- Must visit
Minneapolis Institute of Art
Major fine arts museum with a globally significant collection spanning ancient to contemporary works. A top cultural stop in the city.
Cheapest price
$141
Average price
$152
Fastest journey
1 d 5 h 55 m
Average duration
1 d 9 h 5 m
Buses per day
3
Distance
1456 km
The best way to find a cheap bus ticket from Greenville, SC to Minneapolis, MN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Minneapolis, MN will cost around $152 if you buy it on the day, but the cheapest tickets can be found for only $141.
It's difficult to get from Greenville, SC to Minneapolis, MN without transferring at least 2 times.
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· · Omio recommends booking the train as it is the most popular option from Greenville, SC to Minneapolis, MN among Omio's users. If you are prioritising price take the bus with prices starting from $138. For those with little time consider booking a flight which can get you there in 6h 35m. The ticket price range depends on the travel mode: a bus costs an average of $138, and a flight costs an average of $182.
Distance: 904 miles (1456 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$264 Average price Cheapest | $494 Average price | $503 Average price | $231 Average price (fuel + tolls) |
35h 55m Average total duration 35h 25m Onboard + 30m Additional time* | 37h 27m Average total duration 36h 57m Onboard + 30m Additional time* | 9h 35m Average total duration Fastest 6h 35m Onboard + 3h 0m Additional time* | 16h 54m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greenville, SC to Minneapolis, MN:
A bus is $230 (€188) less than a train for this route with tickets for a train from Greenville, SC to Minneapolis, MN costing on average $494 (€404).
A bus is $240 (€196) less than a flight for this route with tickets for a flight from Greenville, SC to Minneapolis, MN costing on average $503 (€412).
Other travel options to Minneapolis, MN take longer:
Bus takes on average 35h 25m.
Train takes on average 36h 57m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:20PM | Arrival Time 06:15PM | Duration 29h55 | Departure days Everyday | Cheapest price $144 |
Operator Greyhound | Departure Time 02:45PM | Arrival Time 12:05AM | Duration 34h20 | Departure days Everyday | Cheapest price $141 |
Operator Greyhound | Departure Time 08:20PM | Arrival Time 06:20AM | Duration 35h00 | Departure days Everyday | Cheapest price $143 |
The table below shows live departures for Greenville, SC to Minneapolis, MN buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · | 8:20 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 35h00 | 6:20 AM Minneapolis, 5th St Transit Center (Ramp B), MN | 2 transfers | |
| Sunday, June 21 | |||||
FlixBus+ + FlixBus | 1:20 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 29h55 | 6:15 PM Minneapolis, 5th St Transit Center (Ramp B), MN | 2 transfers | |
· · | 2:45 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 34h20 | 12:05 AM Minneapolis, 5th St Transit Center (Ramp B), MN | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Greenville, SC to Minneapolis, MN run on average 3 times per day, taking around 35h 25m. Cheap bus tickets for this journey start at $138 (€113) if you book in advance.
The earliest bus runs at 00:15, the last at 22:00. The fastest bus covers the 904 miles (1456 km) distance in 29h 55m.
Distance 904 miles (1456 km) |
Average bus duration 35h 25m |
Cheapest ticket price $138 (€113) |
Buses per day 3 |
Fastest bus 29h 55m |
First bus 12:15 AM |
Last bus 10:00 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jul - Sep |
Discover the best of Minneapolis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Minneapolis trip today.
Major fine arts museum with a globally significant collection spanning ancient to contemporary works. A top cultural stop in the city.
Leading contemporary art museum known for modern exhibitions, design, film, and performance. Closely linked with the Minneapolis Sculpture Garden.
Museum inside the ruins of the Washburn A Mill, explaining Minneapolis flour-milling history and the growth of the riverfront.
Large riverside park centered on Minnehaha Falls, with trails, limestone scenery, and one of the city's most photographed spots.
Highly popular outdoor art park beside the Walker Art Center, home to the famous Spoonbridge and Cherry sculpture.
Beloved urban lake with walking and biking paths, beaches, and skyline views. A favorite local outdoor area in warm weather.
A Minneapolis burger specialty with molten cheese sealed inside the beef patty, famously associated with South Minneapolis taverns.
A classic Minnesota freshwater fish, often pan-fried or battered, celebrated across the Twin Cities for its mild flavor.
A beloved Upper Midwest casserole of ground meat, vegetables, creamy sauce, and tater tots, common at family tables and potlucks.
Acclaimed restaurant focused on Indigenous North American ingredients and techniques, offering one of the city's most distinctive dining experiences.
Popular downtown restaurant known for hearty brunches, comfort food, and a lively, long-running Minneapolis personality.
Legendary no-frills South Minneapolis bar famous for the original-style Jucy Lucy and a classic local tavern atmosphere.
Prices are moderate for a major U.S. city. Casual food is reasonable, but hotels and fine dining can be pricey during peak periods.
Tip 18-20% at restaurants; 20%+ for great service. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
Find answers to the most common questions about traveling from Greenville, SC to Minneapolis, MN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Minneapolis, MN, this guide helps you travel smarter and with confidence.

Most Greenville, SC to Minneapolis, MN buses use the Greenville, Woodruff Rd ("Raceway" gas station) to station pair. Use this guide to compare Greenville, SC and Minneapolis, MN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need