- Must visit
Cleveland Museum Of Art
Major encyclopedic art museum in University Circle, known for its outstanding collections spanning Asia, Europe, Africa, and the Americas. A top cultural stop in Cleveland.
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The cheapest and fastest buses from Greenville, SC to Cleveland, OH
Showing times and prices for Jun 22
Cheapest price
$118
Average price
$138
Fastest journey
19 h 40 m
Average duration
22 h 23 m
Buses per day
3
Distance
742 km
Cheap tickets
The best way to find a cheap bus ticket from Greenville, SC to Cleveland, OH is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Cleveland, OH will cost around $138 if you buy it on the day, but the cheapest tickets can be found for only $118.
Fast buses
It's difficult to get from Greenville, SC to Cleveland, OH without transferring at least 2 times.
FlixBus+
+FlixBus9:35 PM22h40Greenville, Woodruff Rd ("Raceway" gas station), SC8:15 PMCleveland, Chester Ave At the Greyhound Station (South Side)$1181One-way2 transfers- · · 3:25 AM24h50Greenville, Woodruff Rd ("Raceway" gas station), SC4:15 AMCleveland, Chester Ave At the Greyhound Station (South Side)$1431One-way2 transfers
- · · 2:45 PM19h40Greenville, Woodruff Rd ("Raceway" gas station), SC10:25 AMCleveland, Chester Ave At the Greyhound Station (South Side)$1521One-way2 transfers
- · · 2:45 PM19h40Greenville, Woodruff Rd ("Raceway" gas station), SC10:25 AMCleveland, Chester Ave At the Greyhound Station (South Side)$1521One-way2 transfers
- FlixBus++FlixBus9:35 PM22h40Greenville, Woodruff Rd ("Raceway" gas station), SC8:15 PMCleveland, Chester Ave At the Greyhound Station (South Side)$1181One-way2 transfers
- · · 3:25 AM24h50Greenville, Woodruff Rd ("Raceway" gas station), SC4:15 AMCleveland, Chester Ave At the Greyhound Station (South Side)$1431One-way2 transfers
Travel Information
Compare bus, train, and flight for Greenville, SC to Cleveland, OH
Omio recommends booking the flight as it is the most popular option from Greenville, SC to Cleveland, OH among Omio's users. If you are prioritising price take the bus with prices starting from $175. For those with little time consider booking a flight which can get you there in 3h 29m. The ticket price range depends on the travel mode: a bus costs an average of $175, and a flight costs an average of $429.
Distance: 461 miles (742 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$191 Average price Cheapest | $429 Average price | $401 Average price | $118 Average price (fuel + tolls) |
21h 30m Average total duration 21h 0m Onboard + 30m Additional time* | 6h 29m Average total duration Fastest 3h 29m Onboard + 3h 0m Additional time* | 25h 0m Average total duration 24h 30m Onboard + 30m Additional time* | 9h 20m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Greenville, SC to Cleveland, OH is a bus with an average price of $191 (€156).
This is compared to other travel options from Greenville, SC to Cleveland, OH:
A bus is $210 (€172) less than a train for this route with tickets for a train from Greenville, SC to Cleveland, OH costing on average $401 (€328).
A bus is $238 (€195) less than a flight for this route with tickets for a flight from Greenville, SC to Cleveland, OH costing on average $429 (€351).
The fastest way to travel from Greenville, SC to Cleveland, OH is by flight with an average journey time of 3h 29m.
Other travel options to Cleveland, OH take longer:
Bus takes on average 21h 0m.
Train takes on average 24h 30m.
It's helpful to compare your options as there are 3 ways to travel between Greenville, SC and Cleveland, OH including taking a bus, train, and flight.
We recommend using the flight as it is the most popular way to get from Greenville, SC to Cleveland, OH among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Greenville, SC to Cleveland, OH Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:25AM | Arrival Time 04:15AM | Duration 24h50 | Departure days Mon | Cheapest price $143 |
Operator Greyhound | Departure Time 02:45PM | Arrival Time 10:25AM | Duration 19h40 | Departure days Mon | Cheapest price $152 |
Operator Greyhound | Departure Time 06:45PM | Arrival Time 02:30PM | Duration 19h45 | Departure days Tue | Cheapest price $207 |
Operator Greyhound | Departure Time 09:35PM | Arrival Time 08:15PM | Duration 22h40 | Departure days Mon | Cheapest price $118 |
Live departures
Greenville, SC to Cleveland, OH bus times
The table below shows live departures for Greenville, SC to Cleveland, OH buses for tomorrow, Monday, June 22. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · · | 3:25 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 24h50 | 4:15 AM Cleveland, Chester Ave At the Greyhound Station (South Side) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Greenville, SC to Cleveland, OH by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Greenville, SC to Cleveland, OH
USAUSA
Buses from Greenville, SC to Cleveland, OH run on average 3 times per day, taking around 21h 0m. Cheap bus tickets for this journey start at $175 (€143) if you book in advance.
The earliest bus runs at 02:35, the last at 22:00. The fastest bus covers the 461 miles (742 km) distance in 19h 45m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 461 miles (742 km) |
Average bus duration 21h 0m |
Cheapest ticket price $175 (€143) |
Buses per day 3 |
Fastest bus 19h 45m |
First bus 2:35 AM |
Last bus 10:00 PM |
Cheapest Month Apr |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Oct - Dec |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Complete guide to Cleveland
Things to do in Cleveland
Discover the best of Cleveland — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Cleveland trip today.
- Must visit
Rock And Roll Hall Of Fame
Iconic lakefront museum celebrating the history and influence of rock music through artifacts, immersive exhibits, and rotating major shows. One of Cleveland's signature attractions.
- Recommended
Museum Of Contemporary Art Cleveland
Striking contemporary art museum known for its angular building and changing exhibitions featuring emerging and established artists. Popular with visitors seeking modern culture.
- Must visit
Public Square
Central downtown square recently redesigned as a civic gathering space. A practical starting point for seeing major buildings, events, and everyday city life.
- Must visit
University Circle
Cleveland's premier cultural district, home to major museums, gardens, and historic institutions. Ideal for visitors wanting a dense concentration of top sights.
- Must visit
Edgewater Park
Lakefront park with beach access, skyline views, trails, and sunset photography spots. Especially popular in warm weather and widely shared on social media.
Polish Boy
Cleveland’s signature sandwich: a kielbasa sausage topped with fries, barbecue sauce, and coleslaw on a bun. It is a local staple closely tied to the city’s East Side food culture.
- Vegetarian
Pierogi
Dumplings filled with potato, cheese, sauerkraut, or meat, reflecting Cleveland’s strong Polish and Central European heritage. They are a beloved comfort food across the city.
Corned Beef Sandwich
A classic deli sandwich piled high with tender corned beef, especially associated with Cleveland’s old-school Jewish delis. It is one of the city’s most famous hearty lunches.
Pier W
A long-established fine dining seafood restaurant with Lake Erie views. Known for polished service, fresh fish, and a special-occasion atmosphere.
Rowley Inn
A well-liked neighborhood tavern near Tremont, known for comfort food, pierogi, and local favorites. Relaxed, historic, and distinctly Cleveland.
Slyman's Restaurant
An iconic Cleveland deli famous for towering corned beef sandwiches. Casual, busy, and one of the city’s best-known lunch institutions.
United States Dollar
Moderate by U.S. standards. Hotels vary by season, while casual dining, coffee, and local transport are fairly affordable.
Average meal costs
- Budget
- USD 10-18 for fast food or a simple lunch.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 60-120+ per person at upscale restaurants.
- Coffee
- USD 3-6 for drip coffee or a latte.
Tipping culture
Tip 18-20% at restaurants; 20%+ for excellent service. Tip bartenders USD 1-2 per drink, taxis 10-15%, hotel staff USD 1-5, and round up for cafes.
FAQs: Bus from Greenville, SC to Cleveland, OH
Find answers to the most common questions about traveling from Greenville, SC to Cleveland, OH by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Cleveland, OH, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Greenville, SC to Cleveland, OH can start from as little as $175 (€143) when you book in advance. The average bus ticket price for Greenville, SC to Cleveland, OH is $191 (€156) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Greenville, SC to Cleveland, OH is 19h 45m to travel the 461 miles (742 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Greenville, SC to Cleveland, OH leaves at 2:35 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Greenville, SC to Cleveland, OH leaves at 10:00 PM.
A trip to Cleveland, OH from Greenville, SC is worth doing but not as a day trip with a journey time of 19h 45m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Greenville, SC to Cleveland, OH is April.
It's helpful to compare your options as there are 3 ways to travel between Greenville, SC and Cleveland, OH including taking a bus, train, and flight.
No, the bus from Greenville, SC to Cleveland, OH has no accessibility options.
No, there are no bathrooms on board the bus from Greenville, SC to Cleveland, OH.
No, bikes are not allowed on board the bus from Greenville, SC to Cleveland, OH.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Greenville, SC to Cleveland, OH.
No, luggage for the bus from Greenville, SC to Cleveland, OH needs to be booked in addition.
No, there are no additional luggage options for the bus from Greenville, SC to Cleveland, OH.
Unfortunately, pets are not allowed on the bus from Greenville, SC to Cleveland, OH.
No, there are no USB plugs on board the bus from Greenville, SC to Cleveland, OH.
No, there is no WiFi on board the bus from Greenville, SC to Cleveland, OH.
Since neither Greenville, SC nor Cleveland, OH are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Greenville, SC to Cleveland, OH among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Cleveland, OH, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and popular attractions. Avoid poorly lit or isolated neighborhoods at night. Common scams include fake ticket sellers near sports venues and overcharging by unlicensed taxi or rideshare drivers. Staying alert and using official transportation options enhances safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Greenville, SC to Cleveland, OH
Most Greenville, SC to Cleveland, OH buses use the Greenville, Woodruff Rd ("Raceway" gas station) to Cleveland, Chester Ave At the Greyhound Station (South Side) station pair. Use this guide to compare Greenville, SC and Cleveland, OH bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Greenville
Arrival bus stations in Cleveland
Greenville, Woodruff Rd ("Raceway" gas station)
Cleveland, Chester Ave At the Greyhound Station (South Side)
City-centre transport
Getting to Cleveland, Chester Ave At the Greyhound Station (South Side) from Cleveland city centre
BusHl · 15m · $4 · every ~10 min
Hl · 16m · $4 · every ~10 min
Most popular bus connections from Greenville, SC
More options for your journey from Greenville, SC to Cleveland, OH
Here are some other resources that might have the information you need
Most popular buses to and from Cleveland, OH and Greenville, SC
Most popular bus connections to Cleveland, OH
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