The cheapest and fastest buses from Greenville, SC to San Diego, CA
Cheapest price
$171
Average price
$171
Fastest journey
2 d 11 h 35 m
Average duration
2 d 11 h 35 m
Buses per day
1
Distance
3206 km
The best way to find a cheap bus ticket from Greenville, SC to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to San Diego, CA will cost around $171 if you buy it on the day, but the cheapest tickets can be found for only $171.
Of the 1 buses that leave Greenville, SC for San Diego, CA on Fri, Nov 07, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Nov 07 the direct buses cover the 3206 km distance in an average of 2 d 11 h 35 m but if you time it right, some buses will get you there in just 2 d 11 h 35 m .
On Fri, Nov 07 the slowest buses will take 2 d 11 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus and flight for Greenville, SC to San Diego, CA
Omio recommends booking the bus as it is the most popular option from Greenville, SC to San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from €140. For those with little time consider booking a flight which can get you there in 8h 24m. The ticket price range depends on the travel mode: a bus costs an average of €140, and a flight costs an average of €163.
Distance: 1992 miles (3206 km)
Compare bus with
Most popular Bus | Flight |
|---|---|
€191 Average price Cheapest | €225 Average price |
52h 55m Average total duration 52h 25m Onboard + 30m Additional time* | 11h 24m Average total duration Fastest 8h 24m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
Live departures
Greenville, SC to San Diego, CA bus times
The table below shows live departures for Greenville, SC to San Diego, CA buses for tomorrow, Friday, November 7. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:55 PM Greenville, SC | 59h35 | 4:30 AM San Diego, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Greenville, SC to San Diego, CA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Nov 13
Journey information
Overview: Bus from Greenville, SC to San Diego, CA
Distance 1992 miles (3206 km) |
Average bus duration 52h 25m |
Cheapest ticket price $171 (€140) |
Buses per day 9 |
Fastest bus 54h 0m |
First bus 06:55 |
Last bus 22:00 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Greenville, SC to San Diego, CA start from as low as $171 (€140) if booked well in advance.
- Standard Fares: Typically, trains cost $234 (€191) depending on the train type and class.
Bus providers: Greyhound from Greenville, SC to San Diego, CAYou can travel by bus between Greenville, SC to San Diego, CA with Greyhound for as low as $171 (€140). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Greenville, SC to San Diego, CA
Find answers to the most common questions about traveling from Greenville, SC to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Balboa Park, a sprawling urban park with museums, gardens, and the San Diego Zoo
- USS Midway Museum, a historic naval aircraft carrier museum offering interactive exhibits and tours
- La Jolla Cove, a picturesque coastal area known for its stunning views and marine life
- Gaslamp Quarter, a lively historic district with Victorian architecture, dining, and entertainment options
- Coronado Beach, a beautiful sandy beach known for its gentle waves and iconic hotel.
- Explore the vibrant art scene at the Museum of Contemporary Art San Diego
- Enjoy a harbor cruise for stunning views of the skyline and naval ships
- Hike the scenic trails at Torrey Pines State Natural Reserve
- Visit the Birch Aquarium to learn about marine life and ocean conservation
- Experience the thrill of a whale watching tour off the coast.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Greenville, SC to San Diego, CA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Greenville, SC to San Diego, CA
Most popular bus connections from Greenville, SC
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