The cheapest and fastest buses from Greenville, SC to Boston, MA
Cheapest price
$220
Average price
$220
Fastest journey
21 h 45 m
Average duration
21 h 45 m
Buses per day
1
Distance
1289 km
The best way to find a cheap bus ticket from Greenville, SC to Boston, MA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Boston, MA will cost around $220 if you buy it on the day, but the cheapest tickets can be found for only $220.
Of the 1 buses that leave Greenville, SC for Boston, MA on Mon, Mar 23, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Mar 23 the direct buses cover the 1289 km distance in an average of 21 h 45 m but if you time it right, some buses will get you there in just 21 h 45 m .
On Mon, Mar 23 the slowest buses will take 21 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for Greenville, SC to Boston, MA
Omio recommends booking the bus as it is the most popular option from Greenville, SC to Boston, MA among Omio's users. If you are prioritising price take the bus with prices starting from $129. For those with little time consider booking a flight which can get you there in 4h 23m. The ticket price range depends on the travel mode: a bus costs an average of $129, and a flight costs an average of $283.
Distance: 800 miles (1289 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$156 Average price Cheapest | $292 Average price | $334 Average price |
20h 49m Average total duration 20h 19m Onboard + 30m Additional time* | 20h 7m Average total duration 19h 37m Onboard + 30m Additional time* | 7h 23m Average total duration Fastest 4h 23m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Greenville, SC to Boston, MA bus times
The table below shows live departures for Greenville, SC to Boston, MA buses for today, Sunday, March 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:15 PM Greenville, SC | 22h55 | 8:10 PM Boston, MA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Greenville, SC to Boston, MA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Mar 29
Why should you book Greenville, SC to Boston, MA buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Greenville, SC to Boston, MA.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Greenville, SC to Boston, MA.
Journey information
Overview: Bus from Greenville, SC to Boston, MA
Buses from Greenville, SC to Boston, MA run on average 4 times per day, taking around 20h 19m. Cheap bus tickets for this journey start at $129 (€105) if you book in advance.
The earliest bus runs at 01:30, the last at 22:15. The fastest bus covers the 800 miles (1289 km) distance in 20h 50m.
Distance 800 miles (1289 km) |
Average bus duration 20h 19m |
Cheapest ticket price $129 (€105) |
Buses per day 4 |
Fastest bus 20h 50m |
First bus 01:30 |
Last bus 22:15 |
Bus providers: FlixBus from Greenville, SC to Boston, MAYou can travel by bus between Greenville, SC to Boston, MA with FlixBus for as low as $129 (€105). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Greenville, SC to Boston, MA
Find answers to the most common questions about traveling from Greenville, SC to Boston, MA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Boston, MA, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Best sights: Freedom Trail, a 2.5-mile-long path through downtown Boston that passes by 16 significant historical sites
- Fenway Park, the iconic baseball stadium and home of the Boston Red Sox
- Museum of Fine Arts, one of the largest art museums in the United States with an extensive collection of artworks
- Boston Common, the oldest public park in the United States offering green space and historical landmarks
- New England Aquarium, a popular attraction featuring a wide variety of marine life and interactive exhibits.
- Things to do: Explore the historic streets of Beacon Hill, known for its charming cobblestone streets and Federal-style rowhouses
- Take a scenic walk along the Charles River Esplanade, offering beautiful views of the Boston skyline
- Visit the Boston Public Library, a stunning architectural landmark with impressive collections and exhibits
- Enjoy a guided tour of the historic USS Constitution, the world's oldest commissioned naval vessel still afloat
- Discover the vibrant atmosphere of Quincy Market, with its diverse food stalls and unique shops.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Greenville, SC to Boston, MA
Most popular bus connections from Greenville, SC
More options for your journey from Greenville, SC to Boston, MA
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