- Must visit
Smithsonian National Museum of Natural History
One of the most visited museums in the city, known for dinosaur fossils, the Hope Diamond, and major natural science collections.
Cheapest price
$71
Average price
$95
Fastest journey
9 h 50 m
Average duration
10 h 50 m
Buses per day
6
Distance
655 km
The best way to find a cheap bus ticket from Greenville, SC to Washington, DC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Washington, DC will cost around $95 if you buy it on the day, but the cheapest tickets can be found for only $71.
Of the 6 buses that leave Greenville, SC for Washington, DC on Mon, Jun 22, 6 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Jun 22 the direct buses cover the 655 km distance in an average of 10 h 50 m but if you time it right, some buses will get you there in just 9 h 50 m .
On Mon, Jun 22 the slowest buses will take 12 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus
FlixBus

FlixBus
FlixBus
FlixBus

Omio recommends booking the train as it is the most popular option from Greenville, SC to Washington, DC among Omio's users. If you are prioritising price take the bus with prices starting from $64. For those with little time consider booking a flight which can get you there in 2h 25m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $64, and a flight costs an average of $92.
Distance: 406 miles (655 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$96 Average price Cheapest | $170 Average price | $253 Average price | $95 Average price (fuel + tolls) |
11h 17m Average total duration 10h 47m Onboard + 30m Additional time* | 11h 56m Average total duration 11h 26m Onboard + 30m Additional time* | 5h 25m Average total duration Fastest 2h 25m Onboard + 3h 0m Additional time* | 7h 18m Average total duration (door-to-door) |
0.7 - 1.6kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest | 2.0 - 3.9kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Greenville, SC to Washington, DC:
A bus is $74 (€60) less than a train for this route with tickets for a train from Greenville, SC to Washington, DC costing on average $170 (€139).
A bus is $156 (€128) less than a flight for this route with tickets for a flight from Greenville, SC to Washington, DC costing on average $253 (€207).
Other travel options to Washington, DC take longer:
Bus takes on average 10h 47m.
Train takes on average 11h 26m.
You'll arrive about -4h -29m sooner (10h 47m by bus vs 7h 18m by car) and save roughly $-1.34 (€-1.10) compared to fuel and tolls ($96 (€79) vs $95 (€78)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by Greyhound, FlixBus.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:25AM | Arrival Time 04:25PM | Duration 13h00 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $72 |
Operator Greyhound | Departure Time 07:10AM | Arrival Time 06:35PM | Duration 11h25 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $70 |
Operator Greyhound | Departure Time 11:00AM | Arrival Time 11:05PM | Duration 12h05 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $72 |
Operator FlixBus | Departure Time 12:15PM | Arrival Time 10:15PM | Duration 10h00 | Departure days Mon, Thu, Fri, Sun | Cheapest price $61 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 02:15AM | Duration 10h00 | Departure days Everyday | Cheapest price $66 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 07:25AM | Duration 9h50 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $59 |
The table below shows live departures for Greenville, SC to Washington, DC buses for today, Sunday, June 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:25 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 13h00 | 4:25 PM Washington, Columbus Circle, Union Station | 0 transfersDirect | |
![]() | 7:10 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 11h25 | 6:35 PM Washington, Columbus Circle, Union Station | 0 transfersDirect | |
![]() | 11:00 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 12h05 | 11:05 PM Washington, Columbus Circle, Union Station | 0 transfersDirect | |
FlixBus | 12:15 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 10h00 | 10:15 PM Washington, Columbus Circle, Union Station | 0 transfersDirect | |
FlixBus | 4:15 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 10h50 | 3:05 AM Washington, Columbus Circle, Union Station | 0 transfersDirect | |
FlixBus | 9:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 9h50 | 7:25 AM Washington, Columbus Circle, Union Station | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Greenville, SC to Washington, DC run on average 5 times per day, taking around 10h 47m. Cheap bus tickets for this journey start at $64 (€53) if you book in advance.
There are 5 buses per day. The earliest bus runs at 00:30, the last at 22:45. The fastest bus covers the 406 miles (655 km) distance in 9h 55m.
Distance 406 miles (655 km) |
Average bus duration 10h 47m |
Cheapest ticket price $64 (€53) |
Buses per day 5 |
Direct buses 5 |
Fastest bus 9h 55m |
First bus 12:30 AM |
Last bus 10:45 PM |
Cheapest Month Mar |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 35 days |
Discover the best of Washington — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Washington trip today.
One of the most visited museums in the city, known for dinosaur fossils, the Hope Diamond, and major natural science collections.
Flagship museum for aviation and space exploration, featuring iconic aircraft, spacecraft, and interactive exhibits.
Powerful museum covering African American history, culture, and achievements through immersive exhibitions.
The city’s central ceremonial landscape, lined with major museums, memorials, and classic Washington views.
Historic neighborhood of cobbled streets, waterfront paths, and Federal-era architecture, ideal for walking and photos.
Scenic waterfront loop famous for cherry blossoms and close-up access to several major memorials.
Washington’s signature sausage, usually smoky and spicy, served on a bun with chili, mustard, and onions. It is one of the city’s most iconic street foods.
A sweet-tangy sauce strongly associated with Washington carryout culture, commonly paired with fried chicken and fries. It is a distinctive local flavor locals recognize immediately.
Regional blue crab from nearby Chesapeake waters, often served steamed and heavily seasoned. It reflects the Mid-Atlantic seafood traditions closely tied to Washington dining.
An established downtown institution known for oysters, crab cakes, and classic American seafood near the White House, with an elegant old-school atmosphere.
Busy, established French brasserie in Logan Circle known for polished service, a classic dining room, and consistently popular bistro dishes.
Historic casual landmark on U Street, famous for half-smokes, chili dogs, and classic Washington comfort food in a lively, nostalgic setting.
Prices are high by U.S. standards, especially for hotels and dining near central areas and major attractions.
Tip 18-20% at restaurants. USD 1-2 per drink at bars. Taxis: 10-15% or round up. Hotel staff: USD 2-5. Tips are expected for table service.
Official public transport app
L'Enfant Plaza, Washington, DC -> Union Station, Washington, DC
Find answers to the most common questions about traveling from Greenville, SC to Washington, DC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Washington, DC, this guide helps you travel smarter and with confidence.

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