | 5h 30m Average total duration Fastest 2h 30m Onboard + 3h 0m Additional time* | 21h 48m Average total duration 21h 18m Onboard + 30m Additional time* | 10h 7m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Pittsburgh, PA to Charleston, SC:
A bus is €22 less than a flight for this route with tickets for a flight from Pittsburgh, PA to Charleston, SC costing on average €200.
A bus is €39 less than a train for this route with tickets for a train from Pittsburgh, PA to Charleston, SC costing on average €217.
Other travel options to Charleston, SC take longer:
Train takes on average 21h 18m.
Bus takes on average 22h 0m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:35AM | Arrival Time 09:25AM | Duration 31h50 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price €92 |
Operator Greyhound | Departure Time 08:00AM | Arrival Time 12:45PM | Duration 28h45 | Departure days Wed | Cheapest price €143 |
Operator Greyhound | Departure Time 12:00PM | Arrival Time 12:15PM | Duration 24h15 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price €91 |
Operator Greyhound | Departure Time 06:50PM | Arrival Time 06:30PM | Duration 23h40 | Departure days Tue, Sat | Cheapest price €86 |
Operator Greyhound | Departure Time 06:55PM | Arrival Time 06:30PM | Duration 23h35 | Departure days Everyday | Cheapest price €84 |
Operator Greyhound | Departure Time 07:05PM | Arrival Time 09:50PM | Duration 26h45 | Departure days Wed, Thu | Cheapest price €222 |
The table below shows live departures for Pittsburgh, PA to Charleston, SC buses for today, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· + FlixBus+![]() | 1:35 AM Pittsburgh, Greyhound Bus Station, PA | 31h50 | 9:25 AM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
FlixBus+ · | 12:00 PM Pittsburgh, Greyhound Bus Station, PA | 24h45 | 12:45 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 2 transfers | |
· · · | 6:50 PM Pittsburgh, Greyhound Bus Station, PA | 23h40 | 6:30 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
+ FlixBus+ · | 6:55 PM Pittsburgh, Greyhound Bus Station, PA | 26h45 | 9:40 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Pittsburgh, PA to Charleston, SC run on average 1 times per day, taking around 22h 0m. Cheap bus tickets for this journey start at €119 but you can travel from only €66 by flight.
The earliest bus runs at 11:15, the last at 21:00. The fastest bus covers the 529 miles (852 km) distance in 22h 0m.
Distance 529 miles (852 km) |
Average bus duration 22h 0m |
Cheapest ticket price €119 |
Buses per day 1 |
Fastest bus 22h 0m |
First bus 11:15 AM |
Last bus 9:00 PM |
Cheapest Month Apr |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Jan - Mar |
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
Find answers to the most common questions about traveling from Pittsburgh, PA to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

Most Pittsburgh, PA to Charleston, SC buses use the Pittsburgh, Greyhound Bus Station to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Pittsburgh, PA and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need