Greenville, SC to Chicago, IL bus

Fri, Dec 19
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Itabus
1,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Itabus
1,000+ travel companies
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The cheapest and fastest buses from Greenville, SC to Chicago, IL

Showing times and prices for Dec 23

Cheapest price

$230

Average price

$230

Fastest journey

20 h 30 m

Average duration

20 h 30 m

Buses per day

1

Distance

903 km

Cheap tickets

The best way to find a cheap bus ticket from Greenville, SC to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Greenville, SC to Chicago, IL will cost around $230 if you buy it on the day, but the cheapest tickets can be found for only $230.

Fast buses

Of the 1 buses that leave Greenville, SC for Chicago, IL on Tue, Dec 23, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Tue, Dec 23 the direct buses cover the 903 km distance in an average of 20 h 30 m but if you time it right, some buses will get you there in just 20 h 30 m .

On Tue, Dec 23 the slowest buses will take 20 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

Greyhound
11:45PM20h30
Greenville, SC
08:15PMChicago, IL
$2301One-way
0 transfers

Travel Information

Compare bus, train, and flight for Greenville, SC to Chicago, IL

Omio recommends booking the flight as it is the most popular option from Greenville, SC to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from €76. For those with little time consider booking a flight which can get you there in 5h 57m. The ticket price range depends on the travel mode: a bus costs an average of €76, and a train costs an average of €176.

Distance: 561 miles (903 km)

Compare bus with

Bus
Most popular
Flight
Train

€123

Average price

Cheapest

€242

Average price

€302

Average price

21h 30m

Average total duration

21h 0m

Onboard

+

30m

Additional time*

8h 57m

Average total duration

Fastest

5h 57m

Onboard

+

3h 0m

Additional time*

32h 17m

Average total duration

31h 47m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Direct Options

Compare prices and tickets Greenville, SC to Chicago, IL by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Tue
Dec 23
Wed
Dec 24
Thu
Dec 25
Fri
Dec 26
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Dec 27
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Mon
Dec 29

Journey information

Overview: Bus from Greenville, SC to Chicago, IL

USAUSA
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Icon of bus

Buses from Greenville, SC to Chicago, IL run on average 6 times per day, taking around 21h 0m. Cheap bus tickets for this journey start at $95 (€76) if you book in advance.

The earliest bus runs at 05:45, the last at 23:50. The fastest bus covers the 561 miles (903 km) distance in 20h 30m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
561 miles (903 km)
Average bus duration
21h 0m
Cheapest ticket price
$95 (€76)
Buses per day
6
Fastest bus
20h 30m
First bus
05:45
Last bus
23:50
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Greenville, SC to Chicago, IL

Find answers to the most common questions about traveling from Greenville, SC to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Greenville, SC to Chicago, IL can start from as little as $150 (€120) when you book in advance. The average bus ticket price for Greenville, SC to Chicago, IL is $162 (€130); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Greenville, SC to Chicago, IL bus travel time is 19 h 40 min   for the 559 mile (902 km) long trip, but the duration can vary if you travel on weekends and holidays.
The first bus from Greenville, SC to Chicago, IL leaves at 7: 45AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Greenville, SC to Chicago, IL leaves at 10: 50PM.
The cheapest month for a bus from Greenville, SC to Chicago, IL is November.
It's helpful to compare your options as there are 3 ways to travel to Chicago, IL from Greenville, SC including taking a bus, train or flight.
No, the bus from Greenville, SC to Chicago, IL has no accessibility options.
No, there are no bathrooms on board the bus from Greenville, SC to Chicago, IL.
Some of the most interesting sights to explore in Chicago, IL are:
  • Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
  • Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
  • Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
  • Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
  • Field Museum, a natural history museum with vast exhibits including the famous T. Rex skeleton, Sue.
The best things to do in Chicago, IL include:
  • Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
  • Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
  • Take a river cruise to see the city's iconic architecture from a different perspective
  • Attend a live performance at the historic Chicago Theatre
  • Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U. S. Offering free admission.
No, bikes are not allowed on board the bus from Greenville, SC to Chicago, IL.

To find the cheapest bus tickets for your trip from Greenville, SC to Chicago, IL, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Greenville, SC to Chicago, IL.
    No, luggage for the bus from Greenville, SC to Chicago, IL needs to be booked in addition.
    No, there are no additional luggage options for the bus from Greenville, SC to Chicago, IL.
    Unfortunately, pets are not allowed on the bus from Greenville, SC to Chicago, IL.
    No, there are no USB plugs on board the bus from Greenville, SC to Chicago, IL.
    No, there is no WiFi on board the bus from Greenville, SC to Chicago, IL.

    popular bus stations

    Popular bus stations from Greenville, SC to Chicago, IL

    Greenville
    Chicago
    The major bus station for departures in Greenville is Greenville, Woodruff Rd ("Raceway" gas station). Find all the information you need to know about services, amenities and connections at Greenville, Woodruff Rd ("Raceway" gas station) for your trip from Greenville to Chicago.
    Greenville, Woodruff Rd ("Raceway" gas station)
    information
    HomeBusesBuses in USABus tickets to Chicago, ILGreenville, SC to Chicago, IL bus

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