Greenville, SC to Chicago, IL bus

Fri, Feb 06
+ Add return
FlixBus
Costa Verde
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
FlixBus
Costa Verde
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

The cheapest and fastest buses from Greenville, SC to Chicago, IL

Showing times and prices for Feb 06

Cheapest price

$186

Average price

$186

Fastest journey

21 h 45 m

Average duration

21 h 45 m

Buses per day

1

Distance

903 km

Cheap tickets

The best way to find a cheap bus ticket from Greenville, SC to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Greenville, SC to Chicago, IL will cost around $186 if you buy it on the day, but the cheapest tickets can be found for only $186.

Fast buses

Of the 1 buses that leave Greenville, SC for Chicago, IL on Fri, Feb 06, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Fri, Feb 06 the direct buses cover the 903 km distance in an average of 21 h 45 m but if you time it right, some buses will get you there in just 21 h 45 m .

On Fri, Feb 06 the slowest buses will take 21 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus
06:45PM21h45
Greenville, SC
04:30PMChicago, IL
$1861One-way
0 transfers

Travel Information

Compare bus, train, and flight for Greenville, SC to Chicago, IL

Omio recommends booking the bus as it is the most popular option from Greenville, SC to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from €101. For those with little time consider booking a flight which can get you there in 4h 4m. The ticket price range depends on the travel mode: a bus costs an average of €101, and a flight costs an average of €268.

Distance: 561 miles (903 km)

Compare bus with

Most popular
Bus
Flight
Train

€117

Average price

Cheapest

€359

Average price

€195

Average price

19h 10m

Average total duration

18h 40m

Onboard

+

30m

Additional time*

7h 4m

Average total duration

Fastest

4h 4m

Onboard

+

3h 0m

Additional time*

32h 30m

Average total duration

32h 0m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Direct Options

Compare prices and tickets Greenville, SC to Chicago, IL by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Feb 06
Sat
Feb 07
Sun
Feb 08
Mon
Feb 09
Tue
Feb 10
Wed
Feb 11
Thu
Feb 12

Journey information

Overview: Bus from Greenville, SC to Chicago, IL

USAUSA
USAUSA
Icon of bus

Buses from Greenville, SC to Chicago, IL run on average 6 times per day, taking around 18h 40m. Cheap bus tickets for this journey start at $127 (€101) if you book in advance.

The earliest bus runs at 05:25, the last at 23:50. The fastest bus covers the 561 miles (903 km) distance in 20h 35m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
561 miles (903 km)
Average bus duration
18h 40m
Cheapest ticket price
$127 (€101)
Buses per day
6
Fastest bus
20h 35m
First bus
05:25
Last bus
23:50
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Greenville, SC to Chicago, IL

Find answers to the most common questions about traveling from Greenville, SC to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Greenville, SC to Chicago, IL can start from as little as $127 (€101) when you book in advance. The average bus ticket price for Greenville, SC to Chicago, IL is $146 (€117) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Greenville, SC to Chicago, IL is 20h 35m to travel the 561 miles (903 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Greenville, SC to Chicago, IL leaves at 5:25 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Greenville, SC to Chicago, IL leaves at 11:50 PM.
A trip to Chicago, IL from Greenville, SC is worth doing but not as a day trip with a journey time of 20h 35m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Greenville, SC to Chicago, IL is August.
It's helpful to compare your options as there are 3 ways to travel between Greenville, SC and Chicago, IL including taking a bus, train, and flight.
No, the bus from Greenville, SC to Chicago, IL has no accessibility options.
No, there are no bathrooms on board the bus from Greenville, SC to Chicago, IL.
Some of the most interesting sights to explore in Chicago, IL are:
  • Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
  • Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
  • Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
  • Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
  • Field Museum, a natural history museum with vast exhibits including the famous T. rex skeleton, Sue.
The best things to do in Chicago, IL include:
  • Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
  • Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
  • Take a river cruise to see the city's iconic architecture from a different perspective
  • Attend a live performance at the historic Chicago Theatre
  • Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U.S., offering free admission.
No, bikes are not allowed on board the bus from Greenville, SC to Chicago, IL.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Greenville, SC to Chicago, IL.
No, luggage for the bus from Greenville, SC to Chicago, IL needs to be booked in addition.
No, there are no additional luggage options for the bus from Greenville, SC to Chicago, IL.
Unfortunately, pets are not allowed on the bus from Greenville, SC to Chicago, IL.
No, there are no USB plugs on board the bus from Greenville, SC to Chicago, IL.
No, there is no WiFi on board the bus from Greenville, SC to Chicago, IL.

popular bus stations

Popular bus stations from Greenville, SC to Chicago, IL

Greenville
Chicago
The major bus station for departures in Greenville is Greenville, Woodruff Rd ("Raceway" gas station). Find all the information you need to know about services, amenities and connections at Greenville, Woodruff Rd ("Raceway" gas station) for your trip from Greenville to Chicago.
Greenville, Woodruff Rd ("Raceway" gas station)
information
HomeBusesBuses in USABus tickets to Chicago, ILGreenville, SC to Chicago, IL bus

The Omio App Makes Travel Planning Easy

We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

ios-badge
android-badge
Hand With Phone