- Must visit
Cleveland Museum of Art
World-class art museum famed for encyclopedic collections, free general admission, and standout holdings from ancient to contemporary art.
Cheapest price
$97
Average price
$110
Fastest journey
19 h 40 m
Average duration
22 h 25 m
Buses per day
3
Distance
742 km
The best way to find a cheap bus ticket from Greenville, SC to Cleveland, OH is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Cleveland, OH will cost around $110 if you buy it on the day, but the cheapest tickets can be found for only $97.
It's difficult to get from Greenville, SC to Cleveland, OH without transferring at least 2 times.
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· · Omio recommends booking the flight as it is the most popular option from Greenville, SC to Cleveland, OH among Omio's users. If you are prioritising price take the bus with prices starting from $176. For those with little time consider booking a flight which can get you there in 3h 29m. The ticket price range depends on the travel mode: a bus costs an average of $176, and a flight costs an average of $432.
Distance: 461 miles (742 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$192 Average price Cheapest | $432 Average price | $403 Average price | $118 Average price (fuel + tolls) |
21h 30m Average total duration 21h 0m Onboard + 30m Additional time* | 6h 29m Average total duration Fastest 3h 29m Onboard + 3h 0m Additional time* | 25h 0m Average total duration 24h 30m Onboard + 30m Additional time* | 9h 20m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greenville, SC to Cleveland, OH:
A bus is $211 (€172) less than a train for this route with tickets for a train from Greenville, SC to Cleveland, OH costing on average $403 (€328).
A bus is $239 (€195) less than a flight for this route with tickets for a flight from Greenville, SC to Cleveland, OH costing on average $432 (€351).
Other travel options to Cleveland, OH take longer:
Bus takes on average 21h 0m.
Train takes on average 24h 30m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:00AM | Arrival Time 12:15AM | Duration 22h15 | Departure days Tue | Cheapest price $176 |
Operator Greyhound | Departure Time 03:25AM | Arrival Time 04:20AM | Duration 24h55 | Departure days Tue, Thu, Fri, Sat, Sun | Cheapest price $111 |
Operator Greyhound | Departure Time 02:45PM | Arrival Time 10:25AM | Duration 19h40 | Departure days Tue, Thu, Fri, Sat, Sun | Cheapest price $97 |
Operator Greyhound | Departure Time 09:35PM | Arrival Time 08:15PM | Duration 22h40 | Departure days Thu, Fri, Sat, Sun | Cheapest price $97 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 04:15AM | Duration 30h40 | Departure days Tue | Cheapest price $99 |
The table below shows live departures for Greenville, SC to Cleveland, OH buses for tomorrow, Thursday, August 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · | 3:25 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 24h55 | 4:20 AM Cleveland, Chester Ave At the Greyhound Station (South Side) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Greenville, SC to Cleveland, OH run on average 3 times per day, taking around 21h 0m. Cheap bus tickets for this journey start at $176 (€143) if you book in advance.
The earliest bus runs at 02:35, the last at 22:00. The fastest bus covers the 461 miles (742 km) distance in 19h 45m.
Distance 461 miles (742 km) |
Average bus duration 21h 0m |
Cheapest ticket price $176 (€143) |
Buses per day 3 |
Fastest bus 19h 45m |
First bus 2:35 AM |
Last bus 10:00 PM |
Cheapest Month Apr |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Oct - Dec |
Discover the best of Cleveland, OH — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Cleveland, OH trip today.
World-class art museum famed for encyclopedic collections, free general admission, and standout holdings from ancient to contemporary art.
Major music museum celebrating rock history with iconic artifacts, immersive exhibits, and strong appeal for first-time visitors.
Excellent science museum with hands-on exhibits, a planetarium, and family-friendly learning in a restored historic mansion setting.
Historic neighborhood known for walkable streets, breweries, galleries, and one of the city’s most local-feeling main corridors.
Flagship urban park with lakefront trails, beaches, gardens, and broad recreation space close to downtown.
Elegant cultural district anchored by museums, gardens, and classic architecture, ideal for a full day of walking and sightseeing.
A Cleveland staple of kielbasa, French fries, barbecue sauce, and slaw stuffed in a bun. It reflects the city's Eastern European and blue-collar food traditions.
Hearty Slovak-style stuffed cabbage rolls baked in tomato sauce. They are traditional in many Cleveland immigrant families and church festival menus.
Crisp potato pancakes often served with applesauce or sour cream. They are closely tied to Cleveland's strong Central and Eastern European heritage.
Beloved deli famous for towering corned beef sandwiches. Casual, no-frills, and widely considered a Cleveland institution.
Historic Ohio City brewpub known for Cleveland beer culture, sausages, pretzels, and hearty pub fare in a lively, landmark setting.
Refined farm-to-table restaurant in Ohio City serving seasonal American dishes with polished service and a warm neighborhood atmosphere.
Moderate for U.S. city travel: hotels and dining are usually cheaper than New York or Chicago, while transit and attractions are generally manageable for visitors.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or coffee in cafes if service is good.
Find answers to the most common questions about traveling from Greenville, SC to Cleveland, OH by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Cleveland, OH, this guide helps you travel smarter and with confidence.

Most Greenville, SC to Cleveland, OH buses use the Greenville, Woodruff Rd ("Raceway" gas station) to Cleveland, Chester Ave At the Greyhound Station (South Side) station pair. Use this guide to compare Greenville, SC and Cleveland, OH bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Greenville, Woodruff Rd ("Raceway" gas station) is 8 km from Greenville city centre. Public transport options include:
Greenville, Woodruff Rd ("Raceway" gas station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Limited dining options available in adjacent areas.
Wi-Fi is available at Greenville, Woodruff Rd ("Raceway" gas station). ATMs are available at Greenville, Woodruff Rd ("Raceway" gas station).
Ticket office support is available at Greenville, Woodruff Rd ("Raceway" gas station).
Available at Greenville, Woodruff Rd ("Raceway" gas station): Parking, Taxis, WC.
Accessibility facilities are available at Greenville, Woodruff Rd ("Raceway" gas station): Basic access available for persons with disabilities.
Cleveland, Chester Ave At the Greyhound Station (South Side) is 1 km from Cleveland city centre. Public transport options include:
Cleveland, Chester Ave At the Greyhound Station (South Side) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack bar available onsite.
Free WiFi available for passengers. ATMs are available at Cleveland, Chester Ave At the Greyhound Station (South Side).
Ticket office support is available at Cleveland, Chester Ave At the Greyhound Station (South Side).
Available at Cleveland, Chester Ave At the Greyhound Station (South Side): Parking, Taxis, WC.
Accessibility facilities are available at Cleveland, Chester Ave At the Greyhound Station (South Side): Station is wheelchair accessible.
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