- Must visit
The Charleston Museum
Often called America's first museum, it covers Charleston and Lowcountry history, decorative arts, natural history, and regional culture.
Cheapest price
$152
Average price
$152
Fastest journey
22 h
Average duration
22 h
Buses per day
1
Distance
852 km
The best way to find a cheap bus ticket from Pittsburgh, PA to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pittsburgh, PA to Charleston, SC will cost around $152 if you buy it on the day, but the cheapest tickets can be found for only $152.
Of the 1 buses that leave Pittsburgh, PA for Charleston, SC on Sun, Jun 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct buses cover the 852 km distance in an average of 22 h but if you time it right, some buses will get you there in just 22 h .
On Sun, Jun 21 the slowest buses will take 22 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the flight as it is the most popular option from Pittsburgh, PA to Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from $146. For those with little time consider booking a flight which can get you there in 2h 30m. The ticket price range depends on the travel mode: a bus costs an average of $146, and a train costs an average of $235.
Distance: 529 miles (852 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$218 Average price Cheapest | $245 Average price | $266 Average price | $132 Average price (fuel + tolls) |
22h 30m Average total duration 22h 0m Onboard + 30m Additional time* | 5h 30m Average total duration Fastest 2h 30m Onboard + 3h 0m Additional time* | 21h 48m Average total duration 21h 18m Onboard + 30m Additional time* | 10h 7m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Pittsburgh, PA to Charleston, SC:
A bus is $27 (€22) less than a flight for this route with tickets for a flight from Pittsburgh, PA to Charleston, SC costing on average $245 (€200).
A bus is $48 (€39) less than a train for this route with tickets for a train from Pittsburgh, PA to Charleston, SC costing on average $266 (€217).
Other travel options to Charleston, SC take longer:
Train takes on average 21h 18m.
Bus takes on average 22h 0m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:30AM | Arrival Time 11:30PM | Duration 22h00 | Departure days Sun | Cheapest price $152 |
Operator Greyhound | Departure Time 06:50PM | Arrival Time 06:30PM | Duration 23h40 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $117 |
The table below shows live departures for Pittsburgh, PA to Charleston, SC buses for today, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · · | 6:50 PM Pittsburgh, Greyhound Bus Station, PA | 23h40 | 6:30 PM Charleston, Gaynor Avenue (Greyhound Bus Station), SC | 3 transfers | |
| Saturday, June 20 | |||||
![]() | 1:30 AM Pittsburgh, PA | 22h00 | 11:30 PM Charleston, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Pittsburgh, PA to Charleston, SC run on average 1 times per day, taking around 22h 0m. Cheap bus tickets for this journey start at $146 (€119) but you can travel from only $81 (€66) by flight.
The earliest bus runs at 11:15, the last at 21:00. The fastest bus covers the 529 miles (852 km) distance in 22h 0m.
Distance 529 miles (852 km) |
Average bus duration 22h 0m |
Cheapest ticket price $146 (€119) |
Buses per day 1 |
Fastest bus 22h 0m |
First bus 11:15 AM |
Last bus 9:00 PM |
Cheapest Month Apr |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Jan - Mar |
Discover the best of Charleston — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston trip today.
Often called America's first museum, it covers Charleston and Lowcountry history, decorative arts, natural history, and regional culture.
A small but important museum interpreting the domestic slave trade in Charleston through exhibits in a historic market building.
Charleston's leading art museum, known for American art with strong ties to the South, rotating exhibitions, and a distinguished permanent collection.
Charleston's famous waterfront promenade is lined with grand historic homes, harbor views, and classic postcard scenery.
A popular riverfront park known for its pier, lawns, and the photogenic Pineapple Fountain.
Charleston's best-known commercial corridor, mixing historic architecture, shopping, nightlife, and frequent social media visibility.
A Lowcountry classic of sautéed shrimp served over creamy grits, often with bacon or gravy. It is one of Charleston’s signature dishes.
A rich Charleston soup made with crab meat, crab roe, cream, and sherry. It is a historic local specialty associated with the city’s coastal cuisine.
A traditional rice and field pea dish, usually cooked with pork for flavor. It is an iconic Southern and Lowcountry comfort food.
One of Charleston’s most acclaimed restaurants, serving ingredient-driven Southern cuisine with a polished but approachable feel. Reservations are highly sought after.
A popular waterfront restaurant known for Lowcountry seafood, shrimp and grits, and relaxed harbor views. It is a dependable choice for classic Charleston flavors.
A celebrated restaurant focused on refined Southern cooking using seasonal local ingredients. Stylish and upscale, it is one of Charleston’s best-known dining rooms.
Prices are moderate by U.S. standards. Historic district dining and hotels cost more, while casual food and transport stay manageable.
Tip 18-20% in restaurants. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and valet. Tipping is expected for most service roles.
Find answers to the most common questions about traveling from Pittsburgh, PA to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

Most Pittsburgh, PA to Charleston, SC buses use the Pittsburgh, Greyhound Bus Station to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Pittsburgh, PA and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need