- Must visit
Walker Art Center
Major contemporary art museum with acclaimed architecture, rotating exhibitions, and one of the top collections in the region.
The best way to find a cheap bus ticket from Greenville, SC to Minneapolis, MN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Minneapolis, MN will cost around $344 if you buy it on the day, but the cheapest tickets can be found for only $271.
On Wed, Nov 04, we found 2 buses from Greenville, SC to Minneapolis, MN, including 2 direct services.
On Wed, Nov 04 the direct buses cover the 1456 km distance in an average of 1 d 10 h 35 m but if you time it right, some buses will get you there in just 1 d 5 h 55 m .
On Wed, Nov 04 the slowest buses will take 1 d 15 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Greenville, SC to Minneapolis, MN run on average 3 times per day, taking around 28h 58m. Cheap bus tickets for this journey start at $102 if you book in advance.
The earliest bus runs at 00:15, the last at 22:00. The fastest bus covers the 904 miles (1456 km) distance in 26h 35m.
Distance 904 miles (1456 km) |
Average bus duration 28h 58m |
Cheapest ticket price $102 |
Buses per day 3 |
Fastest bus 26h 35m |
First bus 12:15 AM |
Last bus 10:00 PM |
Cheapest Month Sep |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Jan - Mar |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Greenville, SC to Minneapolis, MN.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:40AM | Arrival Time 12:30PM | Duration 35h50 | Departure days Sun | Cheapest price $148 |
Operator Greyhound | Departure Time 01:20PM | Arrival Time 06:15PM | Duration 29h55 | Departure days Tue, Thu | Cheapest price $124 |
Operator Greyhound | Departure Time 02:45PM | Arrival Time 12:15AM | Duration 34h30 | Departure days Tue, Thu | Cheapest price $135 |
Operator Greyhound | Departure Time 06:20PM | Arrival Time 12:15AM | Duration 29h55 | Departure days Wed | Cheapest price $271 |
Operator Greyhound | Departure Time 06:45PM | Arrival Time 05:20AM | Duration 34h35 | Departure days Fri, Sun | Cheapest price $282 |
Operator Greyhound | Departure Time 08:15PM | Arrival Time 11:30AM | Duration 39h15 | Departure days Wed | Cheapest price $417 |
Operator Greyhound | Departure Time 08:20PM | Arrival Time 06:15AM | Duration 34h55 | Departure days Tue, Thu | Cheapest price $124 |
Operator FlixBus | Departure Time 11:40PM | Arrival Time 11:30AM | Duration 35h50 | Departure days Mon, Sat | Cheapest price $221 |
Operator Greyhound | Departure Time 11:40PM | Arrival Time 11:30AM | Duration 35h50 | Departure days Fri | Cheapest price $157 |
The table below shows live departures for Greenville, SC to Minneapolis, MN buses for today, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · · | 8:20 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 34h55 | 6:15 AM Minneapolis, 5th St Transit Center (Ramp B), MN | 3 transfers | |
| Wednesday, November 4 | |||||
![]() | 6:20 PM Greenville, SC | 29h55 | 12:15 AM Minneapolis, MN | 0 transfersDirect | |
![]() | 8:15 PM Greenville, SC | 39h15 | 11:30 AM Minneapolis, MN | 0 transfersDirect | |
This is the last bus of the day. | |||||
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Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Minneapolis, MN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Minneapolis, MN trip today.
Major contemporary art museum with acclaimed architecture, rotating exhibitions, and one of the top collections in the region.
Smithsonian-affiliated history museum inside Mill City Museum, exploring Minneapolis industry, flour, and riverfront development.
Leading fine arts museum with global collections, period rooms, and strong Native, Asian, and modern works.
Famous urban sculpture garden with the Spoonbridge and Cherry, linking art, skyline views, and easy walking paths.
Lakeside park with beaches, trails, and classic Minneapolis scenery; ideal for walks, biking, and sunset views.
Historic riverfront district with cobbled character, trails, bridges, and excellent views of the Mississippi and downtown.
The iconic Minnesota hot dish: ground beef, vegetables, cream soup, and tater tots baked until crisp. A beloved Upper Midwest comfort food common at family gatherings.
A Scandinavian potato flatbread central to Minnesota holiday tables. It reflects the region’s strong Nordic heritage and is often served with butter or sugar.
Minnesota’s famous wild rice soup combines nutty native wild rice with cream, vegetables, and often chicken. It highlights an ingredient deeply tied to the state.
Acclaimed fine-dining destination showcasing Minnesota ingredients with refined tasting menus. Elegant, polished, and nationally respected.
Long-running restaurant known for excellent walleye and classic supper-club style. Comfortable setting near Minnehaha Falls.
Legendary South Minneapolis tavern famous for the original Juicy Lucy. Casual, lively, and essential for a classic local burger experience.
Moderate for a major US city. Hotels, dining, and attractions are mid-priced, while transit is affordable and budget eats are easy to find.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis, and spare change or $1 at cafes.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Minneapolis, MN.
Find answers to the most common questions about traveling from Greenville, SC to Minneapolis, MN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Minneapolis, MN, this guide helps you travel smarter and with confidence.

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