- Must visit
National Air and Space Museum
This world-class museum presents aviation and space history through iconic aircraft, spacecraft, and hands-on science exhibits.
The best way to find a cheap bus ticket from Greenville, SC to Washington, DC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Washington, DC will cost around $88 if you buy it on the day, but the cheapest tickets can be found for only $63.
On Wed, Nov 04, we found 4 buses from Greenville, SC to Washington, DC, including 4 direct services.
On Wed, Nov 04 the direct buses cover the 655 km distance in an average of 11 h 9 m but if you time it right, some buses will get you there in just 9 h 55 m .
On Wed, Nov 04 the slowest buses will take 12 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Greenville, SC to Washington, DC run on average 5 times per day, taking around 11h 18m. Cheap bus tickets for this journey start at $61 if you book in advance.
There are 5 buses per day. The earliest bus runs at 00:30, the last at 22:45. The fastest bus covers the 406 miles (655 km) distance in 9h 50m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Greenville, SC to Washington, DC.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:00AM | Arrival Time 11:55AM | Duration 9h55 | Departure days Wed | Cheapest price $75 |
Operator FlixBus | Departure Time 03:00AM | Arrival Time 12:55PM | Duration 9h55 | Departure days Wed, Thu, Sat | Cheapest price $92 |
Operator Greyhound | Departure Time 03:25AM | Arrival Time 04:25PM | Duration 13h00 | Departure days Mon, Thu, Sun | Cheapest price $82 |
Operator Greyhound | Departure Time 07:10AM | Arrival Time 06:35PM | Duration 11h25 | Departure days Mon, Thu, Sun | Cheapest price $73 |
Operator Greyhound | Departure Time 11:00AM | Arrival Time 11:05PM | Duration 12h05 | Departure days Mon, Thu, Sun | Cheapest price $73 |
Operator Greyhound | Departure Time 11:10AM | Arrival Time 10:35PM | Duration 11h25 | Departure days Wed, Fri | Cheapest price $96 |
Operator Greyhound | Departure Time 11:25AM | Arrival Time 10:25PM | Duration 11h00 | Departure days Wed | Cheapest price $63 |
Operator FlixBus | Departure Time 12:55PM | Arrival Time 11:20PM | Duration 10h25 | Departure days Thu, Sun | Cheapest price $68 |
Operator Greyhound | Departure Time 03:50PM | Arrival Time 04:05AM | Duration 12h15 | Departure days Wed | Cheapest price $84 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 03:05AM | Duration 10h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $71 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 03:15AM | Duration 10h00 | Departure days Fri | Cheapest price $104 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 07:25AM | Duration 9h50 | Departure days Mon, Thu, Sun | Cheapest price $68 |
The table below shows live departures for Greenville, SC to Washington, DC buses for tomorrow, Wednesday, November 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:00 AM Greenville, SC | 9h55 | 12:55 PM Washington, DC | 0 transfersDirect | |
![]() | 11:10 AM Greenville, SC | 11h25 | 10:35 PM Washington, DC | 0 transfersDirect | |
![]() | 11:25 AM Greenville, SC | 11h00 | 10:25 PM Washington, DC | 0 transfersDirect | |
![]() | 3:50 PM Greenville, SC | 12h15 | 4:05 AM Washington, DC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Greenville, SC to Washington, DC with FlixBus and Greyhound. Overnight buses available on this route with FlixBus and Greyhound. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Washington, DC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Washington, DC trip today.
This world-class museum presents aviation and space history through iconic aircraft, spacecraft, and hands-on science exhibits.
Housed in a Beaux-Arts building, this museum explores natural wonders with dinosaurs, gems, fossils, and global biodiversity.
A landmark museum documenting African American history and culture through powerful exhibitions, artifacts, and storytelling.
The National Mall is Washington's grand civic promenade, lined with museums, memorials, and classic views ideal for first-time visitors.
Georgetown charms with historic streets, rowhouses, waterfront paths, and independent shops that make it one of the city's best walking areas.
The Tidal Basin loop offers famous cherry blossoms, water views, and easy access to several of Washington's most iconic memorials.
Half-smoke sausage, usually smoked pork and beef, served on a bun with chili, mustard, and onions. It is DC's signature street food, strongly tied to Ben's Chili Bowl.
Jumbo slice is an oversized late-night pizza slice popular in Adams Morgan. It is a recognizable DC nightlife food known for its huge foldable portions.
Mumbo sauce is a sweet tangy red sauce commonly served with fried chicken and wings at DC carryouts. It is a beloved local condiment with roots in Black DC food culture.
Acclaimed fine-dining restaurant focused on Mid-Atlantic ingredients and refined tasting menus in an elegant, contemporary dining room.
Polished seafood institution at the municipal fish market, best known for regional oysters, crab cakes, and classic Chesapeake flavors.
Historic casual landmark famous for half-smokes, chili, and a classic diner feel. A must for trying DC's best-known street food tradition.
DC is pricier than many US cities. Hotels and dining run high in central areas, but Metro and many free museums help balance daily travel costs.
Tip 18-20% at restaurants, more for great service. Taxis usually 10-15%. Cafes: round up or add $1-2.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Washington, DC.
Find answers to the most common questions about traveling from Greenville, SC to Washington, DC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Washington, DC, this guide helps you travel smarter and with confidence.
