- Must visit
Greensboro Science Center
A popular family-friendly complex combining an aquarium, museum, and zoo, known for interactive exhibits and broad appeal.
Cheapest price
$46
Average price
$47
Fastest journey
3 h 35 m
Average duration
3 h 40 m
Buses per day
2
Distance
272 km
The best way to find a cheap bus ticket from Greenville, SC to Greensboro, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Greensboro, NC will cost around $47 if you buy it on the day, but the cheapest tickets can be found for only $46.
Of the 2 buses that leave Greenville, SC for Greensboro, NC on Mon, Jun 22, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Jun 22 the direct buses cover the 272 km distance in an average of 3 h 40 m but if you time it right, some buses will get you there in just 3 h 35 m .
On Mon, Jun 22 the slowest buses will take 3 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the bus as it is the most popular option from Greenville, SC to Greensboro, NC among Omio's users. If you are prioritising price take the bus with prices starting from $38. For those with little time consider booking a bus which can get you there in 3h 41m. The ticket price range depends on the travel mode: a bus costs an average of $38, and a flight costs an average of $269.
Distance: 169 miles (272 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$43 Average price Cheapest | $76 Average price | $417 Average price | $39 Average price (fuel + tolls) |
4h 11m Average total duration Fastest 3h 41m Onboard + 30m Additional time* | 5h 27m Average total duration 4h 57m Onboard + 30m Additional time* | 8h 12m Average total duration 5h 12m Onboard + 3h 0m Additional time* | 2h 50m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greenville, SC to Greensboro, NC:
A bus is $33 (€27) less than a train for this route with tickets for a train from Greenville, SC to Greensboro, NC costing on average $76 (€62).
A bus is $374 (€306) less than a flight for this route with tickets for a flight from Greenville, SC to Greensboro, NC costing on average $417 (€341).
Other travel options to Greensboro, NC take longer:
Train takes on average 4h 57m.
Flight takes on average 5h 12m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:00AM | Arrival Time 05:35AM | Duration 3h35 | Departure days Tue, Wed, Fri | Cheapest price $42 |
Operator FlixBus | Departure Time 03:00AM | Arrival Time 06:35AM | Duration 3h35 | Departure days Mon, Thu | Cheapest price $38 |
Operator Greyhound | Departure Time 12:10PM | Arrival Time 03:55PM | Duration 3h45 | Departure days Mon | Cheapest price $46 |
Operator FlixBus | Departure Time 08:15PM | Arrival Time 12:10AM | Duration 3h55 | Departure days Tue, Wed | Cheapest price $39 |
The table below shows live departures for Greenville, SC to Greensboro, NC buses for tomorrow, Monday, June 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:00 AM Greenville, SC | 3h35 | 5:35 AM Greensboro, NC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Greenville, SC to Greensboro, NC run on average 3 times per day, taking around 3h 41m. Cheap bus tickets for this journey start at $38 (€31) if you book in advance.
There are 3 buses per day. The earliest bus runs at 04:55, the last at 23:05. The fastest bus covers the 169 miles (272 km) distance in 3h 35m.
Distance 169 miles (272 km) |
Average bus duration 3h 41m |
Cheapest ticket price $38 (€31) |
Buses per day 3 |
Direct buses 3 |
Fastest bus 3h 35m |
First bus 4:55 AM |
Last bus 11:05 PM |
Cheapest Month Sep |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Wed |
Least Busy Day Wed |
Discover the best of Greensboro — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greensboro trip today.
A popular family-friendly complex combining an aquarium, museum, and zoo, known for interactive exhibits and broad appeal.
A nationally significant museum at the former Woolworth building, interpreting the Greensboro sit-ins and the civil rights movement.
The university art museum with a strong modern and contemporary collection, widely regarded as one of the city’s best cultural stops.
The city’s main walkable core, mixing historic blocks, murals, theaters, museums, and nightlife-oriented public spaces.
A large historic park with trails, monuments, and interpretive stops, combining outdoor walking with Revolutionary War history.
A landscaped public garden with seasonal color, sculptures, and easy paths, popular for photos and quiet walks.
Slow-smoked pork shoulder chopped or pulled and dressed in a tangy vinegar-based sauce, a classic Piedmont and statewide barbecue tradition.
A regional red slaw made with cabbage and a lightly sweet vinegar-tomato dressing, commonly served on barbecue sandwiches across central North Carolina.
Fluffy Southern biscuits filled with salty cured ham, a breakfast staple in North Carolina and a familiar comfort food in Greensboro.
A popular casual spot recognized for creative burgers, good beer selection, and lively neighborhood energy.
A polished bistro at Proximity Hotel known for seasonal American fare, strong brunch, and an upscale yet relaxed setting.
An established restaurant offering European-influenced American cuisine, dependable service, and a refined dining room popular for dinner and brunch.
Costs are generally moderate for U.S. travel, with affordable dining and parking, while hotels vary by season and events.
Tip 18-20% at restaurants; 20%+ for excellent service. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
Find answers to the most common questions about traveling from Greenville, SC to Greensboro, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greensboro, NC, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need