- Must visit
Museum of Fine Arts, Boston
One of the largest art museums in the United States, known for its encyclopedic collection spanning ancient to contemporary works.
Cheapest price
$161
Average price
$172
Fastest journey
21 h 10 m
Average duration
22 h 24 m
Buses per day
5
Distance
1289 km
The best way to find a cheap bus ticket from Greenville, SC to Boston, MA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Boston, MA will cost around $172 if you buy it on the day, but the cheapest tickets can be found for only $161.
It's difficult to get from Greenville, SC to Boston, MA without transferring at least once.
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FlixBus · FlixBusOmio recommends booking the bus as it is the most popular option from Greenville, SC to Boston, MA among Omio's users. If you are prioritising price take the bus with prices starting from $214. For those with little time consider booking a flight which can get you there in 7h 8m. The ticket price range depends on the travel mode: a bus costs an average of $214, and a train costs an average of $1074.
Distance: 800 miles (1289 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$247 Average price Cheapest | $1074 Average price | $508 Average price | $184 Average price (fuel + tolls) |
20h 49m Average total duration 20h 19m Onboard + 30m Additional time* | 20h 7m Average total duration 19h 37m Onboard + 30m Additional time* | 10h 8m Average total duration Fastest 7h 8m Onboard + 3h 0m Additional time* | 14h 17m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greenville, SC to Boston, MA:
A bus is $260 (€213) less than a flight for this route with tickets for a flight from Greenville, SC to Boston, MA costing on average $508 (€416).
A bus is $827 (€676) less than a train for this route with tickets for a train from Greenville, SC to Boston, MA costing on average $1074 (€879).
Other travel options to Boston, MA take longer:
Train takes on average 19h 37m.
Bus takes on average 20h 19m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:25AM | Arrival Time 04:40AM | Duration 25h15 | Departure days Everyday | Cheapest price $120 |
Operator Greyhound | Departure Time 07:10AM | Arrival Time 05:10AM | Duration 22h00 | Departure days Everyday | Cheapest price $120 |
Operator Greyhound | Departure Time 11:00AM | Arrival Time 09:25AM | Duration 22h25 | Departure days Tue, Wed | Cheapest price $159 |
Operator FlixBus | Departure Time 12:15PM | Arrival Time 09:25AM | Duration 21h10 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $136 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 02:35PM | Duration 22h20 | Departure days Everyday | Cheapest price $126 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 06:50PM | Duration 21h15 | Departure days Everyday | Cheapest price $129 |
The table below shows live departures for Greenville, SC to Boston, MA buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ · | 4:15 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 22h20 | 2:35 PM Boston, Bus Terminal South Station | 2 transfers | |
FlixBus · FlixBus | 9:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 21h15 | 6:50 PM Boston, Bus Terminal South Station | 1 transfer | |
| Sunday, June 21 | |||||
+ FlixBus · FlixBus | 3:25 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 25h15 | 4:40 AM Boston, Bus Terminal South Station | 2 transfers | |
· | 7:10 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 22h00 | 5:10 AM Boston, Bus Terminal South Station | 1 transfer | |
FlixBus · FlixBus | 12:15 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 21h10 | 9:25 AM Boston, Bus Terminal South Station | 1 transfer | |
Find all the dates and times for this journey
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Greenville, SC to Boston, MA run on average 4 times per day, taking around 20h 19m. Cheap bus tickets for this journey start at $214 (€175) if you book in advance.
The earliest bus runs at 01:30, the last at 22:00. The fastest bus covers the 800 miles (1289 km) distance in 20h 50m.
Distance 800 miles (1289 km) |
Average bus duration 20h 19m |
Cheapest ticket price $214 (€175) |
Buses per day 4 |
Fastest bus 20h 50m |
First bus 1:30 AM |
Last bus 10:00 PM |
Cheapest Month Nov |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Apr - Jun |
Discover the best of Boston — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Boston trip today.
One of the largest art museums in the United States, known for its encyclopedic collection spanning ancient to contemporary works.
A distinctive Venetian-style museum with major European, Asian, and American art, famous for its intimate courtyard and historic 1990 art theft.
A family-friendly science museum with hands-on exhibits, a planetarium, and broad appeal for visitors interested in technology and natural science.
Boston’s signature walking route linking many of the city’s most important historic sites, ideal for first-time visitors.
The oldest public park in the United States, serving as a central green space and gateway to the Freedom Trail.
A picturesque landscaped garden known for its lagoon, bridges, and swan boats, especially photogenic in spring and summer.
A creamy soup of clams, potatoes, and onions that is one of Boston’s signature comfort foods and a classic of New England cooking.
Sweet lobster meat served in a buttered split-top roll, often dressed lightly with mayo or warm butter. It is a beloved Boston-area seafood staple.
Slow-cooked beans traditionally baked with molasses and salt pork, tied to the city’s old nickname, 'Beantown,' and its colonial food history.
Highly regarded restaurant in Cambridge near Boston, known for refined Eastern Mediterranean cooking, excellent ingredients, and a warm upscale atmosphere.
Iconic North End bakery best known for cannoli and other Italian pastries, popular with both locals and visitors seeking a classic Boston sweet stop.
Small, celebrated North End seafood spot known for lobster rolls, oysters, and a lively atmosphere. A longtime favorite for classic Boston seafood.
Boston is pricey by U.S. standards, especially for hotels and dining, though casual food and transit are manageable.
Tip 18-20% in restaurants, 20%+ for great service. USD 1-2 per drink at bars, round up taxis, and tip hotel staff USD 2-5.
Find answers to the most common questions about traveling from Greenville, SC to Boston, MA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Boston, MA, this guide helps you travel smarter and with confidence.

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