- Must visit
Cleveland Museum of Art
World-class art museum famed for encyclopedic collections, free general admission, and standout holdings from ancient to contemporary art.
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The cheapest and fastest buses from Greenville, SC to Cleveland, OH
Showing times, prices and bookable tickets for Nov 04
- Cheapest price on Nov 04
- $101
- Average ticket price on Nov 04
- $105
- Fastest journey on Nov 04
- 19 h 40 m
- Average journey duration on Nov 04
- 22 h 23 m
- Buses on Nov 04
- 3
- Distance
- 742 km
Cheap tickets
The best way to find a cheap bus ticket from Greenville, SC to Cleveland, OH is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Cleveland, OH will cost around $105 if you buy it on the day, but the cheapest tickets can be found for only $101.
Fast buses
It's difficult to get from Greenville, SC to Cleveland, OH without transferring at least 2 times.
FlixBus+
+FlixBus9:35 PM 22h40 Greenville, Woodruff Rd ("Raceway" gas station), SC 8:15 PM Cleveland, Chester Ave At the Greyhound Station (South Side) $101 1 One-way 2 transfers- · ·
2:45 PM 19h40 Greenville, Woodruff Rd ("Raceway" gas station), SC 10:25 AM Cleveland, Chester Ave At the Greyhound Station (South Side) $102 1 One-way 2 transfers - · ·
3:25 AM 24h50 Greenville, Woodruff Rd ("Raceway" gas station), SC 4:15 AM Cleveland, Chester Ave At the Greyhound Station (South Side) $112 1 One-way 2 transfers
- · ·
2:45 PM 19h40 Greenville, Woodruff Rd ("Raceway" gas station), SC 10:25 AM Cleveland, Chester Ave At the Greyhound Station (South Side) $102 1 One-way 2 transfers - FlixBus++FlixBus
9:35 PM 22h40 Greenville, Woodruff Rd ("Raceway" gas station), SC 8:15 PM Cleveland, Chester Ave At the Greyhound Station (South Side) $101 1 One-way 2 transfers - · ·
3:25 AM 24h50 Greenville, Woodruff Rd ("Raceway" gas station), SC 4:15 AM Cleveland, Chester Ave At the Greyhound Station (South Side) $112 1 One-way 2 transfers
Journey information
Overview: Bus from Greenville, SC to Cleveland, OH
USAUSA
Buses from Greenville, SC to Cleveland, OH run on average 3 times per day, taking around 19h 40m. Cheap bus tickets for this journey start at $80 (€67) if you book in advance.
The earliest bus runs at 02:35, the last at 22:00. The fastest bus covers the 461 miles (742 km) distance in 17h 20m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Plan this route
Journey facts
- Distance461 miles (742 km)
- Average bus duration19h 40m
- Cheapest ticket price$80 (€67)
- Buses per day3
- Fastest bus17h 20m
- First bus2:35 AM
- Last bus10:00 PM
- Cheapest MonthAug
- Cheapest DayWed
- High SeasonJul - Sep
- Low SeasonOct - Dec
Understand & plan this route
Book with confidence
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Frequently asked questions about your Greenville, SC to Cleveland, OH trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Greenville, SC to Cleveland, OH.
Cheap bus tickets from Greenville, SC to Cleveland, OH can start from as little as $80 (€67) when you book in advance. The average bus ticket price for Greenville, SC to Cleveland, OH is $117 (€99) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from Greenville, SC to Cleveland, OH leaves at 2:35 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Greenville, SC to Cleveland, OH leaves at 10:00 PM.
There are 3 buses a day from Greenville, SC to Cleveland, OH which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
Greenville, SC to Cleveland, OH Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:25AM | Arrival Time 04:15AM | Duration 24h50 | Departure days Mon, Wed | Cheapest price $112 |
Operator Greyhound | Departure Time 02:45PM | Arrival Time 10:25AM | Duration 19h40 | Departure days Mon, Wed | Cheapest price $95 |
Operator Greyhound | Departure Time 06:45PM | Arrival Time 02:30PM | Duration 19h45 | Departure days Tue | Cheapest price $202 |
Operator Greyhound | Departure Time 09:35PM | Arrival Time 08:15PM | Duration 22h40 | Departure days Mon, Wed | Cheapest price $96 |
Live departures
Greenville, SC to Cleveland, OH bus times
The table below shows live departures for Greenville, SC to Cleveland, OH buses for tomorrow, Wednesday, November 4. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · · | 3:25 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 24h50 | 4:15 AM Cleveland, Chester Ave At the Greyhound Station (South Side) | 2 transfers | |
| · · | 2:45 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 19h40 | 10:25 AM Cleveland, Chester Ave At the Greyhound Station (South Side) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Greenville, SC to Cleveland, OH buses with Omio?
Greyhound as well as FlixBus offer buses services from Greenville, SC to Cleveland, OH.
Omio is an official ticket reseller for all your travel options from Greenville, SC to Cleveland, OH.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Greenville, SC to Cleveland, OH.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Greenville, SC to Cleveland, OH.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Greenville, SC to Cleveland, OH.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Greenville, SC to Cleveland, OH.
Bus companies
Bus companies from Greenville, SC to Cleveland, OH
Buses from Greenville, SC to Cleveland, OH with Greyhound and FlixBus. Overnight buses available on this route with Greyhound and FlixBus. Use the details below to compare onboard facilities.
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
22h 19m
Cheapest FlixBus Price
$100 (€84)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
17h 20m
Cheapest Greyhound Price
$80 (€67)
Greyhound frequency
3 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Companies, tickets, and onboard amenities between Greenville, SC and Cleveland, OH
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from Greenville, SC to Cleveland, OH, you can count on Greyhound, FlixBus for the best way to get you to Cleveland, OH. You can also check all possible bus companies who offer a service between Greenville, SC and Cleveland, OH and compare the amenities they offer before buying a bus ticket.
Yes, there are bathrooms on board the bus from Greenville, SC to Cleveland, OH for bus company Greyhound, FlixBus.
Yes, the following accessibility options are available when taking the bus from Greenville, SC to Cleveland, OH:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from Greenville, SC to Cleveland, OH depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Yes, there is food available to purchase on board the bus from Greenville, SC to Cleveland, OH.
Yes, the following luggage options are included when booking a bus ticket from Greenville, SC to Cleveland, OH:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Greenville, SC to Cleveland, OH:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Greenville, SC to Cleveland, OH. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Greenville, SC to Cleveland, OH with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Greenville, SC to Cleveland, OH with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Greenville, SC to Cleveland, OH with the following bus company: Greyhound, FlixBus.
Complete guide to Cleveland, OH
Things to do in Cleveland, OH
Discover the best of Cleveland, OH — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Cleveland, OH trip today.
- Must visit
Rock and Roll Hall of Fame
Major music museum celebrating rock history with iconic artifacts, immersive exhibits, and strong appeal for first-time visitors.
- Recommended
Great Lakes Science Center
Excellent science museum with hands-on exhibits, a planetarium, and family-friendly learning in a restored historic mansion setting.
- Must visit
Ohio City
Historic neighborhood known for walkable streets, breweries, galleries, and one of the city’s most local-feeling main corridors.
- Must visit
Edgewater Park
Flagship urban park with lakefront trails, beaches, gardens, and broad recreation space close to downtown.
- Must visit
University Circle
Elegant cultural district anchored by museums, gardens, and classic architecture, ideal for a full day of walking and sightseeing.
Polish Boy
A Cleveland staple of kielbasa, French fries, barbecue sauce, and slaw stuffed in a bun. It reflects the city's Eastern European and blue-collar food traditions.
Stuffed Cabbage
Hearty Slovak-style stuffed cabbage rolls baked in tomato sauce. They are traditional in many Cleveland immigrant families and church festival menus.
- Vegetarian
Potato Pancakes
Crisp potato pancakes often served with applesauce or sour cream. They are closely tied to Cleveland's strong Central and Eastern European heritage.
Slyman's Restaurant
Beloved deli famous for towering corned beef sandwiches. Casual, no-frills, and widely considered a Cleveland institution.
Great Lakes Brewing Company
Historic Ohio City brewpub known for Cleveland beer culture, sausages, pretzels, and hearty pub fare in a lively, landmark setting.
The Black Pig
Refined farm-to-table restaurant in Ohio City serving seasonal American dishes with polished service and a warm neighborhood atmosphere.
United States dollar ($)
Moderate for U.S. city travel: hotels and dining are usually cheaper than New York or Chicago, while transit and attractions are generally manageable for visitors.
Average meal costs
- Budget
- $10-15 for fast food or casual spots.
- Mid-range
- $20-35 per person for a restaurant meal.
- Fine dining
- $60+ per person at upscale restaurants.
- Coffee
- $3-5 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or coffee in cafes if service is good.
Plan your visit to Cleveland, OH
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Cleveland, OH.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Cleveland, OH, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and popular attractions. Avoid poorly lit or isolated neighborhoods at night. Common scams include fake ticket sellers near sports venues and overcharging by unlicensed taxi or rideshare drivers. Staying alert and using official transportation options enhances safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from Greenville, SC to Cleveland, OH
Find answers to the most common questions about traveling from Greenville, SC to Cleveland, OH by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Cleveland, OH, this guide helps you travel smarter and with confidence.
It's helpful to compare your options as there are 3 ways to travel between Greenville, SC and Cleveland, OH including taking a bus, train, and flight.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Most popular bus connections from Greenville, SC
Most popular buses to and from Cleveland, OH and Greenville, SC
Most popular bus connections to Cleveland, OH
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